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Richard KimberView profile

Research Fellow

• Environmental Geochemistry
• Nanotechnology
• Bioremediation
• +3 more

Richard Kimber is a Research Fellow at the University of Manchester, holding the Dr Dame Kathleen Ollerenshaw Fellowship in Earth and Environmental Sciences. Previously, he served as a Junior Group Leader at the University of Vienna (2020–2023). His research focuses on two core areas: 1) the environmental fate of nucleic acids, examining how geochemistry influences DNA/RNA stability in contexts like ancient DNA preservation and wastewater epidemiology; and 2) microbial valorisation of metals, developing sustainable methods to convert waste metals into catalytic nanomaterials. His work aligns with UN Sustainable Development Goals related to sustainable production and responsible consumption (SDG 12) and climate action (SDG 13). Kimber earned his PhD in 2013 from the University of Manchester, focusing on the biogeochemical behavior of plutonium and americium in contaminated soils under supervisors Prof. J. Lloyd and Prof. F. Livens. Research Themes: Environmental nucleic acid stability and preservation mechanisms Microbial synthesis of biogenic nanoparticles for industrial applications Metal biorecovery from waste streams using microbial processes Geochemical controls on ancient DNA recovery in sediments Recent Article Trends: Recent work emphasizes nanoparticle synthesis optimization (e.g., Pd and Cu nanoparticles), mercury isotope fractionation studies, and biomolecule-mineral interactions in both terrestrial and extraterrestrial contexts. Over 20 peer-reviewed articles highlight his contributions to environmental geochemistry and sustainable nanotechnology.

Akhil VaidyaView profile

Professor

• Molecular Parasitology
• Antimalarial Drug Development
• Mitochondrial Biology
• +2 more

Akhil Vaidya, PhD, is a Professor in the Department of Microbiology & Immunology at Drexel University College of Medicine, where he also serves as Director of the Center for Molecular Parasitology. He obtained his PhD from the University of Bombay in 1972. His research focuses on understanding the molecular functioning of malaria parasites to develop new antimalarial drugs, with particular emphasis on mitochondrial biology and parasite metabolism. His laboratory investigates essential mitochondrial processes in Plasmodium parasites including electron transport chain function, ATP synthase assembly, and pyrimidine biosynthesis pathways. These studies have led to discoveries of novel drug targets and mechanisms of existing antimalarials like atovaquone/proguanil (Malarone). Dr. Vaidya collaborates internationally on drug discovery projects with Medicines for Malaria Venture, including development of pyrazoleamide compounds that disrupt parasite sodium homeostasis. Research publications demonstrate consistent focus on molecular parasitology, mitochondrial function in apicomplexans, antimalarial drug mechanisms, and parasite metabolism. Recent work explores mitochondrial ribosomal proteins, metabolic roles of endosymbiotic organelles, and transcriptional regulation in Plasmodium. Honors & Awards: Provost Award for Outstanding Scholarly Productivity - Career (2024) Award for Excellence in Basic Science Mentoring (2023) He leads a research team including staff scientists Joanne Morrisey, Michael Mather, and Sudipta Das, and advises graduate students April Pershing, Ming Yang, Lindsay Pomykala, and Suyash Bhatnagar. His work is supported by grants from the NIH and Medicines for Malaria Venture.

Qi LuView profile

Associate Professor

• Nanoparticle-Membrane Interactions
• Biomedical Applications of Nanoparticles
• EEG Analysis of Music Tuning Effects
• +4 more

Dr. Qi Lu is an Associate Professor in the Department of Physics within the Division of Physics, Engineering, Mathematics, and Computer Science at Delaware State University. He holds a Ph.D. in Physics from Clemson University (2006), an M.S. in Physics from Clemson University (2002), and a B.S. in Applied Physics from Shanghai Jiao Tong University (1998). His research focuses on nanoparticle interactions with lipid membranes, optical imaging applications in biomedicine, and the effects of music tuning on brainwaves via EEG analysis. He has co-authored over 15 publications in peer-reviewed journals and contributed to multimodal deep learning and quantum confinement materials design projects. Dr. Lu's expertise spans imaging optics, machine learning, and grant writing. He has secured significant funding including a $431,935 DoD grant (2023-2025) as Co-PI for neuro-pain research and a $799,058 NSF grant (2021-2024) as Co-lead for soft matter and quantum design research. His work bridges nanotechnology with biological systems, particularly exploring how nanoparticles influence membrane structures and potential medical applications. Grants: DoD: Multimodal Deep-Learning for NeuroPain ($431,935, 2023-2025) NSF: SMaRT QD Materials Design ($799,058, 2021-2024) Labs/Teams: Collaborates with the Center of Excellence for Emerging Technologies and the Advanced Quantum Sensing Center at DSU.

Fanny ElahiView profile

Associate Professor

• Vascular Cognitive Impairment (VCID)
• Neurodegenerative Diseases
• Biomarker Discovery
• +7 more

Fanny Elahi is an Associate Professor at the Icahn School of Medicine at Mount Sinai, specializing in vascular cognitive impairment (VCID), neurodegenerative diseases, and biomarker discovery. Her research focuses on neurovascular mechanisms, blood-brain barrier dysfunction, and the development of novel biomarkers using extracellular vesicles and proteomics. She has contributed to studies on Alzheimer’s disease, cerebral small vessel disease, and the impact of systemic factors like atherosclerosis on brain health. Education: Graduated from the Icahn School of Medicine at Mount Sinai (ISMMS) in 2011. Her work integrates clinical neurology with biotechnology, particularly in microfluidics and bioprinting for tissue vascularization. She participates in collaborative projects such as the Clearance of Interstitial Fluid (ISF) and CSF (CLIC) group within the Vascular Professional Interest Area (PIA). Research interests span neuroimmunology, endothelial dysfunction, and the role of inflammation in brain aging. Key themes include sex differences in neurovascular health, retinal imaging as a biomarker for intracranial pathology, and the proteomic analysis of cerebrospinal fluid. Her recent studies highlight the therapeutic potential of targeting complement proteins and the clinical implications of plasma biomarkers like placental growth factor. Publications emphasize longitudinal cohort analyses (e.g., SPRINT-MIND trial follow-up), biomarker validation, and translational approaches in neurodegenerative diseases. She collaborates internationally on CADASIL consortium studies, focusing on early-phase VCID and genetic cerebrovascular diseases.

Sarah SignorView profile

Assistant Professor

• Evolutionary Biology
• Genetics
• Developmental Biology
• +3 more

Sarah Signor is an Assistant Professor in the Department of Biological Sciences at North Dakota State University (NDSU). Her primary research focuses on evolutionary biology, particularly using Drosophila as a model organism to study gene expression evolution, transposable element dynamics, and organismal adaptation to environmental changes. She leads a lab investigating how gene expression evolves within networks, responds to heterogeneous environments, and adapts to human-modified landscapes. Her research spans topics such as transposable element activity in bees, ethanol tolerance in Drosophila , and the evolutionary mechanisms underlying phenotypic plasticity. Key contributions include studies on transposable element invasions, piRNA-mediated defense systems, and genomic analyses of Drosophila species. Signor’s publications reflect a strong focus on molecular and evolutionary genetics, including work on horizontal transfers of transposable elements, sex-biased gene expression, and the genetic basis of adaptation. Her lab emphasizes interdisciplinary approaches, integrating genomic, ecological, and developmental methodologies. While no formal student advisees are listed, her research team actively collaborates on projects involving evolutionary genomics and environmental biology. Grants and funding details are not explicitly mentioned in the provided texts, but her lab’s work suggests sustained research activity in these areas.

Julie A. SaugstadView profile

Researcher

• Cell/Molecular Neurobiology
• Signal Transduction
• MicroRNA
• +3 more

Dr. Julie A. Saugstad is a researcher specializing in Cell/Molecular Neurobiology, focusing on Alzheimer's Disease, Neuroprotection, and the role of MicroRNA and Extracellular Vesicles in neurological processes. She holds a Ph.D. from the University of Oklahoma Health Sciences Center (1991) and completed her postdoctoral fellowship at the Vollum Institute (1991-1996). Dr. Saugstad is actively involved in collaborative research, contributing to advancements in understanding neurodegenerative diseases and extracellular vesicle biology. Education: Ph.D., 1991, University of Oklahoma Health Sciences Center Postdoctoral Fellow, Vollum Institute, 1991-1996 Research Interests: Dr. Saugstad’s work centers on Cell/Molecular Neurobiology , with a focus on Signal Transduction , MicroRNA , and Extracellular Vesicles . Her research explores their roles in Alzheimer’s Disease and strategies for Neuroprotection . Her studies often address sex-specific differences in neurodegenerative processes and the application of biomarkers in clinical diagnostics. Publications Overview: Dr. Saugstad’s recent work includes studies on Alzheimer’s biomarkers, the impact of prenatal THC exposure on neurodevelopment, and the standardization of extracellular vesicle research methodologies. Her contributions span interdisciplinary collaborations, emphasizing reproducibility and translational applications. Awards & Honors: None explicitly mentioned in the provided information. Advising & Grants: While specific grants or student advisement details are not listed, her extensive co-authorship network suggests active participation in collaborative research projects, likely involving grant-funded initiatives. Labs & Collaborations: Engaged with the International Society for Extracellular Vesicles. Her work often involves interdisciplinary teams, as reflected in co-authorships with institutions such as Oregon Health & Science University and the University of Miami.

Indranil MukhopadhyayView profile

Professor

• Biostatistics
• Statistical Genetics
• Genomics
• +3 more

Indranil Mukhopadhyay serves as a Professor in the Department of Statistics at the University of Nebraska-Lincoln, where he conducts cutting-edge research at the intersection of statistics, genomics, and public health. His work bridges theoretical statistical methodology with urgent real-world health challenges, particularly in infectious disease modeling and genomic data analysis. His primary research interests encompass biostatistical methodology development for multi-omics integration, epidemiological modeling of infectious diseases (notably HIV/AIDS and COVID-19), and statistical genetics for complex trait analysis. He has pioneered robust computational frameworks for handling high-dimensional biological data, with emphasis on isoform quantification, gene expression clustering, and genetic association studies in diverse populations. Analysis of his recent publications reveals a strong trajectory toward public health applications , where statistical models directly inform pandemic response strategies and disease control policies. His work consistently demonstrates innovation in adapting mathematical frameworks (e.g., critical community size theory) to contemporary health crises, while maintaining rigorous methodological foundations in sequential estimation and robust statistics. No scientific awards were documented in the provided materials. Information regarding student advising, research grants, or laboratory infrastructure was not available in the source text. His publication record suggests active collaboration with medical researchers, particularly in studies involving Indian population cohorts and rare genetic disorders. No details about specific research laboratories or collaborative teams were provided in the available documentation.

Christine BeuckView profile

Assistant Professor

• Nuclear Magnetic Resonance (NMR) Spectroscopy
• Protein Interactions
• Structural Biology
• +3 more

Dr. Christine Beuck is an Assistant Professor at the University of Duisburg-Essen, affiliated with the Faculty of Biology and the Centre for Medical Biotechnology (ZMB). Her research focuses on structural and medicinal biochemistry, particularly using Nuclear Magnetic Resonance (NMR) spectroscopy to study protein interactions and supramolecular ligand binding. She is a key member of the Collaborative Research Center (CRC) 1093, investigating protein interactions with synthetic ligands and their biological implications. Education: She earned a Diploma in Chemistry from TU Dortmund (2001) and a Ph.D. in Chemistry from RWTH Aachen University (2005) under Prof. E. Weinhold. Postdoctoral training included work at The Scripps Research Institute (2005–2014) under Prof. J. R. Williamson, followed by a Japan exchange program at Tokyo University (2005) and a Lithuania exchange at the Institute of Biotechnology (2003). Research Interests: Her work combines NMR spectroscopy with biochemical techniques (e.g., fluorescence, ITC, BLI) to analyze protein-ligand interactions, protein structures, and dynamics. She pioneered side-chain-specific NMR experiments for lysine/arginine residues and employs advanced NMR methods like BEST-TROSY for large proteins. Applications span drug design, understanding disease-linked protein dysfunctions, and nanotechnology (e.g., gold nanoparticle characterization). Advising & Grants: While specific grants are not detailed, her CRC 1093 affiliation indicates collaborative funding. Her research contributes to developing supramolecular ligands to modulate biological interactions, with potential medical and biotechnological applications. Labs/Teams: She leads projects in the ZMB and collaborates with institutions worldwide, including The Scripps Research Institute and Tokyo University. Her lab integrates structural biology, medicinal chemistry, and nanotechnology to address complex biological questions.

Simon MoxonView profile

Associate Professor

• Bioinformatics
• Gene Regulation
• Next-Generation Sequencing
• +3 more

Simon Moxon is an Associate Professor in Bioinformatics at the University of East Anglia (UEA), part of the School of Biological Sciences. His research focuses on applying next-generation sequencing (NGS) technologies to study biological problems, particularly small RNA bioinformatics and mechanisms of gene regulation at transcriptional and post-transcriptional levels. He has developed tools like miRCat2 and the UEA sRNA Workbench for miRNA detection and analysis. Notable collaborations include projects funded by the British Heart Foundation, NIH, and the Natural Environment Research Council, exploring topics such as chromatin landscapes, microRNA biogenesis, and epigenetic reprogramming. His work spans plant genomics, developmental biology, and molecular mechanisms in diseases like cancer. Recent publications highlight advancements in understanding miRNA regulation in plants and animals, epigenetic marks during zygotic reprogramming, and antimicrobial resistance in Bacillus species. Moxon actively mentors PhD students and contributes to editorial roles in journals like Frontiers in Molecular Biosciences.

• Chromatin Regulation
• Stem Cell Biology
• Epigenetics
• +3 more

Thomas Fazzio is a Professor at the University of Massachusetts Chan Medical School, affiliated with the T.H. Chan School of Medicine and multiple departments including Molecular, Cell and Cancer Biology, Biochemistry and Molecular Biotechnology, and Systems Biology. He holds additional roles in graduate programs at the Morningside Graduate School of Biomedical Sciences. His research focuses on chromatin regulation in stem cells, cancer biology, and developmental epigenetics. Education and Training: B.S. in Biology, University of Utah (1997) Ph.D. in Molecular & Cellular Biology, University of Washington and Fred Hutchinson Cancer Research Center (2004) Postdoctoral work at University of California, San Francisco (2004–2010) Research Interests: Thomas's lab investigates how chromatin structure influences gene expression and cell fate in embryonic and cancer stem cells. Key projects include studying the Tip60-p400 chromatin remodeling complex, chromatin dynamics during differentiation, and epigenetic mechanisms in cancer stem cells. Techniques used include molecular biology, genomics, and systems-level approaches. Publications: His recent work highlights novel insights into chromatin packaging in sperm (2023), EZH2 inhibition in pancreatic cancer (2023), and EXOC2's role in ALS/FTD (2024). Research trends emphasize multi-omics profiling and epigenetic regulation in disease contexts. Awards: Jane Coffin Childs Memorial Fund Fellowship (Postdoctoral) NIH Pathway to Independence Award Advising & Labs: Offers rotation projects on chromatin regulators, Tip60-p400 mechanisms, and cancer stem cells. Active postdoc positions are available. Collaborations include work with Oliver Rando and Lihua Zhu on chromatin profiling techniques. Labs/Teams: His lab integrates computational and experimental approaches to study dynamic chromatin landscapes, with a focus on translational applications in cancer and regenerative medicine.

Nessly CraigView profile

Associate Professor

• Molecular Biology
• Biochemistry
• Gene Expression Regulation
• +3 more

Nessly Craig is an Associate Professor in the Department of Biological Sciences at the University of Maryland, Baltimore County (UMBC). His research focuses on the biochemical and molecular mechanisms of precursor ribosomal RNA processing in eukaryotic cells. He holds a B.A. from Reed College (1963), a Ph.D. from the University of Pennsylvania (1967), and completed postdoctoral training at the Institute for Cancer Research (1970). His laboratory investigates nucleic acid sequences, RNA structural motifs, and enzymatic components involved in rRNA processing regulation. Key questions include cleavage site specificity, enzyme requirements, and regulatory links to ribosome production in intact cells. Courses taught include advanced molecular biology, cell biology, and honors thesis supervision. Publications highlight contributions to understanding rRNA maturation pathways, structural motifs, and comparative processing mechanisms across species. His work integrates molecular biology techniques to uncover foundational aspects of eukaryotic gene expression.

Marius SchmidtView profile

Professor

• Biophysics
• Structural Biology
• Macromolecular Crystallography
• +3 more

Marius Schmidt is a Professor of Physics at the University of Wisconsin-Milwaukee (UWM), affiliated with the Biophysics Faculty. He holds a Dipl. in Biology from Johannes-Gutenberg-University, Mainz (1990), a Dr. rer. Nat. in Experimental Physics from Technische Universität München (1996), and habilitations in Experimental Physics (2004) and Theoretical, Physical, and Analytical Chemistry (2008). His research focuses on applying physical methods to study biological molecules, particularly using static and time-resolved macromolecular crystallography to investigate protein structure, dynamics, and kinetics. He also develops software for analyzing time-resolved X-ray data and employs spectroscopic methods to corroborate findings. From 1996–2007, Schmidt held positions at Technische Universität München and the University of Chicago before joining UWM in 2007. His work has led to groundbreaking studies on protein dynamics, including femtosecond observation of conical intersections and structural analysis of phytochrome photocycles. His research leverages cutting-edge technologies like X-ray free electron lasers (XFEL) to capture molecular processes at unprecedented speeds and resolutions. Key contributions include structural enzymology studies, membrane protein analysis at XFEL facilities, and the development of mix-and-inject serial crystallography techniques. Despite no explicitly listed awards, his publications reflect significant contributions to biophysics and structural biology. His advising and grants are not detailed in the text, though collaborations with institutions like the University of Chicago and international XFEL facilities suggest extensive network engagement. His affiliation with UWM’s Biophysics Faculty emphasizes interdisciplinary research bridging physics and biology.

Dan FabrisView profile

Professor

• Nucleic Acids
• RNA Viruses
• HIV
• +3 more

Dan Fabris is the Harold S. Schwenk Sr. Distinguished Chair in Chemistry Education at the University of Connecticut's Department of Chemistry. He leads an active research laboratory focused on nucleic acids and their role in infectious diseases. His lab joined UConn in January 2020 and has been steadily growing with multiple new members joining through 2024. Dr. Fabris received his Ph.D. from the University of Padova (Italy) and completed postdoctoral training at the University of Maryland Baltimore County and at the National Research Council in Padova, Italy. His research program investigates structure-function relationships in nucleic acids and protein-nucleic acid complexes that play determinant roles in infectious diseases, with an overarching goal to identify therapeutic targets for HIV, hepatitis C, Zika, and other RNA viruses. His research interests span across nucleic acid biochemistry, virology, and drug discovery. Dr. Fabris employs a cross-disciplinary approach that combines biophysical, biochemical, computational, and omics techniques with novel mass spectrometry technologies developed in his laboratory. His work particularly focuses on regulatory mechanisms of viral processes involving RNA post-transcriptional modifications (PTMs) and their role in mediating the potentiating effects of drugs of abuse on HIV-1 replication. Analysis of Dr. Fabris's recent publications reveals a consistent focus on RNA structure and function, particularly in the context of HIV. His work leverages mass spectrometry techniques to investigate RNA-protein interactions, with special emphasis on TAR RNA and the HIV-1 nucleocapsid protein. His research spans from fundamental structural studies to applied drug discovery, with multiple publications on small molecule inhibitors targeting viral RNA elements. UConn Waring Award (awarded to Daniele Rollo, a student in his lab) UConn Masterton-Hurley Teaching Award (awarded to Sarah Mutchek, a teaching assistant in his lab) Patent awarded to Dan Fabris and lab alumni Rebecca Rose Dr. Fabris actively mentors numerous graduate students and researchers. His lab has welcomed multiple new members in recent years, including Rumbie Chitongo, Joshua Albarracin, Hein Htet, Sienna Brigance, Margrate Anyanwu, Sofia Pezzotti, Alexander Steinberg, Michael Addo, Derek Bobowick, Cole Angell, and Sabrina Daigle. Several of his former students have successfully defended their dissertations (Thomas Kenderdine, Limin Deng) and moved on to positions at Yale School of Medicine (Jyotsna Kumar, Swapna Naik) and Pfizer (Ghazaleh Yassaghi). The lab is equipped with advanced instrumentation including an FT-ICR mass spectrometer delivered in October 2020.

Tero AholaView profile

Senior Lecturer

• Virology
• RNA Replication
• Antiviral Research
• +5 more

Tero Ahola is a Senior University Lecturer at the University of Helsinki, affiliated with the Department of Microbiology within the Faculty of Agriculture and Forestry. His research focuses on RNA virus replication mechanisms, antiviral strategies, and host-pathogen interactions. He is actively involved in doctoral supervision and editorial roles in virology journals. Research Interests: Virology RNA Replication Factories Alphavirus Biology Host Cell Membrane Remodeling Antiviral Drug Development Host-Targeted Inhibition Advising & Grants: Supervised doctoral students including Aditya Thiruvaiyaru and Tania Quirin Leading projects such as 'Host cell factors as antiviral targets' (2024–2028) funded by the Academy of Finland Recipient of grants from private foundations and governmental bodies Labs/Teams: Member of the Helsinki One Health Research network, collaborating on interdisciplinary virology initiatives.

Trine Eker ChristoffersenView profile

Researcher

• Molecular Biology
• Biochemistry
• Microbiology
• +7 more

Trine Eker Christoffersen is the Acting Pro-Rector for Research and Director of Research at Østfold University College , holding strategic leadership roles from 2024 to 2025. She has a PhD in Biochemistry from the University of Oslo and holds higher degrees from Imperial College London and the University of Leeds. Education PhD, Biochemistry, University of Oslo (2007) MSc, Biochemical Research, Imperial College London (1999) BSc (Hons), Biotechnology, University of Leeds (1997) BSc, Chemical Engineering, Østfold University College (1995) Her research focuses on cell biology, microbiology, and immunology , particularly on bacteria-host interactions, probiotics, and intracellular signaling . She has contributed to understanding how non-commensal bacteria affect intestinal immunity and the functional diversity of growth factors. While her recent articles trend toward probiotic mechanisms, intestinal health, and cellular interactions , she also explores educational innovation and medical biochemistry . Her work includes collaborations with institutions like the University of Sydney and the University of Oslo. She leads initiatives in institutional research strategy and serves on committees like the Central PhD Committee and the Research Ethics Advisory Board.