Mehmet KoyutürkView profile
Professor
Mehmet Koyutürk serves as the Andrew R. Jennings Professor in the Department of Computer and Data Sciences at Case Western Reserve University's Case School of Engineering, with additional affiliation as a Member of the Cancer Genomics and Epigenomics Program at the Case Comprehensive Cancer Center. His computational research bridges algorithm development with biological applications, focusing on network-structured data analysis to address complex biomedical challenges. Dr. Koyutürk earned his Ph.D. in Computer Science from Purdue University following B.S. and M.S. degrees in Electrical Engineering and Computer Engineering from Bilkent University. His primary research domains include high-throughput biological data analysis, systems/network biology methodologies, data mining algorithms, and scientific computing optimization, with particular emphasis on phosphorylation networks, genomic interactions, and multi-omics integration. Recent publication trends reveal expanding applications of his network science expertise into Alzheimer's disease phosphoproteomics, bipolar disorder biomarker discovery, and intimate partner violence analysis, while maintaining core contributions to graph neural networks and biological link prediction. His group actively develops open-source analytical tools like RokaiXplorer for phospho-proteomic data accessibility. Scientific Recognition Andrew R. Jennings Professorship Dr. Koyutürk leads multiple NIH-funded initiatives including R01-LM012980 for phosphoproteomics analysis, U01-CA198941 (BD2K program) for big network integration, and R01-LM011247 for GWAS enhancement, complemented by NSF CAREER Award CCF-0953195. He serves on the steering committee for CWRU's Systems Biology and Bioinformatics graduate programs and as Associate Editor for IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB), with extensive collaboration through Mark Chance's Center for Proteomics and Bioinformatics. His laboratory specializes in developing scalable algorithms for biological network analysis, currently advancing projects on kinase-substrate association prediction, co-phosphorylation network characterization in cancer, and network-based approaches to intimate partner violence data mining, with strong emphasis on translating computational methods into biomedical insights through open-source software dissemination.








