Stefan SemrauView profile
Associate Professor
Dr. Stefan Semrau is an Associate Professor at the Leiden Institute of Physics (LION) within the Faculty of Science at Leiden University . His research focuses on quantitative single-cell biology, particularly studying cell-fate decision-making using embryonic stem cells as a model system. Develops single-cell RNA-seq and single-molecule FISH methods Applies machine learning and mathematical modeling to decode stem cell differentiation Investigates interplay of epigenetics, cell cycle, and signaling molecules His work addresses both fundamental biological dynamics and applications in regenerative medicine and cancer stem cell eradication . Recent publications emphasize single-cell transcriptomics and gene fusion quantification . The Semrau Lab maintains collaborations across disciplines and develops tools like fuseFISH for cancer research. Scientific Awards FOM-Projectruimte Grant (2016) for stem cell dynamics research Advising & Collaborations Current advisees include PhD students studying retinoic acid-induced differentiation and lineage priming. The lab integrates computational and experimental approaches through partnerships with biotech and physics teams.






