Margherita CantornaView profile
Professor
Dr. Margherita Cantorna is a Distinguished Professor of Molecular Immunology at the Department of Veterinary and Biomedical Sciences , Pennsylvania State University, and serves as Director of the Center for Molecular Immunology and Infectious Disease . She is affiliated with the Huck Institutes of the Life Sciences and leads a research program at the intersection of nutrition and immune function. Specializes in vitamin D and A's roles in immune regulation Focuses on autoimmune diseases like Inflammatory Bowel Disease (IBD) and Multiple Sclerosis (MS) Investigates gut microbiota interactions with dietary components Research Highlights: Her work demonstrates that developmental vitamin D deficiency exacerbates autoimmune disease susceptibility, with key findings in T cell differentiation , innate lymphoid cell function , and microbiome modulation . Recent publications span topics from vitamin D receptor signaling in hematopoiesis to nutritional strategies for infectious disease resistance . Developed novel VDR reporter mouse models Identified critical roles for vitamin D in IL-22 production and pathogen clearance Explored dietary fiber and mushroom impacts on gut immunity Lab Members: Includes graduate student Juhi Arora and collaborates with researchers across immunology, microbiology, and nutritional sciences. The Cantorna Lab employs cutting-edge transcriptomics and germ-free animal models to dissect diet-immune interactions.











