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Britt AdamsonView profile

Associate Professor

• Stress Response Networks
• DNA Damage Response
• Genome Editing
• +3 more

Britt Adamson is an Associate Professor in the Department of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, where she serves as Director of the Undergraduate Program in Quantitative and Computational Biology. Her lab investigates molecular networks in human cells with focus on stress response mechanisms and genome editing technologies. She received her B.S. in Biology from the Massachusetts Institute of Technology (2005) and Ph.D. in Genetics and Genomics from Harvard University (2012), followed by postdoctoral training at UCSF under Jonathan Weissman supported by a Damon Runyon Cancer Research Foundation Fellowship. Adamson's research centers on how cells organize stress response networks during DNA damage and endoplasmic reticulum stress, developing CRISPR-based functional genomics and single-cell sequencing tools to map molecular behaviors. Her work bridges fundamental cell biology with therapeutic applications in genome editing. Analysis of her 15 most recent publications reveals dominant themes in precision genome editing (prime/base editing optimization) and systematic dissection of DNA repair pathways through combinatorial CRISPR screening. Her lab consistently integrates computational approaches with high-resolution experimental techniques to uncover context-dependent cellular behaviors. Her scientific recognitions include: Damon Runyon Cancer Research Foundation Postdoctoral Fellowship Princeton IP Accelerator Award (2025) STAT Who to Know: 10 Scientists leading a new generation of gene editors (2024) Adamson actively mentors eight graduate students (including alumni Ann Cirincione and Jun Hussmann) and two postdocs, with research funded through institutional awards and collaborative grants. Her lab's technological developments have enabled projects spanning virology, immunology, and developmental biology. The Adamson Lab operates within Princeton's Lewis-Sigler Institute for Integrative Genomics, fostering an interdisciplinary environment that merges cell biology, genomics, and computational science. Current projects focus on improving prime editing efficiency and understanding stress response adaptation in disease contexts.

Hayden Kwok Hay SOView profile

Associate Professor

• Reconfigurable Computing
• FPGA-Based Systems
• Computer Architecture
• +7 more

Prof. Hayden Kwok Hay SO is an Associate Professor at the University of Hong Kong (HKU), affiliated with the Department of Electrical and Electronic Engineering. He currently serves as Acting Director of the School of Innovation and previously co-directed the Computer Engineering Program. His research focuses on reconfigurable computing systems, FPGA-based architectures, and their applications in AIoT, medical imaging, and high-performance computing. He holds a B.S., M.S., and Ph.D. in Electrical Engineering and Computer Sciences from UC Berkeley (1998–2007). Prof. So has been recognized with awards such as the IEEE-HKN Teaching Award (2021), Croucher Innovation Award (2013), and multiple teaching excellence awards. He leads the Computer Architecture & System Research Lab (CASR) and co-founded the Joint Lab on Future Cities (JLFC). His work spans FPGA overlay architectures, graph processing systems, and hardware-software co-design for efficient computing. Key research contributions include advancements in FPGA-based reconfigurable systems, sparse dataflow architectures, and medical imaging accelerators. He has secured grants for projects like 'Advanced machine vision guided aquatic surface vehicles' and 'Efficient and Productive Parallel Data Processing in Hybrid FPGA-CPU Clusters.' Prof. So has advised numerous students and researchers, contributing to over 150 peer-reviewed publications. His current projects explore AI hardware acceleration, neuromorphic computing, and FPGA-driven solutions for big data challenges.

Vadim CherezovView profile

Professor

• Membrane Protein Structure and Function
• G Protein-Coupled Receptors (GPCRs)
• Lipid-Protein Interactions
• +3 more

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

Emma PiersonView profile

Assistant Professor

• Artificial Intelligence
• Healthcare
• Health Equity
• +3 more

Emma Pierson is an Assistant Professor of Computer Science at the University of California, Berkeley, affiliated with the Berkeley Artificial Intelligence Research Lab (BAIR) , Computational Precision Health , and the Center for Human-Compatible AI . She focuses on developing data science and machine learning methods to address issues in healthcare equity and social inequality . Her work includes studies on race adjustments in clinical algorithms, migration patterns, and leveraging LLMs for health equity. Education: Ph.D. in Computer Science from Stanford University (2020), Master’s in Statistics from the University of Oxford. Prior roles include Assistant Professor at Cornell Tech, Senior Researcher at Microsoft Research, and data scientist at 23andMe and Coursera. Research Interests: Her research spans fair clinical prediction , sparse autoencoders , health disparities , and algorithmic fairness . Notable projects include the MIGRATE dataset for granular migration analysis and studies on policing disparities. Awards: NSF CAREER Award, Rhodes Scholarship, Hertz Fellowship, MIT Technology Review 35 Innovators Under 35, and Samsung AI Researcher of the Year. She writes a statistics blog ( Obsession with Regression ) and contributes to media outlets like The New York Times and FiveThirtyEight . Labs/Teams: Leads the MIGRATE project, a collaboration to analyze fine-grained migration data. Engages in interdisciplinary work across AI, healthcare, and social science.

Itsik Pe'erView profile

Professor

• Human Genetics
• Computational Biology
• Genomics
• +3 more

Itsik Pe'er is a Full Professor and Vice-Chair in the Department of Computer Science at Columbia University's Fu Foundation School of Engineering & Applied Science, and holds a joint appointment as Professor of Systems Biology at the Vagelos College of Physicians and Surgeons. His research focuses on computational methods in human genetics, including genetic variation analysis, disease association studies, and algorithm development for genomic data. He leads the Itsik Pe'er Lab of Computational Genomics, which develops tools like Xplorigin, Germline, and SEACells to address challenges in genomics and medical research. His work spans machine learning applications in healthcare, microbiome analysis, and cancer genomics. Notable contributions include studies on hypertensive disorders in pregnancy, bias correction in predictive models, and the development of non-Euclidean learning libraries like Manify. Pe'er has advised students including Vladimir Vacic, Anat Kreimer, and Arthi Ramachandran, and collaborates on grants addressing genetic epidemiology and computational biology. His lab's location is in the Computer Science Building at Columbia's Morningside Campus.

• Immunology
• Genomics
• Multiomics Analysis
• +3 more

Calliope Dendrou is an Associate Professor in Clinical Pathology and Inflammation at the Kennedy Institute of Rheumatology (KIR), University of Oxford, leading the Immune Disease Multiomics Laboratory. She previously held a Wellcome & Royal Society Sir Henry Dale Fellowship at the University of Oxford’s Centre for Human Genetics before joining KIR in 2023. Her research focuses on immune disease mechanisms using multiomics approaches, including genomic profiling to identify therapeutic targets across tissues and immune-mediated diseases. She co-leads large-scale projects like the Oxford-J&J Cartography Consortium and the Chan Zuckerberg Initiative’s LEGACY Network, and teaches on the MSc in Genomic Medicine program. Educational Background: BSc (Biology, Imperial College London, 2005; Forbes Memorial Medal Winner); PhD in Infection & Immunity (University of Cambridge, 2010). Postdoctoral training at the Weatherall Institute of Molecular Medicine under Prof. Lars Fugger. Research interests include immunogenetics, cytokine signaling pathways, drug repositioning, and cross-disease pathophysiology. Her work integrates single-cell and spatial transcriptomics to dissect immune-cell interactions in diseases like rheumatoid arthritis, inflammatory bowel disease, and celiac disease. Recent articles highlight her contributions to understanding vaccine adjuvant responses, Th17 cell roles in spondyloarthritis, and immune-epithelial networks in celiac disease. Collaborations emphasize multi-omic data analysis (e.g., Panpipes pipeline) and translational studies toward precision medicine. Awards: Forbes Memorial Medal (BSc), Wellcome & Royal Society Sir Henry Dale Fellowship. Leadership roles include Equality, Diversity, and Inclusion Champion and 'Single-Cell & Spatial Omics for Precision Medicine' Module Lead. Lab & Teams: Immune Disease Multiomics Lab at KIR. Active in collaborative initiatives such as the LEGACY Network, focusing on large-scale immune profiling in ancestrally diverse populations.

Ahmet AcarView profile

Associate Professor

• Cancer Biology
• Precision Medicine
• Drug Resistance Mechanisms
• +3 more

Dr. Ahmet Acar is an Associate Professor at the Department of Biological Sciences, Middle East Technical University (METU), Ankara, Turkey. He leads the Cancer Precision Medicine and Drug Resistance Laboratory, focusing on understanding mechanisms of drug resistance in cancer. His research integrates experimental models, next-generation sequencing, and deep learning to address clinical challenges in cancer therapy. Dr. Acar holds a B.Sc. from METU's Biological Sciences department and a Ph.D. from the Cancer Research UK Manchester Institute. He completed postdoctoral training at the Institute of Cancer Research, London, and the University of Manchester. Research Interests: Drug resistance mechanisms, precision oncology, tumor microenvironment modeling, patient-derived organoids, computational pathology, and evolutionary cancer biology. His lab develops 2D/3D co-culture systems, PDO biobanks, and AI-driven histopathology tools to improve treatment strategies. Recent Work Trends: Recent publications emphasize tumor evolution modeling, matrix mechanics in drug resistance, and AI applications in histopathology. Collaborations with hospitals in Turkey and Europe support PDO biobank initiatives. His team explores evolutionary steering strategies to exploit collateral drug sensitivities. Labs/Teams: Precision Medicine and Drug Resistance Lab at METU focuses on interdisciplinary approaches combining wet-lab experiments with computational methods. Current projects include ex vivo tumor modeling and AI-driven diagnostic tools for oncology.

Kathryn RoederView profile

Professor

• Statistical Genetics
• Genomics
• Biostatistics
• +5 more

Kathryn Roeder is the UPMC University Professor of Statistics and Life Sciences at Carnegie Mellon University (CMU), affiliated with the Dietrich College of Humanities and Social Sciences and the Departments of Statistics & Data Science and Computational Biology. Her research focuses on developing statistical methods for genetic and genomic data, particularly in identifying autism risk genes and analyzing single-cell multi-omic data. She earned her Ph.D. in Statistics from Penn State University and has been at CMU since 1994, previously serving as Vice Provost for Faculty (2015–2019). Education: Ph.D. in Statistics, Penn State University (1988) B.S. in Wildlife Resources, University of Idaho (1982) Research Interests: Her work integrates modern statistical techniques (high-dimensional statistics, machine learning, networks) to study complex diseases like autism and schizophrenia. Recent efforts include tools for analyzing single-cell RNA-seq and proteomic data, such as UNICORN, DAWN, and SCEPTRE. Key Awards: COPSS Distinguished Achievement Award (2020) National Academy of Sciences Member (2019) COPSS Presidents’ Award (1997) AAAS Fellow (2020) Advising & Grants: She has advised over 20 Ph.D. students, many contributing to landmark studies in autism genetics. Her grants include NIH funding for projects like the Autism Sequencing Consortium. Current research teams focus on computational biology and statistical genetics. Labs & Collaborations: Her lab develops software tools (e.g., TADA, MIND) and collaborates with the Autism Sequencing Consortium and iPSYCH-BROAD Consortium on large-scale genomic studies.

Kelly ArnoldView profile

Associate Professor

• Biomedical Computation and Modeling
• Drug Delivery and Therapeutics
• Systems Immunology
• +5 more

Kelly Arnold is an Associate Professor in the Department of Biomedical Engineering at the University of Michigan. Her research integrates systems engineering principles with immunology to investigate variability in immune responses across infection, vaccination, and injury, with a focus on computational modeling and clinical translation. Research Focus Systems-level immune response modeling Vaccination and antibody functionality Vaginal microbiome-host interactions Chronic lung disease progression Computational serology and proteomics Recent Work Her 2025 studies examine SARS-CoV-2 vaccination responses in cancer patients and computational frameworks for vaginal probiotics. Earlier works (2024-2007) span COPD progression, lupus fibrosis, HIV susceptibility, and tissue engineering for fertility preservation. Methodologies include proteomic profiling, network modeling, and microfluidic systems.

• Machine Learning
• Genomics
• Gene Regulatory Networks
• +3 more

Sushmita Roy is a Professor at the University of Wisconsin–Madison, affiliated with the Department of Computer Sciences and the College of Letters and Science. Her research focuses on developing computational methods in statistical machine learning to understand gene regulatory networks in living cells, particularly under environmental, developmental, disease, and evolutionary contexts. She explores bulk and single-cell genomic data integration to study processes like cell fate specification, host-microbe interactions, and diseases such as cancer and neurodevelopmental disorders. Her work emphasizes three key areas: inference of genome-scale transcriptional networks, evolutionary analysis of regulatory networks, and 3D genome organization dynamics. Roy’s lab collaborates across disciplines, leveraging genomic data from plant and mammalian systems. She has contributed to methodologies for analyzing chromatin accessibility, single-cell profiling, and network-based models of pathogen systems. Her affiliations include Wisconsin Institutes for Discovery, and she is a leader in computational biology and systems genomics research.

• Bioinformatics
• Genomics
• Transcriptomics
• +6 more

Owen R. White is a Professor in the Department of Epidemiology & Public Health at the University of Maryland School of Medicine, serving as Associate Director of the Institute for Genome Sciences and Associate Director of Research Collaboration & Development. He leads a team of 25 scientists and engineers developing genomic annotation pipelines and data analysis tools for state-of-the-art research in microbiome and multi-omic studies. His academic background includes: BS in Biotechnology from the University of Massachusetts (1985) PhD in Molecular Biology from New Mexico State University (1992) Postdoctoral Fellowship in Genome Informatics at the Institute for Genomic Research (TIGR) (1994) Dr. White's research spans bioinformatics, genomics, transcriptomics, and metagenomics with emphasis on data management, metadata standards, ontologies, and cloud systems. His work has been foundational for large-scale initiatives like the Human Microbiome Project (HMP) and Integrative Human Microbiome Project (iHMP), generating over 50,000 datasets totaling 10 terabytes of multi-omic data. Analysis of his recent publications reveals a strong trend toward neuroscience multi-omics (BRAIN Initiative), cloud-based data infrastructure, and ethical data sharing frameworks. His work consistently bridges microbiome research with emerging fields like single-cell analysis and Alzheimer's disease biomarker discovery through integrated data platforms. Notable awards include: Benjamin Franklin Award for Open Access in the Life Sciences (2015) Kumho Science International Award in Plant Molecular Biology and Biotechnology (2001) As Principal Investigator for major NIH-funded centers, he has secured sustained support for the HMP Data Analysis and Coordination Center and iHMP Data Coordination Center. His team's work combines fee-for-service models with collaborative research funding to maintain cutting-edge genomic analysis capabilities. The Institute for Genome Sciences houses his computational team responsible for developing production annotation pipelines, database systems, and visualization tools that serve researchers across the University of Maryland School of Medicine and national consortia.

Matthias MannView profile

Professor

• Mass Spectrometry
• Proteomics
• Systems Biology
• +6 more

Professor Matthias Mann is a world-leading scientist serving as Director of the Proteomics and Signal Transduction department at the Max Planck Institute of Biochemistry in Martinsried, Germany, and Director of the Proteomics department at the Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Denmark. With an h-index exceeding 277 and over 350,000 citations, he is recognized as the highest cited German researcher and one of the most influential scientists globally in proteomics. His educational background includes: Ph.D. in Chemical Engineering from Yale University (1988) Master's Degree in Physics from Georg August University Göttingen (1984) Bachelor's of Arts in Mathematics from Georg August University Göttingen (1982) Professor Mann's research focuses on advancing mass spectrometry-based proteomics to understand biological systems at the protein level. His work spans technological developments in mass spectrometry, bioinformatics and computational analysis, signal transduction and posttranslational modifications, and clinical proteomics applications for disease diagnosis and treatment. The Mann lab has pioneered groundbreaking methods like SILAC for quantitative proteomics and MaxQuant for proteome data analysis. Their vision is to translate proteomics knowledge into clinical practice for predictive, diagnostic, and preventive medicine, with recent work focusing on AI-guided platforms for analyzing proteomes from minimal tissue samples. Analysis of Professor Mann's recent publications reveals a strong trend toward clinical applications of proteomics, particularly in cancer research, metabolic diseases, and neurodegenerative disorders. His work increasingly integrates spatial proteomics, single-cell resolution techniques, and artificial intelligence approaches to uncover disease mechanisms and identify potential biomarkers, with a clear shift from basic technology development toward direct clinical applications and personalized medicine. Professor Mann has received numerous prestigious awards throughout his career: 2025: Elected member of the American National Academy of Sciences 2024: Dr. H.P. Heineken Award for Biochemistry and Biophysics 2023: Otto Warburg Medal 2019: Nominated member of the Bavarian Academy of Sciences 2013: Elected member of Leopoldina German National Academy of Sciences 2012: Körber European Science Award, Louis-Jeantet Foundation Prize for Medicine, Ernst Schering Prize, and Leibniz Prize Professor Mann leads a highly collaborative research team involved in multiple international networks including the Bill & Melinda Gates Foundation, Michael J. Fox Foundation for Parkinson's Research, CLINSPECT-M, and Munich Heart Alliance. His lab has mentored numerous successful researchers, with several former postdocs receiving prestigious ERC Starting Grants. The Mann group has developed innovative clinical proteomics pipelines for analyzing archived tissue specimens and body fluids, aiming to identify protein markers for early detection of diseases such as diabetes and cancer. The Mann lab operates across two major research centers with state-of-the-art mass spectrometry facilities. Their Clinical Knowledge Graph platform integrates multi-omics data with extensive metadata, creating an ecosystem for machine learning applications in proteomics. Current research focuses on developing highly sensitive methods that can profile thousands of proteins from minimal cell samples, enabling the identification of critical disease-related proteins and supporting the development of individualized therapies.

Daiwei ZhangView profile

Assistant Professor

• Artificial Intelligence
• Machine Learning
• Spatial Omics
• +3 more

Daiwei (David) Zhang, PhD, is an Assistant Professor (tenure-track) in the Department of Biostatistics at the University of North Carolina at Chapel Hill School of Medicine, with a joint appointment in the Department of Genetics. His research focuses on developing AI frameworks for analyzing high-dimensional biomedical data, particularly in spatial omics, computational pathology, and medical imaging. Education: MS (Biostatistics) and PhD (Biostatistics and Scientific Computing) from the University of Michigan. Postdoctoral Training: University of Pennsylvania. Research interests include applying machine learning to address biomedical challenges such as tumor heterogeneity, immune interactions, and tissue architecture. His work spans computational methods for spatial transcriptomics, proteomics, and histology integration. Recent publications emphasize spatial multi-omics analysis of cancer ecosystems, tertiary lymphoid structures, and metabolic coordination. These studies leverage advanced machine learning algorithms and interdisciplinary approaches to advance precision medicine. No scientific awards are explicitly mentioned, but his work reflects significant contributions to biomedical AI research. Grants and advising details are not provided in the text.

• Microbiology
• Infectious Diseases
• Cell Biology
• +7 more

Manuel R. Amieva is a Professor at Stanford University School of Medicine , holding joint appointments in Pediatrics - Infectious Diseases and Microbiology & Immunology . He is also a member of the Maternal & Child Health Research Institute (MCHRI) . His clinical practice at Stanford Medicine Children's Health focuses on pediatric infectious diseases. Education: Medical Education: Stanford University School of Medicine (1997) Fellowship: Stanford University Pediatric Infectious Disease Fellowship (2004) Internship & Residency: Stanford Health Care at Lucile Packard Children's Hospital (1998-1999) Dr. Amieva's research investigates host-pathogen interactions at epithelial barriers, with specific expertise in Helicobacter pylori , Listeria monocytogenes , Salmonella enterica , and Staphylococcus aureus . His lab develops innovative organoid culture systems with controlled polarity to study microbial colonization and oncogenic mechanisms. Key discoveries include: H. pylori's manipulation of epithelial junctions via the CagA protein Listeria's exploitation of cell extrusion sites for invasion Staphylococcus toxin interactions with adherens junctions Gastric stem cell activation by pathogens Recent publication trends show continued leadership in infectious disease mechanisms (2020-2025), with a focus on: Pathogen-specific epithelial breach strategies Organoid modeling of viral/bacterial interactions Redox-dependent host factor regulation Single-cell spatial transcriptomic analyses Multi-institutional educational frameworks His scientific collaborations span disciplines including: Gastric cancer genomics initiatives COVID-19 lung infection models Stem cell-microbe interactions Medical education reform projects Dr. Amieva maintains active clinical research while mentoring students in both the Microbiology & Immunology and Pediatrics programs. His lab at Stanford employs advanced 3D confocal microscopy and organ-on-a-chip technologies to visualize epithelial colonization dynamics.

Knut DrescherView profile

Associate Professor

• Bacterial Biofilms
• Microbial Multicellularity
• Biophysics
• +5 more

Prof. Knut Drescher is an Associate Professor at the Biozentrum, University of Basel , leading a research group focused on bacterial biofilms , swarming , and microbial multicellularity . Previously, he served as a Professor of Biophysics and Max Planck Research Group Leader at Philipps-Universität Marburg (2015-2021) and conducted postdoctoral research at Princeton University. Research Interests: Physical and biological mechanisms of biofilm formation Cell-cell interactions in microbial communities Antibiotic resistance in biofilms Hydrodynamics of bacterial swarms Evolution of cooperation in multispecies biofilms Development of bioimaging software (BiofilmQ, BacStalk) Scientific Awards: 2023: SNSF Consolidator Grant 2019: Heinz Maier-Leibnitz Prize (DFG), VAAM Research Prize, IUPAP Young Scientist Prize 2016: ERC Starting Grant Advising & Grants: Advises PhD and Master's students in microbiology, biophysics, and bioinformatics Secured major grants from ERC , HFSP , and DFG