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Dr. Maurice Zandvliet is an Associate Professor at the Department of Clinical Sciences , Faculty of Veterinary Medicine, Utrecht University. His work bridges comparative oncology , radiation therapy , and internal medicine for companion animals. Education: Veterinary Medicine (Utrecht, 2000), PhD (2014) Specializations: European Veterinary Specialist in Small Animal Internal Medicine (2007), Medical Oncology (2015) His research focuses on hematopoietic tumors in dogs and cats, particularly drug resistance mechanisms (e.g., ABC transporters in lymphoma) and radiotherapy optimization for nasal and brain tumors. He has developed protocols for chemotherapy , radiation , and hyperthermia combinations in veterinary cancer treatment. Recent work includes organoid-based drug screening for personalized oncology and liposomal radiosensitizer delivery . He contributes to translational research , linking canine melanoma studies to human mucosal melanoma treatments. Notable projects involve doxorubicin cardiotoxicity risk factors and flow cytometry applications in tumor diagnostics. He leads the Misdorp Center for Veterinary Radiation Oncology and participates in European specialty training programs.

• Veterinary Oncology
• Radiation Therapy
• Companion Animal Internal Medicine
• +5 more

Den Toonder is a Professor in the Department of Mechanical Engineering at Eindhoven University of Technology (TU/e), leading the Group Den Toonder focused on microfluidics and biomedical device development. His research spans microactuators, organ-on-chip systems, and applications such as cancer diagnostics and glaucoma implants. He oversees a team of 37 researchers and has supervised over 65 student theses, emphasizing collaborative projects with biomedical and clinical groups. His work contributes to UN Sustainable Development Goals through innovations in healthcare and sustainable technologies. Research interests include microfluidic actuation systems, magnetic bead actuation, and biomimetic designs. Notable projects include developing a minimally invasive glaucoma implant and organ-on-chip models for cancer studies. His lab integrates fabrication techniques like femtosecond laser machining and employs advanced sensors for real-time diagnostics. Publications highlight advancements in sweat-based health monitoring, microfluidic mixing via artificial cilia, and tissue barrier sensor chips. His team’s work bridges engineering and medicine, with applications in non-invasive diagnostics and regenerative medicine.

• Microfluidics
• Biomedical Engineering
• Microactuators
• +3 more

Guillaume P.R. Lajoinie serves as Associate Professor across multiple institutes at the University of Twente: Digital Society Institute, MESA+ Institute, Physics of Fluids research group, and TechMed Centre. His interdisciplinary work bridges physics, engineering, and medical applications with emphasis on ultrasound technologies and microbubble dynamics for therapeutic and diagnostic purposes. His research profile is dominated by Ultrasound Physics (100% fingerprint match) and Bubbles Physics (85%), with significant contributions to Contrast Physics (42%), Acoustics Physics (37%), and Droplet Physics (32%). Current investigations focus on microbubble stability for drug delivery systems, immunogenic cell death mechanisms in cancer therapy, and computational simulation of ultrasound phenomena through projects like the PROTEUS simulator. His work consistently integrates fluid dynamics with medical imaging applications. 2025 publications reveal accelerating output in ultrasound simulation, microbubble engineering, and cardiovascular imaging techniques. Key trends include computational modeling of contrast agents, attenuation correction algorithms for plaque imaging, and physical cancer therapy-immunotherapy synergies. His research maintains strong clinical translation focus through TechMed Centre collaborations. Lajoinie has supervised 5 graduate students and maintains active research leadership through the Physics of Fluids group. His work demonstrates consistent growth in publication output since 2012, with 2025 showing peak productivity (9 outputs). He leverages cross-institute resources at University of Twente for experimental and computational approaches to biomedical ultrasound problems. Laboratory work centers on the Physics of Fluids experimental facilities with extensions to TechMed Centre's medical technology platforms. Current team efforts focus on microbubble production systems, ultrasound simulation frameworks, and tumor-on-a-chip models for therapy testing, reflecting his fingerprint's emphasis on Combination Therapy Medicine and In Vitro systems.

• Ultrasound Physics
• Bubbles Physics
• Contrast Physics
• +5 more

Hadi Mirgolbabaee is a Medical Imaging Researcher at the TechMed Centre, University of Twente, specializing in vascular hemodynamics and interventional radiology procedures. He recently completed his PhD in December 2024 with research focused on endovascular aortic repair and flow quantification. His research interests center on mathematical modeling of vascular systems , in vitro testing of medical devices , and optimization of interventional radiology procedures . Dr. Mirgolbabaee has developed innovative approaches for microcatheter behavior analysis during radioembolization procedures and created advanced vascular phantoms for hemodynamic studies. His work bridges physics, mathematics, and clinical medicine to improve understanding of complex vascular dynamics. His publication record shows consistent research activity from 2015-2025, with recent focus on transarterial radioembolization techniques, abdominal aortic aneurysm modeling, and advanced imaging phantom development. The publications demonstrate strong interdisciplinary collaboration across medical physics, engineering, and clinical specialties. His research has been recognized with citations in Scopus, contributing to the fields of medical physics and interventional radiology. While specific awards aren't listed in the provided information, his h-index of 12 with 123 citations indicates significant scholarly impact in his field. Dr. Mirgolbabaee actively collaborates with researchers across multiple institutions, particularly in the Netherlands, with recent work involving colleagues from medical physics, vascular surgery, and interventional radiology departments. His research has practical applications in improving cancer treatment delivery systems and vascular intervention outcomes.

• Medical Imaging
• Biomedical Engineering
• Hemodynamics
• +6 more

Albert van den Berg is a Full Professor at the University of Twente, affiliated with the MESA+ Institute and the Biomedical and Environmental Sensorsystems department. His research focuses on microfluidics, organ-on-chip systems, nanotechnology, and biomedical sensors, contributing to UN Sustainable Development Goals in Health, Energy, and Environmental Sustainability. Notable projects include blood vessel-on-chip models for disease studies and force-tracking tools for cardiac tissue analysis. Education: Formal academic qualifications not explicitly listed, but his titles imply doctoral (prof.dr.ir.) and engineering qualifications. Research Interests: Microfluidic devices for biomedical applications, organ-on-chip platforms for disease modeling (e.g., cardiovascular systems, cancer), nanotechnology for catalysis and sensing, and integrated sensor systems for environmental monitoring. His work bridges engineering and life sciences, emphasizing translational research. Collaborations: Active in multidisciplinary networks, collaborating globally on projects involving 3D tissue modeling, nanomaterials, and microreactor technologies. Key partners include Maastricht University and industry collaborators in biotechnology. Grants & Labs: Leads research groups in the MESA+ Institute and Biomedical Sensors lab. Involved in EU and national grants supporting organ-on-chip and nanotechnology initiatives. Labs/Teams: Directs the Biomedical and Environmental Sensorsystems lab, specializing in microfluidic systems and organ-on-chip development. Collaborates with teams in materials science and clinical medicine.

• Biomedical Engineering
• Nanotechnology
• Microfluidics
• +5 more

Dr. Hans Bosch is an Associate Professor in the Department of Cardiology at Erasmus MC. His research focuses on advancing medical imaging technologies, particularly in ultrasound-based systems and biomedical engineering applications. He has contributed to innovations in high-resolution 3D ultrasound probes, subharmonic imaging for blood pressure measurement, and microbubble stability in contrast agents. His work integrates engineering principles with clinical cardiology, emphasizing cross-disciplinary collaboration. Recent studies include validation of echo-particle velocimetry against MRI and development of CMUT (capacitive micromachined ultrasonic transducer) array technologies for real-time imaging. Bosch’s research aims to enhance diagnostic accuracy and non-invasive measurement techniques in cardiovascular medicine. Key collaborations involve teams from solid-state circuits and biomedical instrumentation. His publications highlight advancements in transducer design, signal processing, and contrast-enhanced ultrasound applications.

• Medical Imaging Technology
• Biomedical Engineering
• Cardiac Imaging
• +3 more

Sander Spiekhout is a Researcher in the Cardiology department at Erasmus MC , focusing on biomedical engineering and ultrasound contrast imaging. His work involves analyzing microbubble dynamics and their applications in cardiovascular diagnostics. Key Collaborations : Y. Wang, T. Segers, K. Kooiman, M. Versluis Research Areas : Ambient Pressure Sensitivity, Microbubble Stability, Ultrasound-Driven Dynamics Research Trends : Recent publications highlight advancements in subharmonic ultrasound imaging for blood pressure monitoring, microbubble shell characterization, and the impact of surfactants on contrast agent stability. Collaborative work focuses on dual-frequency imaging methods and viscoelastic shell analysis.

• Biomedical Engineering
• Acoustics
• Medical Imaging
• +3 more

Peiran Chen is a University Researcher at Eindhoven University of Technology (TU/e), affiliated with the Faculty of Electrical Engineering's Signal Processing Systems group. He holds dual appointments at the Center for Care & Cure Technology Eindhoven and the Eindhoven MedTech Innovation Center (e/MTIC), focusing on translational medical ultrasound research. His research centers on contrast-enhanced ultrasound (CEUS) innovation for clinical diagnostics, specializing in microbubble-based microvasculature characterization. Key applications include renal cell carcinoma detection through dispersion imaging, prostate cancer biopsy prediction using multiparametric ultrasound, and placental vasculature assessment in obstetrics. His methodology integrates advanced signal processing with hemodynamic modeling to extract quantitative biomarkers from ultrasound data. Recent publications (2023-2025) reveal a strategic focus on oncological applications, particularly kidney and prostate cancers, while expanding into cardiovascular and obstetric domains. The work emphasizes translating microbubble physics into clinical decision tools, with strong emphasis on quantitative imaging biomarkers and super-resolution techniques. Chen co-developed an integrated cancer localization platform (2018-2022) for ultrasound microvasculature imaging and contributes to EU-level biomedical consortia. His research demonstrates consistent industry-clinical collaboration, evidenced by media coverage of microbubble-based tumor vasculature studies in 2022. As a core e/MTIC member, he operates within TU/e's ecosystem bridging engineering and clinical medicine, utilizing facilities like the Center for Care & Cure Technology for preclinical validation and clinical translation of ultrasound innovations.

• Medical Ultrasound Imaging
• Biomedical Signal Processing
• Cancer Diagnostics
• +3 more

Hessel Wijkstra is a Full Professor in the Signal Processing Systems Group at Eindhoven University of Technology and a principal investigator in the Department of Urology at Amsterdam University Medical Center (AMC). He bridges engineering and clinical medicine, focusing on advanced medical imaging technologies. Academic Background : MSc and PhD in Electrical Engineering from Twente University. Research Focus : Clinical validation of imaging technologies, particularly contrast-enhanced ultrasound for prostate cancer and renal cell carcinoma . Key Contributions : Development of dispersion imaging techniques, super-resolution ultrasound , and machine learning for cancer diagnostics. Collaborations : Long-standing partnership with Massimo Mischi since 2010, integrating engineering and urology. Scientific Awards : EFSUMB Young Investigator Award (2019) Media Engagement : Frequent expert commentary on nanobubbles , AI in imaging , and ultrasound advancements (2018-2023).

• Medical Imaging
• Contrast-Enhanced Ultrasound
• Prostate Cancer
• +5 more

Martin D. Verweij is an Associate Professor at the Laboratory of Acoustical Wavefield Imaging within the Faculty of Applied Sciences at Delft University of Technology. Since 2015, he maintains a part-time position at the Biomedical Engineering group of Erasmus Medical Centre in Rotterdam, bridging academic research with clinical applications. Dr. Verweij earned his M.Sc. (cum laude) and Ph.D. in electrical engineering from Delft University of Technology in 1988 and 1992. His career includes a Research Fellowship with the Royal Netherlands Academy of Arts and Sciences (1993-1997) and visiting scientist positions at Schlumberger Cambridge Research. He joined Delft University as Assistant Professor in 1998, becoming Associate Professor later that year, initially in Electromagnetic Research before moving to Acoustical Wavefield Imaging in 2011. His research focuses on medical ultrasound technology, specializing in transducer design, beamforming algorithms, and theoretical modeling of ultrasound wavefields. He is renowned as the originator of the Iterative Nonlinear Contrast Source (INCS) method for computing nonlinear ultrasound fields. His work spans fundamental acoustical theory and practical clinical applications, particularly in cardiac imaging and contrast-enhanced ultrasound. Recent publications reveal his leadership in developing advanced ultrasound technologies including high-frame-rate 3D imaging systems, innovative transducer calibration methods, and microbubble contrast agent research. His scholarly output demonstrates consistent integration of electrical engineering principles with medical imaging applications, enhancing diagnostic capabilities across multiple medical specialties. As a research leader for the Dutch Technology Foundation (NWO/TTW), Dr. Verweij oversees projects involving transducer design and imaging technologies. His work has produced 267 research outputs and he has supervised 14 graduate students according to his Scopus profile. His laboratory focuses on developing next-generation ultrasound technologies with emphasis on 3D imaging systems, transducer innovation, and novel beamforming approaches. Current projects include high-volume rate ultrasound probes, specialized transceiver ASICs for medical applications, and acoustic streaming-based calibration techniques that improve imaging precision.

• Medical Acoustical Imaging
• Cardiac Ultrasound
• Transducer Design
• +3 more

Tim Joseph Segers holds the position of Associate Professor in three departments: Biomedical and Environmental Sensorsystems, MESA+ Institute, and TechMed Centre. His academic roles span multiple interdisciplinary fields within biomedical engineering and materials science. His research focuses on advancing ultrasound technology, microbubble dynamics, and biomedical imaging applications. Key interests include the behavior of microbubbles under varying pressures, development of contrast agents for medical imaging, and the application of acoustic principles in inkjet printing and fluid dynamics. His work bridges fundamental physics with clinical and engineering innovations. Dr. Segers has supervised seven students, contributing to their academic and research development. While no specific grants are detailed in this profile, his research has been published in high-impact journals, reflecting ongoing support for his projects. He is affiliated with the TechMed Centre and MESA+ Institute, which provide collaborative environments for his interdisciplinary research endeavors.

• Ultrasound Technology
• Biomedical Engineering
• Acoustic Sensors
• +4 more

Andreas Pollet is a University Lecturer in the Computational and Experimental Mechanics (CEM) research group and a researcher in the Microsystems group at Eindhoven University of Technology (TU/e). He combines teaching and research, focusing on microfluidics, organ-on-a-chip technology, mechanobiology, and regenerative medicine. His work emphasizes recreating functional human tissues in microfluidic devices for applications like drug development and disease modeling. Academic Background Bachelor and PhD in Biomedical Engineering (TU/e) Postdoctoral research at Sanquin Research (Bone Marrow-on-Chip project) Research Pollet’s research bridges engineering and biology, with contributions to hydrogel-based tubular organ-on-a-chip models, ultrasound imaging systems for vascular validation, and microbubble dynamics in medical diagnostics. His work aims to improve physiological accuracy in in vitro models and advance biomedical technologies. Key Projects LOCATE project (microvasculature modeling) Bone marrow-on-chip for platelet formation studies Labs & Affiliations Eindhoven MedTech Innovation Center Group Den Toonder (TU/e)

• Microfluidics
• Organ-on-a-Chip Technology
• Mechanobiology
• +2 more

Xuehua Zhang is a Full Professor at the MESA+ Institute, specializing in the Physics of Fluids. Her research examines interfacial phenomena, microdroplet physics, and bubble dynamics with applications in energy and environmental technologies. Her work focuses on surface chemistry, fluid mechanics, and colloidal systems, with recent investigations into hydrogen production using microdroplets and advanced water treatment methods combining microbubbles with cold plasma technology. Recent publications demonstrate innovation in sustainable energy storage and water treatment technologies, with particular focus on microdroplet reactors for hydrogen production and plasma-based water purification systems.

• Surface Chemistry
• Microdroplet Physics
• Bubble Dynamics
• +2 more

Frits Mastik is a Researcher in the Department of Neurosciences at Erasmus University Medical Center (Erasmus MC), specializing in advanced ultrasound imaging technologies for clinical applications. His work bridges engineering and medical diagnostics with a focus on real-time brain and cardiovascular monitoring. His research spans Medical Ultrasound, Intravascular Ultrasound, Functional Ultrasound (fUS), and Neuroimaging, with significant contributions to Ultrasound Transducer Development and Motion Compensation Algorithms. Current projects emphasize Elastography and Ultrasound Contrast Agents for improved tissue characterization during surgical procedures. Recent publications reveal a dominant trend in functional ultrasound for intraoperative neuroimaging, particularly integrating fUS with fMRI and electrocorticography during awake brain tumor resections. His team pioneers mobile brain imaging systems using acoustically optimized skull implants, enabling monitoring in freely moving subjects while exploring contrast-agent dynamics through ultra-high-speed camera systems. Collaborations span neurosurgeons, biomedical engineers, and neuroscientists across Erasmus MC, with co-authorship on translational projects involving skull implant technology and motion artifact correction for surgical applications.

• Medical Ultrasound
• Intravascular Ultrasound
• Functional Ultrasound (fUS)
• +5 more

Klazina Kooiman is an Associate Professor in the Department of Cardiology at Erasmus MC, where she leads research in ultrasound-mediated therapies, microbubble technology, and targeted drug delivery. Her work bridges biomedical engineering and clinical cardiology, focusing on innovative methods to enhance therapeutic efficacy using acoustic agents. Her research interests center on microbubble dynamics , sonoporation , and contrast-enhanced ultrasound . She investigates how engineered microbubbles can be used to locally deliver drugs to endothelial tissues and tumors, leveraging ultrasound to trigger controlled permeabilization of cell membranes. Her lab employs advanced techniques such as confocal microscopy and acoustic characterization to study microbubble behavior under physiological conditions. The recent publications highlight a strong focus on monodisperse microbubbles , phospholipid coatings , and ultrasound-responsive drug carriers . These studies span from fundamental physics of bubble oscillations to translational applications in cardiovascular disease and oncology, indicating a cohesive research trajectory aimed at clinical translation of acoustic therapeutics. Kooiman has supervised multiple research projects, as indicated by her supervised work record. Though specific awards and grants are not listed, her consistent high-impact publications in journals like ACS Applied Materials and Interfaces and Journal of Controlled Release reflect recognition in her field. She collaborates extensively with experts in ultrasound physics, biomaterials, and cardiovascular biology. Her research group is actively involved in developing next-generation ultrasound contrast agents and therapeutic microbubbles. The team explores both soft- and hard-shelled microbubble systems, aiming to optimize stability, targeting, and bioeffects for safe clinical application.

• Ultrasound Imaging
• Microbubble Technology
• Targeted Drug Delivery
• +7 more