Joachim KrugView profile
Professor
Prof. Joachim Krug is a Professor at the University of Cologne's Institute for Theoretical Physics, affiliated with the Center for Data and Simulation Science. His research focuses on theoretical models of evolutionary biology, particularly population genetics and fitness landscapes. He investigates how populations adapt to new environments, emphasizing the role of epistasis, mutational pathways, and evolutionary predictability, with applications to antibiotic resistance in microbes. Key research areas include the geometry of fitness landscapes, clonal interference in large populations, and the interplay between recombination and evolutionary robustness. His work bridges statistical physics and biology, applying concepts from stochastic processes and nonlinear dynamics to evolutionary systems. Notable contributions include studies on evolutionary accessibility, adaptive walks, and the role of deleterious mutations in long-term evolution. Publications highlight interdisciplinary approaches, such as analyzing β-lactamase resistance mechanisms in E. coli and developing models for RNA translation dynamics. His research underscores the importance of quantitative methods in understanding evolutionary processes and predicting evolutionary trajectories.








