Yuhui HuView profile
Associate Professor
Yuhui Hu is an Associate Professor and Doctoral Supervisor in the Department of Pharmacology, School of Medicine at Southern University of Science and Technology (SUSTech) in Shenzhen, China. She joined SUSTech in August 2016 as an independent PI and was promoted to Associate Professor in the Department of Pharmacology in March 2022, having previously served as a Research Associate Professor in the Department of Biology, School of Life Sciences at SUSTech from 2016-2022. Dr. Hu earned her Ph.D. in Functional Genomics from the Max Planck Institute for Molecular Genetics in Berlin, Germany in 2006. Prior to joining SUSTech, she led her own research group on pharmacogenomics and chemical genetics at the same institute from 2007-2009, then moved to the Berlin Institute for Medical Systems Biology (BIMSB) at the Max Delbrück Center for Molecular Medicine where she served as a Senior Research Scientist until 2016. Her research focuses on integrating diverse systems biology approaches in transcriptomics, genomics/epigenomics, proteomics, CRISPR gene editing, single-cell and spatiotemporal omics to decipher gene regulations in cancer precision medicine and developmental biology. She has pioneered high-throughput platforms for protein subcellular localization, apoptosis detection, and protein-protein interaction analysis. Her work bridges traditional Chinese medicine compounds with modern systems biology approaches to develop new drugs, particularly through the investigation of natural compounds for anticancer and anti-COVID applications. Her recent publications show a strong focus on cutting-edge single-cell and spatial transcriptomics technologies, with multiple high-impact papers in journals like Cell, Nature Communications, and Developmental Cell. Her research group has developed several innovative protocols for sample multiplexing and cell death quantification compatible with single-cell sequencing. Excellent Patent Award, Southern University of Science and Technology (2020) Industrial Development and Innovative Talent Award, Shenzhen (2021) Shenzhen Peacock Talent Award As a Doctoral Supervisor, Dr. Hu leads a research group that has secured significant funding, including six national/provincial projects totaling over ¥7.14 million. She serves as a core PI in the Shenzhen Key Laboratory of Gene Regulation and Systems Biology and holds several academic society positions, including committee member of the division of anti-inflammatory and immunological pharmacology of the Chinese Pharmacological Society, council member of Guangdong Pharmacological Society, and executive director of Guangdong Overseas Returnees Association. Her lab continues to develop novel systems biology approaches for gene regulation and pharmacology research, with a particular focus on cancer genomics and chemical genomics for early diagnosis, therapy, and prognosis.









