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Daniel Finley is a Professor of Cell Biology at Harvard Medical School (HMS), leading the Finley Lab focused on the ubiquitin-proteasome pathway and related regulatory mechanisms. He holds academic appointments within the Department of Cell Biology and sits on the Scientific Advisory Boards of Proteostasis and X-Chem Pharmaceuticals. His research investigates proteasome function, ubiquitin-like proteins, and proteostasis roles in diseases like Alzheimer’s and ALS. Dr. Finley earned his undergraduate degree in biochemistry from Harvard University and a Ph.D. in molecular biology from MIT. After postdoctoral training at MIT, he joined HMS in 1988. His lab explores topics including erythroid proteome remodeling, mitochondrial dysfunction, and neurodegenerative disease mechanisms. Key research areas include: (1) Ubiquitin-proteasome pathway regulation, (2) Proteasome structure/function, (3) Nonproteolytic roles of ubiquitination, and (4) Pathophysiological roles of proteostasis defects in diseases. His work bridges basic cell biology with translational medicine, particularly in neurodegeneration and anemia. Finley has secured NIH funding for projects like 'Regulation of Proteasome Activity' (R35GM145246) and 'Erythrocyte maturation through global proteome remodeling' (R01HL153970). Collaborations with industry and academic partners extend his impact in drug discovery and proteasome-targeted therapies. His lab’s contributions include defining ubiquitin chain editing mechanisms, identifying USP14’s role in mitophagy, and elucidating proteostasis defects in Alzheimer's models. Research tools developed include advanced cryo-EM analyses of proteasomal structures and functional assays for ubiquitin system enzymes.

• Ubiquitin-Proteasome Pathway
• Proteostasis
• Protein Degradation
• +7 more

Vivek Shenoy is the Eduardo D. Glandt President's Distinguished Professor at the University of Pennsylvania, with primary appointments in the Department of Materials Science and Engineering and secondary appointments in Bioengineering and Mechanical Engineering and Applied Mechanics. He leads the Multiscale Mechanobiology and Biomaterials Laboratory, which focuses on developing theoretical frameworks and numerical methods to understand complex biological and engineering systems across multiple length scales. Shenoy's research spans mechanobiology, chromatin organization, cell mechanics, and biomaterials. His work addresses the fundamental challenge of modeling how small-scale cellular phenomena couple with long-range tissue-level interactions across micrometers to centimeters. By integrating insights from soft matter physics, solid mechanics, chemistry, and applied mathematics, his group develops multiphysics continuum and mesoscale theories to elucidate mechanisms controlling both biological and engineering systems. His recent publications demonstrate an increasing focus on nuclear mechanics, chromatin organization, and the interplay between mechanical forces and gene regulation. Analysis of Shenoy's publication record reveals a strong interdisciplinary approach, with high-impact papers spanning biophysics, materials science, and cell biology. His work shows consistent evolution from fundamental mechanics of materials to complex biological systems, with recent emphasis on the mechanical regulation of chromatin architecture, cell migration dynamics in 3D environments, and mechanotransduction in development and disease. His publications appear regularly in top journals including Nature, Science, and their affiliated publications, demonstrating significant influence across multiple fields. Eduardo D. Glandt President's Distinguished Professor Multiple publications in Nature, Science, and PNAS Active research program with publications through 2025 Shenoy actively mentors students and postdocs through his laboratory, with numerous co-authored publications indicating strong mentorship. His research program appears to be well-funded through multiple grants supporting his work in mechanobiology and biomaterials. The Multiscale Mechanobiology and Biomaterials Laboratory maintains active collaborations across disciplines and institutions, reflecting the interdisciplinary nature of his research. The Multiscale Mechanobiology and Biomaterials Laboratory, housed within the Department of Materials Science and Engineering at the University of Pennsylvania, serves as the primary research hub for Shenoy's work. The lab maintains an active presence on social media (Twitter: @ShenoyLab) for updates on activities and publications. Their research approach combines theoretical modeling with experimental validation to address fundamental questions at the interface of mechanics, materials science, and biology.

• Mechanobiology
• Multiscale Modeling
• Biomaterials
• +6 more

Martin T. Wells is the Charles A. Alexander Professor of Statistical Sciences at Cornell University, with joint appointments in the Department of Statistical Science, Department of Biological Statistics and Computational Biology, Department of Social Statistics, and as Professor of Clinical Epidemiology and Health Services Research at Weill Medical School. He serves as Editor-in-Chief of the ASA-SIAM Book Series and Co-Editor of the Journal of Empirical Legal Studies. Cornell University, Ithaca, NY Weill Cornell Medical College Research Interests span applied and theoretical statistics, Bayesian methods, biostatistics, clinical epidemiology, and computational biology. His work bridges disciplines like finance, legal studies, and health services research. Article Trends highlight advancements in Bayesian modeling, quantum cognition machine learning, tensor analysis, and misclassification correction, with applications in genomics, finance, and public health. Fellow of the American Statistical Association Fellow of the Royal Statistical Society Contributions include developing statistical software (e.g., rTensor), methodological innovations in clinical trials, and empirical legal studies on civil rights and the death penalty.

• Applied Statistics
• Theoretical Statistics
• Bayesian Statistics
• +7 more

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

• Biological Physics
• Biophysics
• Theoretical Physics
• +3 more

Ting Lu is an Associate Professor at the University of Illinois at Urbana-Champaign in the School of Biomedical and Translational Sciences, focusing on microbial synthetic biology and systems biology. Their research bridges biology, engineering, and physics to reprogram cellular functionalities through gene regulatory networks. Ph.D. in Biophysics, University of California at San Diego (2007) B.S. in Physics, Zhejiang University (2002) Ting Lu's work explores microbial ecosystems, synthetic gene circuits, and their applications in biotechnology and medicine. By combining experimental approaches with mathematical modeling, they investigate bacterial communication networks, metabolic pathways, and spatial dynamics in microbial communities. Selected research trends include microbial consortia engineering for bioremediation and bioproduction, complexity reduction in microbiomes, and predictive modeling of synthetic gene networks. Their publications span high-impact journals such as Nature Communications , Nature Chemical Biology , and eLife . Fellow, American Institute for Medical and Biological Engineering (2022) Future Insight Prize (2021) Donald Biggar Willett Faculty Scholar (UIUC) (2020) NIH Maximizing Investigators' Research Award (2019) NSF CAREER Award (2015) AHA National Scientist Development Grant (2012) Ting Lu's lab has received grants from NIH, NSF, ONR, and industry partners. They offer undergraduate research opportunities in synthetic and systems biology, and teach advanced courses such as BIOE 430 - Intro Synthetic Biology and BIOE 432 - Systems Biology .

• Synthetic Biology
• Systems Biology
• Quantitative Biology
• +5 more

Bradley D. Olsen is a full professor in the Department of Chemical Engineering at the Massachusetts Institute of Technology (MIT), where he leads research at the intersection of polymer science, soft matter physics, and bioengineering. His work focuses on designing materials for critical applications in biotechnology, hemostasis, and sustainable polymer development while advancing fundamental understanding of polymer network mechanics and self-assembly. Education: Ph.D. in Chemical Engineering, University of California Berkeley (2007) S.B. in Chemical Engineering, Massachusetts Institute of Technology (2003) Olsen's research spans protein-based materials, block copolymer phase behavior, and mechanochemical hydrogels. He has pioneered methods for quantifying polymer network topology, developing hemostatic nanoparticles, and creating bio-inspired materials for selective biomolecular transport and medical applications. His recent publications emphasize data-driven approaches to polymer characterization and educational outreach in materials science. Scientific Awards: American Physical Society (APS) Fellow (2023) Fulbright Amazonia Scholar (2023) Alexander and I. Michael Kasser Chair in Chemical Engineering (2021) ACS Macro Letters Young Investigator Award (2021) MIT Committed to Caring Honor (2019) AIChE Owens Corning Early Career Award (2019) APS Dillon Medal (2018) Kavli Emerging Leader in Chemistry (2017) ACS Polymer Division Fellow (2016) Camille Dreyfus-Teacher Scholar (2015) Alfred P. Sloan Research Fellow (2014) NSF Career Grant (2013) NIH Postdoctoral Fellowship (2008-2009) Hertz Fellow (2003-2007) Barry M. Goldwater Scholarship (2002) Olsen has received significant grant support including NSF Career (2013) and AFOSR (2012) awards. His teaching activities include innovative international outreach like the 2025 soccer-themed science camp in Brazil. The Olsen Group at MIT explores advanced materials with applications ranging from trauma care to sustainable polymers.

• Polymer Science
• Materials Engineering
• Soft Condensed Matter Physics
• +4 more

Andre Levchenko is the John C. Malone Professor of Biomedical Engineering at Yale University, with secondary appointments in the Department of Neurosurgery and affiliations with the Cancer Signaling Networks, Immunology, and the Yale Program in Neurodevelopment and Regeneration. His research focuses on systems biology, signal transduction, and cell-cell communication, utilizing microfluidics and computational modeling to study cancer progression, stem cell behavior, and neurological disorders. PhD, Columbia University MEng, Moscow Institute of Physics and Technology Levchenko's work explores how cells process dynamic signals to make critical decisions, particularly in glioblastoma migration, organoid development, and cardiovascular tissue engineering. His lab develops innovative microfluidic platforms and mathematical models to dissect multicellular communication and signaling networks. Recent publications highlight his contributions to understanding YAP-driven cancer invasion , NOTCH signaling in angiogenesis , and metabolic regulation of hypoxia responses . He has pioneered methods for organoid modeling and single-cell analysis , advancing precision in biological signaling studies. Scientific Awards : Computational Molecular Biology Post-Doctoral Fellowship (Burroughs Wellcome Fund) National Academies Keck Futures Conference Invitee Distinguished Guest Lecturer, University of Virginia American Asthma Foundation Early Excellence Award Fellow, American Institute for Medical and Biological Engineering Levchenko leads the Levchenko Lab at the Yale Systems Biology Institute, collaborating with institutions like Mayo Clinic and Yale Cancer Center. His research has received recognition in Faculty of 1000 and multiple journal highlights.

• Systems Biology
• Signal Transduction
• Cell Communication
• +5 more

Dr. Giulia Biancon is an Assistant Professor Adjunct in the Department of Medical Oncology and Hematology at Yale School of Medicine. She holds a PhD from the University of Milan (2019) and is a member of the Halene Lab, focusing on RNA biology and hematologic malignancies. Her research combines high-throughput methodologies to study RNA mechanisms in diseases like myeloid leukemias and splicing factor mutations. Education: PhD in Molecular Biology from the University of Milan (2019). Research Interests: RNA splicing, stress granules in cancer, epitranscriptomics, clonal hematopoiesis, and the interplay between genetic mutations and cellular pathways in blood cancers. Awards: 2024 Eclipse Award, 2022 ASH Abstract Achievement Award, and 2022 RNA Society Best Poster Award. Her work has been published in journals like Cell Reports , Blood , and Molecular Cell . Labs/Teams: Principal member of the Halene Lab and coordinator at the Yale Center for RNA Science and Medicine. Collaborates with institutions like the SeroNet network for immunology studies.

• RNA Biology
• Myeloid Malignancies
• Hematology
• +4 more

Yao Qin is an Assistant Professor in the Department of Electrical and Computer Engineering at the University of California, Santa Barbara (UCSB), with dual affiliation in the Department of Computer Science. She concurrently serves as Co-Director of the REAL AI Initiative at UCSB and holds a Senior Research Scientist position at Google DeepMind, where she contributes to the Gemini Multimodal project. Her academic credentials include a PhD in Computer Science and Engineering from the University of California, San Diego (advised by Prof. Garrison W. Cottrell) and a BS in Electrical Engineering from Dalian University of Technology. During her doctoral studies, she completed internships with pioneering researchers Geoffrey Hinton and Ian Goodfellow. Dr. Qin's research program centers on machine learning robustness, with emphasis on adversarial robustness, out-of-distribution generalization, and fairness. She develops reliable AI systems specifically for healthcare applications, with diabetes management as a primary focus. Her lab explores critical themes including AI safety in multimodal models and diabetes-specific AI solutions, particularly exercise metabolism modeling and glycemic effect prediction. Recent publications reveal a strong trajectory in robust machine learning with cross-domain applications. Her work consistently bridges theoretical robustness concepts with practical healthcare implementations, particularly in diabetes care. Key publication venues include CVPR, ICML, NeurIPS, and ICLR, with notable contributions to out-of-distribution detection, adversarial transfer learning, and multimodal AI safety. Her distinguished recognition includes: EECS Rising Star at MIT (2021) UCSB Regents' Junior Faculty Fellowship Award Helmsley Charitable Trust award for Type 1 diabetes research UCSB Faculty Research Grant American Diabetes Association Abstract Award (ADA-2025) Dr. Qin actively mentors four PhD students—Mehak Dhaliwal, Andong Hua, Kenan Tang, and Youngseok Yoon—on projects spanning LLMs for diabetes, multimodal robustness, and generative time-series modeling. Her research is funded by the Helmsley Charitable Trust and UCSB, with recent grants supporting exercise-specific AID algorithms for diabetes management. As Co-Director of the REAL AI Initiative, she leads a research ecosystem focused on developing reliable artificial intelligence. Current lab activities include organizing workshops at NeurIPS-2024 (AdvML-Frontiers and AIM-FM) and developing next-generation diabetes management tools through collaborations with medical institutions.

• Machine Learning
• Adversarial Robustness
• Out-of-Distribution Generalization
• +5 more

Professor Daniel Segrè is a faculty member at Boston University, holding the title of Professor of Biology, Bioinformatics, and Biomedical Engineering. His research focuses on systems biology, microbial ecology, and metabolic engineering, with an emphasis on understanding complex biological networks and their applications in bioenergy and biomedicine. Segrè leads the Segre Lab ( segrelab.bu.edu ), where theoretical and computational approaches are applied to study metabolism, microbial interactions, and synthetic biology. Segrè earned his PhD from the Weizmann Institute of Science, Israel. His work bridges fundamental science and applied engineering, addressing topics such as microbial community dynamics, metabolic pathway design, and environmental microbiome applications. Research Interests: Systems biology of metabolism, evolution of biochemical networks, microbial interactions, bioinformatics, and environmental microbiome engineering. His lab develops computational models (e.g., COMETS) to simulate microbial ecosystems and design synthetic microbial communities for climate change mitigation and bioenergy production. Teaching: Courses include BE 777 (Computational Genomics), BF 821 (Bioinformatics Seminar), and BF 571 (Dynamics and Evolution of Biological Networks). These courses reflect his expertise in integrating computational methods with biological systems analysis.

• Systems Biology
• Metabolic Engineering
• Microbial Ecology
• +7 more

Mengliang Zhang is an Associate Professor in the Department of Chemistry and Biochemistry at Ohio University, College of Arts and Sciences. He leads an interdisciplinary research group focused on mass spectrometry and chemometrics, with applications in forensic, food, agricultural, environmental, and material sciences. His lab develops innovative analytical strategies for detecting toxicants, characterizing nanomaterials, and profiling metabolites in botanicals and food systems. Ph.D., Chemistry, Ohio University, 2015 Dr. Zhang’s research integrates instrumentation, chemometrics, and computational tools to address complex analytical challenges. His group works on forensic fiber and ignitable liquid analysis, plant metabolomics, nanomaterial surface chemistry, and environmental toxicant monitoring. His work is highly interdisciplinary, bridging chemistry, data science, and real-world applications in forensics and public health. His recent publications demonstrate a strong trend in advancing ambient ionization mass spectrometry (especially DART-MS), chemometric modeling, and metabolite profiling across diverse matrices—from fire debris to broccoli microgreens. His work increasingly emphasizes automation, quantitation, and database development for botanical phytochemicals. Scientific honors include the MTSU Distinguished Research Award (Early Career), and his students have received prestigious awards such as the Goldwater Scholarship and multiple URECA recognitions. He is actively supported by federal grants from NSF, USDA, DOE, DOJ (NIJ), and FEMA. Dr. Zhang mentors a vibrant research team of graduate and undergraduate students, guiding them in publishing high-impact research and presenting at national conferences like ASMS, Pittcon, and AAFS. He has organized sessions at SciX and served on editorial boards of Journal of Forensic Sciences and Journal of AOAC INTERNATIONAL . His lab recently relocated to Ohio University in August 2024, equipped with advanced instrumentation including UHPLC-QTOF-MS and DART-MS systems.

• Forensic Chemistry
• Food and Agricultural Chemistry
• Metabolomics
• +12 more

Wing Lam is an Associate Research Scientist in the Department of Pharmacology at the Yale School of Medicine. He holds a BSc in Molecular Biology and a PhD in Biochemical Pharmacology from City University of Hong Kong, followed by postdoctoral training at Yale. His research focuses on developing traditional Chinese medicine (TCM) formulations as adjuvants for cancer therapy, notably YIV-906, which enhances chemotherapy efficacy and mitigates intestinal toxicity. Lam also pioneered the STAR database for herbal drug discovery and the Mechanism-Based Quality Control (MBQC) platform for botanical drug standardization. Education: BSc (Hons) Molecular Biology, City University of Hong Kong, 1995 PhD Biochemical Pharmacology, City University of Hong Kong, 1999 Postdoc, Pharmacology, Yale University, 1999-2002 His research interests span cancer pharmacology, TCM modernization, and mitochondrial toxicity mechanisms. Key projects include YIV-906’s role in enhancing anti-PD1 and CAR T-cell therapies, developing L-nucleoside analogs like troxacitabine, and investigating tylophorine analogs’ antitumor effects. Lam has co-chaired sessions at multiple Consortium for Globalization of Chinese Medicine (CGCM) meetings and contributed to patents on herbal drug formulations and quality control methods. Recent work explores YIV-906’s potential for inflammatory bowel disease (IBD) and phase II clinical trials for colon and liver cancers. Lam’s publications highlight synergistic drug interactions, mitochondrial DNA depletion mechanisms, and TCM’s evidence-based application in chronic diseases. His grants include studies on PHY906 as an adjuvant in rectal cancer therapy and collaborations with Yiviva, Inc. He maintains active roles in editorial boards, including a special issue on herbal drug quality control in Frontiers in Pharmacology . Lam’s lab is embedded within Dr. Yung-Chi Cheng’s group, focusing on translational pharmacology and botanical drug innovation.

• Pharmacology
• Traditional Chinese Medicine
• Cancer Therapy
• +7 more

Amilcare Porporato is the Thomas J. Wu '94 Professor of Civil and Environmental Engineering at Princeton University, with joint appointment at High Meadows Environmental Institute. His research integrates hydrology, ecology, and thermodynamics to study soil-water interactions and sustainable resource management. Education includes: Ph.D. Polytechnic of Milan (1996) M.S. Civil Engineering, Polytechnic of Milan (1992) Research explores nonlinear hydrologic systems, soil moisture dynamics, ecohydrology, and environmental complexity using theoretical and experimental approaches. His work advances understanding of water-biota interactions across scales from pore-level processes to landscape evolution. Honors and Awards: Hydrologic Sciences Award, AGU Borland Lecturer American Geophysical Union Fellow Inaugural Landolt Chair, EPFL Teaches courses on Environmental Thermodynamics (ENV 385/CEE 385) and Ecohydrology (CEE 587/ENV 587).

• Ecohydrology
• Soil-Atmosphere Interaction
• Hydrologic Time Series
• +2 more

Dr. Steven G. Clarke is a Distinguished Professor at UCLA Department of Chemistry & Biochemistry and director of research at the Molecular Biology Institute . His work bridges protein chemistry , methylation biology , and aging research through studies of spontaneous protein damage and its repair mechanisms. Education: BA in Chemistry and Zoology, Pomona College (magna cum laude, Phi Beta Kappa) PhD in Biochemistry and Molecular Biology, Harvard University (NSF Fellow) Postdoctoral Fellowship at UC Berkeley (Miller Fellow) Dr. Clarke's research focuses on protein isoaspartyl repair via PCMT1/PIMT enzymes , ribosomal protein methylation in Saccharomyces cerevisiae , and PRMT family characterization including PRMT7 and PRMT9. His lab combines biochemical assays , genetic models , and structural analysis to investigate aging mechanisms and disease implications. Recent publications highlight: COQ5 structure-function analysis in coenzyme Q biosynthesis PCMTD1 ubiquitin ligase interactions PRMT7 substrate specificity in histone H2B Protein isoaspartyl impacts on T cell function in lupus Novel PRMT inhibitors for cancer therapy Methionine addiction in osteosarcoma malignancy Major scientific awards: American Chemical Society Ralph F. Hirschmann Award in Peptide Chemistry NIH MERIT Award Ellison Medical Foundation Senior Scholar Award William C. Rose Award, ASBMB UCLA Distinguished Teaching Award (Eby Award winner) Current lab members include PhD candidates Eric Pang (UCSB) and Sining "Cindy" Wang (UCLA), while undergraduates Celeste Medina-Seymoure , Elizabeth Oroudjeva , Olivia Pacheco , and Jasmine Winter contribute to ongoing proteostasis studies. Collaborations with Profs. Jose Rodriguez and Catherine Clarke demonstrate interdisciplinary research approaches.

• Biochemistry
• Systems Biology
• Biological Regulation
• +8 more

Angela D. Kent is a Professor in the Department of Natural Resources and Environmental Sciences at the University of Illinois Urbana-Champaign, where she also serves as Director of the Program in Ecology, Evolution, and Conservation Biology within the School of Integrative Biology. She is affiliated with the Carl R. Woese Institute for Genomic Biology. Her research focuses on microbial communities in agroecosystems and natural environments, particularly their roles in nitrogen cycling, soil health, and sustainable bioenergy production. Key research interests include microbial interactions in plant-microbe systems, the impact of genetic variation in crops on microbial processes, and the ecological and biogeochemical implications of soil microbiomes. She has authored over 99 publications and supervised datasets on topics such as denitrification dynamics, rhizosphere microbiome assembly, and microbial contributions to nitrogen retention. Dr. Kent has received the NACTA Educator Award (2012) and has contributed to high-impact studies on topics like microbial community responses to environmental stressors and the application of stable isotopes in bioenergy research. Her work bridges microbial ecology, agronomy, and environmental science, emphasizing practical solutions for sustainable agriculture and ecosystem management.

• Microbial Ecology
• Nitrogen Cycling
• Agroecosystems
• +3 more