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Eugene KooninView profile

Adjunct Professor

Graz University of TechnologyAustria

Eugene Koonin is a Senior Investigator at the National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), NIH, and holds adjunct professorships at Georgia Institute of Technology, Boston University, and the University of Haifa. A leading figure in evolutionary biology and computational genomics, he has made foundational contributions to comparative genomics, virus evolution, and the analysis of horizontal gene transfer. Education: BS in Biochemistry, Moscow State University (1978) PhD in Molecular Biology, Moscow State University (1983) Research Interests: His work spans evolutionary genomics, virus-host coevolution, discovery of novel viruses through metagenomics, and the evolutionary regimes of human cancers. He pioneered the Clusters of Orthologous Genes (COG) system and investigates thermodynamic principles underlying evolution. Publications: His recent work includes groundbreaking studies on gut viromes, RNA virus diversity, anti-CRISPR protein discovery, and SARS-CoV-2 pathogenicity. These publications reflect his integrative approach to computational biology. Scientific Awards: NIH Distinguished Investigator (2019) Benjamin Franklin Prize for Open Access (2019) Doctor Honoris Causa, Wageningen University (2018) Georgy Gamow Prize (2018) Member, National Academy of Sciences (2016) Israel Pollak Lecture Award (2011) Leadership & Collaborations: He has chaired major conferences (e.g., Gordon Research Conference on Genomics) and served as Editor-in-Chief of Biology Direct and Associate Editor of Genome Biology and Evolution . His lab at NCBI includes researchers like Kira Makarova and Yuri Wolf.

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Ronald van RijView profile

Professor

Graz University of TechnologyAustria

Professor Ronald van Rij holds the position of Professor of Experimental Virology and Head of the Laboratory of Experimental Virology at Radboud University Medical Center in Nijmegen, Netherlands. He also serves as a Guest Professor at the University of Pavia, Italy. His research focuses on antiviral mechanisms in insects, particularly the roles of RNA interference (RNAi) and piRNA pathways in Drosophila melanogaster and Aedes aegypti mosquitoes. He has pioneered studies on viral defense in insects and vector competence, with translational work on antiviral compounds against pathogens like Zika and SARS-CoV-2 through the international 'COVID Moonshot' project. Education includes a PhD from the University of Amsterdam (2002) and postdoctoral fellowships at UCSF (USA) and the Hubrecht Institute (Netherlands). He has received prestigious grants such as ERC Consolidator and VICI awards, and was honored as Lecturer of the Year (2019) and PhD Supervisor of the Year (2017). Awards: ERC Proof of Concept Grant (2020), NWO VICI (2017), ERC Consolidator (2014), NWO VIDI (2008), EMBO Fellowship (2002). Teaching: Coordinates courses on virology, non-coding RNA, and innate immunity at Radboud University. Labs: Manages a BSL-3 facility for studying vector-borne pathogens in mosquitoes. His work bridges basic science and translational medicine, with emphasis on small RNA pathways and arbovirus control.

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Guy JoosView profile

Professor

Graz University of TechnologyAustria

Guy Joos is a Full Professor of Medicine at the Faculty of Medicine and Health Sciences, Ghent University , Head of the Department of Respiratory Medicine at Ghent University Hospital, and serves as Director of Research (Vice-Dean) at Ghent University since 2017. His academic career spans over three decades, with key roles including Chair of the Department of Internal Medicine (2014-2018) and ongoing leadership in respiratory research since 1999. Born in Ostend, Belgium (1956) M.D. and Ph.D. from Ghent University Board-certified in Internal and Pulmonary Medicine Prof Joos specializes in translational and clinical research on asthma and COPD , focusing on airway immunology, pharmacology, and pollution effects. His work at the Translational Lab for Obstructive Pulmonary Diseases has produced over 250 peer-reviewed publications with an h-index of 53. His research explores indirect bronchial provocation, miRNA expression in asthma subtypes, and ChemR23 signaling in pollutant-induced inflammation. Recent publications highlight interactions between innate lymphoid cells , TH2 responses , and air pollution . He has led pivotal clinical trials like the AZISAST study on macrolides in non-eosinophilic asthma. Fellow of European Respiratory Society (2014) Honorary Member of Lithuanian Society of Pulmonology (2012) Royal Academy of Medicine prizes (2004, 1995, 1988) Prof Joos has supervised 16 Ph.D. students since 1998, contributed to guidelines like the ERS Task Force on Indirect Challenges , and held editorial roles at journals including Respiratory Research and American Journal of Respiratory and Critical Care Medicine . He served as President of the European Respiratory Society (2016-2017) and the Belgian Thoracic Society (2010-2012).

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Johann BauersachsView profile

Professor

Graz University of TechnologyAustria

Professor Johann Bauersachs serves as Full Professor and Director of the Department of Cardiology and Angiology at Hannover Medical School (MHH) since 2010, with a distinguished career in cardiovascular research and clinical cardiology. He is a Fellow of the American Heart Association, European Society of Cardiology, and Heart Failure Association, and holds leadership positions including Chair of the HFA Committee on Peripartum Cardiomyopathies and Spokesperson of the DFG-funded Clinical Research Group KFO 311. His primary research interests focus on acute and chronic heart failure , acute coronary syndromes , left ventricular healing and remodeling , and the pathophysiology and treatment of peripartum cardiomyopathy . His work particularly emphasizes aldosterone and mineralocorticoid receptor-mediated mechanisms and the role of non-coding RNAs in cardiovascular disease. With over 1,133 publications and impressive H-indices (107 in Web of Science, 135 in Google Scholar), his recent research has centered on microRNA-based therapies like the HF-REVERT trial with CDR132L and the DIGIT-HF study investigating digitoxin for advanced heart failure. His most recent publications (2023-2024) demonstrate a clear trajectory toward translational research bridging molecular mechanisms with clinical applications, particularly in heart failure management. Key themes include the synergistic effects of SGLT2 inhibitors with mineralocorticoid receptor antagonists, novel therapeutic approaches for peripartum cardiomyopathy, and innovative diagnostic and treatment strategies for heart failure with preserved ejection fraction. Highly cited researcher in Clinical Medicine (Clarivate, 2023) ScholarGPS Highly Ranked Scholar (2022) Silver Badge of Honour, German Cardiac Society (2021) Paul-Morawitz-Award, German Cardiac Society (2018) Bernard and Joan Marshall Distinguished Investigator Award (2012) Parmley-Award, American College of Cardiology (2006) As Principal Investigator of multiple clinical trials including HF-REVERT and DIGIT-HF, Professor Bauersachs has secured significant funding from organizations including the Deutsche Forschungsgemeinschaft (DFG) and the Federal Ministry of Education and Research. His laboratory at MHH (Building I3) focuses on cardiac wound healing and remodeling after ischemia, with particular emphasis on mineralocorticoid receptor function in myeloid cells. He also serves in editorial capacities including Deputy Editor of the European Heart Journal and Associate Editor of Cardiovascular Research, while maintaining active advisory roles with Cardior Pharmaceuticals and Heartbeat.bio.

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Pascale RombyView profile

Researcher

Graz University of TechnologyAustria

Pascale Romby is a leading French molecular biologist and CNRS Researcher based at the Institute of Molecular and Cellular Biology (IBMC) in Strasbourg. She serves as Director of CNRS Unit UPR 9002 since 2016 and Team Leader of the 'Bacterial regulatory RNAs and mRNAs' group since 2004. Specializes in RNA biology and bacterial gene regulation Current focus on RNA-protein interactions and stress response networks Member of international/national scientific societies Active editorial and supervisory roles Research Interests : Romby's work centers on regulatory RNAs in bacteria, particularly their roles in virulence, stress responses, and host-pathogen interactions. Her team investigates RNA degradation machineries, translation control mechanisms, and the impact of small RNAs on bacterial persistence and metabolic adaptation. Publications Trends : Her recent work focuses on RNA targetome mapping in Gram-positive pathogens, ribosome structure-function relationships, and multi-layered regulatory networks controlling bacterial virulence. These studies employ biochemical, structural, and systems biology approaches. Scientific Honors : Recipient of the prestigious Pasteur Medal (2018) Langevin Prize by French Academy of Sciences (2010) CNRS Silver Medal (2006) and Bronze Medal (2003) FEBS Fellowship (1984) and Choucroun Prize (1984) Supervision & Leadership : Has mentored 15 PhD students, 10 postdocs, and 23 visiting researchers. Organized two major Jacques Monod Conferences on RNA regulation and delivered over 45 invited seminars worldwide.

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Sebastian FalkView profile

Associate Professor

University of ViennaAustria

Sebastian Falk is an Associate Professor at the Max Perutz Labs, part of the University of Vienna, within the Department of Structural and Computational Biology. His research focuses on the biogenesis and action of small RNAs, particularly piRNAs, employing structural biology and biochemical approaches to elucidate molecular mechanisms. He received the prestigious EMBO Young Investigator award in 2022. His lab investigates RNA surveillance pathways, mRNA splicing, and the interplay between RNA processing and degradation. Key projects include studying the MTR4-NRDE2-CCDC174 complex and piRNA processing factors in C. elegans. Falk has organized major symposia on RNA biology and contributed to high-impact publications in journals like Nature and Nucleic Acids Research . EMBO Young Investigator (2022) Grants: 'Characterization of piRNA processing factors in C. elegans' (2023-2026)

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Gioacchino NatoliView profile

Professor

Graz University of TechnologyAustria

Gioacchino Natoli is a Professor of Biochemistry at Humanitas University, School of Medicine, Milan, and serves as a Group Leader at the European Institute of Oncology (IEO) where he heads the Transcriptional Control in Inflammation and Cancer research program. Elected to the Academy of Europe in 2017 and an EMBO member since 2013, his work bridges molecular oncology and immunology with significant contributions to epigenetic regulation. Education: Medical Doctor with honors, University of Rome, La Sapienza (1991) Residency in Internal Medicine, University of Rome, La Sapienza (1991-1996) Post-doctoral fellow, University of California San Diego under Prof. Michael Karin (1998-2000) His research centers on transcriptional and epigenetic mechanisms governing innate immunity and cancer, with specific expertise in macrophage biology, chromatin dynamics, and non-coding transcription. He investigates how enhancers and cis-regulatory elements control inflammatory gene expression programs and maintain cellular identity in tumorigenesis, employing genomic and biochemical approaches to dissect disease-relevant pathways. Analysis of his publication record reveals consistent focus on epigenetic control of inflammation-cancer crosstalk, with landmark studies on histone modifiers (Jmjd3, Mll4) and enhancer functionality published in Nature Immunology, Cell, and Molecular Cell. His work demonstrates how environmental signals are integrated at genomic loci to shape immune responses. Scientific Awards: European Research Council (ERC) Advanced Grant (2016-2021) EMBO member (2013) European Research Council (ERC) Advanced Grant (2011-2015) Chiara D’Onofrio prize for Italian researchers below 43 years (2009) Marie Curie Excellence Grant (2007-2010) Damon Runyon-Walter Winchell Cancer Research Fund Long Term Fellowship (1998-2000) Natoli has secured substantial competitive funding including dual ERC Advanced Grants to investigate transcriptional networks linking inflammation and cancer. His laboratory at IEO mentors doctoral candidates and postdoctoral researchers, fostering expertise in genomic technologies and molecular pathogenesis while advancing therapeutic target discovery. He leads the Transcriptional Control in Inflammation and Cancer program within IEO's research infrastructure, utilizing advanced sequencing and imaging platforms to map regulatory landscapes in disease models. The group collaborates extensively with clinical teams to translate mechanistic insights into oncology applications.

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Botond RoskaView profile

Professor

Graz University of TechnologyAustria

Botond Roska is a Professor at the Faculty of Science, University of Basel, Switzerland, and previously served as Professor at the Faculty of Medicine, University of Basel since 2014. He is the Founding Director of the Institute of Molecular and Clinical Ophthalmology Basel (IOB), established in 2018. His academic career includes serving as Senior Group Leader (2010-2019) and Junior Group Leader (2005-2010) at the Friedrich Miescher Institute in Basel. Born in 1969 in Hungary, Roska obtained his M.D. at the Semmelweis Medical School, a Ph.D. in neurobiology from the University of California, Berkeley, and studied genetics and virology as a Harvard Society Fellow at Harvard University and Harvard Medical School. Dr. Roska's research focuses on understanding the visual system at the level of cell types and circuits, with particular emphasis on the retina, thalamus, and cortex. His work aims to find ways to repair visual dysfunction and restore vision in blind individuals. He investigates how the organization of cell types and circuits in the nervous system, when combined with cellular engineering, can be used to design new therapies to fight blindness. Analysis of Roska's recent publications reveals a strong focus on single-cell resolution studies of the retina, development of gene therapy approaches for vision restoration, and detailed mapping of visual neural circuits. His work spans multiple disciplines including neuroscience, ophthalmology, genetics, and molecular biology, with a clear translational focus toward developing treatments for visual impairments. Dr. Roska has received numerous prestigious awards throughout his career: 1997: Fulbright Fellow 2001: Bearden Memorial Award for Biophysics 2002: Harvard Junior Fellow 2006: Marie Curie Excellence Grant 2009: EMBO Young Investigator 2010: ERC Starting Grant and VIVA Award 2011: Alcon Award and EMBO membership 2013: Alfred Vogt Award 2015: ERC Advanced Grant 2016: Cogan Award 2018: Bressler Prize and Alden W. Spencer Award 2019: Louis-Jeantet Prize, Order of Saint Stephen of Hungary, Cloëtta Prize, and Semmelweis Budapest Award 2020: ERC Advanced Grant and Körber European Science Prize 2024: Wolf Prize in Medicine (for sight-saving and vision restoration to blind people using optogenetics) As a principal investigator, Roska has secured significant research funding including multiple ERC grants (Starting Grant in 2010, Advanced Grants in 2015 and 2020), a Marie Curie Excellence Grant, and the VIVA Award. His laboratory has mentored numerous researchers who have gone on to publish impactful work in top-tier journals. The collaborative nature of his research is evident from the multi-institutional authorship of his publications. Dr. Roska founded and directs the Institute of Molecular and Clinical Ophthalmology Basel (IOB), which brings together basic scientists and clinicians to develop treatments for eye diseases. His laboratory employs advanced techniques including single-cell analysis, viral vector engineering, optogenetics, and neural circuit mapping to advance our understanding of the visual system and develop novel therapeutic approaches.

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Hermona SoreqView profile

Professor

Graz University of TechnologyAustria

Hermona Soreq is a Professor in the Department of Biological Chemistry at The Hebrew University and a founding member of the Edmond and Lily Safra Center for Brain Sciences (ELSC). Her career spans leadership roles as Dean of the Faculty of Mathematics and Natural Sciences (2005-2008), Vice Dean for R&D (2002-2005), and Head of multiple institutes, including the Eric Roland Center for Neurodegenerative Diseases (2000-2005). Current Positions: Professor of Molecular Neuroscience, ELSC Founding Member Previous Leadership: Dean, Vice Dean, Institute/Department Head Her research focuses on the molecular biology and genomics of acetylcholine signaling, particularly microRNA regulation (CholinomiRs) in stress-induced cognitive decline and neurodegenerative diseases. She pioneered the development of Quantum Dot labeling tools for cholinesterases. Her publications include 10 high-impact works (e.g., Science , Nature , PNAS ) spanning: MicroRNA-132 in inflammation and cognition Cholinergic signaling in stress and trauma RNA metabolism in Alzheimer’s disease MicroRNA-target interactions in metabolic disorders Scientific honors include: Advanced ERC Award (2013-2018) ILANIT-Katzir Prize (2017) Historic contributions to cholinergic mechanisms

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Gianluigi CondorelliView profile

Professor

Graz University of TechnologyAustria

Gianluigi Condorelli is a Professor of Cardiology at Humanitas University (2015-present) and Director of the Department of Cardiovascular Medicine at Humanitas Research Hospital. He has held numerous academic positions, including Full Professor at University of Milan "Bicocca" (2008-2012), Adjunct Full Professor at UCSD (2009-2012), and Chairman of the Department of Medicine at CNR (2006-2012). His career spans institutions in Italy, the United States, and the UK, with a focus on molecular cardiology and epigenetics. MD (1989) and PhD (1994) from Italian universities Specialty in Cardiology (1998) His research focuses on the molecular mechanisms of cardiovascular diseases, particularly heart failure, with emphasis on non-coding RNAs and epigenetics. Additional research lines include cardiomyopathies, cardiovascular biomarkers (microRNAs, lncRNAs), and immunity in cardiovascular disease. He has over 200 publications and an h-index of 73. Condorelli has received prestigious awards including the European Research Council Advanced Grant (2012), Valsalva Award for Cardiovascular Diseases (2008), and Outstanding Investigator Award from the European Society of Cardiology (2010). His editorial roles include Senior Guest Editor for Circulation and past Associate Editorships for multiple journals. He has served on international academic panels for professorships at institutions including Technical University of Munich, The Cleveland Clinic, and University of Manchester, while also reviewing grants for organizations such as the American Heart Association, European Research Council, and Wellcome Trust. Condorelli is actively involved in peer-review activities for high-impact journals like Nature , Circulation , and JACC .

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Lehtimäki TerhoView profile

Professor

Graz University of TechnologyAustria

Terho Lehtimäki is a Professor and Head of the Department of Clinical Chemistry at Tampere University's Faculty of Medicine and Health Technology. He also serves as Chief Physician at Fimlab Laboratories, a major clinical laboratory in Finland. His academic roles include being a docent in medical biochemistry and clinical chemistry, and he holds an eMBA degree. His research focuses on cardiovascular disease biomarkers, atherosclerosis, omics technologies, and genetic/epigenetic factors influencing complex traits. He leads major studies like the Tampere Vascular Study and contributes to over 35 international consortia. With 1200+ peer-reviewed publications and an H-index of 147, his work has driven discoveries in over 5000 genetic variants. Notable recognitions include membership in Academia Europaea and the University of Tampere Science Prize. Education & Career MD/PhD (1992) Docent in Medical Biochemistry (1996, University of Tampere) Docent in Clinical Chemistry (2003, University of Eastern Finland) eMBA (2013) Research Interests Cardiovascular biomarkers for risk prediction Omics-based systems biology approaches Functional genetics of complex traits Epigenetic inheritance mechanisms Multimodal cohort studies (e.g., Young Finns Study) Publications & Impact His work spans Nature, Science, and NEJM, with key contributions to understanding atherosclerosis biology, genetic risk factors, and clinical translation of omics data. Recent trends emphasize multi-omics integration and precision medicine applications. Awards & Leadership Over €15M in grant funding 3 spin-off companies Scientific leadership roles in >35 international initiatives Reviewer for 50+ journals and 15 funding agencies Teaching & Mentorship Trained over 60 PhD/MSc students, many now leading academic and clinical roles. Active in problem-based learning methodologies at Tampere University's Center of Excellence. Labs & Teams Directs the Clinical Chemistry Department's research group, collaborating closely with Fimlab Laboratories and international networks like the European Eye Consortium.

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Mihaela ZavolanView profile

Professor

Graz University of TechnologyAustria

Mihaela Zavolan is a Full Professor at the Biozentrum, University of Basel, Switzerland, where she has held continuous faculty appointments since 2003 (Assistant Professor 2003-2008, Associate Professor 2008-2014, Full Professor 2014-present). She simultaneously serves as a Group Leader at the Swiss Institute of Bioinformatics since 2004, directing research on RNA regulatory networks. Her educational background includes: PhD in Computer Science, University of New Mexico (1996-1999) M.Sc. in Computer Science, University of New Mexico (1994-1996) M.D., University of Medicine and Pharmacy, Timisoara, Romania (1986-1992) Dr. Zavolan's research centers on computational RNA biology , with pioneering work in microRNA mechanisms, RNA splicing, RNA-binding proteins, and pre-mRNA 3' end processing. Her group integrates advanced computational modeling with high-throughput experimental data to dissect post-transcriptional gene regulation networks. Key methodological contributions include quantitative analysis of CLIP techniques and biophysical models of miRNA-mRNA interactions. Analysis of her publication record reveals consistent focus on developing and applying computational frameworks for RNA regulatory networks, with increasing emphasis on genome-wide mapping of RNA-protein interactions and quantitative modeling of regulatory dynamics. Her work bridges molecular biology, genomics, and systems biology through innovative algorithm development. Her major scientific awards include: ERC Starting Grant (2012) Young Investigator of EURASNET (2006-2009) Lita Annenberg Hazen Presidential Fellowship, The Rockefeller University (2001-2003) Presidential Fellowship, The Rockefeller University (2001) Burroughs Wellcome Fellow, The Rockefeller University (2000) Dr. Zavolan has secured competitive research funding including the ERC Starting Grant and maintains active grant support through her group leadership positions. She serves on editorial boards of Genome Biology, Bioinformatics, BMC Molecular Biology, and Cells, and has organized major conferences including the European Conference on Computational Biology (2012) and Computational RNA Biology Conference (2014). She leads parallel research groups at the Biozentrum (Computational and Systems Biology) and Swiss Institute of Bioinformatics (RNA regulatory networks), employing interdisciplinary teams that combine computational biology, molecular biology, and high-throughput data analysis to investigate RNA-mediated gene regulation mechanisms.

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Irene BozzoniView profile

Professor

Graz University of TechnologyAustria

Irene Bozzoni serves as Full Professor of Molecular Biology at Sapienza University of Rome, a position held continuously since 1994 following her promotion from Associate Professor (1986-1994). Her academic career began with research appointments at Rome's Center for Nucleic Acid Research (CNR) and a post-doctoral fellowship at University of Zurich's Institute of Molecular Biology. Her research expertise centers on non-coding RNA mechanisms with specific focus: Mechanism and regulation of non-coding RNA function in mammalian cells Role of non-coding RNA in gene expression control Long non-coding RNA biology Therapeutic RNA applications This work bridges molecular and cellular biology, advancing understanding of RNA-mediated genetic regulation. Her contributions have earned significant recognition: Accademia Nazionale dei Lincei Prizes (2003, 2006) Sapienza Ricerca Award (2010) Membership in European Molecular Biology Organization (EMBO) Membership in Academia Europaea As an ordinary member of the Academy of Europe's CELL & DEVELOPMENTAL BIOLOGY section since 2002, she maintains active engagement in international scientific discourse while continuing her research leadership at Sapienza University.

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Benjamin ColtmanView profile

Researcher

University of ViennaAustria

Dr. Benjamin Coltman is an active researcher affiliated with the Centre for Microbiology and Environmental Systems Science and the Department of Microbiology and Ecosystem Science . His work focuses on molecular biology, genomics, and RNA sequencing, with particular emphasis on long non-coding RNAs (lncRNAs) in yeast biotechnology. Research Areas: Genetics and molecular biology, RNA sequencing, microbial systems science, bioinformatics, and biotechnology applications. Recent Publication: Lead author on a 2025 Computational and Structural Biotechnology Journal article analyzing lncRNA functionality in Komagataella phaffii . Collaborations: Engaged in external collaborations across academic institutions, focusing on microbial genomics and biotechnological applications.

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Józef DulakView profile

Professor

Graz University of TechnologyAustria

Józef Dulak is a Professor and head of the Department of Medical Biotechnology at the Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland. He also serves as vice-president of the Committee of Biotechnology of the Polish Academy of Sciences. Current positions: Professor & Head (Jagiellonian University); Vice-president (Polish Academy of Sciences) Past roles: Vice Dean for Research; Coordinator of CNRS-Jagiellonian University LIA; President of European Vascular Biology Organisation (2013-2017) Research interests include vascular biology, stem cell regulation, molecular inflammation, cardiovascular diseases, and gene/cell therapy. His work focuses on the Nrf2-HO-1-microRNA pathways in reparative processes across acquired and inherited diseases, particularly Duchenne muscular dystrophy. Scientific contributions span over 270 articles (10k+ citations, h-index 55), a patent on stem cell mobilization, and 13M+ Euro in grants (including two MAESTRO grants). His publications emphasize microRNA mechanisms , hematopoietic stem cell dynamics , and HO-1-based therapies . Key journals: JCI Insight , EMBO Reports , Cardiovascular Research Collaborations: CNRS (France), European projects, US/German/Austrian institutions Awards include the Frederic Leloir Award, Tadeusz Browicz Award, and multiple Rector/Jagiellonian University honors. He holds honorary doctorates and is a Full Member of the Polish Academy of Arts and Sciences.

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