Joel Weadge is an Associate Professor in the Biology Department at Wilfrid Laurier University , Waterloo, Ontario. His research focuses on bacterial biofilms, glycobiology, and protein structure-function relationships. Contact: jweadge@wlu.ca , Office: BA425 (Bricker Academic). Education: PhD in Microbiology (University of Guelph, 2006) BSc (Hons) in Microbiology (University of Guelph, 2000) Research Interests center on bacterial biofilms as virulence factors in pathogens like E. coli and Salmonella . Key areas include: Structural and functional characterization of biofilm proteins (cellulose, curli fimbriae) Enzymology of carbohydrate modifications (acetylation, phosphoethanolamine transfer) Developing therapeutics targeting biofilm synthesis Biopolymer applications for medical/industrial use Publications highlight studies on Pseudomonas and Salmonella biofilm mechanisms, glycosyltransferases, and carbohydrate-active enzymes, with methodologies spanning X-ray crystallography to high-throughput biofilm profiling. Labs and Teams: The Weadge Lab investigates biofilm roles in food/water security and oral health, utilizing enzymology, mass spectrometry, and structural biology. Current members include graduate students, technicians, and research assistants.
Raphael Franzini serves as Associate Professor of Medicinal Chemistry at the University of Utah, actively contributing to the Biological Chemistry PhD Program. His research pioneers innovative chemical approaches for therapeutic development, with dual focus on DNA-encoded library technologies and bioorthogonal drug delivery systems. His educational foundation includes an M.S. from the Swiss Federal Institute of Technology (Lausanne) and a Ph.D. from Stanford University. This training underpins his group's multidisciplinary methodology combining organic synthesis, bioconjugation, computational modeling, and advanced imaging techniques. Dr. Franzini's research program centers on two transformative areas: First, advancing DNA-encoded library screening through computational integration to identify leads for challenging targets like Tankyrase and Sirtuin 6, with recent work addressing false negatives in machine learning prediction. Second, developing novel bioorthogonal release chemistry using isonitrile-tetrazine reactions for spatiotemporally controlled drug activation, validated in zebrafish models. His group emphasizes both technological innovation and therapeutic translation, with chemistry designed to minimize off-target effects in solid tumors. Analysis of his 15 most recent publications reveals escalating integration of computational methods with experimental library screening, alongside refinement of bioorthogonal release kinetics. The work spans chemical biology, medicinal chemistry, and pharmaceutical sciences, with growing emphasis on machine learning for library data interpretation and in vivo validation of drug-release systems. Dr. Franzini maintains an active research laboratory that provides comprehensive training in cutting-edge drug discovery methodologies. His group culture prioritizes both scientific innovation and researcher development, with projects spanning from fundamental reaction kinetics to therapeutic applications. The lab's infrastructure supports organic synthesis, molecular imaging, and computational analysis for advancing precision therapeutics.
Mike Kirby is a Professor at the Kahlert School of Computing, University of Utah. He also holds adjunct professorships in the Department of Bioengineering and the Department of Mathematics. His current roles include leadership in scientific computing and informatics initiatives, including former directorships of the Utah Informatics Initiative (2019-2023) and the Multi-Scale Multidisciplinary Modeling of Electronic Materials (MSME) Collaborative Research Alliance (2016-2022). He has extensive experience in strategic research initiatives, including serving as Assistant Vice President for Research (2024-2025). Education: Dr. Kirby earned a PhD in Applied Mathematics (2002) and MS in Computer Science (2001) from Brown University, and a BS in Applied Mathematics and Computer Science from Florida State University (1997). Research Interests: Focus on large-scale scientific computing, physics-informed machine learning, computational science and engineering, high-order numerical methods, and visualization. His work bridges applied mathematics and computer science to address real-world engineering challenges. Publications: Over 150 peer-reviewed articles, including high-impact contributions in journals like Journal of Computational Physics and SIAM Journal on Scientific Computing . Recent work emphasizes machine learning for differential equations, topology optimization under uncertainty, and multi-fidelity modeling. Awards: Recognized for leadership in computational science and informatics, including contributions to University of Utah’s Clery Compliance Program. Advising & Grants: Supervised over 50 graduate students and postdocs. Secured funding from NSF, DOE, and industry partnerships, totaling millions in research grants. Active in interdisciplinary collaborations across engineering, materials science, and medicine. Labs/Teams: Scientific Computing and Imaging (SCI) Institute, Utah Informatics Initiative, and the Center for Multiscale Modeling of Electronic Materials (MSME).
Dana Pe'er is a Professor and Chair of the Computational and Systems Biology Program at the Sloan Kettering Institute (SKI) of Memorial Sloan Kettering Cancer Center. She is also an Investigator of the Howard Hughes Medical Institute and holds the Alan and Sandra Gerry Endowed Chair. Dr. Pe'er leads an interdisciplinary research group that combines advanced genomics approaches with machine learning to address fundamental questions in biomedical science, with particular focus on cancer biology, developmental biology, and immunology. Dr. Pe'er earned her PhD from Hebrew University in Jerusalem, Israel. Her academic journey includes a postdoctoral fellowship with George Church at Harvard Medical School. Before joining Memorial Sloan Kettering Cancer Center in 2016, she held faculty positions at Columbia University. Dr. Pe'er's research focuses on understanding cellular plasticity, the consequences of intra-tumor heterogeneity, cancer evolution and metastasis, and the mechanisms by which regulatory circuits go awry in disease. Her lab combines single-cell and spatial profiling technologies with machine learning approaches to investigate gene regulation, cellular plasticity, and cell-cell communication in the contexts of cancer, immunity, and development. They are particularly interested in how organisms develop from a single cell to generate diverse cell types, how epigenetic control rewires during development, and how cells communicate to execute multicellular responses. Analysis of Dr. Pe'er's recent publications reveals a strong focus on developing computational methods for single-cell and spatial genomics data analysis. Her work spans cancer types including pancreatic, prostate, colorectal, and breast cancer, with emphasis on tumor heterogeneity, metastasis mechanisms, and cellular plasticity. A significant portion of her research involves creating novel algorithms and tools like CellRank, REUNION, and SEACells that enable researchers to extract meaningful biological insights from complex genomic datasets. 2023 Class of 2023 Inductee - American Academy of Cancer Research (AACR) Academy 2023 Innovator Award - International Society for Computational Biology (ISCB) 2021 Fellow - International Society for Computational Biology (ISCB) Howard Hughes Medical Institute Investigator (2021) 2019 Ernst W. Bertner Memorial Award - University of Texas MD Anderson Cancer Center 2016 Lenfest Distinguished Faculty Award - Columbia University 2014 Director's Pioneer Award - National Institutes of Health 2014 Overton Prize - International Society for Computational Biology (ISCB) Dr. Pe'er is known for her dedicated mentorship approach, describing herself as "a mama bear" who cares deeply about her trainees while expecting independence, innovation, and hard work. She mentors numerous PhD students and postdocs in her lab. Her HHMI Investigator award provides approximately $9 million over seven years, enabling ambitious research directions. She also collaborates extensively with the Single-cell Analytics and Innovation Lab (SAIL) at MSK to generate new data from emerging technologies, working closely with wet-lab collaborators at MSK and beyond to apply computational methods to cutting-edge datasets across multiple disease areas. The Pe'er Lab is an interdisciplinary group of computational biologists with diverse backgrounds ranging from pure mathematics to clinical medicine. They work closely with wet-lab collaborators to apply their computational methods to cutting-edge datasets across cancer, immunology, and developmental biology. The lab is described as open, supportive, collaborative, and fun, with access to world-class facilities at the Sloan Kettering Institute. Dr. Pe'er's work continues to push the boundaries of computational biology and cancer research, with the ultimate goal of developing more effective, personalized therapies for cancer patients.
Dr. Igor V. Pivkin is a Full Professor at the Institute of Computing within the Faculty of Informatics at the Università della Svizzera italiana (USI) in Lugano, Switzerland. His academic journey includes degrees from Novosibirsk State University (B.Sc./M.Sc. Mathematics), Brown University (M.Sc. Computer Science and Ph.D. Applied Mathematics), and postdoctoral research at MIT's Department of Materials Science and Engineering. His research focuses on multiscale/multiphysics modeling , numerical methods , and large-scale simulations of biological and physical systems. Key areas include biophysics, cellular/molecular biomechanics, stochastic modeling, and coarse-grained molecular simulations. He leverages high-performance computing (HPC) and particle-based methods to address complex biological phenomena. His work spans diverse applications, from understanding cellular mechanosensitivity and biofilm engineering to modeling cancer cell behavior and red blood cell dynamics in the spleen. His contributions bridge computational science, biotechnology, and biomedical research. He has published extensively in top-tier journals, with recent work advancing automated biofilm analysis, deep learning for microbial classification, and systems biology approaches to metal bioleaching. His lab collaborates on interdisciplinary projects, emphasizing computational innovation for real-world biological challenges.
Konstantinos Kalogeropoulos is an Assistant Professor at the Department of Biotechnology and Biomedicine, Technical University of Denmark (DTU), leading research at the Cell Diversity Lab. His work bridges proteomics, computational biology, and snake venom research. Current projects: "The Proteomic Landscape during Influenza Infection" (2022-2025) Supervisor for PhD projects on protease network rewiring in psoriasis and wound exudate degradomics Research interests include: Proteomic analysis of inflammatory diseases Snake venom toxin structure prediction Extracellular matrix biomechanics De novo peptide sequencing algorithms Computational modeling of protease networks Recent article trends demonstrate his work in • Database-free proteomics (InstaNovo/InstaNexus) • Snake venom pathophysiology (V-ToCs clustering) • Inflammatory disease biomarkers (psoriasis, impaired healing) • Extracellular matrix mechanics (fibronectin tension, gut inflammation) Advising: Supervises PhD students Polhaus, C. J. M. and Haack, A. M., focusing on protease networks and wound healing.
Jethro Johnson is an Innovation Track Principal Investigator at the Kennedy Institute of Rheumatology and Deputy Director of the Oxford Centre for Microbiome Studies (OCMS) at the University of Oxford. His work integrates computational genomics and microbiome research to explore host-microbiome interactions in health and disease. PhD in Nutritional Ecology (University of Auckland, 2012) MRC Career Development Fellowship Former postdoctoral researcher at Jackson Laboratory for Genomic Medicine Research focuses on: Mechanistic understanding of gut microbiome impacts on metabolic diseases Multi-omic data integration for host-microbiome studies Computational approaches to microbiome analysis Methodological developments in 16S rRNA gene profiling Publications emphasize microbiome-disease associations, methodological innovations, and computational genomics applications across human and mouse models. Key themes include metabolic dysfunction, immune interactions, and microbial diversity analysis. Scientific recognition includes: MRC Career Development Fellowship in Computational Genomics As OCMS Deputy Director, he contributes to advancing microbiome research infrastructure and collaborative projects while leading his own computational genomics group at the Kennedy Institute.
Anders Krogh is a Professor at the Department of Computer Science, University of Copenhagen, and also holds a position at the Department of Public Health in the Section for Health Data Science and AI. He serves as the head of the Center for Health Data Science (HeaDS) in the Faculty of Health and Medical Sciences. Previously, he was affiliated with the Department of Biology at the University of Copenhagen until 2020. Dr. Krogh earned his PhD in theoretical physics but transitioned into machine learning and bioinformatics during his doctoral studies. His research spans both theoretical foundations and practical applications in these fields. He is particularly renowned for his pioneering work on hidden Markov models for biological sequences, which has had significant impact in computational biology. In recent years, Krogh's research has focused on deep generative models applied to gene expression data and other biomedical applications. His work bridges computer science with healthcare, developing AI-driven approaches for precision medicine, cancer diagnostics, and analysis of complex biological systems. His current research integrates machine learning with quantum computing applications in biomolecular modeling. Analysis of his recent publications reveals a strong trend toward applying artificial intelligence to healthcare challenges, particularly in rare diseases, cancer diagnostics, and personalized medicine. His work increasingly incorporates federated learning approaches to address privacy concerns while enabling collaborative research across institutions. There's also a growing emphasis on quantum computing applications in biomolecular modeling and drug discovery. As head of the Center for Health Data Science, Krogh leads interdisciplinary research efforts that bring together computer scientists, medical researchers, and clinicians. His team develops novel computational frameworks like MOSAIC for multimodal analysis of rare cancers and multiDGD for multi-omics data integration. These tools are designed to translate AI innovations into clinical practice while addressing the unique challenges of medical data.
Dr. Rong Fan is the Harold Hodgkinson Professor of Biomedical Engineering and Professor of Pathology at Yale University. His research focuses on developing and applying single-cell and spatial omics technologies to study immune systems, cancer, and aging. His lab has pioneered technologies like the IsoCode microchip for high-throughput protein profiling, and spatial multi-omics platforms (e.g., DBiT-seq, spatial-ATAC-seq) to analyze tissue complexity at cellular resolution. He co-founded IsoPlexis, Singleron Biotechnologies, and AtlasXomics to commercialize these innovations. Education: PhD in Chemistry from UC Berkeley (2006), B.S. in Applied Chemistry from University of Science and Technology of China (1999). Postdoctoral training at Caltech before joining Yale in 2010. Research interests include CAR-T cell therapy optimization, spatial epigenomics, and multi-omics integration. Key achievements include discovering biomarkers predictive of CAR-T efficacy and defining spatial genomic landscapes in cancer and neuroinflammation. Awards: NSF CAREER Award, Packard Fellowship, election to AIMBE, CASE, and NAI. Serves on advisory boards for Bio-Techne and Yale Ventures. Active in training future scientists via the Yale Biomedical Engineering and Yale School of Medicine programs.
Vitaly Kheyfets, PhD, serves as Associate Professor in the Department of Pediatrics-Critical Care Medicine at the University of Colorado Anschutz Medical Campus School of Medicine, where he directs research at the intersection of pediatric critical care and cardiopulmonary pathophysiology with emphasis on pulmonary arterial hypertension (PAH). His primary research focuses on right ventricular adaptation to pulmonary hypertension, utilizing machine learning-driven multi-omics analysis to identify disease biomarkers and molecular networks. He pioneers computational fluid dynamics approaches for hemodynamic modeling in congenital heart conditions like Glenn physiology, while also investigating sleep oscillatory patterns as neurodegenerative biomarkers. His methodology integrates proteomics, spatial transcriptomics, and pressure waveform analysis to dissect vascular remodeling mechanisms. Publication trends reveal a strong emphasis on translating computational models into clinical applications for PAH prognostication, with recent work developing AI-cooperative diagnostic platforms and characterizing microvascular changes in the right ventricle. Cross-disciplinary collaborations span proteomics, imaging, and sleep neuroscience, demonstrating consistent innovation in both pulmonary hypertension and neurodegenerative disease biomarker discovery.
Dr. Ian Wilson is a researcher at Newcastle University with a focus on medical genetics, nephrology, and genomic analysis. His work spans genetic determinants of kidney diseases, mitochondrial disorders, and biomarker development. Notable contributions include studies on uromodulin genetics in African populations, copy-number variations in rare diseases, and kidney ciliopathies. He has collaborated extensively on projects involving genome sequencing, mitochondrial replacement therapy, and muscular dystrophy biomarkers. Wilson's research integrates computational tools like machine learning for predictive modeling in urolithiasis and employs advanced imaging techniques for disease progression monitoring. Key areas: Genetic epidemiology, renal genomics, mitochondrial DNA analysis Focus on translational applications: Biomarker development for kidney stones and muscular dystrophies Interdisciplinary collaborations in ophthalmology and orthopedics His publications reflect a commitment to advancing diagnostic accuracy and understanding complex genetic disorders through multi-omics approaches.
Bertram Müller-Myhsok is a Research Professor and Research Group Leader at the Max Planck Institute of Psychiatry in Munich, Germany. His research focuses on statistical genetics and transcriptomic data analysis in psychiatric disorders, particularly major depression, PTSD, schizophrenia, and their treatment responses. He integrates machine learning with genetic and clinical data to develop predictive models and stratified treatment approaches. Professional activities include leadership roles in the International Max Planck Research School for Translational Psychiatry and collaborations with institutions like the Institut du Cerveau (Paris) and Bernhard Nocht Institute (Hamburg). His work spans genetic epidemiology, psychiatric genomics, and precision medicine, with over 400 publications in high-impact journals. Key research areas include identifying genetic risk factors for mental disorders, developing polygenic scores, and leveraging omics data to uncover disease mechanisms. He leads projects like Psych-STRATA, a Horizon Europe-funded initiative advancing personalized psychiatry through pharmacogenomics.
Yang Luo is a Kennedy Trust Senior Research Fellow in Data Science at the University of Oxford's Kennedy Institute of Rheumatology. His research bridges statistical genomics and computational immunology to unravel genetic contributions to immune-mediated traits, with a focus on the major histocompatibility complex (MHC) region. His work leverages large biobank datasets (UK Biobank, Biobank Japan), gene expression resources (GTEx), and proteomic data to decode molecular mechanisms linking genetic variation to disease risk. Specific interests include tuberculosis genetics, multi-ancestry polygenic risk scores, and single-cell eQTL modeling. Recent publications highlight expertise in HLA association studies, evolutionary immunogenetics, and disease-specific cell state dynamics. Key contributions include constructing a global HLA haplotype panel and developing novel statistical methods for admixed population genetics. Scientific Awards: Kennedy Trust Senior Research Fellow in Data Science His lab integrates computational and experimental approaches to translate genetic findings into clinical applications for immune disorders.
Ying Ge is a Professor at the University of Wisconsin–Madison, jointly appointed in the Department of Cell and Regenerative Biology and the Department of Chemistry. Her research integrates chemistry, biology, and medicine, focusing on advanced mass spectrometry-based proteomic and metabolomic technologies to address cardiovascular diseases. Education: B.S., Peking University (1997) Ph.D., Cornell University (2002) Ying Ge's work centers on developing ultra high-resolution mass spectrometry platforms for top-down proteomics and metabolomics, applied to systems biology studies of heart failure and regenerative medicine. Key projects include myofilament protein modification mapping, stem cell therapy evaluation, and biomarker discovery for cardiac conditions. The 15 most recent articles highlight her lab's methodological innovations (e.g., photocleavable surfactants, native mass spectrometry) and biological discoveries in AMPK structural heterogeneity, RBM20-mediated cardiotoxicity, and sarcomere-metabolism cross-talk during regeneration. These publications span proteomics, metabolomics, structural biology, and clinical applications.
Yuyin Zhou is an Assistant Professor in the Department of Computer Science and Engineering at the University of California, Santa Cruz (UCSC), within the Baskin School of Engineering. She previously held a postdoctoral fellowship at Stanford University, collaborating with Prof. Lei Xing and Prof. Matthew Lungren. She earned her Ph.D. in Computer Science from Johns Hopkins University under the supervision of Bloomberg Distinguished Professor Alan Yuille. Her research is centered on advancing biomedical artificial intelligence to match medical experts in decision-making. Key focuses include developing medical multimodal models, building fair and trustworthy real-time learning systems for clinicians and patients, enabling one-shot/few-shot adaptation of foundation models to diverse medical tasks, and generating synthetic data aligned with clinical knowledge. Dr. Zhou’s recent publications span top-tier venues such as Nature Medicine , Medical Image Analysis , ICLR, CVPR, NeurIPS, MICCAI, and ECCV, reflecting a strong trend in foundation models for medical imaging, trustworthy AI, and efficient deployment. Her work bridges computer vision, deep learning, and clinical applications, with notable projects including TransUNet, BioMedGPT, and MicroSegNet. She has been recognized with the Google Research Scholar Award and the Hellman Fellowship . Dr. Zhou actively contributes to the academic community as an Area Chair for CVPR, ICLR, MICCAI, and CHIL. She organizes workshops and tutorials, including the CVPR 2024 Workshop on Foundation Models for Medical Vision and MICCAI 2024’s FOMMIA tutorial. Google Research Scholar Award Hellman Fellowship Dr. Zhou is actively recruiting self-motivated PhD students and interns to work on machine learning, computer vision, and AI for healthcare. She leads a dynamic research group focused on pushing foundation models into real-world clinical settings. Her team has launched public datasets, such as a micro-ultrasound dataset for prostate segmentation, and open-sourced tools to foster community collaboration.
