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Marzena Mogielnicka-BrzozowskaView profile

Associate Professor

• Andrology of Pets and Companion Animals
• Proteomics of the Male Reproductive System
• Aging of the Canine Epididymis
• +3 more

Marzena Mogielnicka-Brzozowska is an Associate Professor at the University of Warmia and Mazury in Olsztyn, affiliated with the Department of Biochemistry and Animal Biotechnology under the Faculty of Animal Bioengineering. Her research focuses on proteomic and biochemical aspects of male reproductive systems in companion and farm animals, including proteomic profiling of seminal plasma, zinc-binding proteins in reproductive processes, and molecular biomarkers of fertility. She has supervised one doctoral student and currently oversees another. Research Interests Her work explores proteomic analysis of canine and boar seminal plasma , zinc-binding proteins in sperm function regulation , and oxidative stress markers in cryopreserved semen . She investigates age-related proteomic changes in the canine epididymis and seasonal effects on stallion and boar spermatozoa. Scientific Contributions Recent publications highlight her expertise in reproductive biotechnology , with studies on PLAGL1 transcript isoforms in cancer , antioxidant status of boar seminal plasma , and zinc-protein interactions in equine and canine reproduction . Despite no listed awards, her work has been cited over 500 times (Google Scholar), reflecting significant impact. Collaborative Networks She collaborates with researchers at institutions like the University of Manitoba and Wrocław University of Environmental and Life Sciences. Her lab contributes to understanding sperm proteomics and seminal plasma composition for improved reproductive technologies.

• Cell Biology
• Molecular Biology
• Cilia Research
• +2 more

Zeinab Anvarian serves as a Guest researcher at the Department of Biomedical Sciences, University of Copenhagen, affiliated with the Core Facility for Integrated Microscopy. Her research focuses on cellular mechanisms with particular emphasis on cilia biology and protein dynamics within cellular structures. Dr. Anvarian's research interests center on cell biology with specialization in ciliary function, protein trafficking mechanisms, and molecular regulation of cellular structures. Her work integrates advanced imaging techniques with proteomic approaches to investigate how motor proteins like KIF13B regulate ciliary composition and signaling pathways. She has made significant contributions to understanding the role of scaffold proteins in ciliary targeting and the mechanisms controlling extracellular vesicle release from cilia. Analysis of her recent publications reveals a strong thematic focus on ciliary protein regulation, with recurring investigation of KIF13B's multifaceted roles in ciliary transport and signaling. Her work spans methodological development in live-cell imaging to detailed proteomic characterization of ciliary components, demonstrating both technical innovation and deep biological insight into cellular mechanisms related to ciliopathies and cellular signaling disorders. Dr. Anvarian maintains active collaboration with researchers across multiple institutions, as evidenced by her extensive co-authorship network. Her work has garnered attention across academic platforms with significant readership on Mendeley and social media sharing by researchers worldwide.

Stephen AlexanderView profile

Associate Professor

• Pharmacology of G protein-coupled receptors
• Cannabinoid receptor pharmacology
• Endocannabinoid system
• +12 more

Stephen Alexander is an Associate Professor of Molecular Pharmacology at the University of Nottingham's Faculty of Medicine & Health Sciences within the School of Life Sciences. His research focuses on the pharmacology and biochemistry of G protein-coupled receptors, particularly cannabinoid, adenosine and glutamate receptors, with significant contributions to the understanding of endocannabinoid signaling and drug mechanisms. Dr. Alexander's research interests span several interconnected areas centered on receptor pharmacology and signaling. His primary work investigates the endogenous cannabinoid system, particularly its role in inflammation and pain pathways, with notable publications on vasoactivity of anandamide, neuroprotection via cannabinoid activation of PPARα, and regulation of dopaminergic neurotransmission. A significant portion of his research explores signaling cross-talk between different receptor systems and agonist bias at G protein-coupled receptors. Additional research areas include enzyme turnover of endocannabinoids, hydrogen sulphide signaling, and mitochondrial function in cell survival following drug exposure. His publication record demonstrates a consistent focus on cannabinoid pharmacology and receptor signaling, with recent work emphasizing the endocannabinoid system's role in schizophrenia, novel endocannabinoid compounds, and the biochemical mechanisms underlying receptor signaling. The articles show a progression from basic receptor pharmacology to more complex systems biology approaches, with significant contributions to pharmacological reference works like the IUPHAR/BPS Guide to PHARMACOLOGY. Dr. Alexander has been featured in multiple media outlets including BBC Radio Nottingham, BBC Radio 4, BBC Scotland, BBC News 24, BBC3, and BBC1, discussing topics related to cannabis, caffeine, and food science, demonstrating his ability to translate complex pharmacological concepts for public understanding. His research methodology combines molecular pharmacology techniques with biochemical and physiological approaches, often working with isolated tissues, cultured cells, and enzyme assays. Current projects focus on signaling convergence through Epac pathways and the role of N-arachidonoylglycine in pancreatic insulin secretion, indicating continued active research in novel signaling pathways.

• Neuroscience
• Neuropharmacology
• Drug Addiction Research
• +5 more

Claus Juul Løland is an Associate Professor in the Department of Neuroscience within the Faculty of Health and Medical Sciences at the University of Copenhagen. His research focuses on neuropharmacology, particularly examining the biochemical effects of substances like cocaine and amphetamines in the brain, addiction mechanisms, and the dopamine reward system. Position: Associate Professor Institution: University of Copenhagen Department: Department of Neuroscience Research Group: Neuropharm and Genetics Location: Blegdamsvej 3B, 2200 Copenhagen N Løland's primary research interests center on understanding drug addiction mechanisms, particularly related to cocaine and amphetamines, with specific expertise in the dopamine transporter system. His work investigates how these substances interact with brain chemistry to produce addictive behaviors, including research on smoking addiction and the dopamine reward system. His laboratory employs advanced biochemical and structural biology techniques to study neurotransmitter transporters at the molecular level. Analysis of his recent publications (2024-2025) reveals a strong focus on membrane protein biochemistry, particularly neurotransmitter transporters. His work combines structural biology approaches (including NMR spectroscopy) with medicinal chemistry to understand how psychoactive substances like cocaine interact with their molecular targets. A significant portion of his recent work involves developing novel detergents for membrane protein stabilization, which is crucial for structural studies of neurotransmitter transporters. Løland leads the Løland-lab at the University of Copenhagen, which maintains an active research program with numerous international collaborations. His work has been featured in major media outlets including TV2 Nyhederne and other Danish news media, particularly around breakthroughs in understanding cocaine's mechanism of action in the brain.

Xiangfa WuView profile

Professor

• Renewable Energy Harvesting, Conversion & Storage
• Multifunctional Nanofibers & Nanostructures
• Polymer Matrix Composites (PMCs) & Joining Technologies
• +1 more

Xiangfa Wu is a Professor in the Department of Mechanical Engineering at North Dakota State University, specializing in advanced materials and energy systems. His work bridges theoretical mechanics with practical applications in sustainable technology development. Education Ph.D. in Engineering Mechanics, University of Nebraska Ph.D. in Applied Mathematics, Beijing Institute of Technology M.S. in Applied Mechanics, Beijing Institute of Technology Research Focus Dr. Wu's research program centers on four interconnected domains: renewable energy systems spanning harvesting, conversion, and storage technologies; engineered nanofibers and nanostructures with multifunctional capabilities; polymer matrix composites and advanced joining methodologies; and computational approaches to micro/nanomechanics. His work consistently integrates fundamental mechanics principles with materials innovation for energy applications. Publication Trends Analysis of his 2021-2024 publications reveals a concentrated focus on energy materials, particularly proton-exchange membranes for hydrogen fuel cells (accounting for 40% of recent output), biomass conversion processes, and sustainable nanocomposites. These works demonstrate methodological diversity spanning kinetic modeling, composite fabrication, and advanced stress analysis, primarily appearing in high-impact materials science and engineering journals. Academic Contributions Dr. Wu teaches core mechanical engineering courses including undergraduate Mechanics of Materials, Machine Design, and Vehicle Dynamics, alongside graduate-level instruction in Advanced Mechanics of Materials, Fracture Mechanics, Polymer Nanocomposites, and Smart Materials. His office is located in Dolve Hall 206 at NDSU where he maintains active research supervision and departmental service.

• Plant Membrane Transport Biology
• P-type ATPases
• Plant Physiology
• +6 more

Michael Broberg Palmgren is a Professor in Plant Physiology at the Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen. His research focuses on biological pumps in plants, particularly P-type ATPases, and their roles in growth, nutrient uptake, stress tolerance, and signal transduction. He leads the Section for Transport Biology and has been instrumental in translating knowledge from model plants like Arabidopsis thaliana to crop species including barley and quinoa. His research interests include accelerating the domestication of orphan crops and wild plants for sustainable agriculture, perennial wheatgrass development, quinoa breeding for improved drought and salinity tolerance, and investigating why plants lack sodium pumps and whether they would benefit from having them. His work addresses urgent agricultural challenges including reducing fertilizer and water use while preserving natural ecosystems. His recent publications (2024-2025) demonstrate continued research activity across plant membrane biology, crop domestication, and sustainable agriculture. These works explore chloroplast transport mechanisms, in vitro plant transformation techniques, gene family identification methods, calcium pump regulation, lipid flippase functions, and innovative approaches to quinoa improvement through saponin biosynthesis control. 2017 Scandinavian Plant Physiology Society (SPPS) Award 2016 Communicator of the Year, University of Copenhagen 2016 Knight of the Order of Dannebrog 2012 Best Teacher of the Year, Faculty of Life Sciences 2009 Elected member of the Academy for Technical Sciences, Denmark 2008 Elected member of Faculty of 1000 2005 Lifelong right to inhabit the Knud Sand Honorary Residence 2000 Elected member of the Royal Danish Academy of Sciences and Letters Professor Palmgren has supervised over 22 master's students and 22 PhD students throughout his career, with more than half of these supervisions occurring since 2006. He has served as opponent at over 10 PhD examinations outside the University of Copenhagen. His research is supported by major grants including the Novo Nordisk Foundation project 'NovoCrops' (2020-2026), Carlsberg Foundation's 'RaisingQuinoa' (2019-2024), and Innovation Fund Denmark's 'LESSISMORE' (2017-2020). He maintains an active presence in the scientific community through his leadership of the TRAP research group (http://www.traplabs.dk), editorial roles including Co-editor for The Plant Cell, and extensive public outreach with over 57 media appearances since 2014 discussing plant biology in Danish and international media.

• Molecular Biology
• Biochemistry
• Structural Biology
• +3 more

Johan Gotthardt Olsen serves as Assistant Professor and Guest Researcher in the Department of Biology within the Faculty of Science at the University of Copenhagen. His research focuses on the structural and dynamic properties of proteins, particularly intrinsically disordered systems and their biological functions. His primary research interests center on protein conformational dynamics, molecular recognition mechanisms, and the biophysical principles governing intrinsically disordered proteins. Olsen investigates how structural transitions in proteins regulate cellular processes like DNA replication, signal transduction, and enzyme activation, employing techniques spanning NMR spectroscopy, computational modeling, and biophysical characterization. Analysis of his recent publications (2021-2025) reveals a consistent research trajectory examining protein disorder-order transitions, with particular emphasis on molecular recognition in DNA-protein interactions and enzyme regulation. His work frequently combines experimental and computational approaches, resulting in publications in high-impact journals including Nature, Journal of the American Chemical Society, and Nucleic Acids Research. Olsen maintains active collaborations with multiple research groups, particularly with Professor Birthe B. Kragelund's team, as evidenced by co-authorship patterns across his publications. His research group participates in interdisciplinary projects bridging biochemistry, biophysics, and molecular biology, focusing on fundamental mechanisms with potential implications for drug discovery and disease understanding.

• Bacterial Genetics
• Chromosome Replication
• Antimicrobial Peptides
• +3 more

Godefroid Charbon is an Associate Professor in the Department of Biology at the University of Copenhagen, specializing in Functional Genomics. His research primarily focuses on bacterial chromosome replication mechanisms, antimicrobial resistance, and developing novel peptide-based antimicrobial strategies that minimize resistance development. Based at Ole Maaløes Vej 5 in Copenhagen, he maintains an active research program with extensive collaboration networks. Dr. Charbon's research centers on the molecular mechanisms of bacterial chromosome replication, particularly in Escherichia coli and Staphylococcus aureus . His work investigates the DnaA protein's critical role in replication initiation, cell cycle control, and how bacteria regulate DNA synthesis. A significant portion of his research focuses on developing peptide-nucleic acid conjugates that target essential replication proteins, creating antimicrobial approaches with reduced resistance potential. His functional genomics work examines bacterial responses to replication stress and antimicrobial challenges, with implications for understanding fundamental bacterial physiology and developing next-generation therapeutics. Analysis of Dr. Charbon's publication record reveals a consistent focus on bacterial replication mechanisms and antimicrobial development over the past five years. His research demonstrates expertise in molecular genetics, bacterial physiology, and antimicrobial discovery, with particular emphasis on overcoming antibiotic resistance mechanisms. The work spans from fundamental studies of replication initiation to applied research on novel antimicrobial compounds, showing strong translational potential. His frequent collaborations with Løbner-Olesen and others highlight interdisciplinary approaches combining molecular biology, genetics, and pharmaceutical sciences to address complex challenges in bacterial pathogenesis. Dr. Charbon maintains active research collaborations across multiple institutions, as evidenced by his extensive publication record totaling 35 research outputs. His work has generated significant academic interest, with multiple publications appearing in high-impact journals and receiving attention across academic platforms including Mendeley, X (Twitter), and Bluesky. His research program demonstrates strong continuity with publications spanning from 2021 through 2025, indicating an active and productive academic career trajectory at the University of Copenhagen.

Thomas Günther-PomorskiView profile

Professor

• Membrane Protein Biophysics
• Lipid Transport Mechanisms
• P-type ATPases
• +4 more

Thomas Günther-Pomorski serves as Full Professor at Ruhr-University Bochum and holds a part-time position at the University of Copenhagen's Department of Plant and Environmental Sciences (Section for Transport Biology). His research bridges plant biology and membrane biophysics, focusing on molecular mechanisms of lipid transport. His primary research interests include: Biophysical characterization of membrane proteins Function and dynamics of P4 ATPases in vesicular transport Molecular analysis of P-type ATPases ABC protein roles in sterol transport Plant plasma membrane H⁺-ATPase mechanisms Recent publications (2023-2025) demonstrate advanced methodologies including single-vesicle analysis , fluorescence-based flippase assays , and giant unilamellar vesicle reconstitution . Key trends show increasing focus on lipid-protein interactions , membrane asymmetry , and quantitative sterol analysis with applications in cellular trafficking and plant physiology. Professional activities include organizing the 9th Yeast Lipid Conference (2009) and presenting on lipid pump mechanisms at international venues. His ORCID profile (0000-0002-4889-0829) documents extensive collaborative work across membrane biology disciplines.

Mark Christian LeakeView profile

Professor

• Biological Physics
• Single-molecule Biophysics
• Biophotonics
• +7 more

Mark Christian Leake is the Anniversary Chair of Biological Physics at the University of York, holding a joint appointment between the Physics and Biology Departments within the School of Physics, Engineering and Technology. He serves as Coordinator of the Physics of Life Group, which hosts approximately 50 cross-disciplinary researchers, and previously served as Director and Founder of the Biological Physical Sciences Institute from 2013-2019. Leake is also an active Visiting Professor at Oxford University's Department of Physics since 2013. Leake's research focuses on developing innovative biophysical instrumentation and applying these tools to address fundamental biological questions at the single-molecule level. His work spans several key areas: DNA gyrase mechanisms as an antibiotic target; DNA replication and repair processes; signal transduction and gene regulation in yeast; DNA topology and protein interactions; and liquid-liquid phase separation in cells. His laboratory has constructed a wide range of custom light microscopy instruments including TIRF microscopy, smFRET, optical and magnetic tweezers, and rapid millisecond single-molecule imaging systems. Analysis of his recent publications reveals a strong emphasis on liquid-liquid phase separation phenomena across biological systems, DNA mechanics and replication processes, and the development of novel biophysical techniques to study these phenomena in vivo. His work increasingly bridges physics, biology, and medicine, with applications in antibiotic development, cancer research, and photosynthesis optimization. Rosalind Franklin Medal, Institute of Physics (2020) Young Investigator Award, British Biophysical Society (2010) Royal Society University Research Fellowship (2007) Daiwa Adrian Anglo-Japanese Prize (2007) Elected Fellow of the Institute of Physics, Royal Microscopical Society, and Royal Society of Biology Leake has secured significant research funding including EPSRC and BBSRC grants for projects such as 'The Biophysics of Mesoscale, Reversible, Biomolecular Assemblies' and 'How bacteria replicate their DNA in spite of barriers, one molecule at a time.' He actively mentors students and early-career researchers, having published a guide titled 'Surviving Early Career Research and Beyond in Biophysics/Biological Physics.' Leake leads the Physics of Life Group, which functions as a Discovery Research Theme fostering interdisciplinary collaboration between physical and life scientists at York.

Andrew EllisdonView profile

Associate Professor

• Cancer
• Structural Biology
• Crystallography
• +3 more

Assoc. Prof. Andrew Ellisdon is an Associate Professor (Research) at Monash University’s Monash Biomedicine Discovery Institute (BDI), leading the Structural Biology of Signalling and Cancer Laboratory. He holds a VCA Mid-Career Fellowship and focuses on structural biology, particularly elucidating molecular mechanisms of oncogenes and tumor suppressors using cryo-electron microscopy, crystallography, and biochemistry. His work aims to advance drug development for cancers, including neurofibromatosis-linked tumors. Ellisdon leads a team of postdocs, research assistants, and PhD students, and has secured significant grants, including NHMRC equipment funding. Research interests include metastatic signaling pathways, protein complexes in cancer, and therapeutic target discovery. Recent projects involve structural analysis of neurofibromin and P-Rex1, and developing IL-37-based anti-inflammatory therapeutics. Ellisdon has been recognized with the 2018 Vice-Chancellor’s Award for Research Enterprise. His collaborations span structural biology, drug discovery, and translational medicine, contributing to UN Sustainable Development Goals related to health and innovation.

• Structural Biology
• Protein Kinase Signaling
• Receptor Tyrosine Kinases
• +4 more

Yuko Tsutsui is a Research Scientist in the Department of Pharmacology at Yale School of Medicine. Her research focuses on structural biology, protein kinase signaling, and molecular mechanisms of enzyme inhibition. She employs advanced techniques like hydrogen-deuterium exchange mass spectrometry (HDX-MS) to study protein dynamics and conformational changes. Key areas of investigation include receptor tyrosine kinases, GPCR interactions, and drug resistance mechanisms in cancer-related kinases. Dr. Tsutsui has contributed to understanding EGFR mutations' inhibitor sensitivity and structural basis for ligand recognition in anaplastic lymphoma kinase. Her work spans from fundamental protein dynamics studies to translational insights into disease pathways. Research Highlights: Structural basis for dROS1-BOSS receptor interactions in developmental signaling Allostery mechanisms in BAK1 immune co-receptor activation Epigenetic regulation of E. coli lipopolysaccharide synthesis Structural insights into EGFR exon 19 mutation drug resistance Longstanding studies on serpin protein folding and stability Publications span structural biology, biochemistry, and molecular pharmacology, with contributions to Nature, Nature Communications, and PNAS. She collaborates with leading groups in pharmacology and structural biology at Yale and internationally.

• Cell Biology
• Neuroscience
• Membrane Biology
• +3 more

Jeff Coleman, PhD, is a Researcher in the Department of Cell Biology at Yale School of Medicine, affiliated with the Rothman Lab. His research focuses on molecular mechanisms of synaptic vesicle release, membrane protein organization, and SNARE complex assembly. He holds a BA from the University of California, Berkeley (1989) and a PhD from the University of Melbourne (2002). Coleman collaborates extensively with researchers like Shyam Krishnakumar and Frederic Pincet, investigating calcium signaling, membrane fusion, and protein oligomerization. His work employs advanced techniques such as single-molecule imaging and native mass spectrometry to study synaptic processes. Recent studies include roles of diacylglycerol in synaptic vesicle priming and the structural dynamics of synaptotagmin oligomers. Education: PhD, University of Melbourne (2002); BA, UC Berkeley (1989) Key Research Themes: SNARE complex assembly, membrane protein oligomerization, calcium-dependent exocytosis, synaptic vesicle trafficking Publications highlight his contributions to understanding molecular determinants of complexin function and the development of novel platforms like the 'plasma membrane-on-a-chip' for single-molecule studies. Coleman’s work bridges biochemistry and neuroscience, with implications for neurodegenerative diseases and cellular signaling.

Tikvah Katheryn HayesView profile

Assistant Professor

• Oncogene Dependency
• Signal Transduction
• Therapeutic Strategies in Cancer
• +5 more

Tikvah Katheryn Hayes is an Assistant Professor in the Department of Molecular and Medical Pharmacology at the University of California Los Angeles (UCLA) School of Medicine. Her research focuses on oncogene dependency, signal transduction, and therapeutic strategies for cancers, particularly pancreatic and lung tumors. She leads the Hayes Lab, which investigates molecular mechanisms of cancer progression and drug resistance. 2024: Author Correction on EGFR extracellular domain mutants and TKI sensitivity 2023: Study on lung cancer evolution in Nature 2021: ERK-autophagy combination therapy for pancreatic cancer in Cell Reports 2020: Research on KRAS epigenetics and RAS protein interactions 2019: NRAS-mutant melanoma drug resistance landscape 2015: ERK inhibition effects on KRAS pancreatic cancer Her work spans DNA repair pathways, RAS biology, and genome instability, with collaborations across institutions like UCSD and USC. Key methodologies include functional genomics, protein interaction analysis, and preclinical cancer modeling.

Raphael LedermannView profile

Researcher

• Microbiology
• Plant-Microbe Interactions
• Symbiosis
• +3 more

Dr. Raphael Ledermann is a Post-Doc Researcher at the University of Oxford, affiliated with the Rhizosphere Group. His research focuses on the molecular mechanisms underlying Rhizobium-legume symbioses, particularly how bacteria and plants coordinate metabolism and physiology to establish mutualistic nitrogen-fixation interactions. His work addresses symbiosis adaptation, environmental stress responses, and microbial community dynamics in plant-associated niches. Contact details include his email raphael.ledermann@biology.ox.ac.uk and professional profiles on ResearchGate (Orchid ID: B-4301-2018). His research portfolio spans microbiology, plant biology, and systems approaches to understand symbiotic relationships and bacterial adaptation strategies. Key research themes include nitrogen fixation mechanisms, bacterial stress responses (osmotic/salt), microbial community assembly, and symbiotic signaling pathways. His recent findings highlight roles of metabolic enzymes, hopanoids, and chemical chaperones in enabling symbiotic success under environmental challenges. Publications (2014-2025) reflect interdisciplinary approaches combining molecular genetics, biochemistry, and systems biology to elucidate symbiosis at cellular and ecological scales. While no awards are explicitly listed, his work contributes foundational insights to legume-microbe symbiosis research.