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Dima KozakovView profile

Research Professor

• Macromolecular recognition
• Protein-protein interaction networks
• Drugability of genome
• +3 more

Dima Kozakov is a Research Professor in the Department of Biomedical Engineering at Boston University. He holds a PhD in Biomedical Engineering from Boston University and an M.Sci. in Applied Mathematics and Physics from the Moscow Institute of Physics and Technology. His research focuses on macromolecular recognition, signaling protein-protein interaction networks, genome drugability, and protein design. He is affiliated with the Research Faculty at BU and has contributed to advancements in computational methods for structural biology and drug discovery. His work integrates advanced Fourier and optimization techniques to explore macromolecular interaction landscapes, including structure determination of macromolecular complexes from low-resolution data and validation of protein interaction networks. He develops methods for fragment-based drug design, identifying cryptic binding sites amenable to small molecule inhibition in cancer pathways, and designs peptidic chaperones for crystallization. His contributions include the ClusPro docking server and FTMap pharmacophore identification tools. Recent publications highlight his exploration of ligand interaction landscapes in E. coli, targeted protein degradation mechanisms, and AlphaFold-based structural predictions. He investigates multiomic profiles of immune cells and metabolic reprogramming in disease contexts. His research emphasizes druggable site identification, computational modeling of protein interactions, and advancing machine learning applications in structural biology. Key innovations include MHC-Fine for precise MHC-peptide complex prediction and E-FTMap for fragment-based drug discovery. His work bridges computational methods with experimental validation, addressing challenges in protein structure prediction and drug target identification. Kozakov collaborates on projects like the CASP15 CAPRI experiment, assessing computational methods for protein complex modeling.

• Medical Sociology
• Health Care Access
• Health Disparities
• +9 more

Matthew Carlson is the Associate Dean for Undergraduate Programs at the College of Liberal Arts and Sciences , Portland State University. His primary academic affiliation is with the Sociology Department , where he serves as an Associate Professor . As a medical sociologist, his research focuses on healthcare access, quality, and disparities, with a strong emphasis on vulnerable populations and policy implications. His scholarly work spans Medicaid policy, substance abuse treatment outcomes, domestic violence intervention, and social determinants of health. Publications highlight trends in public health policy evaluation, health services research, and social justice in healthcare delivery. Notable areas include insurance continuity, maternal health, and behavioral health interventions. As an administrator, he oversees undergraduate enrollment management, recruitment, retention, and curricular development. Despite his leadership roles, no specific scientific awards or student advising records were identified in the provided materials. His contributions bridge academic sociology with practical healthcare policy analysis.

• Bone Metabolism
• Osteoporosis
• Atypical Femur Fractures
• +7 more

Hanh Nguyen is a Research Fellow at the Faculty of Medicine, Monash University, affiliated with Monash Health. Her work is focused on clinical and translational research in bone metabolism, particularly atypical femur fractures, osteoporosis, and related endocrine disorders. Her research interests span bone biomechanics , genetics of bone diseases , hypophosphatasia , and the application of deep learning in medical imaging for fracture detection. She employs advanced methodologies in radiographic analysis and patient cohort studies to improve diagnosis and understanding of skeletal disorders. The recent publications highlight a strong trend in integrating AI-driven diagnostics with clinical endocrinology , particularly in identifying atypical fractures and metabolic bone conditions. Her work bridges computational innovation with patient-centered outcomes, contributing to both technological and clinical advancements. No scientific awards are explicitly mentioned in the provided text. Hanh Nguyen actively collaborates with leading researchers such as Professor Peter R. Ebeling, Dr. Christian Girgis, and Professor Roland Zebaze. While no formal students or grant details are listed, her consistent output in high-impact journals suggests active involvement in research mentoring and project leadership within the Monash endocrinology research group. She is part of a broader research network focused on bone health and endocrine disorders at Monash, contributing to UN Sustainable Development Goals related to good health and well-being. Her team leverages clinical data, imaging, and genetic analysis to advance understanding of skeletal fragility and metabolic bone diseases.

Lewei Allison LinView profile

Associate Professor

• Addiction Psychiatry
• Substance Use Disorders
• Telehealth Interventions
• +3 more

Dr. Lewei Allison Lin is an Associate Professor in the Department of Psychiatry at the University of Michigan Medical School and a Research Scientist at the VA Ann Arbor Healthcare System. She serves as Co-Director of the Michigan Addiction Research Center for Equity (MI-ACRE) and Director of the Addiction Psychiatry Fellowship Program, while maintaining clinical practice in addiction psychiatry at the VA Ann Arbor Healthcare System. Education: Addiction Psychiatry Research & Clinical Fellow, University of Michigan Medical School Adult Psychiatry Residency, University of Michigan Medical School M.D., Yale University School of Medicine B.S. in Chemical Engineering and Economics, Massachusetts Institute of Technology Dr. Lin's research program centers on leveraging large healthcare datasets to identify actionable disparities in substance use disorder treatment access and quality, with emphasis on developing telehealth-delivered interventions for real-world implementation. Her work prioritizes overdose risk mitigation, care improvement for patients with comorbid mental health/chronic pain conditions, and equitable access to evidence-based addiction treatments across diverse populations. She employs mixed-methods approaches to bridge implementation science with clinical practice. Analysis of Dr. Lin's publication record reveals consistent focus on telehealth scalability in addiction care, health equity metrics, and integrated treatment models for polysubstance use disorders. Her recent work increasingly addresses the evolving overdose crisis through structural interventions targeting social determinants of health, with strong emphasis on veteran populations and underserved communities. Methodologically, her studies combine epidemiological analysis with pragmatic clinical trial designs. Scientific Awards: Presidential Early Career Award for Scientists and Engineers (PECASE) As Director of the U-M Addiction Psychiatry Fellowship Program, Dr. Lin mentors fellows in clinical addiction psychiatry and research methodology. She has held significant leadership roles including Immediate Past President of the Michigan Society of Addiction Medicine and Chair of the American Academy of Addiction Psychiatry Research Committee. Her research is supported by Department of Veterans Affairs and National Institutes of Health grants focused on implementation science and health services research in addiction treatment. Dr. Lin co-directs MI-ACRE, a multidisciplinary research center addressing systemic barriers in addiction care through community-engaged partnerships. The center develops and tests scalable interventions for high-need populations, with current projects examining telehealth policy impacts, pharmacist-led MOUD expansion, and integrated care models for co-occurring stimulant-opioid use disorders.

Seth FieldView profile

Professor

• Cancer Biology
• Cell Biology
• Membrane Trafficking
• +3 more

Seth Field is a Professor in the Department of Medicine at Case Western Reserve University School of Medicine. He is a member of the Developmental Therapeutics Program at the Case Comprehensive Cancer Center and an investigator at the Harrington Discovery Institute. His research focuses on the cell biology of cancer, particularly the role of Golgi secretory machinery in oncogenesis. Dr. Field's work investigates how components of the Golgi apparatus contribute to cancer progression and identifies molecular vulnerabilities for targeted therapies. His laboratory has discovered that Golgi-associated proteins like GOLPH3 are frequently amplified in cancers, driving tumor growth. They are developing small molecule inhibitors targeting these pathways, offering novel therapeutic approaches orthogonal to existing treatments. Dr. Field also holds the Becky Hennessy Endowed Master Clinician in Breast Cancer Genomics and practices as an attending physician in Endocrinology at University Hospitals. Research interests include membrane trafficking mechanisms, phosphatidylinositol signaling, and oncogenic pathways. Key findings link GOLPH3 to DNA damage responses and cell migration, with implications for cancer metastasis. His work bridges basic cell biology and translational oncology, emphasizing drug discovery.

Rachèl SprosView profile

Researcher

• Archaeology
• Environmental Chemistry
• Isotope Analysis
• +3 more

Rachèl Spros is an Education/Research Officer in Chemistry and Archaeology at Vrije Universiteit Brussel (VUB), specializing in isotopic analysis of human remains to reconstruct historical mobility and dietary patterns. She holds a B.A. in Art Sciences and Archaeology from VUB (2018) and an M.Sc. in Archaeological Science from the University of Oxford (2019). Her research focuses on medieval urban populations, particularly in Ypres (Belgium), using multi-isotope approaches to study migration, health, and social structures. Key projects include the Make-Up of the City project analyzing 13th-14th century skeletal remains, and Merovingian kinship studies through DNA and isotope analyses. Notable contributions include identifying Ypres' highest oxygen isotope values in northwestern Europe and discovering genetic fusion between populations in Flanders. She co-authored 21 peer-reviewed articles and datasets, receiving awards for best student poster (2021) and interdisciplinary research (2024). Research Themes: Isotopic mobility, medieval urbanization, bioarchaeological methods Key Collaborations: Snoeck Lab (VUB), University of Cambridge, University of Ljubljana

Raquel Marchán-RivadeneiraView profile

Academic

• Ecological Genomics
• Evolutionary Biology
• Adaptive Variation
• +7 more

Raquel Marchán-Rivadeneira is a Research Assistant Professor in the Department of Biological Sciences at Ohio University’s College of Arts and Sciences. She also serves as an Assistant Investigator at the Institute for Molecular Medicine and Aging and as Adjunct Faculty in the Translational Biomedical Sciences Program. Her work bridges evolutionary biology and biomedical discovery, with a strong emphasis on ecological genomics and natural products research. Education: Ph.D. in Biology, Texas Tech University M.Sc. in Biology, Texas Tech University B.S. in Biology, Pontificia Universidad Católica del Ecuador, Quito, Ecuador Dr. Marchán-Rivadeneira’s research focuses on understanding how natural populations adapt across environmental gradients using integrative approaches combining genomics and phenotypic analyses. She also explores biological diversity as a proxy for chemical diversity, aiming to identify novel antimicrobial, anticancer, and antiviral compounds from natural sources. Her work spans conservation genetics, biosynthesis, and the application of gene-editing tools like CRISPR-Cas13 in antiviral strategies. Recent publications highlight her contributions to drug discovery, particularly in polycyclic tetramate macrolactams and rapid antibiotic development. Her research also includes landscape genetics in amphibians, speciation dynamics in reptiles, and morphological responses to environmental stressors such as radiation. These works reflect a strong interdisciplinary trend integrating molecular biology, evolutionary ecology, and biomedicine. Scientific Awards: No awards listed in available text. Dr. Marchán-Rivadeneira is actively involved in research and collaborative projects, though specific details on grants or student mentorship are not provided. Her affiliations with both basic and translational research programs suggest engagement in funded research and academic training. She is likely involved in mentoring graduate students and securing external funding, given the scope and publication output of her work. She conducts her research at the Konneker Research Center on Ohio University’s Athens campus, where she maintains a laboratory focused on molecular and evolutionary studies. Her dual roles in the Institute for Molecular Medicine and Aging and the Translational Biomedical Sciences Program indicate integration into interdisciplinary teams working at the intersection of evolution and human health.

• Functional Neuroimaging
• Machine Learning
• Clinical Psychiatry

Michele Bertocci, PhD, serves as Supervising Faculty for the InCabs Imaging Study at the University of Pittsburgh School of Medicine's Department of Psychiatry. His research focuses on identifying markers of bipolar disorder through functional neuroimaging, machine learning, and clinical psychiatry methodologies. The study integrates MRI, actigraphy, and questionnaire data to advance early detection and personalized treatment strategies. Dr. Bertocci oversees a rigorous student research program requiring a 3.0 GPA, specific coursework (Statistics, Research Methods), and training in crisis management. Students contribute to data analysis, lab activities, and collaborative projects leading to poster/manuscript outputs. Recruitment emphasizes alignment with the student's career goals and teamwork preferences via structured interviews. No academic awards or grants are explicitly listed in the provided text. The lab's mission centers on translational psychiatry research with a focus on psychiatric disorders' neurobiological underpinnings.

John G. PurdyView profile

Associate Professor

• Virology
• Metabolomics
• Lipid Metabolism
• +3 more

John G. Purdy is an Associate Professor of Immunobiology and Cancer Biology at the University of Arizona, where he has been a faculty member since October 2015. He is also a Faculty Fellow at the BIO5 Institute, an interdisciplinary research center focused on solving complex problems in health, agriculture, and environment. Dr. Purdy earned his undergraduate degree from Pacific University and completed his Ph.D. at Penn State University College of Medicine. He then pursued postdoctoral training in metabolomics at the Lewis-Sigler Institute for Integrative Genomics, Princeton University, working with Drs. Joshua Rabinowitz and Thomas Shenk. Dr. Purdy's research focuses on understanding how viruses, particularly human cytomegalovirus (HCMV), remodel host cell metabolic and lipid environments to facilitate their replication. His work aims to identify key cellular and viral targets for the development of novel antiviral therapies. The Purdy Lab employs biochemical, molecular, and genetic approaches to analyze metabolomic and lipidomic dynamics during viral infection, with a particular emphasis on fatty acid elongation and very long-chain fatty acid synthesis. Analysis of Dr. Purdy's recent publications reveals a consistent focus on virus-host metabolic interactions, particularly how HCMV manipulates lipid metabolism. His work spans multiple disciplines including virology, metabolomics, lipidomics, and cell biology, with applications to understanding viral pathogenesis and developing antiviral strategies. A recurring theme is the role of very-long-chain fatty acids in viral replication, with significant contributions to understanding how viruses rewire host metabolic pathways. R01 Award (2021) - Metabolite mediated signaling in cell-to-cell spread of HCMV R01 Award (2021) - HCMV reprogramming of lipid metabolism Dr. Purdy leads the Purdy Lab at the University of Arizona, which includes postdoctoral researchers, laboratory coordinators, graduate students, and undergraduate volunteers. Current lab members include Dr. Rebekah Mokry (Postdoctoral Research Associate), Nathan Schmidt (Laboratory Coordinator), and several graduate and undergraduate students. The lab has successfully mentored multiple students to completion of their degrees, including Dr. Yuecheng Xi who completed her PhD in 2021. Dr. Purdy was promoted to Associate Professor with Tenure in July 2022, reflecting his significant contributions to research and education.

• Neuroscience
• Neurology
• Ion Channels
• +7 more

Stephen Waxman is the Bridget Flaherty Professor of Neurology, Neuroscience, and Pharmacology at Yale School of Medicine. He serves as Director of the Center for Neuroscience and Regeneration Research and previously chaired the Department of Neurology from 1986 to 2009. He has held faculty positions at Harvard, MIT, and Stanford prior to joining Yale. MD, Albert Einstein College of Medicine (1972) PhD, Albert Einstein College of Medicine (1970) Residency, Boston City Hospital (1975) Clinical Fellowship, Harvard Medical School (1975) Postdoctoral Fellowship, MIT (1975) Dr. Waxman’s research focuses on the molecular basis of nervous system disorders, particularly ion channel function in multiple sclerosis, spinal cord injury, and neuropathic pain. His pioneering work has elucidated how sodium channel plasticity contributes to recovery in demyelinated axons and has identified specific ion channel mutations underlying hereditary pain syndromes. He integrates molecular biology, genetics, electrophysiology, and computational modeling to develop novel therapies. His recent publications highlight advancements in automated electrophysiology, pharmacogenomics, and the discovery of new analgesic targets such as Nav1.8 and TRPM8. His work on non-addictive pain medications is currently being tested in Phase II clinical trials, and he has identified ion channels involved in osteoarthritis and pain resilience. Notable scientific awards include: Member, National Academy of Medicine Julius Axelrod Prize, Society for Neuroscience Mitchell Max Award, American Academy of Neurology Soriano Award, American Neurological Association British Physiological Society Annual Prize Dystel Prize, American Academy of Neurology Dr. Waxman has trained numerous scientists who now lead research teams worldwide. He has served on editorial boards of leading journals including Annals of Neurology , Brain , Journal of Physiology , and Nature Reviews Neurology , and is Editor of The Neuroscientist . His laboratory is actively involved in the PROPANE Neuropathy Genomics Project, CRS Injury and Repair, and the International Pain Genomics Consortium. He leads the Waxman Lab at the Center for Neuroscience and Regeneration Research, which employs state-of-the-art techniques in molecular imaging, stem cell models, and high-throughput electrophysiology to study nerve excitability and develop targeted therapies for neurological disorders.

• Professional Learning
• Education
• Teacher Development
• +2 more

Gareth Dart is a Senior Lecturer in Professional Learning in Education at the Faculty of Life Sciences and Education. His role focuses on advancing educational practice through professional development initiatives. His research interests center on professional learning and education , particularly in the context of teacher development and pedagogical improvement. These areas reflect his commitment to enhancing educational outcomes through structured learning frameworks. Gareth Dart has not published any articles in the provided text, so no publication trends can be identified. No scientific awards or honors are listed in the available information. There is no information available regarding student supervision, grants, laboratory affiliations, or research teams.

Katie SimmonsView profile

Lecturer

• Structural Pharmacology
• Medicinal Chemistry
• Chemical Biology
• +7 more

Dr. Katie Simmons is a Lecturer in Structural Pharmacology at the School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds. Her research integrates computational and experimental approaches to identify bioactive molecules for early-stage drug discovery, targeting diseases such as Type 2 Diabetes, epilepsy, and cardiometabolic disorders. Research Interests: Medicinal Chemistry and Ligand Design Molecular Modelling and In Silico Screening Chemical Biology and Fragment-Based Discovery Molecular Biology and Assay Development Targeting Integrins, Ion Channels, and Receptor Hybrids Her work emphasizes the development of therapeutic leads through collaborations within the University of Leeds and with industrial partners. Key projects include RGD-mimetics for insulin sensitization, fluorine-containing inhibitors for cardiovascular protection, potassium channel blockers for epilepsy, and modulators of IR-IGF1R hybrids. Research Trends in Publications: Her recent scholarly output centers on early-stage drug discovery, combining computational prediction with synthetic chemistry and biophysical validation. Articles reflect a strong focus on structural pharmacology, targeting protein-protein interactions, receptor modulation, and fragment-based screening, particularly using NMR and in silico methods. Scientific Contributions: Lead discovery for cardiometabolic diseases Development of novel therapeutics for rare epilepsies Innovation in fluorine-based NMR screening Tool compound generation for hybrid receptor studies Advising and Research Support: Dr. Simmons leads an active research group focused on structural pharmacology and drug discovery. She mentors students and researchers in interdisciplinary projects combining computational modelling, synthetic chemistry, and molecular biology. Her work is supported by academic collaborations and aims to translate findings into industrial partnerships for further development. Laboratory and Research Environment: Based in Garstang 6.44F at the University of Leeds, her lab utilizes a range of techniques including molecular modelling, small molecule synthesis, assay development, and biophysical methods such as NMR. The group collaborates widely across institutions to advance therapeutic leads.

Michal K. StachowiakView profile

Professor

• Bioinformatics
• Cell growth, differentiation and development
• Epigenetics
• +9 more

Dr. Michal K. Stachowiak is a Professor and Director of the Molecular and Structural Neurobiology Program at the University at Buffalo's Jacobs School of Medicine & Biomedical Sciences. He also leads the Gene Therapy Program and Stem Cell SCEF within the Department of Pathology and Anatomical Sciences. His work focuses on genomic regulation during neurodevelopment, schizophrenia pathophysiology, and translational applications of stem cells and optogenetics. Research interests include: bioinformatics applications in neurobiology, epigenetic mechanisms in cell development, gene therapy strategies, and the role of nuclear FGFR1 signaling in neuronal programming. He pioneered cerebral organoid models to study neurodevelopmental disorders and developed optogenomic interfaces merging light-based control with genomic networks. Recent work emphasizes phase-zero clinical platforms using organoid models for disease modeling, and nanotechnology-based approaches for precise stem cell regulation. His interdisciplinary studies bridge molecular biology, engineering, and clinical translation - highlighted by innovations in neuroengineering optical theranostics and systems genome analysis. Key contributions include identifying TNFα's role in schizophrenia-like organoid abnormalities, demonstrating genome architecture's dependence on nuclear FGFR1, and creating optogenetic tools for neuronal network control. His lab's technologies include ORMosil nanoparticles for gene delivery and Vis/NIR spectroscopy-based diagnostic platforms for organoid assays.

• Neurodegenerative Diseases
• Alzheimer's Disease
• Protein Aggregation
• +5 more

Meenakshisundaram Balasubramaniam serves as an Assistant Professor in the Department of Geriatrics within the College of Medicine at the University of Arkansas for Medical Sciences. His research is centered on neurodegenerative mechanisms with a focus on Alzheimer's disease pathology, protein aggregation dynamics, and autophagy regulation. As a key collaborator in the Shmookler Reis laboratory, he contributes to interdisciplinary investigations spanning computational biology, molecular pharmacology, and translational neuroscience. Dr. Balasubramaniam's research interests encompass: Protein aggregation mechanisms in Alzheimer's and related dementias Computational drug repurposing and target identification Autophagy-lysosomal pathway dysfunction in neurodegeneration Neuroinflammation and cytokine signaling cascades Structural modeling of neurodegenerative disease targets His work integrates advanced computational approaches with experimental validation to identify therapeutic interventions for age-related neurological disorders. Analysis of recent publications reveals strong thematic continuity in targeting protein aggregation pathways across neurodegenerative conditions. His research demonstrates particular innovation in repurposing existing drugs (e.g., ezetimibe, TDZD analogs) to modulate aggregation mechanisms, with consistent application of computational modeling to predict drug-target interactions. The work spans from fundamental molecular mechanisms to preclinical validation in diverse model systems. Scientific recognition includes: Outstanding doctoral student research award from the Engineering and Information Technology program at the University of Arkansas at Little Rock (2016) As Co-Investigator on multiple NIH-funded projects including R01AG084472 and P01AG012411, Dr. Balasubramaniam contributes to major initiatives investigating neuroinflammation, protein aggregates, ApoE4 drug targeting, and autophagy rescue in Alzheimer's pathogenesis. His collaborative approach extends across neuroscience, oncology, and computational biology domains. He operates within the Shmookler Reis laboratory environment, which maintains strong connections between computational modeling groups and experimental neuroscience teams. This integrated approach facilitates rapid translation of in silico predictions to in vitro and in vivo validation, particularly using C. elegans and mammalian cell models for neurodegenerative disease mechanisms.

Silje HjelmelandView profile

Research Fellow

• Local governance
• Transparency in politics
• Policy development
• +5 more

Silje Hjelmeland is a PhD Research Fellow at the Department of Political Science and Management, University of Agder, specializing in democracy and citizenship. Her doctoral research investigates openness and transparency practices in political decision-making across Norwegian municipalities, incorporating comparative analysis with Danish counterparts to identify causal variations in governance approaches. The study employs theoretical frameworks distinguishing “front” and “back” stages of policy-making while examining tensions between democratic control, deliberation, and accountability. Education Background Bachelor of Political Science, University of Agder Master of Political Science, University of Agder Research Focus Hjelmeland’s expertise centers on empirical analysis of formal and informal municipal policy processes, with emphasis on system capacity constraints and democratic trade-offs in transparency. Her work bridges Nordic comparative governance and welfare state adaptation, particularly exploring how institutional structures influence citizen engagement in local politics. Key interests include democratic deliberation mechanisms, accountability in public administration, and cross-municipal variation in policy implementation, reflecting strong roots in contemporary political science methodology. Publication Trends Her scholarly output demonstrates applied research convergence between academic theory and municipal governance practice. The 2023 co-authored report on workplace diversity connects to her broader analysis of transparency in welfare systems, revealing consistent focus on public sector management challenges within Nordic contexts. Publications emphasize practical policy implications rather than purely theoretical work, with emerging interest in quantitative-comparative approaches across Scandinavian municipalities. Professional Activities Hjelmeland concurrently serves as a part-time (25%) senior analyst at Oxford Research, dedicated to local governance and welfare projects. This industry engagement provides real-world data for her doctoral work, though no research grants or student advising responsibilities are documented. Her dual role highlights integration of academic research with practical policy analysis in public administration.