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Jennifer RossView profile

Professor

• Biophysics
• Soft Matter Physics
• Biological Condensed Matter Physics
• +5 more

Jennifer Ross is a Professor of Physics and Associate Dean for Creativity, Scholarship, and Research at the College of Arts & Sciences of Syracuse University . As a biophysicist, she investigates how cells organize their interiors through self-assembly and active matter principles, focusing on the microtubule cytoskeleton and enzyme-driven systems using single-molecule imaging . Her research bridges fundamental physics with biological organization . Education: Ph.D. in Physics, University of California, Santa Barbara (2004) B.A. in Physics and Mathematics, Wellesley College (2000) Research Focus: Self-organization of cytoskeletal networks Active matter dynamics in biological systems Motor protein interactions and cargo transport Programming circadian materials via biomolecular systems Microtubule severing mechanisms Recent Article Trends: 2025 studies explore kinesin-driven cytoskeletal composites, urease-DNA origami engineering, and crosslinker-regulated network mechanics 2024-2023 work examines ionic strength effects on microtubules, programmable circadian materials, and motor-cargo dynamics Earlier studies analyze actin-microtubule composites, liquid crystal phase control, and severing enzyme mechanisms Scientific Awards: Fellow of the American Physical Society (APS) and American Association for the Advancement of Science (AAAS) Cottrell Scholar (2025) and STAR Award Margaret Oakley Dayhoff Award (Biophysical Society) Grants: Leads multiple NSF, Sloan Foundation, and Research Corporation grants for projects like "Energy and Entropy Sculpting" and "Explorations: SUPER-Tech SHIP" . Teaching: Offers courses in experimental physics, microscopy, and biophysics, including a globally adopted hands-on microscope-building curriculum. Lab: Heads the Bio-Active Matter Lab , studying how cells harness noisy systems for autonomous organization.

Sriram SubramaniamView profile

Professor

• cryo-electron microscopy
• structural biology
• drug-design
• +4 more

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Shasha ChongView profile

Assistant Professor

• Transcriptional Regulation
• Intrinsically Disordered Proteins
• Single-Molecule Biophysics
• +4 more

Shasha Chong is an Assistant Professor of Chemistry at the California Institute of Technology and a Ronald and JoAnne Willens Scholar. She earned her B.S. from the University of Science & Technology of China (2008) and Ph.D. from Harvard University (2014). Her research bridges chemistry, physics, and biology to investigate the molecular mechanisms of cellular processes, focusing on intrinsically disordered regions (IDRs) in transcription proteins. Research Focus: IDRs in transcriptional regulation, cancer biology, liquid-liquid phase separation, and single-molecule imaging techniques. Grants & Awards: CCE Innovation Award (2024), ALSF Innovation Grant, Mallinckrodt Research Grant, Margaret E. Early Medical Research Trust Grant. Collaborations: Caltech-City of Hope Biomedical Research Initiative Grant (2025). Teaching: Co-instructor for courses like Biochemistry Laboratory (Ch 11) and Advanced Topics in Biochemistry (BMB/Bi/Ch 174). Labs & Teams: Leads the Chong Laboratory at Caltech, focusing on interdisciplinary approaches combining single-molecule imaging, genome editing, and bioinformatics.

Vadim CherezovView profile

Professor

• Membrane Protein Structure and Function
• G Protein-Coupled Receptors (GPCRs)
• Lipid-Protein Interactions
• +3 more

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

Christoph SchmidtView profile

Professor

• Biophysics
• Cell Mechanics
• Microrheology
• +5 more

Christoph F. Schmidt is the Hertha Sponer Distinguished Professor of Physics at Duke University with cross-appointments in the Thomas Lord Department of Mechanical Engineering and Materials Science, Biology, and Biomedical Engineering. He serves as Co-Director of the Duke Materials Initiative and leads an active research program at the intersection of physics and biology. His educational background includes a D.R. from the Technical University of Munich (Germany) in 1988. Schmidt has established himself as a leading researcher in biophysics through decades of innovative work. Professor Schmidt's research spans multiple scales of biological organization, from single molecules to whole organisms. His lab investigates cellular mechanics using advanced techniques including optical trapping, atomic force microscopy, and microrheology. A significant innovation from his group involves single-walled carbon nanotubes for high-bandwidth intracellular tracking. Current research focuses on cardiomyocyte mechanics, Drosophila tissue dynamics, and computational analysis of complex biological systems. His work on motor proteins like Eg5 and ncd has provided fundamental insights into cellular division mechanics. His recent publications (2021-2025) demonstrate increasing integration of computational approaches with experimental biophysics, particularly in analyzing cardiac tissue mechanics and Drosophila sensory systems. The work shows progression from fundamental biophysical measurements toward applications in understanding disease mechanisms and biological function. Professor Schmidt teaches several courses including PHYSICS 995 (Graduate Training Internship), PHYSICS 493 (Research Independent Study), PHYSICS 415 (Biophysics II), PHYSICS 174 (Introduction to Frontiers of Biophysics), and BIOLOGY 425 (Biophysics II). He has successfully mentored numerous graduate students to completion, including recent PhD graduates Dr. Mingru Li and Dr. Xiaoxuan Jian. The Schmidt Lab, part of Duke's Physics Department and the Duke Soft Matter Center, maintains state-of-the-art equipment for optical trapping, atomic force microscopy, and advanced light microscopy. The lab participates in the Triangle Soft Matter Workshop, fostering collaborations with researchers from Duke, UNC Chapel Hill, and NC State University. Current research directions include mechanical responses of suspended cells, tracking non-equilibrium cellular fluctuations, nuclear mechanics, and bacterial membrane mechanics under turgor pressure.

David GraingerView profile

Professor

• Bacterial Chromosome Biology
• Pathogenicity
• Antibiotic Resistance Mechanisms
• +3 more

Professor David Grainger is a faculty member at the University of Birmingham's School of Biosciences, specializing in Molecular Microbiology. He leads the Grainger Lab, focusing on bacterial chromosome biology, pathogenicity, and antibiotic resistance. His research integrates high-throughput techniques and single-molecule analysis to study gene regulation and bacterial pathogenesis. Education: PhD (2004), PGCE (2000), BSc (1999) in Biochemistry from the University of Birmingham. Affiliations: Part of the Institute of Microbiology and Infection (IMI), collaborating with experts in genomics, proteomics, and structural biology. Research Interests: Deciphering chromosome biology of pathogenic bacteria, including transcriptional regulation, toxin production control, and antibiotic resistance pathways. Utilizes cutting-edge methods like Hi-C for 3D chromatin analysis and single-molecule microscopy. Recent Articles: Focused on transposon capture mechanisms, bacterial promoter diversity, and quorum sensing signaling. Highlights include studies on Salmonella regulons and Vibrio cholerae biofilm suppression. Awards: Wellcome Trust Career Development Fellowship (2008), Runner-up in 'Science Snaps' competition for scientific communication. Grants: Career Development Fellowship-funded establishment of his research group at the University of Warwick (2008). Labs/Teams: Grainger Lab at the University of Birmingham, part of the IMI network. Engages in public science outreach via Twitter and lab website.

Mark WallaceView profile

Professor

• Membrane Biology
• Biophysics
• Optical Microscopy
• +3 more

Mark Wallace is a Professor of Chemistry at King's College London, affiliated with the Department of Chemistry and the Faculty of Natural, Mathematical & Engineering Sciences. He holds a Royal Society University Research Fellowship (2005–2016) and has been a lecturer at Oxford University before joining King's in 2016. His research focuses on membrane protein function and artificial membrane mimics, combining optical microscopy and nanotechnology. He earned a PhD from the University of Cambridge (2002) and postdoctoral training at Stanford University and the National Institute for Medical Research. Key research interests include membrane protein dynamics, lipid bilayer engineering, and single-molecule imaging. He has pioneered techniques like droplet interface bilayers and interferometric scattering microscopy. His work has led to patents and applications in molecular sensing and medical research. Awards include the 2002 Gregorio Weber Prize and the 2015 RSC Norman Heatley Award. He is actively involved in public outreach, including video podcasts and educational competitions. Recent publications emphasize artificial ion channels, nanoparticle formation monitoring, and mitochondrial protein dynamics. His lab collaborates with institutions like the London Centre for Nanotechnology and the Rosalind Franklin Institute. Over 30 students and researchers have been mentored, with active grants from EPSRC, Wellcome Trust, and BBSRC.

Matthew LakinView profile

Associate Professor

• Molecular Computing
• DNA Nanotechnology
• Synthetic Biology
• +7 more

Matthew Lakin is an Associate Professor with tenure in the Department of Computer Science at the University of New Mexico, with a courtesy appointment in the Department of Chemical & Biological Engineering. He is affiliated with the UNM Center for Biomedical Engineering and the School of Engineering, and collaborates extensively with the UNM Health Sciences Center and external institutions. Education: Ph.D., Computer Science, University of Cambridge, 2010 M.A. (Cantab), University of Cambridge, 2009 B.A. (Hons), Computer Science, University of Cambridge, 2005 Dr. Lakin's research focuses on molecular computing, DNA nanotechnology, synthetic biology, and formal verification of biomolecular circuits. He develops computational models and experimental systems for programmable biological devices, especially using heterochiral DNA to enhance stability in living cells. His work spans software tools for biodesign and experimental validation in mammalian systems, with applications in nanomedicine and biosensing. The recent publications highlight a strong trend in engineering robust, intelligent biomolecular systems. His work integrates machine learning concepts into chemical reaction networks, advances geometric modeling of DNA systems, and pioneers L-DNA-based circuits for intracellular applications. The research spans theoretical foundations, software tools, and wet-lab experimentation, emphasizing interdisciplinary innovation. Scientific Awards: Presidential Early Career Award for Scientists and Engineers (PECASE), 2025 NSF CAREER Award, 2021 UNM School of Engineering Junior Faculty Research Excellence Award, 2021 Multiple student awards under his mentorship, including the Outstanding Graduate Student Award and DNA28 Best Student Presentation recognition Dr. Lakin has advised numerous graduate and undergraduate students, including Ph.D. graduates in Biomedical Engineering and Computer Science. He leads major funded projects such as the NSF CAREER grant on heterochiral molecular computing, an EPSCoR Research Fellowship, and a $3M NSF grant on heavy metal biosensing in collaboration with Native American communities. He is also PI on multiple NSF grants related to synthetic cells and nucleic acid technologies. He directs the Lakin Lab for Programmable Biology, which operates within the Department of Computer Science and collaborates with Chemical & Biological Engineering and the Center for Biomedical Engineering. The lab emphasizes both computational modeling and experimental molecular biology, and runs an NSF-funded biotechnology summer camp in partnership with ¡Explora! science museum to strengthen STEM education in New Mexico.

Daniel RoxburyView profile

Associate Professor

• Nanoscience
• Carbon Nanotubes
• Nanomaterials
• +4 more

Dr. Daniel Roxbury is an Associate Professor and Graduate Director at the Department of Chemical, Biomolecular and Materials Engineering within the University of Rhode Island's College of Engineering. With expertise in nanoscience and carbon nanomaterials, his research focuses on nano-bio interactions, developing functionalized nanotubes for biomedical applications and environmental monitoring through his NanoBio Engineering Laboratory. His work spans multiple disciplines including: Biomedical nanosensors Smart wearable biomaterials Targeted drug delivery systems Environmental nanotechnology Single-molecule imaging Nanotoxicology Recent publications emphasize machine learning-enhanced spectral analysis, coral reef conservation nanotechnology, and wearable stress monitoring textiles. His 2024 ACS Nano study introduces AI-driven macrophage phenotyping, while 2023 Nature Nanotechnology work explores coral reef restoration strategies using nanomaterials. Awarded the 2019 NSF CAREER grant for cellular nanometrology, he leads multiple NIH-funded projects including: $820,000 NSF CAREER: Spectral Imaging for Sub-Cellular Nanometrology $140,000 Miriam Hospital COBRE: Cortisol Detection Textiles $700,000 NSF EAGER: Multiplexed Wound Biomarker Detection His laboratory houses state-of-the-art equipment including: Near Infrared Hyperspectral Microscope Custom NIR Fluorescence Spectrometer Jasco UV/VIS/NIR Spectrophotometer Biosafety Cabinet Cell Culture Incubator Cryo-Storage System

• Biophysical Immunology
• Mechanobiology
• Microscopy Technology
• +3 more

Marco Fritzsche is a Professor of Biophysical Immunology at the University of Oxford. He serves as the Scientific Director of the Oxford-ZEISS Centre of Excellence and leads the Biophysical Immunology Laboratory (www.bpi-oxford.com), which operates at the intersection of biophysics and immunology. BSc in Mathematics (2003–2006), University of Saarbrücken BSc in Physics (2003–2006), University of Saarbrücken MSc in Theoretical Physics (2006–2008), University of Saarbrücken PhD in Experimental Physics and Biology (2008–2012), University College London His research focuses on biophysical and mechanobiological mechanisms governing immune responses in health and disease. The BPI Laboratory develops advanced microscopy technologies to study these processes, integrating theoretical physics with experimental immunology. Recent publications highlight his work in quantitative imaging of biomolecular organization , traction force microscopy for immune cell dynamics, and trans-synaptic vesicle analysis in T-cell interactions. His studies bridge disciplines like biophysics, immunology, and cell mechanics. Rosalind Franklin Kennedy Trust Research Fellow The BPI Laboratory collaborates with institutions such as the Howard Hughes Medical Institute Janelia Farm and the Rosalind Franklin Institute . His roles include leadership in the Oxford-ZEISS Centre of Excellence and contributions to cutting-edge immunology research.

Jonathan BaughView profile

Professor

• Quantum Information Science
• Nanoelectronics
• Semiconductor Devices
• +4 more

Jonathan Baugh is a Professor in the Department of Chemistry at the University of Waterloo, serving as Director of the Quantum Information Graduate Program. His research focuses on quantum devices, nanoelectronics, and molecular electronics with affiliations at the Institute for Quantum Computing and Waterloo Institute for Nanotechnology. He leads the Baugh Research Lab, exploring quantum control, semiconductor spin qubits, and superconducting hybrid systems. Research interests include quantum information processing, nanoscale charge transport, and the development of next-generation photonic sources. His work bridges quantum physics and materials science, with recent breakthroughs in dopant-free semiconductors and single-molecule transistors. Publications emphasize scalable quantum architectures, noise mitigation in quantum control, and phase-coherent molecular electronics. Current projects involve cryogenic CMOS device modeling and topological quantum computing in silicon-based systems. No awards are explicitly listed, though his work has been highlighted in invited reviews and special sessions on quantum systems. Advising focuses on graduate students in quantum nanotechnology and condensed matter physics. His lab collaborates on integrated quantum networks and III-V/Si nanowire photodetectors. Labs/Teams: Baugh Research Lab (Quantum Nanoelectronics Group), Institute for Quantum Computing (IQC), Waterloo Institute for Nanotechnology (WIN).

Kathrin LangView profile

Professor

• Chemical Biology
• Protein Engineering
• Genetic Code Expansion
• +3 more

Kathrin Lang is a Full Professor at the Department of Chemistry and Applied Biosciences, ETH Zurich, and Head of the Organic Chemistry Laboratory. Her research focuses on chemical biology, particularly the development of tools for genetic code expansion to incorporate non-canonical amino acids into proteins and advance bioorthogonal chemistries for studying biological processes. Keywords: Genetic Code Expansion, Bioorthogonal Chemistry, Protein Engineering, Ubiquitylation Networks, Post-Translational Modifications. Lang’s work emphasizes proximity-triggered crosslinking reactions, bioorthogonal labeling, and in vivo chemistries to address challenges in protein interaction mapping and structural elucidation. Her group’s recent publications highlight methodologies for dual protein labeling, deciphering ubiquitin code, and enhancing cycloaddition reactivity. Current projects include exploring cyclopropene-fused dibenzocyclooctynes for improved labeling and investigating methylated lysine as a conformational regulator in Hsp90. Funding sources include the ERC (Ubl-tool), DFG (SFB1035, SPP1926), and ETH Zurich. She contributes to education through courses like Genetic Code Expansion for Studying Posttranslational Modifications and Chemical Biology and Synthetic Biochemistry . Collaborative efforts span structural biology, microbiology, and synthetic biochemistry, with applications in ubiquitin research and cellular imaging.

Jennifer CurtisView profile

Professor

• Biophysics
• Cell Mechanics
• Glycobiology
• +5 more

Jennifer Curtis is a Full Professor in the School of Physics at Georgia Institute of Technology and serves as an ADVANCE Professor for the College of Sciences. Her research focuses on the physics of cell-cell and cell-extracellular matrix interactions, particularly within glycobiology and immunobiology contexts. Dr. Curtis earned her Ph.D. in Physics from the University of Chicago (2002) and her B.A. in Physics from Columbia University (1997). Her research interests span biophysics at interfaces, quantitative modeling of collective cellular interactions, cell mechanics, motility, adhesion, and the role of bulky sugars in tissue organization. Her laboratory investigates collective and single cell migration, immunophage therapy (combining immune cells with phages to combat bacterial infections), and molecular biophysics of hyaluronan synthase. Recent work demonstrates applications in soft materials, biomaterials, tissue engineering, and advanced characterization techniques. Analysis of her publication record reveals consistent focus on glyco-biophysics and cellular mechanics, with increasing emphasis on microbial communities and therapeutic applications. Her work bridges physics, biology, and engineering through interdisciplinary approaches. Honors include the NSF CAREER Award (2010), Georgia Tech College of Sciences Faculty Mentor Award (2015), and Cullen Peck Award (2020). She serves on the Biophysical Journal editorial board. Dr. Curtis actively mentors students through the Georgia Tech Physics REU program (which she directs) and collaborates with biologists, chemists, and materials scientists. Her laboratory maintains strong partnerships with institutions including Emory University and international collaborators. The Curtis Lab operates the Cell Physics Laboratory in the Molecular Science & Engineering Building, utilizing advanced techniques including holographic optical tweezers, thermochemical nanolithography, and single-molecule imaging to study cellular mechanics and polymer physics at biological interfaces.

• Free-Electron Lasers
• Ultrafast X-ray Spectroscopy
• Nanoparticle Dynamics
• +3 more

Christoph Bostedt holds dual appointments as a Professor of Physical Chemistry at the Ecole Polytechnique Fédérale de Lausanne (EPFL) and as Head of the Laboratory for Synchrotron Radiation and Femtochemistry (LSF) at the Paul Scherrer Institut (PSI). He leads strategic operations for the LSF, managing five research groups and overseeing four beamlines at the Swiss Light Source and the Alvra Endstation at SwissFEL. His research focuses on ultrafast x-ray science, including single-shot imaging, non-linear x-ray spectroscopy, and femtosecond pump-probe techniques. He collaborates globally on initiatives like the Athos project, aiming to advance ultrafast x-ray technologies. Bostedt has over 150 publications and is a Fellow of the American Physical Society, recipient of the Röntgen Prize. Education: Ph.D. from the University of Hamburg with research at Lawrence Livermore and Berkeley National Laboratories. Prior roles include leadership at Argonne National Laboratory and SLAC National Accelerator Laboratory. Research Interests: Single-particle imaging and coherent diffraction X-ray free-electron laser applications Ultrafast dynamics in nanoparticles and molecular systems Non-linear x-ray spectroscopy Time-resolved x-ray pump-probe methods Awards: Fellow of the American Physical Society Röntgen Prize (University of Giessen) Labs & Projects: Spearheads the Athos beamline project at SwissFEL, developing the Maloja endstation for ultrafast x-ray studies. Oversees the Laboratory for Femtochemistry and collaborates on advanced imaging techniques for nanoscale science.

Angela KouView profile

Assistant Professor

• Quantum Information
• Condensed Matter Physics
• Superconducting Circuits
• +2 more

Angela Kou is an Assistant Professor in the Department of Physics at the University of Illinois at Urbana-Champaign, specializing in the intersection of quantum information science and condensed matter physics. Her laboratory develops novel superconducting circuit elements and qubits, while also utilizing superconducting circuits to investigate topological materials with potential applications in quantum computing. She actively seeks postdoctoral researchers and graduate students to explore superconducting qubit engineering and quantum material sensing. Her research integrates quantum information , topological materials , and superconducting circuit design . Recent publications demonstrate expertise in fluxonium qubit control , quantum dot Josephson junctions , and parafermion zero modes in exotic heterostructures. She contributes to advancing cryogen-free dilution refrigerator technology for scanning probe microscopy applications. Current research trends focus on quantum coherence optimization , phase-slip qubit operation , and vibration mitigation in cryogenic systems. Her work receives support from the Air Force Office of Scientific Research, Army Research Office, IBM-Illinois Discovery Accelerator Institute, and the National Science Foundation. Collaborations span multiple institutions, with key partnerships at Stanford University and SLAC National Accelerator Laboratory. Her technical contributions include microwave impedance microscopy , scanning single-electron transistor measurements , and vibration analysis for quantum device stability.