Glenn J. McGarveyView profile
Professor
- Carbohydrate-Based Molecular Recognition
- Complex Glycoconjugate Synthesis
- Molecular Glycosciences
- +3 more
Glenn J. McGarvey is a Professor in the Department of Chemistry at the University of Virginia's School of Arts & Sciences, specializing in Molecular Glycosciences. His research focuses on the synthesis and application of complex carbohydrates for biomedical interventions. His research interests center on Carbohydrate-Based Molecular Recognition and Complex Glycoconjugate Synthesis , with emphasis on cellular communication mechanisms involving cell surface carbohydrates conjugated to proteins and lipids. These structures mediate critical processes in normal cellular function and diseases including rheumatoid arthritis, viral/bacterial infections, and cancer metastasis. His work bridges synthetic organic chemistry with biological applications through the development of: Synthetic cancer vaccines targeting cell surface carbohydrate antigens C-glycoside oligosaccharide/peptide hybrids for DNA recognition Unnatural glycopeptide structures for therapeutic applications Dr. McGarvey's publication record demonstrates expertise in stereoselective glycoside synthesis and C-glycosyl amino acid development, with research trends indicating sustained focus on carbohydrate-based molecular recognition systems for disease intervention. His work consistently integrates synthetic methodology development with biological targeting applications. His laboratory actively investigates the dense stereochemical properties of carbohydrates to generate novel biorecognition molecules, with particular emphasis on creating new therapeutic approaches for modifying biological function in disease contexts.











