Find Academic Supervisors

Mohsin KhanView profile

Associate Professor

• Cardiac Repair Mechanisms
• Embryonic Signaling in Cardiac Regeneration
• Stem Cell Biology
• +3 more

Mohsin Khan, PhD, is an Associate Professor in the Department of Cardiovascular Sciences at the Lewis Katz School of Medicine, Temple University. He leads the Center for Metabolic Disease Research, focusing on cardiac regeneration and metabolic signaling. His work integrates stem cell biology, exosome-mediated communication, and epigenetic reprogramming to address cardiac repair deficits in aging/diabetes. Education: PhD in Molecular Biology, National Center of Excellence in Molecular Biology, Lahore (2008) MS in Zoology, Government College University, Lahore (2002) BS in Biological Sciences, Forman Christian College, Lahore (2000) Research Interests: Dr. Khan’s lab investigates neonatal cardiac repair mechanisms, embryonic microRNA signaling, and diabetes-induced cardiac dysfunction. Key projects include: Reactivation of embryonic factors to enhance adult heart repair Exosome-based therapies using stem cell-derived vesicles Metabolic regulation in cardiac progenitor cells Age-related epigenetic changes in heart repair capacity Publications: Over 80 peer-reviewed articles focus on miRNA regulation, exosome therapies, and metabolic-cardiac crosstalk. Recent work highlights LIN28A-driven regeneration and UCP2-mediated metabolic reprogramming. Honors: American Association for Cancer Research (AACR) American Association for the Advancement of Science (AAAS) Advising & Grants: Ongoing NIH-funded projects explore exosome-based cardiac repair and diabetes-cardiac axis modulation. Collaborations include Temple’s Institute of Regenerative Medicine and Engineering. Labs/Teams: Leads a multidisciplinary team at the Center for Metabolic Disease Research, collaborating with immunologists, bioengineers, and computational biologists to advance regenerative therapies.

• Cardiovascular Research
• Heart Failure
• Iron Deficiency Pathophysiology
• +3 more

Martijn Hoes is a Postdoctoral Researcher at the University of Groningen's Faculty of Medical Sciences , specializing in cardiovascular and molecular research. His work focuses on heart failure mechanisms, iron deficiency pathophysiology, and stem cell biology. He is affiliated with the Department of Biochemistry & Molecular Biology and holds an ORCID profile (0000-0002-0234-438X). Key research areas include: Cardiomyopathy genetics and clinical outcomes Iron deficiency effects on cardiac and skeletal muscle Desmosome-associated skin disorders Mitochondrial dysfunction in heart failure Notable contributions include studies on KLHL24 cardiomyopathy prognosis, iron deficiency's role in muscle atrophy, and engineered heart tissue biomechanics. He has secured grants including a Dekkers Beurs (2022) and UMCG funding (2021) for cardiovascular research. His work bridges molecular mechanisms with clinical applications, particularly in heart failure management. He collaborates widely, with recent projects involving Maastricht UMC+ and international teams. Lab activities focus on iPSC-derived cardiomyocyte modeling and multi-omics profiling.

Pinar ZorlutunaView profile

Professor

• Bioengineering
• Tissue Engineering
• Regenerative Medicine
• +12 more

Pinar Zorlutuna is the Roth-Gibson Professor of Bioengineering and Director of the Bioengineering Graduate Program at the University of Notre Dame, within the College of Engineering and the Department of Chemical and Biomolecular Engineering. She leads a dynamic research lab focused on bio-inspired systems for disease modeling and regenerative medicine. Research Interests: Her work centers on tissue engineering, genetic engineering, and micro/nanotechnology to create biomimetic models of human tissues. Key areas include aging, cancer (particularly breast), and cardiovascular disease. Her lab investigates cell-cell and cell-matrix interactions, with emphasis on extracellular vesicles, the cardiac microenvironment, and 3D bioprinting. The recent publications highlight a strong trend toward modeling age-related disease progression, especially in cardiac and breast tissue. Many studies explore how aging alters the extracellular matrix and vesicle cargo, influencing disease outcomes and drug responses. Another major theme is bio-inspired computing, with research on cardiac muscle cell-based networks for biocomputing and memory systems. Elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows National Academy of Sciences Kavli Fellow Roth-Gibson Professor of Bioengineering Member, NIH CSR Cellular and Molecular Technologies Study Section NSF CAREER Award NSF EFRI BEGIN Award Dr. Zorlutuna advises graduate students and leads major federally funded grants focused on aging heart models and cardiac biocomputing. Her lab, the Zorlutuna Lab, develops innovative tools such as 3D bioprinted tissue models, microfluidic devices, and bio-oscillatory networks. Future work includes advancing real-time diagnostic platforms, personalized tissue models, and implantable biocomputational systems.

Caroline BurnsView profile

Academic

• Cardiovascular Development
• Heart Regeneration
• Zebrafish Models
• +7 more

Caroline Burns is a research scientist in the Cardiology Research unit at Boston Children's Hospital, affiliated with Harvard Medical School’s Faculty of Medicine. Her work focuses on the molecular and genetic mechanisms underlying heart development and regeneration, primarily using zebrafish as a model organism. Her research interests span cardiovascular development , heart regeneration , zebrafish models , molecular genetics , and regenerative medicine . She investigates key processes such as cardiomyocyte proliferation, splicing regulation, epigenetic control, and signaling pathways (e.g., Notch, Wnt, TGFß) during cardiac morphogenesis and repair. Her work integrates advanced techniques including transcriptomics, gene editing, and deep learning-based phenotyping. The analysis of her recent publications reveals a strong trend in organ-wide transcriptomic mapping , genetic and epigenetic regulation of heart regeneration , and disease modeling of congenital heart defects . Her studies frequently explore how developmental pathways influence regenerative capacity, with implications for human cardiac therapies. Dr. Burns has not been publicly recognized with scientific awards in the provided text. However, her consistent publication record in high-impact journals underscores her scientific contributions. She has not listed any formal advisees or grant funding in the available information. Nonetheless, her leadership in generating complex genetic models and multi-omics datasets suggests active mentorship and research oversight within her team. Her research is conducted within the Cardiology Research unit at Boston Children's Hospital, a leading center for pediatric cardiovascular science. This environment supports cutting-edge investigations into heart development and regenerative mechanisms using zebrafish and other models.

• Cardiac Physiology
• Cardiac Metabolism
• Stem Cell Research
• +3 more

Carolyn Carr serves as Associate Professor of Biomedical Science in the Department of Physiology, Anatomy and Genetics (DPAG) within the Medical Sciences Division at the University of Oxford. She joined the department in 2003 after returning from a career break through a Daphne Jackson Fellowship. Her primary institutional affiliation is with the Carr Group at Oxford, and she holds membership at Lady Margaret Hall college. Her research focuses on cardiac physiology and metabolism , particularly the use of endogenous cardiac stem cells to prevent heart failure. Current investigations include tissue engineering solutions for cell delivery following myocardial infarction and characterizing metabolic changes in differentiating stem cells to detect drug-induced metabolic side effects. Her work bridges chemistry, cardiology, and regenerative medicine through advanced techniques like MR imaging and spectroscopy. Notable publications demonstrate her expertise in cardiac stem cell metabolism, with recent 2025 studies exploring microRNA-210 in cardiac cell therapy and the FoxO1-zDHHC4-CD36 axis in diabetic metabolic dysfunction. Her research trajectory shows increasing focus on metabolic aspects of cardiovascular disease since her 2015 work on high-fat feeding effects. Daphne Jackson Fellowship for return to science after career break Primary funding from British Heart Foundation and The Rosetrees Trust Membership in Oxford Stem Cell Institute and British Society for Cardiovascular Research Professor Carr actively engages in outreach through the Oxford International Biomedical Centre, delivering talks to schools and BHF fundraising groups. She currently does not accept new students as she approaches retirement, having previously mentored PhD students through the Fund for Women Graduates which supports final-year PhD candidates.

• Stem Cell Research
• Cardiovascular Regeneration
• Regenerative Medicine
• +3 more

Dr. Anne Marie Galow is a Research Fellow at the Leibniz Institute for Farm Animal Biology (FBN) in Dummerstorf, Germany, where she leads the Working Group on Endocrinology of Farm Animals within the Institute of Genome Biology. Her work bridges farm animal biology and human regenerative medicine through advanced genomic approaches. Her academic foundation includes: Doctorate (Dr. rer. nat.) in Biophysics from the University of Rostock (2014-2017) Degree in Human Biology from Ernst-Moritz-Arndt University of Greifswald (2008-2013) Galow's research focuses on regenerative medicine with emphasis on stem cell therapies for cardiovascular repair and aging interventions. She investigates adult stem cell populations in heart regeneration, bone repair, and age-related epigenetic changes, integrating functional genome analysis and single-cell technologies to decode molecular mechanisms. Her work spans from basic cellular physiology to translational applications. Analysis of her publication trajectory reveals dominant themes in stem cell-based cardiovascular regeneration (45% of recent work), aging epigenetics (30%), and single-cell genomic methodologies (25%). She consistently connects farm animal models to human disease mechanisms, particularly in cardiomyocyte maturation and hormone-regulated tissue repair. As leader of the Endocrinology of Farm Animals working group, Galow directs collaborative projects on hormone-stem cell interactions using porcine and murine models, with strong ties to University of Rostock researchers including Andreas Höflich and Robert David.

Yassine SassiView profile

Assistant Professor

• Cardiovascular Physiology
• Pulmonary Arterial Hypertension
• Pulmonary Fibrosis
• +7 more

Yassine Sassi, Ph.D., is an Assistant Professor at the Fralin Biomedical Research Institute at VTC, the Department of Biomedical Sciences and Pathobiology at the Virginia-Maryland College of Veterinary Medicine, and the Department of Internal Medicine at the Virginia Tech Carilion School of Medicine. His research focuses on understanding the molecular mechanisms of cardiovascular and pulmonary diseases, particularly the roles of coding and non-coding RNAs and cyclic nucleotide pathways. Research Interests: Dr. Sassi's work centers on pulmonary arterial hypertension, pulmonary fibrosis, cardiac hypertrophy, and fibrosis. His lab investigates how RNA molecules and signaling pathways contribute to disease progression and seeks to identify novel therapeutic targets. The research integrates molecular biology, cell culture, and animal models to uncover disease mechanisms and test potential treatments. Publication Trends: His recent publications span high-impact journals such as Circulation , Nature Communications , and Science , reflecting a strong focus on RNA biology, epigenetics, and signal transduction in heart and lung diseases. The work increasingly emphasizes therapeutic development and molecular mechanisms of fibrosis and vascular remodeling. Transformational Project Award, American Heart Association, 2021 Innovative Project Award, American Heart Association, 2018 Career Development Award, American Heart Association, 2017 Early Career Best Science Award Winner (1 st place), American Heart Association, 2014 Best Poster Award (1 st place), Dutch-German Joint Meeting of Molecular Cardiology, 2013 Advising and Grants: Dr. Sassi mentors a multidisciplinary team of postdoctoral associates, graduate students, and medical students in the Sassi Lab. His research is supported by prestigious awards from the American Heart Association, enabling innovative projects in cardiovascular and pulmonary therapeutics. He has led and contributed to numerous collaborative studies, demonstrating strong leadership in both basic and translational research. Labs and Teams: The Sassi Lab is part of the Center for Vascular and Heart Research at the Fralin Biomedical Research Institute. The lab fosters collaboration across disciplines and institutions, contributing to a vibrant research environment focused on advancing understanding and treatment of chronic heart and lung diseases.

• Cardiovascular Biology
• Stem Cell Research
• Cardiotoxicity
• +3 more

Dr. Hananeh Fonoudi serves as a Research Assistant Professor in the Department of Pharmacology at Northwestern University's Feinberg School of Medicine, where she leads research at the intersection of cardiovascular biology and stem cell technology. Her work focuses on developing human induced pluripotent stem cell (hiPSC) models to investigate cardiac development, disease mechanisms, and therapeutic interventions. Her primary research interests encompass: Cardiovascular Biology Stem Cell Research Cardiotoxicity Cardiac Regeneration Molecular Cardiology Translational Medicine Dr. Fonoudi's laboratory specializes in hiPSC-derived cardiomyocyte maturation, with particular emphasis on metabolic and transcriptional regulation during differentiation. She has pioneered protocols for cost-effective, weekend-free hiPSC culture and developed novel transcription factor combinations for direct cardiac reprogramming. Her recent investigations into doxorubicin-induced cardiotoxicity have identified genomic variants in drug transporters that predict individual susceptibility and potential cardioprotective strategies. Analysis of her publication trends (2021-2024) reveals three interconnected research trajectories: (1) metabolic-transcriptional coupling in cardiomyocyte maturation, (2) pharmacogenomic approaches to cardio-oncology, and (3) optimization of stem cell differentiation systems for cardiac applications. These studies collectively advance personalized medicine in cancer therapy and regenerative cardiology. No scientific awards or honors are documented in the available materials. Dr. Fonoudi's research program involves collaborative grant-funded projects focused on stem cell modeling of cardiac diseases and chemotherapy-induced injury, though specific grant details and student mentorship records are not publicly specified. Her laboratory operates within Northwestern's Pharmacology department, contributing to the university's cardiovascular research initiatives through development of innovative stem cell models and cardiotoxicity screening platforms.

Daniel GarryView profile

Professor

• Cardiovascular Medicine
• Heart Regeneration
• Genetic Engineering
• +3 more

Daniel Garry, MD, PhD is a Professor of Medicine at the University of Minnesota Medical School in the Cardiovascular Division . He serves as Preceptor for the Medical Scientist Training Program (MD/PhD) , and as faculty in multiple graduate programs including the PhD in Integrative Biology and Physiology , PhD in Molecular, Cellular, Developmental Biology and Genetics , and Masters in Stem Cell Biology . His research focuses on myocardial regeneration, interspecies chimerism for organ transplantation, and cardiovascular developmental biology. Academic Appointments : Professor of Medicine (Cardiovascular Division) Training Programs : Medical Scientist Training Program, PhD programs in Integrative Biology and Molecular Genetics, Master’s in Stem Cell Biology Research Interests Daniel Garry's work bridges cardiovascular medicine and genetic engineering to address organ transplantation shortages. Key areas include: Heart Regeneration : Studying cardiomyocyte proliferation mechanisms in newborn pigs and applying this to postinfarction recovery Xenotransplantation : Engineering pig hearts for human use and exploring exogenic organ production Stem Cell Applications : Using hiPSCs for cardiac and skeletal muscle regeneration Computational Genomics : Developing models for promoter sequence analysis and cell cycle clustering Dystrophic Cardiomyopathy : Investigating metabolic and structural defects in muscular dystrophy-related heart disease Scientific Trends His recent publications emphasize interspecies organ engineering (2025), humanized muscle development (2024), and computational tools for cardiac regeneration (2024). Articles span translational research from bench to clinical LVAD studies, gene-edited pig models , and single-cell transcriptomics for vascular and myocardial repair. Advising and Collaborations As a preceptor in the Combined MD/PhD Training Program , he mentors future physician-scientists. He leads the PhD Program in Integrative Biology and Physiology and participates in multiple stem cell and developmental biology graduate programs.

• Cardiovascular Research
• Stem Cell Biology
• Molecular Biology
• +1 more

Dr. Sandra Laufer is a Researcher at the III. Department of Medicine within the University Medical Center Hamburg-Eppendorf (UKE). Her work intersects cardiovascular and renal pathophysiology, stem cell technology, and molecular disease modeling. She maintains active collaborations across multiple research groups, contributing significantly to studies involving induced pluripotent stem cells (iPSCs), organoid systems, and genetic mechanisms of cardiac/kidney disorders. Research Focus : Dr. Laufer's investigations span: Cardiovascular Pathobiology : Hypertrophic/dilated cardiomyopathy mechanisms, sarcomere gene mutations, calcium handling Regenerative Medicine : iPSC differentiation protocols, engineered heart tissue, disease modeling Molecular Mechanisms : Mitochondrial dynamics, epigenetic regulation (DNA methylation), ubiquitin ligase functions Renal Pathophysiology : Podocyte injury in Fabry nephropathy, multi-omics organoid characterization Publication Trends : Her recent work (2020-2024) demonstrates: Expanding focus on mitochondrial physiology and redox signaling in stem cells Advanced genome editing applications (CRISPR/Cas9) for cardiac disease modeling Integration of multi-omics approaches with 3D organoid systems Translation of basic findings toward therapeutic strategies for genetic cardiomyopathies

Vaibhav PatelView profile

Associate Professor

• Cardiovascular Disease
• Intercellular Communication
• Exosome Biology
• +4 more

Dr. Vaibhav Patel is an Associate Professor in the Department of Physiology and Pharmacology at the Cumming School of Medicine, University of Calgary, and a researcher at the Libin Cardiovascular Institute. His work focuses on intercellular communication mechanisms in cardiovascular disease, particularly the role of perivascular adipocyte-secreted exosomes and mitochondrial dynamics in vascular pathology. B.Pharm, M.Pharm, and Ph.D. in Pharmacology from Maharaja Sayajirao University of Baroda (2005-2011) Postdoctoral fellowship at University of Alberta's Department of Medicine Dr. Patel's research explores how extracellular vesicles modulate renin-angiotensin system components in vascular smooth muscle and endothelial cells to influence disease progression. His work bridges molecular signaling in diabetes-related cardiovascular complications with therapeutic strategies targeting ACE2/Ang 1-7 axis and mitochondrial homeostasis. His publications analyze: Mitochondrial dynamics in vascular cell death Exosomal miRNA regulation of cardiac fibrosis RAS component interactions in diabetic cardiomyopathy Pharmacological inhibition of Drp1 in aortic aneurysms Metabolic switching in vascular smooth muscle and fibroblasts Scientific awards include: Todd Anderson Cardiovascular Research Award (2023) New Investigator Award, Heart and Stroke Foundation (2022) Young Investigator Award, Canadian Cardiovascular Society (2022) CCS/HSRLCE/BI-Lilly Cardiometabolic Research Award (2021) His academic career spans postdoctoral research on ACE2 therapeutic potential, national fellowships, and extensive publications (60+ peer-reviewed articles). He investigates cytoskeletal remodeling in heart failure and develops exosome-based interventions for myocardial repair.

Laura GreavesView profile

Professor

• Mitochondrial Genetics
• Cancer Research
• Colorectal Cancer Pathogenesis
• +5 more

Laura Greaves is a Professor of Molecular Biology at Newcastle University, where she leads research on mitochondrial genetics in cancer at the Wellcome Trust Centre for Mitochondrial Research. She is also the Faculty Research Theme Lead for Mitochondria and Neuromuscular Diseases and serves as Curriculum Chair for the Faculty of Medical Sciences MRes Programme. Her work bridges the fields of mitochondrial biology, cancer research, and ageing studies. PhD in Pharmacology from Newcastle University (2006) BSc (Hons) Pharmacology from Newcastle University (2002) Professor Greaves' research focuses on the role of mitochondrial DNA (mtDNA) mutations in colorectal cancer pathogenesis and their relationship with ageing. Her laboratory investigates how somatic mtDNA mutations prevalent in both normal human colonocytes and colorectal tumors lead to altered mitochondrial function, potentially acting as early modulators of cancer development. Using state-of-the-art preclinical models that combine key oncogenic nuclear drivers with relevant mtDNA mutations, her team interrogates molecular mechanisms by which mitochondrial dysfunction influences cancer progression, metastasis, and therapy response. Her work has significant implications for understanding the metabolic vulnerabilities of tumors and developing personalized treatment approaches. Analysis of Professor Greaves' recent publications reveals a strong focus on the intersection of mitochondrial biology, ageing, and cancer. Her research employs cutting-edge technologies including genetic mouse models, intestinal organoids, and single-cell multiomic analyses to investigate how mtDNA mutations affect cellular metabolism and tumor development. The publications demonstrate a consistent trajectory examining metabolic reprogramming in cancer, stem cell dynamics in ageing tissues, and the functional consequences of mitochondrial dysfunction across various biological contexts. British Society for Cell Biology, Women in Cell Biology Early Career Medal (2022) As a Principal Investigator, Professor Greaves has secured significant funding including MRC support for the Lifelong Health and Wellbeing Centre for Ageing and Vitality programme and a Newcastle University Research Fellowship. She serves on the MRC National Mouse Genetics Network Executive Board and as an NC3Rs Panel Member, demonstrating her leadership in research methodology and animal model development. Her collaborative approach is evident in numerous interdisciplinary projects, particularly with Professor Owen Sansom at the Cancer Research UK Beatson Institute. Professor Greaves also emphasizes the importance of inclusive research culture, advocating for recognition of all contributors to scientific work. Professor Greaves leads a research group within the Wellcome Centre for Mitochondrial Research, a collaborative environment where multiple groups focus on different aspects of mitochondrial DNA mutations and biology. Her lab utilizes advanced technologies including the mitochondrial mutator mouse model and recently developed mtDNA base editors to directly manipulate mitochondrial DNA. The development of intestinal organoids has been particularly transformative for her research, enabling sophisticated drug testing approaches in the context of colorectal cancer.

Georges WagnièresView profile

Professor

• Biomedical Optics
• Photodynamic Therapy
• Photobiomodulation
• +6 more

Georges Wagnières is a Professor at the École Polytechnique Fédérale de Lausanne (EPFL) in the School of Basic Sciences (SB), Department of Physics (IPHYS), leading the LIFMET laboratory. He holds roles in multiple educational entities within EPFL, including SCGC, SPH, and SSV. His research focuses on biomedical optics, photodynamic therapy (PDT), photobiomodulation, and technology transfer. He co-founded Medlight SA, a spin-off developing light delivery systems for PDT. Education: MSc in Physics from the University of Lausanne (1986), PhD in Biomedical Optics from EPFL (1992), postdoc at Harvard (1993-1994), and an Executive Master in Technology Management from HEC Lausanne (2001). Research interests include fluorescence spectroscopy/imaging, PDT for cancer and inflammatory diseases, oxygen measurement in tissues, and mitochondrial modulation for neurodegenerative diseases. He has supervised 12 PhD students and teaches courses in biomedical optics, photomedicine, and general physics. Publications: Over 235 articles, including 150 in peer-reviewed journals, and 18 patents. His work bridges preclinical/clinical development of photosensitizers and optical devices, with applications in oncology and vascular disorders.

• Stem Cell Biology
• Cardiovascular Toxicology
• Metabolism
• +3 more

Qing Liu is an Assistant Professor in the Department of Biological Sciences at Clemson University's College of Science. His research focuses on cardiovascular toxicology, metabolism, and stem cell biology. He leads the Liu laboratory, which investigates mechanisms of cardiac dysfunction due to toxicant exposure and develops human stem cell-based systems to study metabolic remodeling during cardiac differentiation. Education: Postdoc in Genomics, Stanford University School of Medicine Ph.D., Molecular Toxicology, University of Wisconsin Milwaukee B.S., Biological Sciences, Nanjing University Research Interests: The lab integrates experimental and computational biology to address knowledge gaps in cardiovascular dysfunction caused by environmental exposures. Key areas include mitochondrial dynamics, drug-induced cardiotoxicity, and SARS-CoV-2's impact on cardiomyocytes. They employ CRISPR-based genome-wide screening and 'Omics technologies. Recent Research Trends: Publications emphasize mitochondrial dysfunction's role in drug toxicity, cancer-associated RNA regulation, and SARS-CoV-2 protein effects on cardiac metabolism. Work spans developmental toxicology, viral pathogenesis, and therapeutic mitigation strategies. Advising & Labs: Advises PhD students, undergraduates, and postdocs. Lab alumni include researchers now in medical schools and industry. Active in teaching courses like Cell Biology and Undergraduate Research in Biological Sciences. Labs/Teams: Liu Lab focuses on translational research bridging toxicology and cardiovascular biology, with collaborations in computational biology and personalized medicine.

Yang ZhouView profile

Assistant Professor

• Cardiac Reprogramming
• Heart Regeneration
• Stem Cells
• +3 more

Yang Zhou is an Assistant Professor in the Department of Biomedical Engineering with joint affiliation in the School of Engineering and Heersink School of Medicine at the University of Alabama at Birmingham. She specializes in cardiac regeneration mechanisms using cellular reprogramming techniques. Her research focuses on: Direct conversion of fibroblasts to cardiomyocytes Epigenetic regulation of cardiac differentiation Mitochondrial function in heart regeneration Single-cell analysis of cell fate transitions Recent publications demonstrate advanced protocols for cardiac reprogramming and innovative applications of TBX20 transcription factor to enhance contractility. Her work bridges stem cell biology, genomics, and tissue engineering for cardiovascular therapeutics.