James WilmottView profile
Research Fellow
James Wilmott is an NHMRC Investigator Fellow and Research Fellow at the Melanoma Institute Australia, affiliated with the University of Sydney's Charles Perkins Centre. His work focuses on translational research integrating clinicopathology, genomics, and immunology to improve melanoma diagnosis, prognosis, and immunotherapy personalization. He leads major programs like the Personalised Immunotherapy Program (PIPdx), funded by the Cancer Institute NSW ($3.7M, 2022-2026), and collaborates internationally on projects studying drug resistance mechanisms and rare melanoma subtypes. Education and affiliations include membership in the International Cancer Genome Consortium and leadership roles in genomics-focused research networks. His research has led to landmark studies on melanoma genomics, including a Nature paper and multiple Nature Communications studies on 570 melanoma genomes. Research interests center on personalized therapies, high-dimensional spatial pathology, and understanding tumor microenvironment dynamics. Awards include the 2021 Young Researcher of the Year (Society of Melanoma Research) and multiple NSW Premier's Awards for Translational Cancer Research. Key grants include the MRA Team Science Award ($1.4M, 2020-2023) for studying in-transit melanoma therapies. Collaborators include institutions like the Garvan Institute, QIMR Berghofer, and international consortia. Labs/teams: Principal investigator of the Melanoma Institute Australia's PIPdx program and leader of the genomics and biomarkers theme in the Centre of Research Excellence in Melanoma.





