Mark S. WorkentinView profile
Professor
Mark S. Workentin is a Professor in the Department of Chemistry within the Faculty of Science at Western University. His research focuses on physical organic chemistry of materials, specializing in noble metal nanoclusters and their surface functionalization for biomedical and technological applications. Education: Ph.D., McMaster University, 1992 B.Sc., Western Ontario, 1988 Workentin's research investigates the structure-reactivity relationships of gold and silver nanomaterials, designing ligands for post-synthesis functionalization via bioorthogonal 'click' chemistry. His group pioneers interfacial reactions that enable precise surface modifications under mild conditions, bridging physical organic chemistry with materials science to create platforms for nano-medicines, bio-imaging, and molecular electronics. The work emphasizes controlled nanocluster synthesis through regioisomeric ligand modifications and explores photo/electrochemical surface reactivity. Analysis of his 2019-2025 publications reveals a consistent trajectory toward functional nanomaterial design, with increasing emphasis on biological applications (protocell models, drug delivery) while maintaining core expertise in surface chemistry and click reactions. The research demonstrates strong interdisciplinary collaboration across chemistry, materials science, and biomedical engineering. Scientific Awards: Edward G. Pleva Award for Excellence in Teaching University Faculty Scholar Fellow, Canadian Institute for Chemistry Premier's Research Excellence Award Western Marilyn Robinson Award for Excellence in Teaching Alumni Western Teaching Award (three cycles) CNC-IUPAC Award OCUFA Award for Excellence in University Teaching Workentin has trained over 18 years of highly qualified personnel (HQP) with 100% professional placement success. His group masters organic synthesis, materials characterization, electrochemistry, and photochemistry techniques while developing transferable skills for industrial innovation. Major funding includes the Premier's Research Excellence Award supporting nanocluster technology development. The @WorkentinChem group operates from labs in the Chemistry Building (Room 203), collaborating with academic and industrial partners to translate fundamental surface chemistry discoveries into applications for nano-medicines, sensors, and catalytic systems through their 'interchangeable toolbox' approach to interfacial reactions.







