Find Academic Supervisors

• Pharmacology
• Toxicology
• Clinical Pharmacy
• +9 more

Prof. Dr. Robert Lukowski is a faculty member at the University of Tübingen, affiliated with the Faculty of Science, Department of Pharmacy and Biochemistry, and leads the research group in Pharmacology, Toxicology and Clinical Pharmacy. He is based at the Institut für Pharmazie, focusing on experimental pharmacology with a strong emphasis on cGMP signaling and ion channel biology. University: University of Tübingen School: Faculty of Science Department: Pharmacy and Biochemistry, Pharmaceutical Sciences, Pharmacology, Toxicology and Clinical Pharmacy Email: robert.lukowski@uni-tuebingen.de His research centers on the role of cGMP and potassium channels (BK, Slack, KCa3.1) in cardiovascular protection, cancer metabolism, and neurological functions. He investigates how these channels regulate cellular signaling in conditions such as ischemia, fibrosis, and neurodegeneration. His work bridges molecular pharmacology with translational applications in cardiology, oncology, and neuroscience. The recent publications show a strong trend in understanding ion channel function in disease models, particularly in myocardial protection, metabolic reprogramming in cancer, and pain/itch pathways. The use of genetically encoded biosensors and mouse models is a hallmark of his research approach. Topics span from mitochondrial function to synaptic plasticity and immune cell signaling. Scientific Commentary and Recognition: Regular contributor to Faculty Opinions (F1000), recommending high-impact studies in cardiovascular and molecular pharmacology. Advising and Research Leadership: Leads a multidisciplinary team including postdoctoral researchers, PhD candidates, and laboratory staff, indicating active mentorship and grant-funded research. His collaborations span multiple institutions and involve advanced imaging, molecular biology, and physiological assays. Laboratory and Research Environment: The "Experimentelle Pharmakologie" lab at Auf der Morgenstelle 8 is equipped for cutting-edge research in signal transduction, utilizing biosensors, transgenic models, and functional assays to study cGMP and ion channel dynamics in health and disease.

• Epigenetics
• CRISPR-Cas9 Technology
• Cell Fate Reprogramming
• +3 more

V. Baumann is a researcher and co-author of the commentary article Seeking fate—CRISPRa screens reveal new neural lineage and reprogramming factors (2019), published in Stem Cell Investigation . His work focuses on CRISPR-based transcriptional activation (CRISPRa) screens to identify neuronal promoting factors and their synergistic interactions. Key research areas include: Epigenetics : Role of chromatin barriers and DNA methylation in transcriptional activation. Cell Fate Reprogramming : Mechanisms for converting embryonic stem cells and terminally differentiated cells into neurons. CRISPR-Cas9 Technology : Optimization of gene activation strategies using SunTag and dCas9 systems. Neural Development : Identification of novel transcription factors driving neurogenesis. His collaborative article Targeted removal of epigenetic barriers during transcriptional reprogramming (2019) in Nature Communications further explores chromatin remodeling in reprogramming efficiency.

Boyan BonevView profile

Assistant Professor

• epigenetics
• brain development
• single-cell genomics
• +7 more

Dr. Boyan Bonev is a Research Group Leader at the Institute of Epigenetics and Stem Cells (IES) within Helmholtz Center Munich, where he leads the Bonev Lab Brain Epigenomics. His lab is located at the Pioneer Campus in Martinsried, near the Max-Planck institutes for Biological Intelligence and Biochemistry. Bonev holds a position as GSN temporary or junior faculty and has established himself as an emerging leader in epigenetic research of brain development. His research focuses on decoding the epigenetic mechanisms of cell fate decisions in the mammalian brain, with particular emphasis on cerebral cortex development. Bonev's interdisciplinary approach combines single-cell multiomics, lineage tracing, high-throughput CRISPR perturbations, computational biology, and human cerebral organoids. His work investigates how cellular identity in the cortex is established through the interplay between transcriptional regulators, cis-regulatory elements, and the chromatin landscape within 3D nuclear architecture. His lab has made significant contributions to understanding how chromatin remodellers and epigenetic regulation determine fate choices in the cortex and how non-coding genetic variants relate to neurodevelopmental disorders. Bonev's research group has demonstrated impressive growth, with numerous postdocs and PhD students joining since the lab's establishment in 2019. His publications reveal a strong focus on 3D genome organization during neural development, with recent work advancing single-cell multimodal profiling techniques. His research trajectory shows increasing sophistication from early work on microRNA regulation to current cutting-edge multi-omics approaches examining epigenetic mechanisms at unprecedented resolution. His scientific achievements have been recognized with prestigious awards including the EMBO Young Investigator Award (2022) and ERC Consolidator Grant (2022), which provides €2 million over 5 years. He has also secured an ERA-NET Neuron grant (2021) and received "The Great Advances in French Biology 2018" from the French Academy of Sciences. These awards reflect the significance of his work in epigenetics and brain development. Bonev actively mentors PhD students and postdoctoral researchers, with his team expanding rapidly since the lab's founding. His current research program, funded by the ERC Consolidator Grant, investigates the molecular mechanism and functional contribution of epigenetic rewiring during cortical development, combining single-cell multiomics, high-throughput reporter assays, and functional CRISPR perturbations. The Bonev Lab maintains strong collaborative relationships, including work with Prof. Magdalena Götz on epigenome remodeling in direct neuronal reprogramming. The Bonev Lab operates as a highly interdisciplinary team at the intersection of developmental neurobiology, single-cell genomics, mouse genetics, CRISPR technology, and computational biology. The lab is developing novel tools for simultaneous multimodal epigenome profiling and perturbations in single cells, positioning itself at the forefront of epigenetic research methodology. Located within the high-tech Pioneer Campus in Martinsried, the lab benefits from proximity to leading research institutions including the Max-Planck institutes.

Michael Nip HallView profile

Professor

• Molecular Biology
• Cell Growth Control
• Signal Transduction
• +5 more

Michael Nip Hall is a distinguished American-Swiss molecular biologist and Professor at the Biozentrum of the University of Basel, Switzerland. He has held this position since 1992, following his appointment as Assistant Professor in 1987. Hall previously held positions at the University of California, San Francisco and conducted postdoctoral research at the Pasteur Institute in Paris. Dr. Hall earned his B.S. in Zoology from the University of North Carolina at Chapel Hill in 1976 and his Ph.D. from Harvard University in 1981. His doctoral research focused on "Genetic studies on the regulation of the major outer membrane porin proteins of Escherichia coli K-12" under advisor Thomas J. Silhavy. Professor Hall is a pioneer in the field of cell growth regulation and is best known for discovering the TOR (Target of Rapamycin) protein, which is central to understanding cell growth control. His research focuses on the molecular mechanisms that control growth and metabolism in health and disease, with particular emphasis on the TOR signaling pathway. Hall studies TOR signaling using multiple model systems, including yeast (Saccharomyces cerevisiae), mammalian cells, mice, and human tumors, employing biochemical, genetic, and cell biological approaches. His publication record demonstrates a strong focus on mTOR signaling, cancer metabolism, and cellular growth regulation. Recent work has explored connections between mTOR signaling and various disease states including cancer, metabolic disorders, and aging. His research has increasingly incorporated multi-omics approaches to understand complex disease mechanisms. Balzan Prize for Biological Mechanisms of Ageing (2024) Grande Médaille, French Academy of Sciences (2023) Sjöberg Prize (2020) Albert Lasker Award for Basic Medical Research (2017) Canada Gairdner International Award (2015) Breakthrough Prize in Life Sciences (2014) As Vice Director of the Biozentrum (2002-2009, 2013-2016) and Chairman of the European Molecular Biology Organization Council (2021-2022), Hall has played significant leadership roles in academic research. He currently serves on the Board of Trustees of the Louis-Jeantet Foundation and has received continuous research funding including an ERC Synergy Grant (2014-2020). His laboratory continues to investigate fundamental mechanisms of cell growth with implications for understanding and treating numerous human diseases. Professor Hall leads an active research group at the Biozentrum focusing on TOR signaling and its role in cell growth control. His laboratory employs a multidisciplinary approach, combining biochemical, genetic, and cell biological techniques to unravel the complex mechanisms of TOR signaling in various model systems.

Sandra SchickView profile

Researcher

• Epigenetics
• Chromatin Remodeling
• Genome Stability
• +7 more

Sandra Schick is a researcher at the Institute of Molecular Biology (IMB) in Mainz, Germany, with leadership roles since 2020. She holds a PhD in Molecular Biology (2016) and a Master's in Biomedicine from Johannes Gutenberg University. Her research focuses on chromatin regulation through BAF complexes, including their role in epigenetics , genome stability , and disease mechanisms . She employs genomics , proteomics , and CRISPR/Cas9 in mouse and human models. Scientific awards include the Life Science Research Award (2019) and scholarships from the Bayer Foundation (2009) and Keystone Meeting (2018). Her recent publications investigate chromatin remodeling in cancer and aging.

Mathias F. WernetView profile

Professor

• Neural Circuits
• Polarization Vision
• Drosophila Melanogaster
• +3 more

Prof. Mathias F. Wernet is a Professor of Neurobiology at the Freie Universität Berlin, leading the Wernet Group focused on neural circuitry in Drosophila melanogaster . His research explores visual processing mechanisms, particularly polarization vision and navigation, using genetic, behavioral, and neuroanatomical approaches. He coordinates teaching in neurobiology modules, including courses on insect biology and advanced topics in neural circuits. His lab investigates how neural circuits integrate sensory inputs to guide behavior, with emphasis on the medulla neuropil and retinal mosaics. Research Themes: Neural circuits, polarization vision, Drosophila genetics, visual navigation. Teaching Roles: Leads neurobiology lectures, practicals, and advanced modules for undergraduates and master’s students. Lab Members: Supervises PhD candidates and postdocs in projects involving optogenetics, connectomics, and behavioral assays. Key findings include identifying modality-specific circuits for skylight orientation and uncovering synaptic adaptations in polarization-processing neurons. His group pioneered modular flight arena designs to study real-time navigation responses under polarized light stimuli.

Kristen KozielskiView profile

Assistant Professor

• Neuroengineering
• Materials Science
• Biomaterials
• +5 more

Prof. Kristen Kozielski is an Assistant Professor of Neuroengineering Materials at the Technical University of Munich (TUM), holding a position in the Department of Electrical and Computer Engineering and serving as Program Director for TUM's Elite Master’s Program in Neuroengineering. She leads the Neuroengineering Materials group, focusing on developing minimally invasive neurotechnologies using advanced materials. Her research integrates materials science, nanotechnology, and neurobiology to engineer wireless interfaces for neural communication and stimulation. Dr. Kozielski earned her PhD in Biomedical Engineering from Johns Hopkins University and completed postdoctoral work at the Max Planck Institute for Intelligent Systems. Before joining TUM in 2021, she was a group leader at the Karlsruhe Institute of Technology (2019–2021). Her career has been marked by prestigious awards, including grants from the Michael J. Fox Foundation and fellowships from the NIH and Whitaker International Program. Her research emphasizes magnetoelectric nanoparticles for deep brain stimulation, bioreducible polymeric nanoparticles for cancer therapy, and novel methods for noninvasive neural interfacing. Her work bridges disciplines to address challenges in neuroengineering, such as improving drug delivery to the brain and designing smart materials for clinical applications. Key achievements include demonstrating wireless deep brain stimulation in animal models and developing nanoparticle systems that target glioblastoma stem cells. Her publications span topics like neural stimulation modeling, endosomal pH regulation in cancer, and multiscale nanoparticle analysis. She collaborates across TUM’s School of Computation, Information, and Technology, fostering interdisciplinary innovation. Prof. Kozielski actively mentors students and researchers, contributing to TUM’s training programs in neuroengineering. Her lab’s focus on translational research aims to bridge gaps between material science and clinical applications in neurology and oncology.

• Stem Cell Engineering
• Molecular Pathways of Stem Cell Self-Renewal
• Lineage Commitment
• +5 more

Professor Konstantinos Anastassiadis serves as the Chair for Stem Cell Engineering at the Biotechnology Center (BIOTEC), which is part of the Center for Molecular and Cellular Bioengineering (CMCB) at Dresden University of Technology. He has held this professorship since 2016, following his appointment as Research Group Leader for Stem Cell Engineering at BIOTEC from 2004-2016 and Junior Group Leader at the Center for Regenerative Therapies Dresden (CRTD) from 2006-2011. Dr. Anastassiadis earned his Dr. sc. agr. from TU Berlin in 1993, followed by postdoctoral work at TU Munich (1993-1995), EMBL Heidelberg (1996-2001), and BIOTEC, TU Dresden (2002-2003). His academic journey reflects a strong foundation in molecular biology and genetics that has shaped his current research focus. The research interests of Prof. Anastassiadis center on unraveling the molecular pathways that regulate self-renewal and lineage commitment of stem cells, with particular focus on the molecular mechanisms involved in cellular reprogramming. His lab works with various stem cell types including mouse and human embryonic stem cells (mES, hES), neural stem cells (NSCs), mesenchymal stromal cells (MSCs), and induced pluripotent stem cells (iPS). A significant portion of his work involves developing and applying genetic engineering tools to address fundamental questions in stem cell biology. His research has particularly concentrated on the role of histone 3 lysine 27 demethylases UTX (KDM6A) and UTY (KDM6C) in embryonic development and hematopoiesis. Analysis of Prof. Anastassiadis's recent publications reveals a strong focus on stem cell regulation, epigenetic mechanisms, and genetic engineering applications. His work spans multiple model systems including mouse models, human stem cells, and other organisms. A recurring theme is the investigation of chromatin modifiers (particularly histone methylation complexes like MLL/SET proteins) and their roles in development, disease, and stem cell maintenance. His lab has made significant contributions to developing genetic engineering tools including codon-optimized recombinases (Flp, Dre, Vika), transposon-mediated BAC transgenesis, and CRISPR-associated protocols. Prof. Anastassiadis is actively involved in teaching for the international Master's programs in Molecular Bioengineering and Regenerative Biology and Medicine (RegBioMed) at CMCB. He teaches courses including Stem Cell Engineering (every winter semester) and Stem Cells, Development and Regeneration, as well as supervising the Genome and Stem Cell Engineering lab course. The Anastassiadis Group operates within the Biotechnology Center at TU Dresden, where they maintain facilities for stem cell culture, genetic engineering, and molecular analysis. Their research integrates approaches from molecular biology, genetics, epigenetics, and bioengineering to address fundamental questions about stem cell behavior and to develop new tools for stem cell research and potential therapeutic applications.

• Translational Oncology
• Skin Cancer
• Tumor Microenvironment
• +4 more

Prof. Dr. Dr. Jürgen Becker is Head of the Department of Translational Skin Cancer Research at the University of Duisburg-Essen's Faculty of Biology and leads the Translational Oncology group at the West German Cancer Center (WTZ). He is affiliated with the German Cancer Research Center (DKFZ) and focuses on leveraging skin cancer's unique characteristics – early diagnosis and sequential progression – to study tumor biology and immunotherapy responses. His research integrates advanced methodologies including spatial transcriptomics, single-cell multiomics, micro-CT, and deep learning to analyze tumor microenvironments, heterogeneity, and biomarker discovery. Key interests include: Immunotherapy optimization for Merkel cell carcinoma and melanoma Tumor microenvironment dynamics and endogenous retrovirus activation Biomarker development for early diagnosis and treatment response DNA repair/DNA damage response inhibition strategies Becker leads significant clinical trials (ADMEC-O, IMMUNED) and maintains prospective biosample registries (MCC TRIM) to enable longitudinal studies. His publications emphasize translational insights in skin cancer, with recent work exploring immunotherapy biomarkers, Merkel cell polyomavirus mechanisms, and combinatorial therapies. He directs a research group at WTZ investigating tumor epidermotropism, neuroblastic transformation, and lesional microbiome impacts. Future projects include 3D tissue mapping via micro-CT and multi-omic integration of archived FFPE samples.

• Molecular Neuroscience
• Developmental Neuroscience
• Stem Cell Biology
• +4 more

Magdalena Götz is a Professor at Ludwig-Maximilians-Universität München and Director of the Institute of Stem Cell Research at Helmholtz Munich. She leads the Stem Cell Center Department and Neural Stem Cells research group, focusing on molecular mechanisms of neurogenesis and direct neuronal reprogramming. Chair of Physiological Genomics, LMU Biomedical Center Director, Institute of Stem Cell Research Head, Stem Cell Center Department Head, Neural Stem Cells Research Group Her research in molecular & developmental neuroscience explores neural stem cells, neurogenesis, brain injury repair, and direct neuronal reprogramming. Key discoveries include identifying radial glial cells as neural stem cells and pioneering glia-to-neuron conversion for brain repair. Recent work examines epigenetic remodeling, centrosome proteins, and human neural stem cell proteomics. Articles highlight advancements in neurogenesis mechanisms and therapeutic applications for brain injuries. Honors & Awards Gottfried Wilhelm Leibniz Prize (2007) Advanced ERC Grant (2014, 2020) Roger de Spoelberch Prize (2017) She mentors numerous PhD students and collaborates with institutions like GSN Scientific Board and Synergy Cluster. Her work bridges developmental biology with regenerative medicine, offering new hope for neurodegenerative diseases.

• Epigenetics
• Cancer Biology
• Neuroscience
• +5 more

Derrick Ong is an Assistant Professor at the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS). His academic career spans roles in research, editorial contributions, and grant-funded projects focused on cancer biology and epigenetics. Education: Ph.D. in Molecular Medicine (2011), Scripps Research Institute M.S. in Biological Sciences (2004), NUS B.S. (First Class Honors) in Chemistry & Biological Sciences (2003), NUS Research interests center on epigenetic regulation in cancer, particularly glioblastoma, with a focus on chromatin dynamics, metabolic stress, and redox biology. His work bridges molecular medicine with translational oncology. Recent publications highlight advancements in glioblastoma stemness, chromatin topology, nanoparticle-based therapies, and telomere biology. Key themes include epigenetic plasticity, mitochondrial dysfunction, and therapeutic vulnerabilities. Scientific Awards: NRF Fellowship (Singapore) Yong Loo Lin School of Medicine Research Excellence Award (2023) Active in peer review for journals like Advanced Science, Cell Death & Disease, and Oncogene. Leads grants from NUS, NUS Center for Cancer Research, and Singapore's Ministry of Education.

Tee Wee WeiView profile

Assistant Professor

• Chromatin Dynamics
• Epigenetics
• Cancer Research
• +3 more

Tee Wee Wei is an Assistant Professor at the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore. He is also a Principal Investigator at the Institute of Molecular and Cell Biology (IMCB), A*STAR, with affiliations to the NUS Centre for Cancer Research and the Translational Research Programme. Research Focus: Chromatin dynamics in disease epigenetics, targeting chromatin vulnerabilities in cancer, identifying epigenetic drivers of therapeutic resistance, and investigating early-embryonic factor reactivation in cancer cell plasticity. Regenerative Medicine: Exploiting chromatin plasticity to promote developmental potency (e.g., totipotency, stem cells, reprogramming). Technologies: Development and application of (epi)genomic tools for studying chromatin and gene regulation. Selected Scientific Awards: 2024 Yong Loo Lin School of Medicine Research Excellence Award 2022 EMBO Global Investigator 2016 Singapore National Research Foundation (NRF) Fellowship 2015 NIH Pathway to Independence Award (K99/R00) 2012 New York Stem Cell Foundation Druckenmiller Fellowship 2005 Cambridge Commonwealth Trust Award and Wellcome Trust PhD studentship Contact: phstee@nus.edu.sg

Karl-Klaus ConzelmannView profile

Professor

• Virology
• Molecular Biology
• Neurovirology
• +3 more

Karl-Klaus Conzelmann is a Professor at the Department of Virology, Ludwig-Maximilians-Universität München (LMU). His research focuses on negative-strand RNA viruses like rabies and measles, exploring their interaction with host cell machinery and applications in neuronal tracing and antiviral strategies . He employs reverse genetics and CRISPR-based editing to study virus replication and host-pathogen dynamics. His work spans virology, molecular biology, and neuroscience. Recent studies include synaptic tracing using rabies virus variants, immune evasion mechanisms in RNA viruses, and neurodegenerative disease modeling . He has contributed to COVID-19 vaccine development and understanding mitochondrial-ER interactions in astrocytes. Key trends in his publications involve CRISPR applications , innate immune antagonism by viral proteins, and neuronal circuit mapping . His studies often integrate virology with neurobiology , highlighting cross-disciplinary approaches. Scientific Awards: Loeffler-Frosch Prize of the German Society for Virology (1995) Ph.D. student fellowship, State of Baden-Württemberg (1985-1987) Conzelmann's lab has secured funding through DFG (Co260/5), SFB870, and SPP1665. His team collaborates on host-pathogen interaction and neurovirology projects, with a focus on viral genome engineering and interferon signaling .

Marko BrankatschkView profile

Researcher

• Lipid Metabolism
• Neurobiology
• Drosophila Genetics
• +3 more

Dr. Marko Brankatschk is a Guest Researcher at the Technical University of Dresden (TU Dresden), leading the Brankatschk Lab focused on neural-glial membrane biology and lipid metabolism in Drosophila melanogaster . His work examines how circulating lipids regulate temperature-dependent metabolism, blood-brain barrier function, and cognitive capacity in fruit flies through dietary and structural mechanisms. His research centers on lipid metabolism as a critical regulator of environmental adaptation, with key interests in neural-glial membrane dynamics , temperature-dependent foraging behavior , and systemic lipid signaling . The lab investigates how unsaturated lipids modulate biophysical membrane properties under thermal stress, how dietary sterols serve as metabolic cues, and how glial cells fuel neuronal metabolism via β-oxidation during metabolic challenges. This work bridges comparative physiology , membrane biophysics , and neurogenetics to understand conserved metabolic adaptation strategies. Analysis of his 15 most recent publications reveals dominant trends in regenerative lipidology (2024), glia-neuron metabolic coupling (2020-2023), and ecological lipid signaling (2019-2021). His work consistently employs Drosophila to model fundamental processes relevant to human metabolic diseases, with increasing focus on cross-tissue lipid transport and regenerative mechanisms. Dr. Brankatschk actively collaborates with international partners including Stefanie Schirmeier (University of Münster), Tatiana Sandoval-Guzmán (CRTD Dresden), Klaus Reinhardt (TU Dresden), Adam Dobson (University of Glasgow), and Anna Taubenberger (TU Dresden BIOTEC). His research is funded by European and German institutions, supporting investigations into lipid-driven physiological adaptations. The Brankatschk Lab operates within TU Dresden's biotechnology ecosystem, leveraging the university's Center for Regenerative Therapies (CRTD) and BIOTEC infrastructure. Current projects explore lipid-mediated regeneration in Drosophila and Ambystoma mexicanum , neural membrane plasticity under thermal stress, and metabolic interactions in nutrient-deprived nervous systems.

• Stem Cell Research
• Pluripotency
• Developmental Biology
• +3 more

Professor Hans Schöler is a leading stem cell biologist and Director of the Max Planck Institute for Molecular Biomedicine in Münster, Germany. He holds simultaneous academic roles as Professor at the Medical Faculty of the University of Münster, Distinguished Professor at UNIST (Ulsan National Institute of Science and Technology) and Konkuk University in South Korea, as well as Adjunct Professorships at the University of Pennsylvania and Hannover Medical School. His research focuses on pluripotency mechanisms, stem cell reprogramming, and organoid modeling for regenerative medicine. Key affiliations include leadership roles in the ISSCR (International Society for Stem Cell Research) Board since 2015, and active participation in the Cells-in-Motion (CiM) Cluster of Excellence. Dr. Schöler’s work bridges basic research and clinical translation, emphasizing ethical communication of stem cell research to the public and policymakers. Research interests span molecular regulation of pluripotency (Oct4/Sox2 networks), organoid-based disease modeling, and epigenetic reprogramming strategies. Recent work explores applications in neurodegenerative diseases (e.g., Parkinson’s, frontotemporal dementia) and liver fibrosis through organoid systems. His contributions have advanced methodologies for induced pluripotent stem cell (iPSC) generation, somatic cell reprogramming, and high-throughput organoid screening platforms integrated with AI analysis. He remains a vocal advocate for responsible science communication and public education about stem cell technologies.