Find Academic Supervisors

Tracey GlosterView profile

Researcher

• Structural Biology
• Enzymology
• CRISPR Mechanisms
• +3 more

Dr. Tracey Gloster is a researcher in the School of Biology at the University of St Andrews, focusing on the structure and function of carbohydrate processing enzymes and CRISPR-Cas systems. Her work contributes to understanding biological roles of carbohydrates in cellular processes and their malfunction in diseases like cancer and neurodegenerative disorders. She leads projects such as 'Expanding the structural biology toolkit' funded by The Royal Society and has been a PI on Wellcome Trust grants. Research Interests: Carbohydrate processing enzymes (e.g., heparan sulfate degradation) CRISPR-Cas systems and anti-CRISPR proteins Cyclic nucleotide signaling and protein activation mechanisms Structural biology and enzymology Recent Publications Trends: Her articles emphasize CRISPR defense mechanisms, cyclic nucleotide regulation of nucleases, and bioinformatic tools for CAZyme analysis. Key topics include anti-CRISPR proteins, enzyme inhibition strategies, and structural insights into CRISPR effectors. Awards: 2012 Biochemical Society Early Career Research Award 2016 Election to Young Academy of Scotland 2013 L'Oreal-UNESCO For Women In Science Fellowship Grants & Activities: She has secured funding for structural biology projects and collaborates on advanced mass spectrometry tools. Active in organizing workshops (e.g., Scottish Structural Biology) and hosting academic visitors. Served as an external PhD examiner at the University of York. Labs/Teams: Engaged in interdisciplinary research within the Institute of Engineering Biomedical Sciences Research Complex, focusing on structural biology and enzymology applications.

Brian HedlundView profile

Professor

• Microbial Ecology
• Genomics
• Astrobiology
• +3 more

Brian Hedlund is a Professor in the Department of Life Sciences at the University of Nevada, Las Vegas (UNLV). His research focuses on microbial ecology and genomics, particularly in extremophilic environments such as geothermal springs. He leads studies exploring microbial biodiversity, including 'dark' lineages of bacteria that remain underexplored. Hedlund employs advanced techniques like single-cell genomics, metagenomics, and stable isotope analysis to understand microbial roles in ecological processes. His work bridges fundamental research with applied biotechnology, including biofuels development and disease diagnostics. Hedlund’s research is funded by major agencies like NSF, NASA, DOE, and NIH. He co-authored the SeqCode, a nomenclatural system for naming uncultivated prokaryotes based on genomic data, and serves on grant review panels for national funding bodies. Education: Ph.D., Microbiology, University of Washington B.S., Biology, University of Illinois Research Interests: Microbial biodiversity in extreme environments Functional genomics of uncultivated microorganisms Applications in astrobiology and biotechnology International collaborations, particularly with China Grants & Funding: Major support from NSF, NASA, DOE, and NIH SeqCode development and microbial naming initiatives Labs & Teams: Hedlund collaborates with industrial and academic partners on projects ranging from biofuels to human microbiome studies, emphasizing interdisciplinary approaches.

• Membrane Protein Biology
• Protein Synthesis
• Structural Biology
• +6 more

William M. (Bil) Clemons, Jr. is the Arthur and Marian Hanisch Memorial Professor of Biochemistry at the California Institute of Technology (Caltech), affiliated with the Division of Chemistry and Chemical Engineering. He has held this position since 2007, following roles as Assistant Professor of Chemistry at Caltech (2005-2007) and earlier academic appointments. His research focuses on membrane protein structure, protein synthesis and translocation, and structural biology techniques such as X-ray crystallography. Education: B.S. from Virginia Polytechnic Institute and State University (1995), Ph.D. from the University of Utah (2000). Research Interests: The Clemons Lab investigates molecular mechanisms of protein transport across membranes, post-translational modifications like glycosylation, and challenges in membrane protein overexpression. Current projects include the Sec/Tat membrane translocation pathways, eukaryotic glycosylation processes, and the Get3 chaperone system for tail-anchored proteins. Techniques employed include X-ray crystallography, biochemistry, mass spectrometry, and electron microscopy. Publications reflect a blend of experimental structural biology and discussions on equity in science, including studies on phage antibiotics, DPAGT1 inhibitors, and the experiences of Black scientists in biophysics. His work bridges fundamental biological mechanisms with translational applications in drug design. Teaching and Mentorship: Prof. Clemons instructs courses like Ch/Bi 110 (Biochemistry) and contributes to advanced seminars (BMB/Ch 202, BMB/Bi/Ch 173). His lab emphasizes training diverse early-career scientists in structural biology, believing inclusivity drives scientific innovation.

Hilary Ann CollerView profile

Professor

• Cellular Quiescence
• Cancer Biology
• Metabolism
• +4 more

Hilary Ann Coller is a Professor at the University of California, Los Angeles (UCLA), jointly appointed in the Department of Molecular, Cell and Developmental Biology and the Department of Biological Chemistry within the College of Letters and Science. She leads a research laboratory focusing on cellular quiescence, metabolism, and their implications in cancer and disease progression. Her research integrates molecular biology, epigenetics, and systems approaches to study: Transcriptional and epigenetic control of quiescence Metabolic adaptations in tumor microenvironments RNA biology and gene regulation networks Development of biomedical technologies (e.g., biosensors) Recent publications (2022–2025) highlight trends in: Cellular quiescence mechanisms and transcription factor dynamics Cancer epigenetics and metabolic reprogramming Innovative tools for metabolomics and drug monitoring Educational research on remote STEM training programs She directs multiple NIH-funded projects, including R01CA221296 (stromal autophagy in melanoma) and R01GM086465 (microRNA mechanisms). Her lab mentors graduate students and postdocs, and she co-leads UCLA’s Bruins-in-Genomics summer initiative for undergraduate computational biology training.

Marc RousselView profile

Professor

• Biochemical Systems Analysis
• Mathematical Biology
• Chemical Kinetics
• +3 more

Marc Roussel is a Professor in the Department of Chemistry and Biochemistry at the University of Lethbridge, affiliated with the Alberta RNA Research and Training Institute. His research focuses on mathematical modeling of biochemical systems, enzyme kinetics, and systems biology. He has authored multiple books, including Foundations of Chemical Kinetics and A Life Scientist's Guide to Physical Chemistry . His work bridges mathematics and biology, emphasizing dynamical systems, delay differential equations, and model reduction techniques. He has received the 2024 Distinguished Teaching Award from the University of Lethbridge. Key research areas include biochemical networks, gene expression dynamics, and metabolic modeling. Roussel collaborates with experimentalists to study complex biological phenomena such as circadian rhythms, somite formation, and enzyme mechanisms. His contributions span theoretical frameworks, computational methods, and interdisciplinary applications in systems biology.

Michael SuitsView profile

Associate Professor

• Structural Biology
• Carbohydrate Recognition
• X-ray Crystallography
• +2 more

Michael Suits is an Associate Professor in the Department of Chemistry and Biochemistry at Wilfrid Laurier University. His research focuses on structural biology approaches to understanding carbohydrate recognition and processing in bacterial systems, particularly in oral microbiomes and biofilm formations. His research examines: Structural mechanisms of carbohydrate-active enzymes Microbial glycobiology in human pathogens X-ray crystallography of protein-carbohydrate complexes Bacterial polysaccharide degradation pathways Metabolic adaptations in gut and oral microbiota Analysis of his publication history shows consistent focus on enzyme mechanisms in carbohydrate metabolism across various bacterial systems, with recent emphasis on structural characterization of glycoside hydrolases and polysaccharide utilization in human microbiome pathogens. Dr. Suits maintains active research collaborations and directs laboratory investigations into microbial carbohydrate processing mechanisms at the atomic level.

• Neurobiology
• Neuroscience
• Cortical Plasticity
• +4 more

Joshua Trachtenberg is a Professor in the Department of Neurobiology at the School of Medicine, University of California Los Angeles (UCLA) . His research focuses on understanding how early sensory experiences shape synaptic and network connectivity in cortical circuits, particularly in the visual system. Key Research Areas: Mechanisms of experience-dependent cortical plasticity Role of vision in neural circuit development Molecular pathways in autism-related models Inhibitory interneuron dynamics Long-term in vivo imaging of dendritic spines Recent Publications highlight studies on dendritic spine clustering, critical period plasticity, and retinal cell type evolution, with methodologies spanning multi-photon imaging and single-cell transcriptomics. Funding Highlights: NIH R01EY027407 (Disinhibition & Visual Plasticity) NIH R01EY023871 (Inhibitory Circuit Regulation) NIH R01MH082935 (PTEN-Associated Autism Models) Labs & Collaborations include work with the Silva, Golshani, and Geschwind groups, focusing on synaptic stability, cortical dysfunction, and autism-related protein studies.

• Polymer Chemistry
• Self-Assembly
• Drug Delivery
• +3 more

Paul Joshua Hurst is a Postdoctoral Scholar in the Department of Chemistry at Stanford University, affiliated with the School of Humanities and Sciences. His research focuses on advanced polymer chemistry, self-assembly mechanisms, and their biomedical applications. He explores topics such as drug delivery systems, nanomedicines, and cryo-electron microscopy for material characterization. His work integrates interdisciplinary approaches, combining organic synthesis, materials science, and biophysics. Key areas of investigation include the design of bioreducible polymers for mRNA delivery, chemically driven hydrogel systems, and the structural analysis of enzyme@metal-organic frameworks using cryo-EM. He is affiliated with the CMAD, ChEM-H, and SSRL research programs. Recent research trends show a focus on reaction-driven self-assembly, sustainable polymer synthesis, and dynamic materials with tunable properties. His studies emphasize both fundamental mechanisms and translational applications in drug delivery and nanotechnology. No scientific awards have been listed in the provided information. While no student advisees are mentioned, his research contributions span over 15 peer-reviewed articles from 2020 to 2025, reflecting a strong publication trajectory in top-tier journals. His work is supported through collaborations with Stanford’s affiliated programs.

Jana SeifertView profile

Professor

• Microbiology
• Animal Science
• Environmental Microbiology
• +4 more

Prof. Dr. Jana Seifert is a full professor in the Department of Functional Microbiology in Farm Animals at the University of Hohenheim, Germany. She leads the Functional Microbiology research group and serves as the Equal Opportunities Officer for the Faculty of Agricultural Sciences. Her work focuses on microbiome-animal interactions, particularly in livestock, and the functional roles of gut microbiota in nutrient utilization and metabolic processes. Education: Jana Seifert holds a PhD in Biology from the Technical University Bergakademie Freiberg, Germany, and completed postdoctoral research in geomicrobiology at the Helmholtz Center for Environmental Research (UFZ), Leipzig. She transitioned to agricultural microbiology as a junior professor (2013–2018) before assuming her current full professorship in 2019. Research interests include microbial community functionality, metaproteomics, and the application of molecular techniques to study microbial contributions to methane reduction in dairy cows, protein utilization in pigs, and host-microbiome interactions. Key projects include Methabreed (reducing methane emissions via breeding strategies) and WiMiQ (host-microbiome energy metabolism in dairy cows). Her recent publications emphasize metaproteomics, microbiome-driven biomarkers, and the impact of dietary interventions on microbial ecology. Collaborations span institutions like the Hebrew University of Jerusalem and the Friedrich-Loeffler-Institut (FLI), Braunschweig.

Sheheeda Mariam ManakkaduView profile

Associate Professor

• Robotics
• Data Analytics
• Machine Learning
• +4 more

Sheheeda Mariam Manakkadu is an Associate Professor in the Department of Computer Science at Southern Illinois University Carbondale. She teaches graduate courses in Data Structures, Object-Oriented Programming, Data Mining, Text Mining, and Cloud Architecture, along with undergraduate courses in Operating Systems and Data Analytics. Ph.D., Computer Engineering M.E., Biomedical Engineering Her research spans robotics, data analytics, and parallel computing. Key areas include adaptive control of robotic manipulators, big data processing via MapReduce, IoT resource allocation, and computational bioinformatics for protein networks. Recent publications focus on neuro-sliding mode control, cloud architecture, and scalable recommender systems. She actively participates in academic service as a committee member for graduate courses and the IEEE Erie Section. Her work integrates machine learning, optimization algorithms, and distributed systems across diverse domains.

Irene NobeliView profile

Senior Lecturer

• Bioinformatics
• Transcriptomics
• Regulatory RNAs
• +3 more

Dr. Irene Nobeli is a Senior Lecturer and Education Lead (PG taught courses) at the School of Natural Sciences, Birkbeck, University of London. She specializes in computational biology and chemoinformatics, focusing on regulatory RNAs, transcriptomics in health/disease, brain disorders, and small molecule roles in biology. Her work bridges bioinformatics tools development and translational research. Administrative roles include directing the MSc Bioinformatics program and organizing the Sequence Analysis and Omics module. She collaborates with research centers like the Birkbeck Institute for Data Analytics (BIDA) and the Institute of Structural Molecular Biology (ISMB). Research interests span bioinformatics methodologies, Mycobacterium genomics, neurodevelopmental disorders, and computational drug design. Notable contributions include developing flexiMAP (alternative polyadenylation analysis) and baerhunter (bacterial non-coding RNA detection). Publications highlight her expertise in transcriptomics, bacterial pathogenesis, and neurobiological mechanisms. She actively engages in advancing computational methods for genomic data interpretation and translational medicine.

• Neuropathology
• Neurodegenerative diseases
• Alzheimer's Disease
• +3 more

Charles L. White is Professor of Pathology at UT Southwestern Medical Center, where he holds the Nancy R. McCune Distinguished Chair in Alzheimer Disease Research. He has served as Director of Neuropathology at UT Southwestern since completing his residency and fellowship training in anatomic pathology and neuropathology at Johns Hopkins in 1983. Dr. White also directs the Neuropathology Core of the UT Southwestern Alzheimer Disease Research Center (established 1988) and the Winspear Family Special Center for Research on the Neuropathology of Alzheimer's Disease (established 2002). Dr. White completed his medical and pathology training at Johns Hopkins University, establishing a career focused on neurodegenerative brain disorders. His educational background forms the foundation for his dual expertise in clinical neuropathology and research investigation. Dr. White's research spans multiple critical areas of neuropathology: Pathological mechanisms of Alzheimer's disease and related dementias Tau protein aggregation and propagation across neurodegenerative conditions Diagnostic criteria and staging systems for various neuropathologies Genetic and molecular underpinnings of frontotemporal lobar degeneration Chronic traumatic encephalopathy and its relationship to other neurodegenerative conditions Development of artificial intelligence approaches for neuropathological assessment Analysis of Dr. White's extensive publication record reveals a consistent focus on defining and characterizing neurodegenerative disease processes through rigorous pathological examination. His work frequently addresses diagnostic criteria, disease classification systems, and the molecular mechanisms underlying various neurodegenerative conditions. There is particular emphasis on tau pathology across multiple disease states, including Alzheimer's disease, primary age-related tauopathy (PART), and chronic traumatic encephalopathy (CTE). His research often involves large collaborative efforts with multiple institutions, reflecting the complex, multidisciplinary nature of modern neuropathological research. Dr. White has received significant recognition for his contributions to the field: Award for Meritorious Contributions to Neuropathology from the American Association of Neuropathologists (2020) Nancy R. McCune Distinguished Chair in Alzheimer Disease Research As an educator and mentor, Dr. White serves as Training Director for the Neuropathology Fellowship program at UT Southwestern, an ACGME-accredited, 2-year training program. Twenty-two trainees have completed the program and become board certified by the American Board of Pathology in the subspecialty of Neuropathology. He has held significant leadership positions including past president of the American Association of Neuropathologists, the national professional organization for neuropathologists in the US. His mentorship extends to numerous research collaborations where he guides junior investigators in neuropathological research methods and interpretation. Dr. White directs multiple research centers including the Neuropathology Core of the UT Southwestern Alzheimer Disease Research Center and the Winspear Family Special Center for Research on the Neuropathology of Alzheimer's Disease. His laboratory work focuses on understanding the pathological mechanisms of neurodegenerative diseases, particularly those involving protein misfolding and aggregation. His team employs advanced techniques including immunohistochemistry, molecular pathology, and increasingly, artificial intelligence approaches to analyze neuropathological specimens.

Carmen BirchmeierView profile

Professor

• Developmental Biology
• Cell Biology
• Neuroscience
• +3 more

Carmen Birchmeier is a Full Professor at the Medical Faculty of Charité - Universitätsmedizin Berlin and a leading researcher at the Max Delbrück Center for Molecular Medicine (MDC). She coordinates the MDC Neuroscience Program and serves on the Executive Board of the NeuroCure Cluster of Excellence. Her research focuses on developmental biology, cell signaling, and the molecular mechanisms underlying nervous system and muscle development. Education: PhD in Molecular Biology from the University of Zürich (1984), followed by postdoctoral training at Cold Spring Harbor Laboratory (1984–1989). She established her independent research group at the Max Delbrück Lab in Cologne (1989–1995) before moving to Berlin. Research Interests: Investigates signal transduction pathways (e.g., Notch, ErbB, and c-Met) in developmental processes, including neural crest cell migration, muscle progenitor cell differentiation, and Schwann cell myelination. Her work bridges molecular genetics, mouse models, and cellular biology to uncover mechanisms of tissue formation and disease. Awards: Recipient of the Leibniz Award (2002) and EMBO Membership (2001). Her contributions to developmental neurobiology have been recognized internationally. Leadership & Grants: Deputy Speaker of SFB 665 (Developmental Disturbances of the Brain), DFG Fachkollegium Member, and advisor to multiple institutes including the Max Planck Institute for Biophysical Chemistry. Her work spans academic and clinical research collaborations. Labs/Teams: Heads the Signal Transduction/Developmental Biology Research Group at MDC, focusing on interdisciplinary approaches to understand developmental disorders and regenerative medicine strategies.

John DiffleyView profile

Professor

• DNA replication
• Cell cycle control
• Genome stability

John Diffley is a distinguished molecular biologist specializing in DNA replication and cell cycle control. He serves as Director of Clare Hall Laboratories and Deputy Director of the London Research Institute since 2006. Additionally, he holds the position of Honorary Full Professor in the Department of Biology at University College London since 1999. His research has significantly advanced our understanding of the mechanisms controlling DNA replication in eukaryotic cells. Professor Diffley's research focuses on three primary areas: DNA replication, cell cycle control, and genome stability. His work has elucidated key mechanisms in replication initiation, origin licensing, and the coordination between DNA replication and cell cycle progression. His laboratory has made seminal contributions to understanding how replication proteins assemble at origins of replication and how this process is regulated throughout the cell cycle. Analysis of Professor Diffley's recent publications reveals a strong focus on the molecular mechanisms of DNA replication initiation and control. His work spans from structural studies of replication complexes to systems-level analyses of replication timing and its relationship to gene expression. A recurring theme is the investigation of how DNA damage checkpoints regulate replication processes to maintain genome stability. His research employs diverse model systems including budding yeast and human cells, demonstrating the evolutionary conservation of core replication mechanisms. Elected member of European Molecular Biology Organisation (EMBO) (1998) Paul Marks Prize for Cancer Research (2003) Elected Fellow of the Royal Society (2005) Member of Academia Europaea (2009) Member of the European Academy of Cancer Sciences (2011) Fellow of the Academy of Medical Sciences (2011) Throughout his career, Professor Diffley has led the Chromosome Replication Laboratory, first at ICRF Clare Hall Laboratories (1990-1999) and subsequently at the London Research Institute. His laboratory has received substantial funding from Cancer Research UK and other major research organizations to investigate the fundamental mechanisms of DNA replication. Professor Diffley has mentored numerous graduate students and postdoctoral researchers who have gone on to establish independent research careers in molecular biology and related fields. Professor Diffley's research group, the Chromosome Replication Laboratory, operates at the forefront of DNA replication research. The laboratory combines biochemical, genetic, and cell biological approaches to dissect the complex machinery that ensures accurate DNA replication. Their work has important implications for understanding cancer development, as defects in DNA replication control are a hallmark of cancer cells.

Yuhang HuView profile

Associate Professor

• Mechanics of Soft Materials
• Materials Chemistry
• Biomedical Engineering
• +7 more

Dr. Yuhang Hu is an Associate Professor at the Georgia Institute of Technology, affiliated with the George W. Woodruff School of Mechanical Engineering and the School of Chemical and Biomolecular Engineering. Her research focuses on soft active materials, particularly hybrid systems combining solid and liquid components. She explores chemo-mechanical modeling, mechanical characterization of soft materials, and the development of dynamic multi-functional materials for applications like energy conversion and biomedical devices. Education: Ph.D. in Engineering Sciences from Harvard University (2011), M.S. in Applied Physics (Harvard, 2009), and prior degrees from Nanyang Technological University and Shanghai Jiao Tong University. She previously held positions at the University of Illinois at Urbana-Champaign and Harvard. Research Interests: Soft materials mechanics, stimuli-responsive gels, bio-inspired materials, and material characterization challenges. Her work integrates experimental and theoretical approaches to bridge mechanics and materials chemistry. Outreach: Active in STEM education through initiatives like B.T. Washington Elementary STEM Academy and the Midwest Experimental Mechanics Student Conference. Her lab emphasizes interdisciplinary innovation at the Chemomechanics of Soft Materials Lab.