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Mark NiedreView profile

Professor

• Biomedical Optics
• Non-invasive Imaging
• Circulating Tumor Cell Detection
• +4 more

Dr. Mark Niedre is an Associate Dean of PhD Education and COE Distinguished Professor of Bioengineering at Northeastern University's College of Engineering. His research focuses on biomedical optics, non-invasive imaging, and the detection of rare circulating cells (e.g., circulating tumor cells) using diffuse optical techniques. He leads the Biomedical Optics Research Group, which integrates optical engineering, biology, and signal processing to develop innovative diagnostic tools. Dr. Niedre earned his PhD in Medical Biophysics from the University of Toronto (2005) and completed a postdoctoral fellowship at Harvard Medical School/Massachusetts General Hospital. His work has been supported by grants from the National Cancer Institute, NIH, and other agencies, including a $2.7M NIH grant for studying metastasis mechanisms. His research interests emphasize ultrafast time-domain imaging, image reconstruction, and biomedical signal processing. Notable projects include developing instruments for real-time detection of fluorescently labeled cells and non-invasive monitoring of cancer progression. His lab’s advancements aim to translate these technologies into clinical applications for early cancer detection and personalized medicine. Awards: COE Distinguished Professor (2015), Søren Buus Outstanding Research Award, Massachusetts Life Sciences Center New Investigator Award Grants: NIH/NCI grants for in vivo flow cytometry and tumor cell monitoring Lab Team: Includes students like Jane Lee, Amber Williams, and Fernando Ivich, focusing on sensor design and signal processing Dr. Niedre’s work bridges engineering and medicine, with a vision to create low-cost, accessible medical devices for global health challenges, as highlighted in student-driven projects and co-op experiences.

• Hematology
• Oncology
• Genomics
• +5 more

Ross L. Levine is a Professor of Medicine at Weill Cornell Medical College, specializing in hematologic malignancies with a focus on acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPNs). His research integrates genomics, epigenetics, and stem cell biology to unravel mechanisms driving clonal evolution and therapeutic resistance. Affiliation : Weill Cornell Medical College (2015–present) Research Themes : Mutation order in AML, epigenetic dysregulation, JAK-STAT pathway activation, sphingolipid metabolism in leukemia, and clonal hematopoiesis in aging/cardiovascular disease. Recent publications highlight his work on: 2024 ELN risk stratification for AML patients CRISPR screens identifying genotype-specific vulnerabilities Multiomic survival predictors in African American AML patients Senolytic CAR T cells for age-related metabolic dysfunction His studies span functional genomics, drug development, and clinical implementation of genomic profiling, with a strong emphasis on precision medicine applications in hematologic cancers.

Catherine RinaldiView profile

Researcher

• Flow Cytometry
• Mass Cytometry
• Cancer Immunotherapy
• +3 more

Catherine Rinaldi is a Senior Research Officer at the Centre for Microscopy, Characterisation & Analysis (CMCA) in The University of Western Australia . Her work focuses on flow cytometry, cancer immunotherapy, and drug repurposing for fibrosis and oncological applications. Education: BSc (Hons), University of Western Australia PhD, University of Western Australia (2015), researching passive immunotherapy to prevent influenza Research Interests span flow cytometry, mass cytometry, single-cell analysis, and their applications in cancer biology and fibrotic disease. She specializes in multiplex cytometry assays and biosafety protocols. Recent Research Trends include: therapeutic inhibition in mesothelioma, chemotherapy-induced fibrosis mechanisms, and leveraging network analysis for drug repurposing in immunotherapy. Her work employs advanced cytometry platforms like BD FACSMelody and CyTOF. Scientific Grants include: Channel 7 Telethon Trust (2024): Spectral Flow Cytometer project leadership University of Western Australia (2020-2022): Tumour macrophage behavior in breast cancer She advises on flow cytometry training and instrument operation, supporting researchers with BD FACS systems, Luminex assays, and ALS CellCelector technologies.

• Light scattering
• Discrete dipole approximation (DDA)
• Biomedical optics
• +2 more

Euiwon Bae is a Senior Lecturer and Senior Research Scientist at the School of Mechanical Engineering, Purdue University. He holds a Ph.D. (2006) from Purdue University, an M.S. (2001) from KAIST, and a B.S. (1998) from Korea University. His research focuses on light scattering, biomedical optics, and food safety instrumentation. He leads the Applied Optics Laboratory and the Laser Diagnostics Laboratory, developing optical sensing technologies for bacterial detection and characterization. Affiliations: Purdue University Roles: Senior Lecturer, Senior Research Scientist Research interests include discrete dipole approximation (DDA), optical characterization of soot, and instrument development for food safety. Notable awards include a 2009 Burton D. Morgan Business Plan Competition finalist status and a 1997 US Army commendation medal. Advises student Nan Bai on Ph.D. research in bacterial colony analysis. Research Highlights Bae’s work spans optical biosensors for pathogen detection (e.g., Listeria, Salmonella) and advanced light scattering models. Recent innovations include smartphone-integrated diagnostics and LIBS-based food authentication systems. His lab integrates machine learning with optical sensing for rapid, label-free pathogen identification. Awards & Grants Burton D. Morgan Business Plan Competition Finalist (2009) KAIST Graduate Fellowship (1999–2001) US Army Commendation Medal (1997) Labs & Teams Leads the Applied Optics Laboratory and Laser Diagnostics Laboratory , collaborating with industry on food safety and biomedical optics projects.

• Bayesian Statistics
• Biostatistics
• Spatial Transcriptomics
• +5 more

Dr. Satwik Acharyya is an Assistant Professor at the University of Alabama at Birmingham (UAB) with primary appointments in the Department of Biostatistics (School of Public Health) and secondary affiliation in the Department of Biomedical Informatics and Data Science. Holding concurrent roles at UAB's Center for Clinical and Translational Science (CCTS) and O'Neal Comprehensive Cancer Center, he bridges statistical methodology with biomedical applications. PhD in Statistics from Texas A&M University (2020) Postdoctoral Fellow at University of Michigan-Ann Arbor Research Focus: Combines Bayesian statistics with translational medicine, specializing in: Bayesian Graphical and Hierarchical Modeling Variational Bayes and Non-standard Manifold Computation Spatial Transcriptomics and Single-Cell Omics Neuroimaging and Cancer Informatics Publication Trends: Recent work emphasizes spatial multi-omics integration, including novel tools like CAFE for flow cytometry analysis and SpaceX for spatial transcriptomics networks. Key methodologies address sample heterogeneity in genomic networks and covariance modeling for neuroimaging. Scientific Contributions: Notable awards include the 2025 UAB School of Public Health Pilot Award. He serves on multiple dissertation committees and actively participates in journals as reviewer.

Damien KingView profile

Assistant Professor

• Microfluidic Based Single Cell Analysis
• Microfluidic Cell Enrichment Techniques
• Process Analytical Technology for Upstream Processing in Biopharmaceutical Production and Bioprocessing
• +4 more

Dr. Damien King is an Assistant Professor at the School of Biotechnology, Dublin City University (DCU), since September 2022. He specializes in Bioprocess Engineering and develops microfluidic systems for single-cell applications in biopharma, diagnostics, and regenerative medicine. His career spans academia, industry, and entrepreneurship, including roles at the University of Limerick (UL), Stokes Bio Ltd., Life Technologies, and the Fraunhofer Project Centre at DCU. Education: BEng in Electronic Engineering (UL, 1997–2001) PhD in Optical Fibre Sensors and Artificial Neural Network Pattern Recognition (UL, 2001–2005) Dr. King’s research focuses on microfluidic platforms for single-cell analysis , organoids in cancer , and extracellular vesicles as diagnostics. He integrates biophotonic devices with process analytical technology to streamline biopharmaceutical workflows. His recent work emphasizes automation via lab-on-a-disc systems and cell enrichment techniques . His publications highlight advancements in microfluidics for biomedical applications , including optical detection systems and dissolvable valve automation. These studies span disciplines like biophysics , cell biology , and diagnostics , with subfields in lab-on-a-chip , biomarker discovery , and bioprocessing . Scientific Awards: DCU Professional Skills for Research Leaders Programme (2018) DCU Invent Commercialization Award (2022) Dr. King supervises PhD candidates such as Tom Erik Pedersen and Letizia Palanga. He has secured projects like uPAT (microfluidic process analysis) and Extracellular Vesicles Hydrogel Coatings (immunomodulatory implants). His patents include End-Point Optical System (2014) and Biological Detection System (2019).

Qiyin FangView profile

Professor

• Biomedical Engineering
• Optical Spectroscopy
• Medical Imaging
• +5 more

Dr. Qiyin Fang is a Professor of Engineering Physics at McMaster University and a Fellow of SPIE. He holds a BSc in Physics from Nankai University, and MSc/PhD in Biomedical Physics from East Carolina University. Prior to joining McMaster, he worked at Cedars-Sinai Medical Center in Los Angeles. His research focuses on developing optical spectroscopy and imaging systems for biomedical and environmental applications, including optical biopsy techniques, endoscope designs, photodynamic therapy, and smart home technologies for aging populations. Education: BSc Physics, Nankai University (1995) MSc Applied Physics, East Carolina University (1998) PhD Biomedical Physics, East Carolina University (2002) Research Interests: Multimodality optical systems for clinical diagnosis Biomedical imaging technologies (e.g., FLIM, endoscopy) Optical sensors for environmental monitoring Smart health systems for aging-in-place Ultrafast laser applications in medical implants Awards & Grants: Fellow of SPIE (Society for Optics and Photonics) Early Researcher’s Award (Province of Ontario) Labs & Teams: Leads the Biophotonics Lab at McMaster, collaborating on projects such as the Centre for Advanced Light Microscopy and smart home aging technologies. His work integrates engineering, physics, and clinical applications to address unmet healthcare needs.

Hsuan ChenView profile

Assistant Professor

• Ornamental Plant Breeding
• Cytogenetics
• Ploidy Manipulation
• +2 more

Hsuan Chen is Assistant Professor in the Department of Horticultural Science at NC State University, specializing in ornamental plant breeding through cytogenetics, ploidy manipulation, and molecular techniques. His research develops novel ornamental cultivars with enhanced traits using genomic tools and ploidy engineering applied to crops like hemp, hibiscus, and redbud. Education includes a PhD in Plant Breeding and Genetics from Oregon State University (2018), MS in Agronomy from National Taiwan University, and BS in Life Sciences from National University of Kaohsiung. Research integrates conventional breeding with flow cytometry, interspecific hybridization, and marker-assisted selection. Focus areas include genome doubling techniques, nutrient diagnostics using data science, and phenotypic selection for ornamental traits. Industry experience as Research Scientist at Oregon CBD informs practical breeding applications. Recent publications emphasize ploidy manipulation (cannabis, peanut wild relatives, spicebush), data-driven nutrient management, and predictive phenotyping. Articles frequently feature cytogenetic validation and statistical approaches to breeding challenges. Leads the Chen Lab developing ornamental breeding technologies and provides campus-wide expertise in cytogenetic techniques including chromosome squashes and ploidy confirmation.

Esa PitkänenView profile

Adjunct Professor

• Machine Learning
• Biomedicine
• Computational Biology
• +4 more

Esa Pitkänen is a Senior Researcher at the Institute for Molecular Medicine Finland (FIMM) and holds an Adjunct Professorship in the Department of Computer Science at the University of Helsinki. He is actively involved in the Doctoral Programme in Integrative Life Science, supervising doctoral research. His work bridges computational methods with biomedical applications, focusing on machine learning, genomics, and systems biology. His research interests include developing predictive models using neural networks for medical imaging (e.g., amyloid PET analysis), genomic studies of cancer subtypes (e.g., AML and B-cell lymphomas), and bioinformatics tools for variant discovery. He leads projects funded by the Juselius Foundation and the Academy of Finland, emphasizing personalized medicine and translational oncology. Pitkänen’s recent publications highlight advancements in automated medical coding via deep learning, genomic insights into iron metabolism disorders, and single-cell transcriptomic approaches to cancer therapy optimization. His contributions span computational biology, precision medicine, and multi-omics integration in healthcare. He manages the Meilahti Biodata facility and has supervised doctoral student Kaasinen. His work often involves collaborations across disciplines, addressing challenges in liquid biopsy, mutational signatures, and AI-driven diagnostics.

Angela NicoliView profile

Research Fellow

• Neuroscience
• Molecular Biology
• Biochemistry
• +3 more

Dr. Angela Nicoli is a Postdoctoral Fellow at the Biology Teaching & Learning Centre , part of the School of Medicine and Psychology at the Australian National University (ANU). Her work focuses on synaptic mechanisms and neurotransmitter dynamics within the Division of Neuroscience (Eccles Institute of Neuroscience). Education: B.Sc. (Hons) PhD Research Interests include: Neurotransmitter transport systems Amino acid metabolism in synaptic function Glutamate-glutamine cycle regulation CNS excitatory synapse physiology Advanced immunophenotyping techniques Publications highlight her work on glutamine transporters like NTT4 (SLC6A17) and their role in maintaining synaptic glutamate homeostasis. Her research leverages spectral flow cytometry and multidisciplinary approaches to study neural mechanisms.

Karthik Subramanian KrishnanView profile

Research Fellow

• Epilepsy
• Calcium Signaling
• TRP Channels
• +3 more

Karthik Subramanian Krishnan is a Postdoctoral Fellow at the Division of Neuroscience (Eccles Institute of Neuroscience) within the John Curtin School of Medical Research at the Australian National University. His research focuses on elucidating the role of TRP Ankyrin 1 (TRPA1) channels in epilepsy pathogenesis and neuronal calcium dysregulation. Education: B.Pharm MNeuro (Advanced) Research Interests: Dr. Krishnan investigates epilepsy mechanisms with emphasis on TRPA1-mediated calcium influx in cortical neurons. His work addresses the critical gap in understanding why conventional calcium channel inhibitors fail in epilepsy treatment, exploring TRP channels as novel therapeutic targets. Research spans neurological disorder pathophysiology , ion channel signaling , neuropharmacology , and translational neuroscience , with direct implications for developing targeted epilepsy therapies. Laboratory Affiliation: Member of The Kheradpezhouh Group - Calcium Signalling at the Eccles Institute of Neuroscience, where he utilizes spectral flow cytometry and neuronal activity modeling to study seizure mechanisms.

Avinash UpadhyaView profile

Research Fellow

• Genomics
• Cancer Research
• Computational Biology
• +3 more

Avinash Upadhya is a Research Fellow affiliated with the John Curtin School of Medical Research at the Australian National University (ANU). His work is associated with multidisciplinary medical research, focusing on areas such as genomics, cancer, and biomedical sciences. His current affiliations include the Division of Genome Sciences and Cancer and the Centre for Computational Biomedical Sciences as a visitor. He is part of the Lee Group - Optical Biofluidic Imaging Group , indicating a specialization in advanced imaging techniques for biomedical applications. Contact information includes the email address u5163163@anu.edu.au . Research areas linked to his role at JCSMR emphasize translational medical research, aiming to address diseases like cancer, diabetes, and metabolic disorders through innovative methodologies such as spectral flow cytometry and computational analysis.

Thomas HenkelView profile

Researcher

• Microfluidics
• Biotechnology
• Biophotonics
• +3 more

Dr. Thomas Henkel is a Researcher at the Leibniz Institute of Photonic Technology, leading the Microfluidics Research Group since 2002. His work focuses on microsystem technology for biotechnological applications, particularly in biophotonics, environmental monitoring, and drug discovery. Research Interests: Dr. Henkel's research spans Microfluidics and Lab-on-a-chip systems Imaging flow cytometry (IFC) and tomographic IFC (tIFC) Bioparticle characterization Plasmonic sensing Automated screening platforms Environmental safety applications Publication Trends: Over the past five years, Dr. Henkel has developed microfluidic systems for high-throughput bioparticle analysis, including astaxanthin-producing Haematococcus pluvialis monitoring, hepatitis B drug screening, and Legionella detection. His work combines multispectral imaging, machine learning, and innovative fluid dynamics to enable label-free cell sorting and real-time process monitoring. Labs & Teams: As group leader, he collaborates with interdisciplinary teams at Leibniz-IPHT, integrating photonic technology, materials science, and biotechnology to advance microfluidic applications in medical and environmental fields.

• Neuroscience
• Immunology
• Computational Biology
• +1 more

Shiva Soltani Dehnavi is a Postdoctoral Research Fellow at the John Curtin School of Medical Research (JCSMR) , part of the Australian National University. Their work focuses on multidisciplinary translational medical research, particularly in neuroscience, with affiliations to the Division of Neuroscience (Eccles Institute of Neuroscience) . Contact: shiva.soltani@anu.edu.au JCSMR researchers, including Shiva, contribute to advancements in fields such as immunology, cancer, genomics, and metabolic disorders. Their research likely intersects with computational biology given the school’s postgraduate programs in this area. Shiva’s recent publication on Advanced immunophenotyping of lymphocyte and monocyte subsets highlights their work in developing novel spectral flow cytometry techniques to analyze immune cell populations in healthy individuals, potentially informing studies on diseases like diabetes and rheumatoid arthritis. Located at JCSMR, Building 131, Garran Road, Acton, 2601, Shiva collaborates within a research environment dedicated to transforming healthcare through cutting-edge discoveries.

Srinivasan SundararajView profile

Research Fellow

• Immunology
• Cancer
• Genomics
• +4 more

Dr. Srinivasan Sundararaj serves as a Postdoctoral Fellow at the John Curtin School of Medical Research (JCSMR), Australian National University, contributing to Australia's premier medical research ecosystem. Based in Room 2.077.4, he operates within JCSMR's multidisciplinary framework focused on translational breakthroughs. His research spans JCSMR's core domains including Immunology , Cancer Biology , Genomic Medicine , and Neuroscience , with direct relevance to metabolic disorders and infectious disease mechanisms. This work aligns with institutional priorities targeting conditions like diabetes, rheumatoid arthritis, and vision impairment through cutting-edge laboratory approaches. As a Research Fellow, Dr. Sundararaj participates in JCSMR's collaborative infrastructure while utilizing advanced facilities for spectral flow cytometry and genomic analysis. His position supports the school's mission to transform healthcare through discoveries that bridge basic science and clinical applications, with active engagement in research groups tackling Australia's most pressing health challenges.