Samuel WallView profile
Research Professor
Samuel Wall serves as Chief Research Scientist and Research Professor in the Department of Computational Physiology at Simula Research Laboratory. His work focuses on developing computational models to understand cardiac electromechanics, with particular emphasis on stem cell-derived cardiomyocytes and personalized heart modeling approaches. His research interests span computational cardiac physiology, mechano-electric feedback mechanisms, stem cell-derived cardiomyocyte modeling, and drug response prediction. Wall's work integrates advanced computational methods with experimental cardiac physiology to create in-silico tools for evaluating cardiac function, tissue engineering applications, and drug effects. His research has significant implications for understanding arrhythmia mechanisms, cardiac remodeling, and developing more accurate preclinical drug testing platforms. Analysis of Wall's recent publications reveals a strong trend toward integrating computational modeling with microphysiological systems, particularly using human-induced pluripotent stem cell-derived cardiomyocytes. His work increasingly focuses on creating in-silico augmented platforms that combine experimental measurements with computational analysis to improve drug response prediction and understand fundamental cardiac mechanisms. The research spans multiple scales from sub-cellular mechanics to whole-organ function. Wall maintains active collaborations with leading institutions in cardiac modeling and biomedical engineering. His work frequently appears in high-impact journals spanning computational science, physiology, and biomedical engineering fields.
