Dr. Annemieke Apergis-Schoute is a Lecturer in Psychology (Teaching and Research) at Queen Mary University of London, affiliated with the School of Biological and Behavioural Sciences and the Centre for Brain and Behaviour. Her research focuses on obsessive-compulsive disorder (OCD), cognitive flexibility, prefrontal mechanisms, and student mental health. She holds a PhD from New York University, where her early work explored threat learning in rats and humans using fMRI. Subsequent roles at the University of Cambridge and UCL expanded her expertise into clinical OCD studies, including deep brain stimulation trials. Her research investigates how prefrontal control deficits and inflexible learning contribute to OCD and related disorders, with a focus on adolescents and young adults. Collaborations include pioneering DBS studies targeting basal ganglia regions to reduce compulsive behaviors. She also explores connections between brain function, interoception, and mental health in daily decision-making contexts. Key publications analyze reversal learning deficits in OCD under serotonergic modulation, neuroimaging markers of cognitive rigidity, and developmental trajectories of compulsivity. Her work bridges basic neuroscience with translational clinical interventions, emphasizing early intervention strategies and cognitive-behavioral approaches.
