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Professor Matthias Mann is a world-leading scientist serving as Director of the Proteomics and Signal Transduction department at the Max Planck Institute of Biochemistry in Martinsried, Germany, and Director of the Proteomics department at the Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Denmark. With an h-index exceeding 277 and over 350,000 citations, he is recognized as the highest cited German researcher and one of the most influential scientists globally in proteomics. His educational background includes: Ph.D. in Chemical Engineering from Yale University (1988) Master's Degree in Physics from Georg August University Göttingen (1984) Bachelor's of Arts in Mathematics from Georg August University Göttingen (1982) Professor Mann's research focuses on advancing mass spectrometry-based proteomics to understand biological systems at the protein level. His work spans technological developments in mass spectrometry, bioinformatics and computational analysis, signal transduction and posttranslational modifications, and clinical proteomics applications for disease diagnosis and treatment. The Mann lab has pioneered groundbreaking methods like SILAC for quantitative proteomics and MaxQuant for proteome data analysis. Their vision is to translate proteomics knowledge into clinical practice for predictive, diagnostic, and preventive medicine, with recent work focusing on AI-guided platforms for analyzing proteomes from minimal tissue samples. Analysis of Professor Mann's recent publications reveals a strong trend toward clinical applications of proteomics, particularly in cancer research, metabolic diseases, and neurodegenerative disorders. His work increasingly integrates spatial proteomics, single-cell resolution techniques, and artificial intelligence approaches to uncover disease mechanisms and identify potential biomarkers, with a clear shift from basic technology development toward direct clinical applications and personalized medicine. Professor Mann has received numerous prestigious awards throughout his career: 2025: Elected member of the American National Academy of Sciences 2024: Dr. H.P. Heineken Award for Biochemistry and Biophysics 2023: Otto Warburg Medal 2019: Nominated member of the Bavarian Academy of Sciences 2013: Elected member of Leopoldina German National Academy of Sciences 2012: Körber European Science Award, Louis-Jeantet Foundation Prize for Medicine, Ernst Schering Prize, and Leibniz Prize Professor Mann leads a highly collaborative research team involved in multiple international networks including the Bill & Melinda Gates Foundation, Michael J. Fox Foundation for Parkinson's Research, CLINSPECT-M, and Munich Heart Alliance. His lab has mentored numerous successful researchers, with several former postdocs receiving prestigious ERC Starting Grants. The Mann group has developed innovative clinical proteomics pipelines for analyzing archived tissue specimens and body fluids, aiming to identify protein markers for early detection of diseases such as diabetes and cancer. The Mann lab operates across two major research centers with state-of-the-art mass spectrometry facilities. Their Clinical Knowledge Graph platform integrates multi-omics data with extensive metadata, creating an ecosystem for machine learning applications in proteomics. Current research focuses on developing highly sensitive methods that can profile thousands of proteins from minimal cell samples, enabling the identification of critical disease-related proteins and supporting the development of individualized therapies.

• Mass Spectrometry
• Proteomics
• Systems Biology
• +6 more

Dr. Sabine Krabbe is a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Bonn, Germany, where she leads research on neural circuit mechanisms underlying adaptive learning and state-dependent decision-making. Her work integrates neuroscience, molecular biology, and behavioral approaches to understand how internal states influence behavior and how these processes are disrupted in neurological disorders. Dr. Krabbe's research focuses on the interactions between midbrain circuits of the substantia nigra and ventral tegmental area with their output structures such as the striatum and amygdala. She investigates how these networks integrate internal states with environmental cues to produce appropriate behavioral responses. Her laboratory employs state-of-the-art techniques including deep-brain calcium imaging at single-cell resolution in mice, opto- and pharmacogenetic manipulations, anatomical tracings, and molecular approaches to characterize neural circuit elements in detail. Her recent publications reveal significant insights into amygdala interneuron plasticity during fear learning, brain-wide representational drift in memory consolidation, and the molecular mechanisms underlying Parkinson's disease progression. Her work demonstrates how activity patterns within specific neural circuits change in early stages of neurodegenerative diseases and how this dysfunction contributes to cognitive deficits and emotional disturbances. Dr. Krabbe is actively involved in the neuroscience community, organizing the BonnBrain Conference 2026 and sharing research through social media platforms. She has established herself as an emerging leader in the field of systems neuroscience with a particular focus on the neural basis of emotional states and decision-making processes.

• Neural circuit mechanisms
• Adaptive learning
• State-dependent decision-making
• +4 more

Prof. Dr. Oliver Krüger is a behavioral ecologist and evolutionary biologist at Bielefeld University 's Faculty of Biology , where he leads the Department of Animal Behaviour since 2013. His research spans avian and marine mammal systems, focusing on life history strategies, parasite-host interactions, and environmental adaptation. Education: Biology studies at Bielefeld University (1994-1996) MSc in Oxford (1996-1997) PhD at Bielefeld University with Fritz Trillmich and Jan Lindström (1998-2000) Research Themes: Behavioral ecology, evolutionary biology, and population dynamics across tropical and temperate ecosystems. Key projects include NC³ (Niche Choice/Construction) and studies on Galápagos sea lions, common buzzards, and pinniped species. Scientific Leadership: Spokesperson, SFB TRR 212 "NC³" (2018-2025) Advisory Board member: German Ornithologists Union, IUCN SSC pinniped group, German Primate Centre Peer review roles: Humboldt Foundation, DFG, HFSP, NSF Awards: Leopoldina Prize (2001) Niko Tinbergen Award (2008) DFG Heisenberg Professorship (2010-2015)

• Behavioral Ecology
• Evolutionary Biology
• Population Ecology
• +11 more

Nikolaus Rajewsky is a leading Professor at the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin , where he founded and directs the Berlin Institute for Medical Systems Biology (BIMSB) . His lab integrates experimental (biochemistry, molecular biology) and computational (bioinformatics, physics) approaches to study RNA regulation in gene expression , with applications to developmental biology, regeneration, neurodegenerative diseases, and cancer . Using model systems like C. elegans , planaria, and human brain organoids, his team pioneers cutting-edge methods such as MirDeep , DistMap , and FLAM-seq for RNA analysis. His research focuses on single-cell transcriptomics , spatial RNA sequencing , and circular RNA (circRNA) regulation , revealing novel roles for circRNAs like CDR1as in neuropsychiatric disorders. Recent work includes 3D tumor microenvironment mapping and computational modeling of RNA metabolism in diseases. Scientific Awards : Gottfried Wilhelm Leibniz Prize (2012) EMBO Membership (2010) Honorary PhD, Sapienza University of Rome (2014) Berlin Science Award (2009) His team's recent articles highlight breakthroughs in 3D spatial transcriptomics , circRNA degradation mechanisms , and mitochondrial disease modeling using human brain organoids. The lab actively collaborates with clinical partners across Charité and European institutions, driving the LifeTime initiative for cell-based interceptive medicine.

• RNA Biology
• Gene Regulation
• Single-Cell Transcriptomics
• +6 more

Marco Cuturi is a Research Scientist at Apple ML Research in Paris and Professor of Statistics at CREST-ENSAE, Institut Polytechnique de Paris. His work bridges machine learning , optimal transport , and optimization , with applications in time-series analysis , kernels , and multiresolution methods . He has held academic roles at Kyoto University and Princeton University, and previously worked in the financial industry. Research Interests: Optimal transport theory and computational methods Kernel design for structured data and histograms Time-series alignment and soft-DTW Entropic regularization in optimization Applications to computer vision and genomics Teaching: Cuturi has taught courses on linear optimization at Princeton, geometric methods in machine learning at Kyoto, and scientific English. He has also organized machine learning summer schools in Kyoto, Les Houches, and other international venues. Recent Trends: His 2024-2025 publications focus on entropic optimal transport solvers, disentangled representation learning via Gromov-Monge gaps, and applications to text-to-image diffusion models. Collaborative work with institutions like Google Research, MIT, and University of Tokyo highlights his interdisciplinary impact.

• Machine Learning
• Optimal Transport
• Optimization
• +4 more

Prof. Dr. Kirsten Jung is a faculty member at the Department of Microbiology , Faculty of Biology , Ludwig Maximilian University of Munich . Her research focuses on bacterial signal transduction, stress response mechanisms, and systems biology approaches to understand microbial regulatory networks. Key research areas include stress-dependent gene expression in bacterial populations Structural and functional analysis of membrane-integrated receptors Metabolism-based chemical communication in bacteria Integration of experimental and computational systems biology Recent publications highlight her lab's work on Escherichia coli epitranscriptomic modifications under heat stress, m 5 C rRNA dynamics, and the role of RNA methylation in host-pathogen interactions. Collaborative studies address bacterial acid stress responses and their implications for antibiotic tolerance. Her interdisciplinary work bridges microbiology with ecological studies, as evidenced by research on biodiversity conservation in forest and urban ecosystems. Publications also demonstrate expertise in advanced imaging techniques (e.g., arterial spin labeling for glioma analysis) and bioinformatics approaches. Current advisees include Gloria Gessinger and Tania P. Gonzalez-Terrazas . She can be contacted at jung@lmu.de .

• Bacterial Signal Transduction
• Stress Response Mechanisms
• Membrane Protein Structure-Function Analysis
• +3 more

Dr. Eric T. Reifenstein is a neuroscience researcher at Humboldt-Universität zu Berlin's Faculty of Life Sciences, Institute of Biology, specializing in neural mechanisms of spatial navigation and memory. As a key contributor to SFB 1315 (Entorhinal Cortex as Interface between Memory and Space), his work bridges computational modeling and human electrophysiology. His research focuses on egocentric spatial mapping and sequence learning mechanisms , with particular expertise in human single-neuron recordings during virtual navigation tasks. Reifenstein investigates how the brain encodes self-centered spatial representations and how synaptic learning rules enable temporal sequence memorization. His publication trends reveal a strong emphasis on translational neuroscience , connecting rodent studies to human cognition through innovative virtual reality paradigms. Key methodological approaches include single-neuron recordings, computational modeling of neural networks, and behavioral analysis of spatial memory. Scientific contributions include: Identification of egocentric bearing cells in human parahippocampal cortex Mathematical analysis of phase precession in sequence learning Vectorial representation models of egocentric space Reifenstein actively collaborates with leading researchers including Prof. Richard Kempter and Joshua Jacobs, contributing to major neuroscience journals like Neuron and eLife. His work has implications for understanding memory disorders and developing neural prosthetics.

• Neural coding
• Spatial navigation
• Memory systems
• +4 more

Richard Kempter is a Full Professor at the Humboldt-Universität zu Berlin, where he leads the Theoretical Neuroscience research group within the Institute for Theoretical Biology, Department of Biology. His research focuses on the neural basis of learning and memory through computational and mathematical modeling of synapses, neurons, and neural networks. He is affiliated with several major research centers including the Bernstein Center for Computational Neuroscience, the Einstein Center for Neurosciences Berlin, and the CRC 1315 Memory Consolidation. Professor Kempter's research interests span theoretical and computational neuroscience with a particular focus on the neural mechanisms underlying learning and memory. His work employs biophysical modeling and mathematical analysis to study synaptic short- and long-term plasticity, the dynamics of single neurons, and the interaction of neurons in recurrently coupled networks. A key aspect of his research investigates how neural systems maintain a balance between learning susceptibility and stability against pathological activity patterns, with model systems including the hippocampus and early auditory system. His research group has made significant contributions to understanding hippocampal sharp wave-ripple events, phase precession in spatial navigation, auditory processing in barn owls, and memory consolidation mechanisms. The group's work combines theoretical approaches with computer simulations to unravel the computational principles of neural circuits, showing particular interest in how neural tissue remains susceptible to learning while maintaining robust stability against pathological activity patterns. Scholarship of the State of Bavaria (03/1994-12/1995) Emmy Noether Fellowship Part I (09/1999-08/2001), funded by the Deutsche Forschungsgemeinschaft Emmy Noether Fellowship Part II (01/2003-09/2008) Guest Professor , HU Berlin, Department of Biology (10/2008-03/2010) Professor Kempter has advised numerous PhD and Master's students throughout his career, with many continuing in neuroscience research. His group maintains strong connections with experimental laboratories to bridge computational models with empirical findings, particularly in hippocampal function and auditory processing. The Theoretical Neuroscience Lab participates in collaborative projects investigating memory consolidation and neural coding principles, contributing significantly to our understanding of how neural circuits implement computational principles underlying learning and memory.

• Theoretical Neuroscience
• Computational Neuroscience
• Neural basis of learning and memory
• +7 more

Dr. Karol Nowicki-Osuch is a Group Leader at the German Cancer Research Center (DKFZ) , leading a research group focused on tumorigenesis and molecular cancer prevention. His work emphasizes understanding early stages of gastrointestinal tumor development using multimodal techniques like single-cell RNA sequencing, organoid models, and spatial transcriptomics. Key research areas include the molecular mechanisms underlying Barrett's esophagus, gastric intestinal metaplasia, and the transition to adenocarcinoma. Collaborations span institutions in Germany, Poland, the UK, and the US. His team investigates how normal epithelial cells lose molecular identity and progress to precancerous states. Notable achievements include demonstrating that esophageal adenocarcinoma originates from gastric tissue and identifying novel mutational signatures using the mutREAD method. Current projects aim to develop early cancer detection strategies and in vivo models of tumor progression. Dr. Nowicki-Osuch supervises PhD students and employs cutting-edge technologies such as spatial transcriptomics and organoid platforms. His lab integrates computational biology with experimental approaches to address gaps in understanding clonal evolution and somatic mutations in gastroesophageal cancers.

• Cancer Biology
• Molecular Oncology
• Gastrointestinal Cancers
• +3 more

Ewa Szczurek is a Professor at the University of Warsaw's Faculty of Mathematics, Informatics and Mechanics and Co-director of the Institute for AI for Health, leading joint labs at Helmholtz Munich and the University of Warsaw. Education: Master degree in Computer Science from Uppsala University, Sweden (2005) Master degree in Computer Science from University of Warsaw, Poland (2006) Doctoral degree from Max Planck Institute for Molecular Genetics, Berlin (2011) Postdoctoral fellowship at ETH Zurich, Switzerland (2011) Habilitation at University of Warsaw, Poland (2020) Visiting associate professor at Northwestern University, USA (2023) Research Focus: Her work centers on probabilistic graphical models and deep generative models applied to computational medicine, with emphasis on oncology (tumor microenvironment modeling and evolution), pulmonology, and AI-driven antimicrobial peptide design to combat antibiotic resistance. She develops specialized deep learning frameworks for spatial transcriptomics analysis, tumor evolution reconstruction, and synthetic antimicrobial compound generation. Publication Trends: Recent publications (2022-2023) demonstrate consistent innovation in AI-driven biomedical solutions, bridging machine learning with oncology and infectious disease research. Her work shows increasing focus on generative models for drug design and spatial data analysis, with strong industry-academia collaborations (e.g., Merck, IMMUcan consortium). Awards: ERC Consolidator Grant (2023) for DOG-AMP project Scientific and didactic award from Rector of University of Warsaw ETH Zurich and IMPRS fellowship awards Grants & Leadership: Leads the ERC Consolidator Grant project DOG-AMP for antimicrobial peptide design. Serves as Associate Editor for Genome Biology and participates in program committees for ISMB and RECOMB-CCB conferences. Collaborates with international consortia including IMMUcan and Merck's Oncology Bioinformatics department. Labs & Networks: Co-directs AI for Health Institute with joint labs at Helmholtz Munich and University of Warsaw. Active in ELLIS (pan-European AI network) and Polish Bioinformatics Society, driving interdisciplinary research at the AI-medicine interface.

• Artificial Intelligence
• Probabilistic Graphical Models
• Deep Generative Models
• +4 more

Marios Georgakis is a clinician-scientist and Junior Group Leader at the Institute for Stroke and Dementia Research (ISD) at LMU Munich. He also holds a Visiting Scientist position at the Broad Institute of MIT and Harvard. His research focuses on leveraging multi-omics data and causal inference methods (e.g., Mendelian randomization) to discover drug targets for atherosclerosis, develop personalized risk stratification tools for cerebrovascular disease, and identify in vivo biomarkers of disease activity. His work bridges human genetics, molecular biology, and clinical translation. Education : MD and PhD (Epidemiology) from the National and Kapodistrian University of Athens; doctoral studies in Systemic Neurosciences at LMU Munich. Honors : Emmy Noether Award (DFG), CHARGE Consortium Early Career Achievement Award, Hertie Network Fellowship, and multiple scholarships/fellowships. Research Themes : Drug target discovery for cardiovascular disease via multiomics integration Molecular phenotyping of atherosclerosis using single-cell RNA-seq and spatial transcriptomics Development of AI-driven tools for vascular imaging and aging Genetic studies of inflammation, cytokines, and stroke subtypes Causal inference in vascular risk prediction and post-stroke outcomes Recent Article Trends : His team's publications (2024-2020) emphasize: Proteogenomic and genetic studies of atherosclerosis Cytokine signaling pathways (e.g., IL-6, CCL2/CCR2) Polygenic and genomic risk scores for stroke Multi-omics biomarkers in cerebrovascular disease Clinical translation of Mendelian randomization findings Meta-analyses of population-based data Scientific Awards : Emmy Noether Group Leader Award (DFG, 2023) CHARGE Consortium Early Career Achievement (2023) Hertie Network Fellowship (2023) Walter-Benjamin Postdoctoral Fellowship (2021-2022) Team Leadership : Georgakis mentors multiple PhD students and postdocs in his lab. His group collaborates with vascular surgeons, neurologists, and computational biologists. Current projects include the AtherOMICS biobank and AI-driven vascular phenotyping tools.

• Cardiovascular Disease
• Stroke
• Atherosclerosis
• +8 more

Dr. Marios Georgakis is a Clinician-Scientist and Junior Group Leader at the Institute for Stroke and Dementia Research (ISD) at Ludwig-Maximilians-Universität München (LMU Munich). He also serves as a Visiting Scientist at the Broad Institute of MIT and Harvard and is completing his clinical residency in Neurology at LMU University Hospital. As Principal Investigator of the Georgakis Lab, he leads a research team focused on developing precision medicine approaches for cerebrovascular diseases. Education: Medical studies (M.D.): Medical School, National and Kapodistrian University of Athens, Greece (2009-2015) Master studies (M.Sc.): Molecular Physiology (Neurosciences), National and Kapodistrian University of Athens, Greece (2015-2017) Doctoral studies (D.Sc.) in Epidemiology, National and Kapodistrian University of Athens, Greece (2015-2019) Doctoral studies (Ph.D.) in Graduate School of Systemic Neurosciences (GSN), LMU Munich, Germany (2017-2020) Dr. Georgakis' research focuses on leveraging big data from epidemiological studies and human biobanks to develop precise and personalized preventive and therapeutic strategies for cerebrovascular diseases. His work spans biomedical neuroscience with particular emphasis on cerebrovascular disease, stroke, atherosclerosis, cerebral small vessel disease, multi-omics, data science, epidemiology, and population genetics. He employs innovative bioinformatic tools including genome-wide association studies, Mendelian randomization, multi-omics integration, single-cell transcriptomics, spatial transcriptomics, and machine learning to discover causal mechanisms, identify therapeutic targets, develop risk stratification tools, and create accurate biomarkers for cerebrovascular diseases. His laboratory has established the AtherOMICS biobank for human atherosclerotic plaque samples and developed computational pipelines for big data analyses. Recent publication trends show a strong focus on genetic architecture of stroke, inflammatory pathways in cerebrovascular disease, and development of polygenic risk scores for clinical application. Scientific Awards: Emmy Noether Independent Group Leader Award, German Research Foundation (DFG), 2023 Early Career Achievement Award, CHARGE Consortium, 2023 Fellow of the Hertie Network of Excellence in Clinical Neuroscience, 2023 Clinician-Scientist Fellow of the Excellence Munich Cluster for Systems Neurology (SyNergy), 2023 Walter-Benjamin Fellowship for postdoctoral research by German Research Foundation (DFG), 2021-2022 Dr. Georgakis actively mentors a diverse team of 12 current students and postdocs including PhD students, MD students, and clinician scientists, with several alumni who have completed their training in his lab. His research is supported by multiple grants including the Emmy Noether program from the German Research Foundation, focusing on multi-omics characterization of immune mechanisms driving human atheroprogression, dissecting cerebrovascular atherosclerosis with population genetics, and developing personalized biomarkers using deep learning. The Georgakis Lab operates two main research platforms: the AtherOMICS Biobank for human atherosclerotic plaque samples and the Big Data Lab for computational analyses. These platforms enable his team to conduct deep phenotyping of human atherosclerosis, develop in vivo diagnostics, discover therapeutic targets, and create personalized diagnostic and risk prediction tools for cardiovascular diseases.

• Biomedical Neuroscience
• Cerebrovascular Disease
• Stroke
• +7 more

Mathias Munschauer leads the Department of Molecular Virology at Heidelberg University's Faculty of Medicine, within the Center for Infectious Diseases. His research group focuses on unraveling RNA regulatory mechanisms that govern viral infection outcomes, with emphasis on HCV, HBV, and Dengue virus. His research interests lie at the intersection of RNA biology and virology, particularly in understanding how viral RNA molecules interact with host cell components. The lab employs cutting-edge methodologies including RAP-MS and SHIFTR for RNA interactomics, integrated with functional genomics, single-cell transcriptomics, and AI-driven analysis of high-dimensional data. This systems-level approach enables the identification of host factors and regulatory pathways critical for viral replication and immune evasion. The recent publications highlight a strong trend toward spatially and temporally resolved analysis of RNA-protein interactions across diverse RNA viruses. There is a consistent focus on developing and applying innovative technologies to map host-virus interfaces, with applications in identifying antiviral targets and understanding infection mechanisms. The work spans molecular, cellular, and systems biology, with increasing integration of computational and machine learning approaches. Systems virology RNA-protein interactomics Host-pathogen interactions CRISPR screening Single-cell analysis Antiviral strategies Dr. Munschauer mentors a research team and contributes to the doctoral program in Infectious Diseases. His lab develops and shares novel reagents and methods, fostering collaborative science. While specific grants are not listed, the technological sophistication suggests substantial funding support. The lab operates within a vibrant research environment alongside other virology groups such as AG Bartenschlager and AG Ruggieri. The Munschauer Lab is part of a larger virology and infectious disease research ecosystem at Heidelberg University, collaborating across disciplines to advance understanding of viral pathogenesis. The team actively develops and applies innovative tools for RNA-centric discovery, positioning the group at the forefront of molecular virology.

• Molecular Virology
• RNA Biology
• Host-Pathogen Interactions
• +7 more

Prof. Dr. Felix Jonas is an Assistant Professor of Biochemistry at the School of Science, Constructor University Bremen, Germany. He leads research on the biochemistry of gene regulation , focusing on molecular mechanisms governing transcription factor function and chromatin dynamics in Saccharomyces cerevisiae . His work integrates CRISPR-Cas9, Next-Generation Sequencing, and computational data analysis. Education: B.Sc. in Molecular Life Sciences (University of Luebeck), M.Sc. in Biology: Cell Biology (ETH Zurich), Ph.D. in Bioengineering (Imperial College London) Work Experience: Postdoc/Senior Postdoc at Weizmann Institute of Science (2017-22), Visiting Student at Weizmann Institute (2015-16), International Program Associate at RIKEN (2011) Teaching: General Biochemistry (CH-100-B), Introduction to Bioinformatics (JTMS-10), Current Topics in Life Sciences (CA-BCCB-801), Advanced Biochemistry II - Molecular Genetics (CO-403-A) His research explores transcription factor target search , histone dynamics , and chromatin structure-function relationships . Recent publications highlight discoveries in nucleosome replacement, protein disorder grammar, and histone acetylation impacts on replication. Articles emphasize interdisciplinary approaches to eukaryotic gene regulation and systems biology. Visit his lab’s PhD recruitment page or watch his Fragile Nucleosome Talk for deeper insights into his work.

• Biochemistry
• Gene Regulation
• Transcription Factors
• +4 more

Hannah Spitzer is a Research Group Leader at the Institute for Stroke and Dementia Research (ISD) at Ludwig Maximilian University of Munich and an associated Research Group Leader at Helmholtz Munich's Computational Health Center. She leads the Spitzer Lab, focusing on computational analysis of multimodal brain datasets to advance understanding of neurovascular and neurodegenerative diseases. Her educational background includes: PhD in Computer Science from Heinrich-Heine University Düsseldorf and Research Center Jülich (2015-2020) Master's in Computer Science from RWTH Aachen (2013-2015) Bachelor's in Computer Science from RWTH Aachen (2009-2013) Dr. Spitzer's research integrates computational biology and machine learning to decode brain complexity, with emphasis on spatial omics analysis , interpretable image representation learning , and cross-modal data integration . Her group develops tools like squidpy and campa for spatial omics while applying graph neural networks to epilepsy lesion detection through the international MELD project, prioritizing biological interpretability in AI models. Recent publications reveal strong trends in leveraging graph neural networks for subtle brain lesion detection and creating computational frameworks for spatial omics integration. Her work consistently bridges advanced machine learning with clinical neuroscience to uncover disease mechanisms in neurodegeneration and vascular disorders. Dr. Spitzer actively mentors students including current PhD candidate Beatrice Guastella and alumni Deniz Fettahoglu (MSc) and Katia Berr (PhD). Her lab operates through major collaborations including the MELD epilepsy consortium and Helmholtz Imaging Project, with funding supporting computational pipeline development for small-vessel disease prediction and multimodal brain atlasing. The Spitzer Lab comprises postdoc Wasim Aftab and PhD student Beatrice Guastella, working on computational pipelines that integrate histology, spatial omics, and neuroimaging data to decode brain disease mechanisms through interpretable AI approaches.

• Computational Biology
• Machine Learning
• Spatial Omics
• +4 more