Find Academic Supervisors

• Kidney Disease
• Nephrology
• Immunology
• +5 more

Associate Professor Guoping Zheng is affiliated with the Westmead Clinical School at the University of Sydney, specializing in nephrology and immunology. His research focuses on kidney fibrosis, inflammation, and the roles of macrophages, TGF-β signaling, and β-catenin in renal pathologies. He collaborates with institutions like the Norris Comprehensive Cancer Research Center (University of Southern California) on Wnt/b-catenin inhibitor studies. Key research interests include the molecular mechanisms of kidney disease progression, particularly in chronic conditions and transplant fibrosis. He has secured grants from the National Health and Medical Research Council (NHMRC), including a Peter Doherty Fellowship (2006) and recent grants targeting β-catenin/FoxO pathways and kidney failure prevention. His work spans experimental models of kidney injury and translational therapies. Publications highlight contributions to understanding renal fibrosis, macrophage biology, and TGF-β's dual roles in inflammation/fibrosis. Recent studies investigate therapeutic strategies like Flt3 inhibitors and engineered macrophages. His team actively supervises research projects on MMPs, E-cadherin, and β-catenin in kidney disease pathogenesis. Grants : Over 10 NHMRC grants since 2006, including $2.5M+ for fibrosis research. Students : Advises Xutong HU on AKI-to-CKD transition mechanisms. Labs/Teams : Collaborates with multidisciplinary groups in nephrology and immunology.

Gerhard SchrattView profile

Professor

• Molecular Neuroscience
• Synaptic Plasticity
• Non-coding RNAs
• +1 more

Gerhard Schratt is Full Professor and Head of the Institute for Neuroscience at ETH Zürich. His laboratory investigates molecular mechanisms of synapse development and plasticity, with emphasis on non-coding RNA regulation in neurological disorders. Research integrates molecular neurobiology with computational approaches to study microRNA functions in neuronal development, synaptic homeostasis, and stress responses. Current projects examine RNA-based therapies for neurodegenerative conditions and computational pathology platforms for digital histology. Professor Schratt's group develops AI frameworks for neurological assessment including multimodal dementia diagnosis, voice-based cognitive testing with privacy protection, and digital pathology for kidney disease. Collaborative projects with the Chan Zuckerberg Initiative explore mitochondrial regulation by microRNAs. He teaches molecular neurophysiology and neuroscience courses, supervising doctoral candidates in systems neuroscience approaches.

• Kidney Diseases
• Pathology
• Podocyte Function
• +4 more

David Cimbaluk is an Associate Professor in the Department of Pathology at Rush University's Rush Medical College, Chicago. His research focuses on kidney diseases, immunology, and molecular pathology, with a strong emphasis on podocyte function, inflammation pathways, and diagnostic methods for renal disorders. He has collaborated extensively on studies involving kidney disease mechanisms, autoimmune conditions like systemic lupus erythematosus, and novel therapeutic strategies for cancer and transplantation. His work spans experimental models (e.g., mouse studies) and clinical applications, including the development of diagnostic techniques like fine-needle aspiration and spatialomic profiling. Key areas include CD11b receptor modulation, miRNA regulation in diabetic nephropathy, and the role of SuPAR in viral-induced proteinuria. He has also contributed to understanding genetic syndromes like Alport Syndrome and X-linked conditions. Education: Not explicitly stated in text, inferred to include advanced training in pathology and molecular biology. Publications: Over 30 peer-reviewed articles since 2005, focusing on nephrology, immunology, and diagnostic pathology. His publications highlight interdisciplinary collaboration, with frequent co-authorship in journals like Nature Communications , JCI Insight , and Journal of Clinical Investigation . Research trends emphasize translational studies linking molecular mechanisms to clinical outcomes in renal and autoimmune diseases. Notable contributions include defining SuPAR's role in kidney disease, developing the SeqStain spatial profiling method, and investigating miR-146a's role in diabetic glomerulopathy. Collaborations with institutions like the University of Chicago and international teams underscore his global impact.

• Cellular Biology
• Stem Cell Research
• Developmental Biology
• +3 more

Bo Sun is a Research Fellow in the Department of Anatomy & Developmental Biology at Monash University. Their research focuses on cellular reprogramming, stem cell biology, and disease modeling, particularly in contexts like SARS-CoV-2 pathogenesis, Alzheimer’s disease, and kidney disorders. Sun collaborates extensively with global teams and contributes to UN Sustainable Development Goals through health-related research. Active Project: Scalable lentiviral screening of variants associated with kidney disease (2025–2026) Key Collaborators: Polo J.M., Subbarao K., Mackay C.R., and others Research Interests emphasize: - Stem cell models of organ systems (lung, heart, placenta) - Mechanisms of cellular plasticity and reprogramming - Molecular pathways in fibrosis and metabolic disease Publications span interdisciplinary topics, with 2023 studies highlighting SARS-CoV-2 placental infection and Alzheimer’s disease mitigation via microbiota metabolites. Earlier work includes renal fibrosis mechanisms and podocyte dysfunction. Sun’s work is frequently cited and has been featured in news outlets and social platforms. Grant involvement includes a Chief Investigator role in kidney disease research funded from 2025–2026. Advising and mentorship details are not explicitly listed in the provided data. Labs/Teams: Collaborates within Monash’s developmental and regenerative medicine research groups, focusing on pluripotency and disease modeling.

Fabian BraunView profile

Researcher

• Nephrology
• Kidney Diseases
• Fabry Disease
• +7 more

Fabian Braun is a medical researcher at the University Medical Center Hamburg-Eppendorf, affiliated with the Department of Medicine. His work focuses on kidney diseases, particularly Fabry disease and podocyte biology, with extensive publications in nephrology journals. He has made significant contributions to understanding renal pathology mechanisms and biomarker discovery. III. Department of Medicine, University Medical Center Hamburg-Eppendorf Active researcher with numerous publications from 2013-2025 ORCID: 0000-0002-4742-050X Dr. Braun's research primarily centers on molecular mechanisms underlying renal pathology in Fabry's disease, microvesicular signaling in renal health and disease, and the discovery of novel urinary microvesicular biomarkers. His work bridges basic science with clinical applications, particularly in understanding podocyte injury mechanisms and kidney disease progression. Analysis of his recent publications reveals a strong focus on kidney disease mechanisms, particularly Fabry nephropathy, podocyte biology, and extracellular vesicle research. His work has expanded to include studies on SARS-CoV-2 renal tropism and multi-organ involvement during the pandemic, demonstrating adaptability to emerging health challenges while maintaining focus on kidney pathophysiology. Dr. Braun has been involved in significant collaborative efforts, including the MISEV2023 guidelines for extracellular vesicle studies and the German Porphyria Registry. His research has appeared in high-impact journals including Nature Communications, Journal of Clinical Investigation, and Kidney International. As an active researcher, Dr. Braun has contributed to numerous collaborative projects and has been involved in advancing methodologies for kidney tissue analysis and biomarker discovery. His work with kidney organoids and multi-omics approaches represents cutting-edge research in nephrology. Dr. Braun is part of research teams focusing on kidney disease mechanisms, particularly within the Department of Medicine at University Medical Center Hamburg-Eppendorf, collaborating with international researchers on projects related to podocyte biology and kidney disease pathogenesis.

Nicole Maria MuscholView profile

Professor

• Rare Genetic Disorders
• Lysosomal Storage Diseases
• Metabolic Disorders
• +7 more

Nicole Maria Muschol is a Professor in the Department of Pediatrics at the University Medical Center Hamburg-Eppendorf. Her research focuses on rare genetic disorders, particularly lysosomal storage diseases including Fabry disease, mucopolysaccharidoses (MPS), mucolipidoses, Pompe disease, and alpha-mannosidosis. She is actively involved in clinical research examining enzyme replacement therapies and other treatment modalities for these rare conditions. Dr. Muschol's research interests encompass the clinical manifestations, disease progression, and therapeutic interventions for various rare metabolic disorders. Her work particularly emphasizes gender-specific differences in Fabry disease, neurological manifestations in mucolipidoses, and the long-term outcomes of enzyme replacement therapy across multiple rare diseases. She investigates both the clinical phenotypes and underlying molecular mechanisms of these disorders through translational research approaches that bridge basic science and clinical applications. Her publication record demonstrates a strong focus on treatment outcomes, with numerous studies examining enzyme replacement therapy efficacy across different lysosomal storage disorders. Recent publications have particularly emphasized Fabry disease in females, alpha-mannosidosis management, and neurocognitive aspects of mucolipidosis. Her work often involves large-scale multicenter studies and global collaborations to address the challenges of researching ultra-rare diseases. Dr. Muschol has contributed to developing consensus guidelines for clinical care of Sanfilippo syndrome and has participated in numerous clinical trials for rare disease treatments. Her research spans from basic investigations of disease mechanisms to clinical outcome studies and quality-of-life assessments for patients with these rare conditions.

• Autoimmune Diseases
• Nephrology
• Podocyte Biology
• +2 more

Dr. S. Frömbling is a researcher affiliated with DESY (Deutsches Elektronen-Synchrotron) specializing in medical research, particularly in autoimmune kidney diseases and podocyte biology. Their work focuses on the mechanistic significance of the ubiquitin proteasome system in autoimmune environments affecting kidney function. Research interests include podocyte injury mechanisms , ubiquitin C-terminal hydrolase L1 function , and autoimmune glomerulonephritis . Their research examines how non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in membranous nephropathy, where autoantibodies target podocytes of the glomerular filter resulting in proteinuria. Dr. Frömbling has published in high-impact journals, with their most notable work appearing in Nature Communications (2023), which investigated the relationship between proteasome impairment and autoimmune kidney disease. This research represents important contributions to understanding the molecular mechanisms underlying autoimmune kidney disorders.

• Autoimmune diseases
• Kidney diseases
• Molecular biology
• +3 more

I. Hermans-Borgmeyer is a researcher actively contributing to the field of molecular mechanisms in kidney autoimmune diseases, with recent publications in high-impact journals. Their work focuses on the role of the ubiquitin proteasome system in autoimmune glomerulonephritis, particularly examining how non-functional ubiquitin C-terminal hydrolase L1 affects podocyte injury. Research interests span autoimmune diseases, kidney pathophysiology, molecular biology of proteasome function, and podocyte biology. Their work provides critical insights into the mechanisms of membranous nephropathy where autoantibodies target podocytes of the glomerular filter resulting in proteinuria. Recent publications demonstrate expertise in examining how impairment of the ubiquitin proteasome system contributes to kidney autoimmune pathology. The research combines molecular biology techniques with disease modeling to elucidate pathways involved in podocyte injury. The work represents significant contributions to understanding the pathogenesis of autoimmune kidney diseases and potential therapeutic targets related to proteasome function.

Hans PinnschmidtView profile

Researcher

• Medical Biometry
• Epidemiology
• Clinical Research
• +6 more

Hans Pinnschmidt is a researcher at the Department of Medical Biometry and Epidemiology , Universitätsklinikum Hamburg-Eppendorf. His work spans clinical research, neuroscience, and surgical outcomes, with a focus on data-driven medical analysis. Key Research Areas: Medical Biometry (statistical analysis in clinical settings) Epidemiology of infectious diseases and stroke Neurological complications in critical care Anesthesia and surgical outcome optimization Recent Article Trends: 2025 critique on gentamicin's role in listeriosis mortality 2024 neurology studies on ECMO patients and glioma subtypes 2023 anesthesia research for Parkinsonian and liver surgery patients 2022 VR medical education during pandemic

• Circadian Rhythm
• Macrophage Biology
• NF-κB Signaling
• +5 more

Dr. James Bagnall is a Research Fellow at the University of Manchester's Faculty of Biology, Medicine and Health, specifically within the Division of Neuroscience and Experimental Psychology. His research spans molecular biology, immunology, and chronobiology, focusing on the intersection of circadian rhythms and cellular signaling pathways. With a robust publication record extending to 2025, he maintains an active research program investigating how biological clocks regulate cellular functions in both healthy and disease states. ORCID: 0000-0003-1735-5855 Primary research institution: University of Manchester Research focus areas: Circadian biology, macrophage function, NF-κB signaling Dr. Bagnall's research interests center on understanding how circadian rhythms regulate fundamental cellular processes. His work demonstrates that biological clocks exert precise temporal control over gene expression, protein dynamics, and cellular responses to environmental stimuli. He has made significant contributions to understanding how the circadian system regulates macrophage function, inflammatory responses, and kidney physiology. His approach integrates quantitative live-cell imaging, mathematical modeling, and molecular biology to reveal the mechanisms underlying circadian control of cellular processes. Analysis of Dr. Bagnall's publication record reveals a clear trajectory of research focused on quantitative approaches to understanding circadian regulation. His work consistently applies advanced imaging techniques to study protein dynamics in living cells, particularly focusing on the suprachiasmatic nucleus (the master circadian clock) and immune cells. A notable theme is how circadian mechanisms interact with inflammatory pathways, particularly the NF-κB signaling system. More recent publications demonstrate expanding applications of his expertise to renal physiology and pulmonary function. Dr. Bagnall has contributed to research that has been recognized through citations and social media engagement, with several papers receiving attention from news outlets and academic sharing platforms. His dataset on hypoxia-inducible factors was notably picked up by 4 news outlets and shared across multiple social media platforms. His research methodology emphasizes quantitative approaches to cell signaling, with particular expertise in live-cell imaging of dynamic processes. Dr. Bagnall frequently collaborates with interdisciplinary teams that combine expertise in molecular biology, mathematics, and clinical medicine, reflecting the translational nature of his work on circadian biology and its implications for human health.

Robert MalletView profile

Professor

• Cardioprotection
• Neuroprotection
• Intermittent Hypoxia
• +3 more

Dr. Robert Mallet is a Professor in the College of Biomedical and Translational Sciences at the University of North Texas Health Science Center, specializing in Physiology & Anatomy. His research focuses on hypoxia-induced organ protection mechanisms, particularly in cardiac and brain tissues under ischemic conditions. He holds a BS in Biology from the Catholic University of America and a PhD in Physiology from George Washington University. Research Interests: Dr. Mallet’s lab investigates how intermittent hypoxia exposure enhances organ resilience to ischemic events like heart attacks and strokes. Key areas include molecular adaptations (e.g., glyoxalase systems, antioxidant responses) and translational applications in clinical settings such as cardiac arrest resuscitation. His work bridges cellular biochemistry with clinical interventions, emphasizing non-invasive therapies like hypoxic training. Projects & Grants: Active grants include NIH-funded studies on hypoxia training for cognitive impairment (NIA, NIH) and minority health initiatives (NIMHD). Recent projects explore pyruvate’s role in organ preservation during cardiac arrest and machine-perfused kidney transplants. Labs/Teams: His lab collaborates across disciplines, focusing on translational studies in cardiovascular and neuroprotection. Current efforts target hypoxia’s role in aging-related cognitive decline and kidney injury mitigation.

• Neurodegeneration
• Disease model development
• Parkinson's disease
• +4 more

John Haynes is a Senior Lecturer at Monash University's Faculty of Pharmacy and Pharmaceutical Sciences, leading the Stem Cell Biology group. He is affiliated with the Monash Institute of Pharmaceutical Sciences and contributes to the Medicinal Chemistry and Drug Action division. His research focuses on neurodegenerative diseases, particularly Parkinson's and Alzheimer's, leveraging stem cell models and drug discovery approaches. Haynes teaches courses in renal physiology, pharmacology, neurodegeneration, and diuretic action. Research interests include disease model development, inflammation mechanisms, and translational therapies. Notably, his work explores stem cell-derived models for neurodegenerative disorders and employs molecular dynamics to enhance drug efficacy. He has led or co-led 18 research projects since 2002, funded by organizations like NHMRC and ARC, focusing on topics such as Alport syndrome, microglial progenitors, and dopaminergic neuron maturation. His publications span 2023 to 1988, with recent work emphasizing stem cell differentiation, neuronal maturation, and stress-Alzheimer's interactions. Haynes has engaged in academic activities, including submissions to government committees and media contributions, such as a 2019 feature on functional food validation tools. He actively supervises PhD students in neurodegeneration projects.

Anne MühligView profile

Physician Scientist

• Pediatric Nephrology
• Podocyte Biology
• Glomerular Diseases
• +3 more

Anne Mühlig is a Medical Specialist in Pediatrics and Youth Medicine at the University Medical Center Hamburg-Eppendorf (UKE), affiliated with the University of Hamburg. She is based in the Center for Obstetrics and Pediatrics, Department of Pediatrics, where she focuses on pediatric nephrology and kidney-related disorders in children. Dr. Mühlig's research spans several critical areas in pediatric kidney diseases. Her work on podocyte biology has revealed how these specialized cells become damaged in conditions like Fabry disease and focal segmental glomerulosclerosis. She has made significant contributions to understanding the complement system's role in kidney pathology , demonstrating that podocytes themselves produce and secrete functional complement components. Her research on genetic kidney disorders and precision medicine approaches aims to develop individualized therapies for children with nephrological conditions. Analysis of her publication record shows a strong emphasis on translational research connecting basic science discoveries with clinical applications. Her most recent work includes developing optimized multiomics protocols for kidney tissue analysis (2024), investigating calcium-sensing receptors in proteinuric conditions (2022), and exploring novel therapeutic approaches like levamisole for nephrotic syndrome (2019). Her research frequently employs advanced techniques including molecular biology, immunohistochemistry, and animal models to understand disease mechanisms. Dr. Mühlig is an active member of the scientific community through her memberships in the American Society of Nephrology and the Gesellschaft für pädiatrische Nephrologie. Her work has been consistently published in high-impact journals including Kidney International, Journal of Clinical Investigation, and Frontiers in Immunology. As a clinician-scientist, Dr. Mühlig maintains dual expertise in patient care and research. She is fluent in both German (her native language) and English, enabling international collaboration and presentation at global conferences. Her ongoing research continues to advance our understanding of pediatric kidney diseases and improve treatment options for young patients.

• Nephrology
• Diabetes Research
• Cell Metabolism
• +4 more

Dr. Sergi Clotet-Freixas is an Assistant Professor at McMaster University , affiliated with the Department of Medicine, Division of Nephrology since August 2023. His research bridges nephrology , diabetes , and sex-based biology , focusing on metabolic and epigenetic crosstalk in kidney diseases. His work employs 'omics methods , cell biology , and proteomics to uncover mechanisms of diabetic kidney disease progression and acute kidney injury post-transplant. Recent studies explore sex dimorphism , mitochondrial preservation , and biomarker discovery in transplantation medicine. Key research areas : Biological sex differences in kidney cells, metabolism-epigenetics interactions, diabetic kidney disease, and allograft rejection. Techniques : Proteomics, transcriptomics, ex vivo organ perfusion, and tissue engineering models.

Zhe HanView profile

Professor

• Drosophila
• Human Disease Models
• Cardiovascular Development
• +5 more

Zhe Han is a Professor at the University of Maryland with primary appointment in Medicine and secondary appointment in Physiology . As Director of the Center for Precision Disease Modeling, he develops Drosophila and human cell models to validate genetic variants causing heart, kidney, blood, muscle, and metabolic diseases, advancing precision medicine approaches. PhD in Molecular, Cellular and Developmental Biology, University of Michigan (2002) Postdoc in Molecular Biology, UT Southwestern (2006) His lab pioneered Drosophila as a high-throughput system for congenital heart disease and genetic kidney diseases , discovering nephrocyte-podocyte functional equivalence and developing gene replacement methods. Recent work includes COVID-19 pathogenic protein identification and APOL1 nephropathy mechanisms . Key research areas: Heart development and disease Kidney filtration and reabsorption Genetic variant validation Drug discovery for rare diseases Comparative disease modeling Major scientific contributions include: Establishing Drosophila heart as CHD validation platform First in vivo nephrocyte functional assay Identifying Q10 as COQ2 nephropathy treatment APOL1 nephropathy mechanism discovery SARS-CoV-2 Nsp6 pathogenicity elucidation Scientific leadership includes: Multiple NIH R01 grants (2008-present) NIH INCLUDE Supplement (2019) Community mentorship at Thomas Jefferson High School Leadership in Society of Chinese Bioscientists in America His work bridges Drosophila genetics with human clinical applications, focusing on translational mechanisms and targeted therapies for genetically complex diseases.