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Kathrin PlathView profile

Professor

University of California, Los AngelesUnited States

Kathrin Plath, Ph.D., is a Professor and Vice Chair in the Department of Biological Chemistry at the David Geffen School of Medicine, University of California, Los Angeles (UCLA) . Her research focuses on epigenetic regulation of cell fate transitions, particularly in stem cell biology, reprogramming, and X-chromosome dynamics. Education: Ph.D., Biochemistry, Humboldt University, Germany (1999) Post-doctoral Fellowships: Stem Cell Biology (Whitehead Institute, 2006), Chromatin Biology (UC San Francisco, 2003), Cell Biology (Harvard Medical School, 2000) Research Interests: Plath investigates mechanisms governing pluripotency, X-chromosome inactivation, and nutrient regulation of stem cell differentiation. Her lab develops single-cell omics technologies like SEC-seq to study transcriptomes and secretomes simultaneously, and explores 3D genome organization's role in gene regulation. Scientific Awards: HHMI Faculty Scholar (2016) ISSCR Board of Directors (2011-2017) NIH Director’s New Innovator Award (2007) Kimmel Foundation Scholar (2007) V Foundation Scholar (2007) Advising & Collaborations: Mentors students like Clara Cano and Sasha Barinsky. Collaborates with Jason Ernst (UCLA), Dino Di Carlo (UCLA), and international researchers on projects involving iPSC reprogramming, X-chromosome dosage compensation, and lung disease modeling.

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Alvaro SagastiView profile

Professor

University of California, Los AngelesUnited States

Alvaro Sagasti is a Professor in the Department of Molecular, Cell, & Developmental Biology at the University of California, Los Angeles (UCLA), within the College of Life Sciences. His research focuses on the morphogenesis of sensory neurons and epithelial cells in zebrafish, particularly examining axon development, regeneration, and neuron-skin cell interactions. PhD: University of California, San Francisco (UCSF), studying left/right asymmetry in C. elegans Postdoc: Skirball Institute, NYU Medical Center, with Alex Schier Grass Foundation Fellow: Marine Biological Lab (2005) Research interests include: Neuronal morphogenesis (axon branching, sensory territory partitioning) Microridge formation in epithelial cells Calcium dynamics in axon degeneration Neuroinflammatory responses Developmental pruning and regeneration His lab uses zebrafish models for live imaging, genetic manipulations, and transcriptomic analyses. Recent publications (2020-2025) emphasize cortical contraction mechanisms in microridge morphogenesis, axon-epithelial interactions, and molecular pathways in axon regeneration. Scientific awards include: Grass Foundation Fellowship (2005) Former lab members (Jeff Rasmussen, Ana Palanca, Kelly O'Donnell) have transitioned to academic, medical, or industry positions. Current projects investigate axon migration, microridge mechanical regulation, and neuroepithelial communication in skin development.

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Stephanie WhiteView profile

Professor

University of California, Los AngelesUnited States

Stephanie White , a Professor in the Department of Integrative Biology & Physiology at the College of Life Sciences , University of California, Los Angeles, investigates the interplay between social behaviors and neuronal plasticity in zebra finches . Her research focuses on how vocal learning—a critical reproductive behavior—is shaped by gene expression and neural circuitry, particularly through comparative studies of sexually dimorphic brain structures. Her recent publications highlight diverse research directions, from genomic analyses of domestication syndrome in songbirds to RNA diagnostics and clinical implications in neurodevelopmental disorders . Collaborative studies include FOXP2 transcriptional targets and microRNA regulation in vocal learning . Stephanie’s lab employs behavioral experiments , electrophysiology , and molecular techniques to explore how social interactions modulate gene expression and neural properties. She also contributes to interdisciplinary discussions on genetics in palliative care and terminology standardization in genomics . Contact: sawhite@ucla.edu | Lab Website

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Herbert SchillerView profile

Professor

Helmholtz Centre MunichGermany

Herbert Schiller is a Director of the Research Unit for Precision Regenerative Medicine (PRM) at Helmholtz Munich and a Professor for Systems Biology of the Airways and Lungs at the Medical Faculty of Ludwig Maximilian University (LMU) Munich. Previously, he served as Deputy Director of the Institute of Lung Health and Immunity (LHI) and held adjunct faculty positions at the Institute of Lung Health in Giessen, Germany. M.Sc. in Biology and Genetics (University of Vienna, 2004-2008) Ph.D. in Molecular Immunology (Medical University of Vienna, 2008) Postdoctoral training at Max Planck Institute of Biochemistry (2009-2015) His research focuses on extending human healthspan by studying genetic and environmental drivers of chronic lung disease and aging through experimental systems biology and AI-driven approaches. Key areas include: Pulmonary systems biology Regenerative medicine and stem cell biology Extracellular matrix and mechanobiology Single-cell genomics Biology of aging and autoimmune diseases His work emphasizes cross-disciplinary methods like human lung organotypic models and mass spectrometry proteomics. Research trends include lung fibrosis mechanisms, integrin-mediated mechanosensing, and AI applications in chronic disease modeling. Scientific distinctions include: W2 Professorship at LMU Munich Dick Heinegard European Young Investigator Award Helmholtz Young Investigator award German Respiratory Society (DGP) research prize EMBO long term fellowship He has secured research grants from the German Research Foundation (DFG), Chan Zuckerberg Initiative (CZI), and the European Commission. His lab employs cutting-edge single-cell RNA-seq, proteomics, and ex vivo tissue perturbation techniques to elucidate lung disease mechanisms.

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Ryoji AmamotoView profile

Assistant Professor

Harvard UniversityUnited States

Ryoji Amamoto, PhD, is an Assistant Professor of Ophthalmology at Harvard Medical School and an Assistant Scientist at Massachusetts Eye and Ear. His research focuses on retinal degeneration, regenerative neuroscience, and RNA sequencing methodologies. Institution: Harvard Medical School (Massachusetts Eye and Ear) Academic Role: Assistant Professor of Ophthalmology Research Interests: Mechanisms of cone photoreceptor survival in Retinitis Pigmentosa Retinoic acid signaling in ocular development Innovative RNA sequencing techniques (Probe-Seq, FIN-Seq) for cell-type-specific analysis Neuronal regeneration and reprogramming in the central nervous system Scientific Contributions: Developed tools for precise transcriptional profiling of injured or diseased tissues Investigated neurotrophic factors in alcohol consumption models Explored regenerative capacity in adult axolotls and mammalian CNS

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Chen LiView profile

Research Fellow

Monash UniversityAustralia

Dr Chen Li is a Lab Head at the Monash Biomedicine Discovery Institute (BDI), Monash University, where he is affiliated with the Department of Biochemistry and Molecular Biology and contributes to the Cancer and Immunity Programs. He is supported by an ARC Future Fellowship and an NHMRC Ideas Grant, driving research at the intersection of computational biology, proteomics, and immunotherapeutics. Monash Biomedicine Discovery Institute (BDI), Monash University Department of Biochemistry and Molecular Biology ARC Future Fellow NHMRC CJ Martin Early Career Fellow (2018–2022) Visiting Fellow at ETH Zurich Dr Li earned his PhD in Bioinformatics from Monash University in 2016 under the supervision of A/Prof Ashley Buckle and Prof Jiangning Song, focusing on bioinformatics algorithms for protein structure-function analysis. His research spans systems proteomics, immunopeptidomics, cancer, and personalized medicine. He develops computational pipelines integrating multi-omic data—transcriptomics, proteomics, and immunopeptidomics—using machine learning to decode human diseases and support novel immunotherapy development. His work contributes to UN Sustainable Development Goals in health and well-being. The recent publications highlight a strong trend in single-cell genomics, deep learning for chromatin analysis, immunopeptidome mapping in viral and autoimmune contexts, and development of specialized biological databases. These works reflect an integrative, data-driven approach to biomedical discovery. Scientific awards received include: Hans Neurath Outstanding Promise Travel Award (2017) Harnessing systems biology by integrating proteomics and immunopeptidomics to understand prostate cancer (2018) HUPO 2019 Early Career Research (ECR) Travel Award (2019) EMBO Travel Grant (2019) FAOBMB Young Scientist Program Award (2021) Dr Li has secured competitive research grants, including an NHMRC Ideas Grant and a Cure Cancer Australia grant, supporting his work on colorectal cancer neoepitopes and the 'dark immunopeptidome' in type 1 diabetes. He has served as Primary Chief Investigator on multiple projects and actively mentors early-career researchers. His peer-review contributions span journals such as Briefings in Bioinformatics, PLoS ONE, and BMC Bioinformatics. He also engages in public outreach, with media appearances discussing bioinformatics tools and immune system mechanisms. Dr Li leads a dynamic research group at Monash BDI, collaborating with experts in immunology, oncology, and systems biology. His lab integrates computational and experimental approaches, fostering interdisciplinary innovation in biomedicine.

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Ingo EnsmingerView profile

Associate Professor

University of TorontoCanada

Ingo Ensminger is an Associate Professor in the Department of Biology at the University of Toronto Mississauga . His research focuses on plant-environment interactions, particularly in the context of climate science, forest ecology, and molecular physiology of trees. Education : Ph.D. in Plant Physiology from the University of Jena, Germany (2000); Diplom in Plant Physiology from the University of Giessen, Germany (1996). His lab integrates biophysical experiments, molecular biology, next-generation sequencing, and remote sensing to study plant resilience to environmental change. Current projects explore low-temperature acclimation in conifers, drought stress responses, and UAV-based high-throughput phenotyping. Recent work emphasizes trends in remote sensing applications for forest monitoring, including UAV photogrammetry and spectral-temporal analysis. Key collaborations include institutions like Université Laval and Genome Canada. Scientific Awards : Funded by NSERC (Grant RGPIN-2020-06928) and Genome Canada/Quebec/British Columbia for the Spruce-Up Project. Ensminger mentors a diverse team of graduate students and postdoctoral fellows, fostering interdisciplinary research in plant physiology, climate adaptation, and forest carbon dynamics.

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Mercedes PrudencioView profile

Associate Professor

Mayo Clinic College of Medicine and ScienceUnited States

Mercedes Prudencio, Ph.D., is an Associate Professor of Neuroscience at Mayo Clinic in Jacksonville, Florida, where she also holds the position of Associate Consultant II-Research in the Department of Neuroscience. She leads the RNA Metabolism in Neurodegenerative Disease Laboratory, focusing on TDP-43 proteinopathies such as ALS, FTD, and Alzheimer's disease. Her research integrates human biospecimens, animal models, and molecular biology to uncover disease mechanisms and identify biomarkers. University: Mayo Clinic School: Department of Neuroscience Academic Rank: Associate Professor Email: prudencio.mercedes@mayo.edu Dr. Prudencio's research centers on RNA metabolism, particularly the role of TDP-43 in splicing regulation and the implications of its dysfunction in neurodegeneration. A major focus is the truncated stathmin-2 (tSTMN2) transcript, a promising biomarker for TDP-43 pathology. She also investigates neurofilament light and other biomarkers in conditions like SCA3 and post-COVID-19 neurological outcomes. Her work has strong translational potential, aiming to improve clinical trial design and early diagnosis. Her recent publications span high-impact journals such as Nature , Science , and Science Translational Medicine , reflecting her leadership in uncovering cryptic splicing events, protein aggregation, and genetic risk factors in neurodegenerative diseases. These studies reveal consistent themes in TDP-43 dysfunction across ALS, FTD, and AD, highlighting shared molecular pathways. Scientific awards include: Women in Science Travel Fund, The Rockefeller University (2020) Travel Award, American Neurological Association (2019) Outstanding International Student Award, University of Florida (2006–2009) Bryan W. Robinson Endowment Award, Tallahassee Memorial Healthcare (2008) Dr. Prudencio co-leads the Neurological Disease Biorepository and Biomarker Initiative at Mayo Clinic, facilitating collaborative research and grant-funded projects. She is Principal Investigator or Co-PI on multiple grants from the National Institute of Neurological Disorders and Stroke and the ALS Association, supporting research on TDP-43 targets, stathmin-2, and transcriptome biomarkers. Her laboratory serves as a hub for translational neuroscience, bridging molecular discoveries with clinical applications. She is actively involved in mentoring and research training, contributing to postdoctoral fellowships and collaborative networks. Her lab fosters interdisciplinary research, integrating genomics, proteomics, and neuropathology to advance understanding of complex neurodegenerative conditions.

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Tania GendronView profile

Associate Professor

Mayo Clinic College of Medicine and ScienceUnited States

Tania Gendron, Ph.D., is an Associate Professor of Neuroscience at Mayo Clinic in Jacksonville, Florida, where she leads the Translational Neurobiology of ALS and FTD Laboratory. She holds an administrative appointment as Associate Consultant II-Research in the Department of Neuroscience and is actively engaged in cutting-edge research on neurodegenerative disorders. Education: Ph.D. in Cellular and Molecular Medicine, University of Ottawa B.S. in Biochemistry, University of Ottawa Dr. Gendron's research focuses on the molecular underpinnings of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), particularly those linked to the C9orf72 gene mutation. Her laboratory investigates the role of protein aggregates such as TDP-43 and tau, and pioneered the discovery of dipeptide repeat (DPR) proteins as a key pathological feature. A major thrust of her work is biomarker discovery, with significant contributions in establishing poly(GP) DPR proteins and neurofilament light as promising biomarkers for diagnosis, prognosis, and therapeutic monitoring in ALS, FTD, and related disorders. Analysis of her recent publications reveals a consistent focus on neurodegenerative disease mechanisms, with a strong emphasis on C9orf72 pathology, TDP-43 dysfunction, DPR protein toxicity, and the development and validation of fluid-based biomarkers. Her work spans basic molecular mechanisms to translational applications, often utilizing patient-derived tissues and preclinical models. Scientific Awards and Grants: National Institute of Neurological Disorders and Stroke (NINDS) grant as Principal Investigator (PI) for 'c9RAN proteins as a biomarker for C9ORF72-associated ALS and FTD' NINDS grant as PI for 'Core C' project NINDS grant as Co-PI for 'Frontotemporal dementia and related disorders: transcriptomic profiling, biomarker discovery, and mechanistic insight' NINDS grant as Co-PI for 'Pathobiology of Neurodegeneration in C9ORF72 repeat expansion' NINDS grant as Co-PI for 'Poly(ADP-ribose) promotes the condensation and toxicity of C9orf72 arginine-rich dipeptide repeat proteins' Dr. Gendron has secured significant grant funding, indicating national recognition of her research. She actively collaborates with prominent researchers at Mayo Clinic, including Dr. Leonard Petrucelli and Dr. Mariet van Blitterswijk. Her laboratory is a key component of the Neuroscience Research, Discovery, and Translation Labs at Mayo Clinic, contributing to the institution's mission of advancing patient care through innovative research. She has published over 130 peer-reviewed articles and her work has been supported by multiple NIH grants, reflecting a sustained and impactful research program.

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Christopher H. EvansView profile

Professor

Mayo Clinic College of Medicine and ScienceUnited States

Christopher H. Evans, Ph.D., is a Professor at Mayo Clinic College of Medicine and Science, with primary appointments in the Department of Physical Medicine & Rehabilitation and joint appointments in the Department of Orthopedic Surgery and Department of Molecular Medicine at Mayo Clinic, Rochester, Minnesota. He holds the distinguished title of John and Posy Krehbiel Professor of Orthopedics and serves as Director of the Rehabilitation Medicine Research Center and Principal Investigator of the Musculoskeletal Gene Therapy Research Laboratory. John and Posy Krehbiel Professor of Orthopedics (2019) President, Orthopaedic Research Society (2004–2005) Marshall R. Urist, MD Award (2009) Arthur Steindler, MD Award (2010) Honorary Fellow, Swansea University (2009) Dr. Evans’ research leverages gene therapy to develop novel treatments for osteoarthritis and musculoskeletal tissue regeneration. His work spans from basic molecular biology to clinical translation, with a focus on intra-articular gene delivery, bone healing, and cartilage repair. He investigates how inflammatory mediators like IL-1β affect stem cell differentiation and tissue regeneration, aiming to modulate these pathways for therapeutic benefit. The recent publication trends highlight a strong focus on gene therapy for arthritis, particularly using IL-1Ra and BMP-2, as well as innovative approaches like chemically modified RNA and mechanical modulation for bone healing. His studies span preclinical models to human clinical trials, demonstrating a robust translational pipeline. Key themes include chondrocyte senescence, matrix stiffness, epigenetic regulation, and dual-gene delivery systems. Dr. Evans has secured significant research funding, including grants from the National Institute of Arthritis and Musculoskeletal and Skin Diseases and the Congressionally Directed Medical Research Programs. His laboratory actively mentors postdoctoral fellows and collaborates on multidisciplinary projects aimed at improving outcomes in orthopedics and rehabilitation medicine. His lab, the Musculoskeletal Gene Therapy Research Laboratory, is at the forefront of developing single-operation, gene-based therapies for osteoarthritis and non-healing fractures, with the goal of reducing disability and healthcare costs. The lab’s work integrates molecular biology, biomechanics, and clinical research to advance regenerative orthobiologics.

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Debbie Thurtle-SchmidtView profile

Assistant Professor

Davidson CollegeUnited States

Debbie Thurtle-Schmidt is an Assistant Professor in the Biology and Genomics departments at Davidson College. Her research focuses on transcriptional regulation and cellular differentiation in C. elegans , utilizing genomic and genetic approaches to understand how cells develop distinct identities. She can be reached at dethurtleschmidt@davidson.edu or by phone at 704-894-2640. Postdoctoral Studies: University of California, San Francisco (Cellular Molecular Pharmacology) Ph.D.: University of California at Berkeley (Molecular and Cell Biology) B.S.: Santa Clara University (Biology) Dr. Thurtle-Schmidt's work explores genomic regulation in developmental contexts, with particular emphasis on: Transcriptional control mechanisms Epigenetic regulation in cell differentiation Computational analysis of genomic data Environmental influences on gene expression Her recent publications (2020-2024) demonstrate expertise in multi-omics integration , CRISPR technology , and machine learning applications to genomic data, with a focus on C. elegans as a model system. Teaching responsibilities include: BIO 309 Genomics BIO 343 Laboratory Methods in Genomics BIO 240 Biostatistics for Life Scientists BIO/CSC 209 Bioinformatics Programming BIO 115 Molecule, Genes & Cells (+lab) Research is conducted in Wall 325 - Research Lab, with office location at Wall 327.

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Bryan DickinsonView profile

Professor

University of ChicagoUnited States

Bryan Dickinson is a Professor in the Department of Chemistry at the University of Chicago. His research focuses on chemical biology approaches to protein lipidation , synthetic biology , and RNA engineering , with significant contributions to understanding S-acylation dynamics and developing programmable RNA effectors. Key research themes include: Protein-lipid interactions in metabolic diseases RNA-based synthetic biology tools for gene expression manipulation Epitranscriptomic regulation in neurological contexts Novel chemical probes for redox and stress signaling His recent publications (2025-2023) emphasize oxidative stress response , macrocyclic inhibitors , and synaptic RNA regulation . Funding from NIH (R13CA290754, R01EB035016, R01MH122142) supports work on therapeutic development and multidimensional protein interaction analysis. The Dickinson lab employs high-throughput selection systems , split polymerase biosensors , and live-cell imaging to study biochemical pathways in diabetes, neurodegeneration, and cancer.

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Haohan WangView profile

Assistant Professor

Carnegie Mellon UniversityQatar

Haohan Wang is an Assistant Professor at the University of Illinois Urbana-Champaign's School of Information Sciences, with affiliations to the Carl R. Woese Institute for Genomic Biology and the National Center for Supercomputing Applications. His research focuses on developing trustworthy machine learning methods for computational biology and healthcare applications , emphasizing robustness , causality , and interpretability in vision-based models. Recent research trends in his work include: Large Language Model interactions with biomedical challenges (GenoAgent, GenoTex) Adversarial security in language and vision models (Guard, Jailbreakzoo) Genomic data analysis through robust machine learning frameworks (Precision Lasso, Kernel Mixed Models) Interactive toolkits like Robustar for data annotation and model training Scientific awards include recognition as Baidu's Top 50 AI+X Rising Young Scholars (2022), Best Paper Honorable Mention at WSDM 2023, and Broad Institute's Next Generation status (2019). Current projects explore AI-made scientists for biomedical discovery and Robustar development for GUI-based robust vision learning.

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Pal WestermarkView profile

Researcher

Research Institute for Farm Animal BiologyGermany

Pal Westermark is a researcher and Head of the Department of Bioinformatics and Biomathematics at the Research Institute for Farm Animal Biology (FBN) in Dummerstorf, Germany, a position he has held since 2016. He leads the Chronobiology and Bioinformatics Working Group and has previously held research and leadership roles at the Institute of Theoretical Biology, Charité – Universitätsmedizin Berlin. Doctorate (2005): Models of the Metabolism of the Pancreatic β-Cell, KTH Stockholm, Sweden Master's Degree (1999): Molecular Biotechnology, Uppsala University, Sweden His research focuses on circadian rhythms in animals, regulation of gene expression and metabolic pathways, tissue homeostasis, biogerontology, and the application of time series analysis, control theory, and biostatistics to biological systems. He employs mathematical modeling and bioinformatics to understand the dynamics of biological clocks and their impact on metabolism and physiology. The trends in his recent publications reveal a strong focus on circadian biology, particularly in muscle and liver tissues, using transcriptomic, proteomic, and phosphoproteomic approaches. His work integrates computational modeling with experimental data to dissect the mechanisms of circadian regulation, including promoter architecture, rhythmic degradation, and the effects of exercise. He has also contributed methodological tools like the RAIN algorithm and Seagull for analyzing biological rhythms and high-dimensional data. While no specific scientific awards are mentioned in the provided text, his extensive publication record in high-impact journals such as PNAS , PLoS Genetics , and The Journal of Physiology underscores his significant contributions to the field. Dr. Westermark mentors researchers within his working group and leads a research team focused on chronobiology and bioinformatics. His work is supported by institutional funding, though specific grants are not listed. His research program combines theoretical and computational approaches to advance understanding of biological timing systems. He is actively involved in leading the Chronobiology and Bioinformatics Working Group at FBN, which conducts interdisciplinary research at the intersection of biology, mathematics, and computer science. The team develops and applies computational models and bioinformatics tools to study circadian rhythms and their implications for animal and human health.

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Mildred ScheelView profile

Researcher

Julius-Maximilians-Universität WürzburgGermany

Mildred Scheel is a researcher at the University of Würzburg's Medical School, associated with the Mildred Scheel Cancer Research Center (MSNZ). She leads a junior research group investigating the intersection of nuclear RNA metabolism, paraspeckle biology, and genome maintenance in cancer contexts. PhD in Biology (2013, Ludwig Maximilian University of Munich) Postdoctoral research (University of Oxford, 2013-2019) Her work focuses on RNA-binding proteins, long non-coding RNAs like NEAT1, and their roles in DNA damage response and tumorigenesis. Recent publications highlight Dicer dynamics in DNA repair, c-Abl kinase interactions with transcription machinery, and paraspeckle deregulation in cancer. Research interests include: RNA-dependent pathways for genomic stability Mechanisms linking paraspeckles to tumor suppression Role of nuclear bodies in DNA repair Scientific contributions include: 2017 discovery of nuclear phosphorylated Dicer in DNA damage 2018 work on Dicer re-localization following DNA damage 2019 study connecting c-Abl kinase to RNA polymerase II transcription 2021 review on nucleolar lncRNA functions She received a fellowship from the José Carreras Leukemia Foundation during her PhD training (2009-2011). Her group combines molecular cell biology, biochemistry, transcriptomics, and tumor models to unravel paraspeckle dynamics in genome stability.

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