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Alexandre Bouchard-Côté is a Professor of Statistics at the University of British Columbia (UBC), affiliated with the Department of Statistics within the Faculty of Science. His research focuses on computational statistics, Bayesian methods, and Monte Carlo techniques, with applications in evolutionary biology, cancer genomics, and computational linguistics. Education : PhD in Computer Science (with Designated Emphasis in Statistics) from UC Berkeley (2010), BSc in Mathematics and Computer Science from McGill University (2005). Affiliations : Director of the Blang probabilistic programming project and leader of the Bouncy Particle Sampler research group. Research Interests : Bouchard-Côté develops scalable Bayesian computational methods, including non-reversible Monte Carlo algorithms like the Bouncy Particle Sampler, and applies these to problems in cancer phylogenetics, evolutionary dynamics, and historical linguistics. His work emphasizes bridging theoretical foundations with practical tools for data science. Publications Trends : Recent work spans distributed sampling frameworks (e.g., Pigeons.jl), variational phylogenetic inference, and cancer clonal evolution modeling. His articles often address algorithmic scalability and interdisciplinary applications in biology and astronomy. Awards : CRM-SSC Prize in Statistics (2024) PIMS-UBC Mathematical Sciences Young Faculty Award (2018) Tweedie New Researcher Award (2016) Advising & Grants : Supervises graduate students (e.g., Son Luu, Nikola Surjanovic) and leads funded projects on distributed MCMC and cancer genomics. Collaborates with institutions like the Simons Foundation and the Canadian Statistical Sciences Institute (CANSSI). Labs/Teams : Core member of the UBC Statistical Machine Learning group, contributing to open-source tools like Blang and the Bouncy Particle Sampler implementation.

• Computational Statistics
• Bayesian Inference
• Monte Carlo Methods
• +4 more

Jörg Bohlmann is a Professor in the Department of Forest and Conservation Sciences at the University of British Columbia , affiliated with the Michael Smith Laboratories, Botany Department (Faculty of Science), and Wine Research Centre. His research spans genomics, biochemistry, and chemical ecology of plant specialized metabolism, focusing on terpenoids and phenolics for applications in forest health and bioproducts. Research Streams : Plant defense against insects/pathogens, metabolic engineering of bioproducts, forest genomics, and molecular evolution of terpenoid pathways. Collaborations : National and international partnerships with academia, government, and biotech industries. Recent Publications highlight genomic insights into Western Redcedar (2023), including its low genetic diversity and adaptation mechanisms despite self-fertilization. Earlier work (2001–2022) covers conifer defense systems, Arabidopsis terpenoid pathways, cannabis flavor genetics, and mass spectrometry infrastructure. Scientific Awards include: NSERC E.W.R. Steacie Fellow (2015), Fellow of the Royal Society of Canada (2015), Feodor Lynen Postdoctoral Fellowship (1995–1998), and Distinguished University Scholar (UBC). Funding Sources : NSERC (Discovery/Strategic grants), CFI, Genome Canada/BC, provincial/federal agencies. Labs & Facilities : Michael Smith Laboratories (UBC), National Centre of Excellence, Forest Sciences Centre, and a dedicated mass spectrometry lab for metabolite analysis.

• Plant Defense Mechanisms
• Terpenoid Biochemistry
• Forestry Genomics
• +12 more

Thibault Mayor is a Professor in the Department of Biochemistry and Molecular Biology and the Michael Smith Laboratories at the University of British Columbia (Vancouver). His research focuses on understanding how cells manage misfolded proteins, with implications for neurodegenerative diseases like Parkinson's and Alzheimer's. He holds academic affiliations with the Centre for High-Throughput Biology (CHiBi) and has been recognized with awards including the UBC Killam Teaching Award (2020). Education: BSc, University of Geneva, Switzerland (1997) PhD, University of Geneva & Max Planck Institute of Biochemistry, Germany (2001) Postdoctoral Fellow, California Institute of Technology (2002) Research Interests: Mayor's lab investigates protein homeostasis, ubiquitin-proteasome system dynamics, and the molecular mechanisms underlying protein aggregation in aging and disease. Projects include proteomic approaches to identify aggregation-prone proteins and develop microbial cell factories for protein production. Grants & Awards: CIHR Project Grant ($730K, 2018) Michael Smith Foundation Career Award (2012) UBC Killam Teaching Award (2020) Labs & Collaborations: The Mayor Lab is part of the Michael Smith Laboratories and collaborates with computational biologists like Jörg Gsponer. They maintain active partnerships in proteomics and systems biology, contributing to initiatives like the BC Proteomics Network.

• Protein Homeostasis
• Ubiquitin Proteasome System
• Neurodegenerative Diseases
• +7 more

Dr. Muhammad Abdul-Mageed is an Associate Professor in the School of Information at The University of British Columbia, with joint appointments in Linguistics and an associate membership in Computer Science. He holds the Canada Research Chair in Natural Language Processing and Machine Learning. His research focuses on deep learning, socio-pragmatics, and speech/language technologies, particularly for Arabic and African languages. He leads the UBC Deep Learning & NLP Group and co-directs SSHRC-funded grants like I Trust AI and Ensuring Full Literacy. He is a founding member of the Center for Artificial Intelligence Decision making and Action and a member of the Institute for Computing, Information, and Cognitive Systems. His work spans automatic speech recognition, machine translation, computational socio-pragmatics, and low-resource language technologies. Notable projects include developing Arabic speech recognition systems, multidialectal Arabic benchmarks, and tools for African language processing. He has authored over 100 peer-reviewed papers and leads initiatives like the NADI Arabic Dialect Identification shared task and the NileChat project for culturally-aware LLMs. His research aims to create equitable, socially-aware AI systems for health, social media, and information management.

• Natural Language Processing
• Deep Learning
• Socio-Pragmatics
• +5 more

Dr. Lourdes Pena-Castillo is a Professor jointly appointed in the Departments of Computer Science and Biology at Memorial University of Newfoundland's Faculty of Science. Her research focuses on applying machine learning and bioinformatics to study bacterial gene regulation, with emphasis on transcriptomics, gene expression pathways, and microbiology. She leads the Bioinformatics Lab at MUN, developing computational tools like Promotech for promoter prediction and sRNARFTarget for sRNA target identification. Education: BSc in Information Systems Engineering, ITESM-Mexico MSc in Computer Science, University of Alberta PhD in Computer Science (Doktoringenieurin), Otto-von-Guericke Universität Magdeburg Postdoc in Bioinformatics, University of Toronto Research Interests: Bioinformatics, Genomics, Machine Learning, Artificial Intelligence, Transcriptomics, Gene Regulation, Microbiology Her work integrates computational methods with biological data to address challenges in molecular biology, including analyzing bacterial sRNA functions, promoter recognition, and disease diagnostics using machine learning. She has advised numerous graduate students, including PhD candidates Purvikalyan Pallegar and Bonita McCuaig, and MSc students like Ruben Chevez-Guardado and Kratika Naskulwar. Her lab focuses on translational research with applications in both basic science and clinical contexts. Publications span computational methods for bacterial gene regulation, bioinformatics tool development, and interdisciplinary projects in VR and healthcare informatics. Her research has contributed to understanding symbiotic relationships in marine organisms, inflammatory bowel disease diagnostics, and clavulanic acid production in Streptomyces. Grants & Collaborations: Works with interdisciplinary teams across computer science and biology, supported by grants enabling projects in bacterial genomics and computational tool development. Labs & Teams: Leads the Bioinformatics Lab at MUN, fostering collaborations with researchers in microbiology, computer science, and healthcare.

• Bioinformatics
• Genomics
• Machine Learning
• +5 more

Christopher M. Overall is a Full Professor at the University of British Columbia in the Faculty of Dentistry, Department of Oral Biological and Medical Sciences . He is also a Principal Scientist at the Centre for Blood Research and holds associate memberships in UBC's Biochemistry & Molecular Biology , Obstetrics and Gynecology , and Bioinformatics Graduate Program departments. As a Canada Research Chair Laureate , he pioneered the field of degradomics to study proteases in vivo. B.D.S., University of Adelaide Ph.D., University of Toronto Postdoctoral Fellowship, UBC (with Nobel Laureate Michael Smith) Dr. Overall’s research focuses on protease proteomics and systems biology , particularly degradomics to analyze protease substrates in diseases like COVID-19 and immunodeficiency . His work on matrix metalloproteinases has revealed new therapeutic strategies for inflammatory diseases and cancer . His 15 most recent articles (2015–2008) demonstrate expertise in TAILS proteomics , protein terminomics , and protease network analysis with applications in arthritis , antiviral immunity , and precision medicine . Scientific Awards 2022 Helmut Holzer Award 2018 Royal Society of Canada Fellow 2014 Tony Pawson Canadian Proteomics Award 2013 IADR Distinguished Scientist Award Dr. Overall has mentored 61 trainees , including 9 full professors with department chairs, and received the UBC John McNeill Mentorship Award (2023). He leads the HUPO Chromosome-centric Human Proteome Project and consults for Genentech and Novartis .

• Protease Proteomics
• Systems Biology
• Degradomics
• +6 more

David Vocadlo is a Distinguished Professor of Chemistry and Molecular Biology & Biochemistry at Simon Fraser University (SFU), holding the Canada Research Chair in Chemical Biology. His research focuses on Chemical Glycobiology, investigating carbohydrate-processing enzymes and developing chemical tools to study glycan roles in health and disease. His lab explores O-GlcNAc signaling, neurodegenerative disorders (e.g., Alzheimer’s, Parkinson’s), and enzyme inhibitors for therapeutic applications. Education: PhD from University of British Columbia (UBC), followed by a CIHR postdoctoral fellowship at UC Berkeley. Key roles include E.W.R. Steacie Memorial Fellow and Royal Society Fellow. Research highlights include O-GlcNAcase inhibitors for neuroprotection, glycan structure-function relationships, and enzyme activity imaging tools. Collaborates globally with experts in glycobiology and employs cutting-edge techniques like chemical synthesis, mass spectrometry, and live-cell imaging. Awards: Distinguished Professor title, Canada Research Chair, Royal Society Fellowship. Active in training researchers through SFU’s graduate programs, emphasizing interdisciplinary approaches. Lab members work on topics ranging from enzyme mechanisms to disease modeling.

• Bioorganic Chemistry
• Chemical Biology
• Glycobiology
• +3 more

Sachdev Sidhu is a Research Professor and Entrepreneur in Residence at the University of Waterloo. His research focuses on synthetic antibodies, protein engineering, and biotechnological applications. He leads efforts in developing novel therapeutic antibodies, engineered protein systems, and molecular tools for biomedical research. His work spans cancer therapy, viral infection countermeasures, and regenerative medicine. Sidhu is also involved in translational research, bridging academic discoveries with commercial applications through entrepreneurial ventures. Key research interests include synthetic antibody libraries, CAR T-cell engineering, ubiquitin-based therapeutics, and phage display technologies. He has contributed to advancements in targeted therapies for glioblastoma, leukemia, and ocular diseases. His team develops innovative methods for protein design, such as engineered ubiquitin variants and modular antibody architectures. Publications highlight breakthroughs in antibody-based treatments, including synNotch CAR T cells for glioblastoma and neutralizing antibodies against SARS-CoV-2. His work integrates structural biology, molecular biology, and computational approaches to address complex biomedical challenges. Sidhu collaborates with industry partners to advance technologies into clinical and commercial settings.

• Synthetic Antibodies
• Protein Engineering
• Biotechnology
• +5 more

Joel Weadge is an Associate Professor in the Biology Department at Wilfrid Laurier University , Waterloo, Ontario. His research focuses on bacterial biofilms, glycobiology, and protein structure-function relationships. Contact: jweadge@wlu.ca , Office: BA425 (Bricker Academic). Education: PhD in Microbiology (University of Guelph, 2006) BSc (Hons) in Microbiology (University of Guelph, 2000) Research Interests center on bacterial biofilms as virulence factors in pathogens like E. coli and Salmonella . Key areas include: Structural and functional characterization of biofilm proteins (cellulose, curli fimbriae) Enzymology of carbohydrate modifications (acetylation, phosphoethanolamine transfer) Developing therapeutics targeting biofilm synthesis Biopolymer applications for medical/industrial use Publications highlight studies on Pseudomonas and Salmonella biofilm mechanisms, glycosyltransferases, and carbohydrate-active enzymes, with methodologies spanning X-ray crystallography to high-throughput biofilm profiling. Labs and Teams: The Weadge Lab investigates biofilm roles in food/water security and oral health, utilizing enzymology, mass spectrometry, and structural biology. Current members include graduate students, technicians, and research assistants.

• Bacterial Biofilms
• Bacterial Carbohydrates
• Protein Structure and Function
• +7 more

Dr. Anil Kumar is an Assistant Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan's College of Medicine. He specializes in molecular virology, focusing on positive-stranded RNA viruses and their interactions with host immune systems. His research employs high-throughput genetic screens and reverse genetics systems to identify host factors critical for viral infection. Education includes a BSc in Agricultural Sciences (1999, Kerala Agricultural University), MSc in Plant Pathology (2001, Indian Agricultural Research Institute), and PhD in Molecular Virology (2010, University of Heidelberg). Postdoctoral training included stints at the University of Heidelberg (2010–2013) and the University of Alberta (2014–2020). Research interests center on Eastern Equine Encephalitis virus (EEEV) and Enterovirus D68 (EV-D68). For EEEV, his lab investigates immune evasion mechanisms and host-virus protein interactions to identify therapeutic targets. For EV-D68, they study CNS invasion mechanisms and novel host dependency factors linked to acute flaccid myelitis (AFM). Recent work includes studies on SARS-CoV-2, uncovering roles for host proteins like Argonaute 2 in viral restriction. His lab integrates molecular biology, virology, and systems biology approaches, with a focus on translational research for antiviral drug development. Collaborations include work on respiratory syncytial virus (RSV) entry mechanisms and dengue virus replication regulation.

• Molecular Virology
• Virus-host Interactions
• Innate Immune Response
• +3 more

Brent Page is an Associate Professor (tenured) in the Faculty of Pharmaceutical Sciences at the University of British Columbia (UBC) and maintains a research group at the Karolinska Institute , Department of Oncology and Pathology. His dual affiliation underpins a trans-Atlantic program that integrates cutting-edge chemical biology with medicinal chemistry for anti-cancer drug discovery. Education & Training PhD in Chemistry – University of Toronto (2013) HBSc in Chemistry (Honours) – University of British Columbia (2008) CIHR Postdoctoral Fellow – Karolinska Institute, Sweden (2008–2016) Assistant Professor (non-independent) – Karolinska Institute, Department of Oncology-Pathology (2017–2021) Research Focus Dr. Page’s laboratory operates at the interface of medicinal chemistry and chemical biology , aiming to identify and optimize small-molecule inhibitors for proteins previously considered “undruggable.” Core targets include STAT3, CLIC3, NUDT5/15 and SRPK3 . The group employs cellular thermal shift assays , isothermal ligand-induced resolubilization (ILIRA) , and CeTEAM technologies to quantify target engagement and refine structure–activity relationships in physiologically relevant models of breast cancer, triple-negative breast cancer, leukemia and atopic diseases . Funding & Collaborations His program is supported by Canadian Institutes of Health Research (CIHR) and other national and international agencies. Dr. Page actively participates in UBC’s Accelerated Translational Opioid Research Cluster and welcomes interdisciplinary collaborations and undergraduate research involvement. Equity, Diversity & Inclusion Committed to fostering an inclusive environment, Dr. Page mandates EDI training for all lab members and actively encourages participation from equity-deserving groups.

• Medicinal Chemistry
• Chemical Biology
• Drug Discovery and Development
• +13 more

Dr. Jacques Archambault is a Professor in the Department of Microbiology and Immunology at McGill University , and an associate member of the Division of Experimental Medicine since 2016. His research focuses on the molecular biology and pathogenesis of human papillomaviruses (HPVs) and polyomaviruses (HPyVs), with an emphasis on their replication mechanisms as episomes in host cells. The Archambault laboratory employs functional genomics, proteomics, and chemical biology approaches to identify cellular pathways exploited by these viruses and develop high-throughput assays for screening small molecule inhibitors of viral replication. Analysis of his recent publications reveals a strong focus on HPV and HPyV replication machinery, including studies on the E1 helicase, UAF1-USP1 interactions, and structural characterization of viral proteins involved in DNA replication. His work bridges virology, oncology, and drug discovery, particularly targeting oncogenic HPV types implicated in anogenital and oropharyngeal cancers, as well as HPyVs like BKPyV and JCPyV that cause pathologies in immunosuppressed patients. Current efforts in the lab aim to elucidate the molecular mechanisms by which HPVs and HPyVs replicate their genomes and to develop antiviral therapies targeting these processes. Techniques such as fluorescence anisotropy, NMR spectroscopy, and crystallography are frequently employed to study protein-DNA and protein-protein interactions critical to viral replication.

• Human Papillomavirus (HPV)
• Polyomavirus
• Viral DNA Replication
• +4 more

Hong Han is an Assistant Professor in the Department of Biochemistry & Biomedical Sciences within McMaster University's Faculty of Health Sciences and a member of the Centre for Discovery in Cancer Research (CDCR). She holds a Canada Research Chair and leads the Han Lab, which focuses on cancer biology, RNA regulation, and innovative high-throughput technologies for therapeutic discovery. Dr. Han earned her Ph.D. from the University of Toronto (2010-2016) and has established herself as a leading researcher in glioblastoma and alternative splicing regulation. Her interdisciplinary research integrates cancer biology, RNA science, and multilayer gene regulation to uncover mechanisms underlying cancer progression and treatment resistance. Her laboratory pioneers integrated technological platforms for large-scale genetic/drug screening and ultra-high-throughput single-cell profiling. The research focuses on three main areas: alternative splicing regulation in cancer (particularly glioblastoma and prostate cancer), multilayer mechanisms of glioblastoma heterogeneity and microenvironment evolution, and multiplexed screening approaches for therapeutic discovery in treatment-resistant cancers. Analysis of Dr. Han's recent publications reveals a strong emphasis on single-cell technologies to characterize glioblastoma heterogeneity, minimal residual disease states, and tumor-immune interactions. Her work increasingly bridges basic RNA biology with translational applications, particularly in developing novel therapeutic strategies targeting splicing networks and immune evasion mechanisms. Canada Research Chair Dr. Han teaches Advanced Techniques in the Biomedical Sciences (BIOCHEM 734). Her research program is supported by multiple funding sources, as evidenced by her extensive publication record in high-impact journals including Nature, Cell, Molecular Cell, and Nature Communications. She employs a comprehensive approach combining in vitro, in vivo, and patient cohort studies with cutting-edge genomic technologies. The Han Lab has developed innovative multiplexed screening platforms that enable simultaneous interrogation of thousands of conditions, ranging from CAR-T cells to small molecule therapeutics. This approach accelerates the discovery of novel cancer targets and therapeutic strategies for treatment-resistant cancers.

• Cancer Biology
• Gene Regulation
• RNA Splicing
• +5 more

Geoffrey Tranmer is a Tenured Associate Professor in the College of Pharmacy at the University of Manitoba. His research integrates medicinal chemistry, drug discovery, and synthetic organic methodologies, with a focus on flow chemistry and targeted cancer therapies. NSERC Post-Doctoral Fellow, University of Cambridge Post-Doctoral Fellow, Princeton University PhD in Organic Chemistry, University of Guelph BSc (Hons) in Chemistry, Brock University His research explores: Development of flow chemistry techniques to enhance synthetic organic methods Lead generation and optimization in drug discovery Bioconjugation strategies for chemical biology applications Targeted cancer therapies leveraging hypoxia-activated prodrugs Recent publications highlight his work in neurodegenerative disease drug design, biomarker discovery, and sustainable synthesis technologies. Scientific Awards CIHR Project Grant (2024-2029) NSERC Discovery Grant (2023-2028) CIHR Bridge Grant (2022) NSERC Alliance Grant (2020) NSERC Engage Grant (2017) Research Manitoba New Investigator Operating Grant (2017) Dr. Tranmer's industrial experience at Merck Frosst and academic leadership at Manitoba position him uniquely to bridge chemistry-biology-industry collaborations. His lab actively trains graduate students in cutting-edge synthesis platforms.

• Medicinal Chemistry
• Drug Discovery
• Organic Synthesis
• +4 more

Gabriela V. Cohen Freue is an Associate Professor in the Department of Statistics at the University of British Columbia (UBC), Vancouver Campus, and holds a Canada Research Chair (CRC Tier 2). She leads an interdisciplinary research program focusing on developing robust statistical methodologies for analyzing high-dimensional data in genomics and proteomics, with applications in medical sciences. Her work addresses challenges such as outliers, collinearity, and measurement errors, with applications in biomarker discovery for diseases like multiple sclerosis, cardiovascular disorders, and asthma. Her academic journey includes collaborations across disciplines, including with the BC Cancer Agency, PROOF Centre of Excellence, and iCAPTURE. She has pioneered methods like the Penalized Elastic Net S-Estimator (PENSE) and contributed to proteomic data analysis tools such as the Protein Group Code Algorithm (PGCA). She also co-developed the MDQC quality control method for microarrays. Research interests include robust regression, biomarker development, and statistical methods for big data. Her team includes postdocs, PhD, and MSc students, with a focus on training in both statistical rigor and interdisciplinary collaboration. Notable grants include a CANSSI Collaborative Research Team Project (CRT) award for robust causal inference and prediction modeling. Teaching responsibilities span statistical consulting, high-dimensional biological data analysis, and generalized linear models. She emphasizes active learning and real-world problem-solving in her courses. Her lab’s work is supported by grants from the Data Science Institute (DSI) and collaborations with institutions like the PROOF Centre. Alumni of her group hold positions in academia (e.g., George Mason University) and industry (e.g., Merck, BC Cancer Research Centre).

• Statistical Methodology
• High-Dimensional Data Analysis
• Robust Statistics
• +6 more