Find Academic Supervisors

• Bioinformatics
• Machine Learning
• Deep Learning
• +5 more

Ole Winther is Professor in High dimensional biological data analysis/Machine learning at the Department of Biology, University of Copenhagen and Professor in Data science and complexity at DTU Compute, Technical University of Denmark. He serves as CRO and co-founder of raffle.ai, CTO and co-founder of FindZebra, Head of ELLIS Unit Copenhagen, and co-PI of the Machine Learning for Life Science Center. His research spans Bioinformatics , Machine Learning , and AI for Science , focusing on applying deep learning to biological sequence analysis, latent variable models, and medical NLP. Winther's work develops predictive and generative models for bioinformatics, with significant contributions to protein localization tools (SignalP, DeepLoc, DeepTMHMM), single-cell genomics, and novel deep learning architectures like variational autoencoders and diffusion models. Analysis of Winther's recent publications (2023-2025) reveals a strong trend toward integrating protein language models with traditional bioinformatics approaches and applying diffusion models to scientific problems. His work bridges theoretical machine learning advancements with practical applications in biology and medicine, particularly in protein sequence analysis, medical search engines, and scientific simulation acceleration. Winther currently supervises a diverse research group including Panagiotis Antoniadis, Rachael M. DeVries, Jun Wang, Beatrix M. G. Nielsen, Felix G. Teufel, Irene R. Rodriguez, Anders Christensen, and Christopher Heje Grønbech. His former students have established successful careers at institutions including Google, Apple, and various startups, with notable alumni like Casper Sønderby (Google Brain) and Søren Sønderby (Apple). He leads significant research initiatives including the ELLIS Unit Copenhagen and the Machine Learning for Life Science Center, while maintaining active industry partnerships through his co-founded companies raffle.ai (enterprise search using NLP) and FindZebra (search engine for rare diseases). His teaching includes Deep Learning courses at both DTU (02456) and University of Copenhagen (NDAK24002U).

Thomas WalzView profile

Professor

• Membrane Biology
• Structural Biology
• Cryo-electron Microscopy
• +5 more

Thomas Walz, PhD, is a Professor at The Rockefeller University and Head of the Laboratory of Molecular Electron Microscopy. Previously, he held positions as Assistant, Associate, and Professor at Harvard Medical School (1999–2015) and was an Investigator at the Howard Hughes Medical Institute (2008–2015). He earned his PhD and BS in biophysics from the University of Basel, Switzerland, and completed postdoctoral research at the University of Sheffield. Walz completed his education at the Biozentrum, University of Basel, Switzerland, where he received his Diploma in Biophysics (1992) and PhD in Biophysics (1996). He furthered his training as a postdoctoral researcher at the University of Sheffield (1996–1999). His research focuses on understanding membrane-related processes and the structural biology of membrane proteins in lipid environments. Utilizing cryo-electron microscopy and nanodisc technology, he investigates how lipid bilayers influence membrane protein structure and function. Key areas include mechanosensitive channels, T-cell receptor dynamics, and telomere maintenance mechanisms. Collaborations with the de Lange lab explore the CST-Polα/primase complex's role in telomere regulation. Walz has been recognized with the Genzyme Award for Outstanding Achievement in Biomedical Sciences (2004) and continues to contribute to advancements in structural biology and membrane protein research. While specific student advisees are not listed, Walz actively mentors through his roles in the David Rockefeller Graduate Program and Tri-Institutional programs. His research is supported by grants and institutional funding, though specific grants are not detailed here. He directs the Laboratory of Molecular Electron Microscopy at Rockefeller, a hub for innovative structural biology and membrane protein studies. The lab collaborates widely, integrating cryo-EM with electrophysiology and molecular dynamics simulations.

Sriram SubramaniamView profile

Professor

• cryo-electron microscopy
• structural biology
• drug-design
• +4 more

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Weiping TangView profile

Professor

• Targeted Protein Degradation
• PROTACs
• Medicinal Chemistry
• +5 more

Weiping Tang is a Professor of Pharmaceutical Sciences and Chemistry at the University of Wisconsin-Madison, holding the Janis Apinis Professorship in the School of Pharmacy and the Vilas Distinguished Achievement Professorship. He also serves as Director of the Medicinal Chemistry Center at the School of Pharmacy and maintains a faculty appointment with the Department of Chemistry in the College of Letters and Science. Janis Apinis Professor of Pharmaceutical Sciences Vilas Distinguished Achievement Professor Director of Medicinal Chemistry Center Faculty Appointment with Department of Chemistry Dr. Tang received his B.S. in Chemistry from Peking University in 1997, M.S. in Chemistry from New York University in 1999, Ph.D. in Organic Chemistry from Stanford University in 2005, and completed a postdoctoral fellowship in Medicinal Chemistry, Chemical Biology and Drug Discovery at Harvard University in 2007. Dr. Tang's research program focuses on drug discovery for cancer, infectious diseases, and neurodegenerative disorders through three interconnected areas: Organic Synthesis (advancing glycoscience through novel carbohydrate synthesis technologies), Medicinal Chemistry (developing small molecules that selectively remove disease-associated proteins), and Chemical Biology (dissecting biological pathways using novel small molecule probes). His group operates as an interdisciplinary team where chemists and biologists collaborate closely on drug discovery projects, with particular emphasis on developing novel degraders for disease-causing proteins. Analysis of Dr. Tang's publication record reveals a significant shift toward targeted protein degradation technologies, particularly PROTACs and molecular glues, while maintaining strong foundations in carbohydrate chemistry. His most impactful recent work includes developing degraders for extracellular and membrane proteins (previously considered 'undruggable'), creating rapid synthesis platforms like Rapid-TAC and Rapid-Glue, and advancing understanding of ternary complex formation for novel PROTAC design. His research spans both chemical methodology development and therapeutic applications across multiple disease areas. Vilas Distinguished Achievement Professorship Janis Apinis Professorship Numerous high-impact publications in leading chemistry and pharmacology journals Editor's pick and hot paper designations for significant contributions Dr. Tang mentors a diverse team of graduate students, postdoctoral fellows, and staff scientists with expertise spanning synthetic chemistry, medicinal chemistry, carbohydrate chemistry, computational chemistry, biochemistry, and cell biology. His group has developed innovative platforms for the rapid synthesis of protein degraders and has made significant contributions to understanding the mechanisms of action for these novel therapeutics. Current research includes developing selective degraders for cancer targets like RIPK1, BRD4, and CARM1, as well as advancing delivery systems for clinical translation. The Tang Research Group maintains state-of-the-art facilities within the School of Pharmacy at UW-Madison, equipped for comprehensive chemical synthesis, compound characterization, and biological evaluation. The group actively collaborates with researchers across campus and with industry partners to advance discoveries toward clinical applications, with particular focus on cancer therapeutics and protein degradation technologies.

Vadim CherezovView profile

Professor

• Membrane Protein Structure and Function
• G Protein-Coupled Receptors (GPCRs)
• Lipid-Protein Interactions
• +3 more

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

Steven G. ClarkeView profile

Professor

• Biochemistry
• Systems Biology
• Biological Regulation
• +8 more

Dr. Steven G. Clarke is a Distinguished Professor at UCLA Department of Chemistry & Biochemistry and director of research at the Molecular Biology Institute . His work bridges protein chemistry , methylation biology , and aging research through studies of spontaneous protein damage and its repair mechanisms. Education: BA in Chemistry and Zoology, Pomona College (magna cum laude, Phi Beta Kappa) PhD in Biochemistry and Molecular Biology, Harvard University (NSF Fellow) Postdoctoral Fellowship at UC Berkeley (Miller Fellow) Dr. Clarke's research focuses on protein isoaspartyl repair via PCMT1/PIMT enzymes , ribosomal protein methylation in Saccharomyces cerevisiae , and PRMT family characterization including PRMT7 and PRMT9. His lab combines biochemical assays , genetic models , and structural analysis to investigate aging mechanisms and disease implications. Recent publications highlight: COQ5 structure-function analysis in coenzyme Q biosynthesis PCMTD1 ubiquitin ligase interactions PRMT7 substrate specificity in histone H2B Protein isoaspartyl impacts on T cell function in lupus Novel PRMT inhibitors for cancer therapy Methionine addiction in osteosarcoma malignancy Major scientific awards: American Chemical Society Ralph F. Hirschmann Award in Peptide Chemistry NIH MERIT Award Ellison Medical Foundation Senior Scholar Award William C. Rose Award, ASBMB UCLA Distinguished Teaching Award (Eby Award winner) Current lab members include PhD candidates Eric Pang (UCSB) and Sining "Cindy" Wang (UCLA), while undergraduates Celeste Medina-Seymoure , Elizabeth Oroudjeva , Olivia Pacheco , and Jasmine Winter contribute to ongoing proteostasis studies. Collaborations with Profs. Jose Rodriguez and Catherine Clarke demonstrate interdisciplinary research approaches.

Ralph H. ColbyView profile

Professor

• Polymer Physics
• Rheology
• Ionomers
• +5 more

Ralph H. Colby serves as Professor of Materials Science and Engineering and Chemical Engineering at Pennsylvania State University's College of Earth and Mineral Sciences, holding the Corning Faculty Fellowship. His research focuses on molecular-level dynamics in complex fluids, particularly polymers, ionomers, and liquid crystalline systems. With over 130 publications and authorship of the textbook Polymer Physics (2003), he directs an active research program examining structure-property relationships in soft matter. B.S. in Materials Science and Engineering, Cornell University (1979) M.S. in Chemical Engineering, Northwestern University (1983) Ph.D. in Chemical Engineering, Northwestern University (1985) Professor Colby's research spans polymer physics, rheology, and materials for energy applications. His group employs mechanical rheology, dielectric spectroscopy, and scattering techniques to investigate ion transport in single-ion conductors for batteries, dynamics of glass-forming liquids, and self-assembly in polyelectrolyte systems. Current work emphasizes structure-property relationships in ionomers, liquid crystalline polymers, and branched architectures. Analysis of recent publications reveals consistent focus on ionomer membranes for energy applications, processing-structure relationships in advanced polymers, and fundamental dynamics of complex fluids. Key trends include increasing integration of computational modeling with experimental characterization, expansion into sustainable materials processing, and growing emphasis on applications in battery technology and biomedical materials. Penn State Faculty Scholar Medal for Outstanding Achievement (2022) Bingham Medal, Society of Rheology (2012) American Chemical Society Fellowship Corning Faculty Fellowship in Materials Science and Engineering Professor Colby leads multiple federally funded projects including NSF's 'Fundamental Studies of Flow-Induced Polymer Crystallization' and DOE's 'Conduction mechanisms and structure of ionomeric single-ion conductors'. His group maintains strong industry partnerships with Corning Incorporated and participates in interdisciplinary initiatives like the Penn State Intercollege Graduate Degree Program in Materials Science and Engineering. Current research includes collaborations on breast cancer adherence interventions in Rwanda and conjugated polymer development for flexible electronics. The Colby Research Group operates specialized facilities for rheological characterization, dielectric spectroscopy, and X-ray scattering at Penn State's Materials Research Institute. The team maintains active collaborations with national laboratories and international research groups, focusing on translating fundamental polymer physics discoveries into practical applications for energy storage and advanced manufacturing.

Benjamin MachtaView profile

Assistant Professor

• Biophysics
• Condensed Matter Physics
• Statistical Physics
• +3 more

Benjamin Machta is an Assistant Professor of Physics at Yale University, affiliated with the Department of Physics and the QBio Institute. He holds a BS from Brown University and a PhD from Cornell University, followed by a postdoctoral fellowship at Princeton University. His research focuses on applying theoretical physics to understand biological systems, particularly leveraging statistical physics and information theory to study biological membranes near critical points and the energetic constraints of biological signaling. Education: BS in Physics (Brown University), PhD in Physics (Cornell University), Postdoc at Princeton University (Lewis-Sigler Theory Fellow). Research Interests include: membrane criticality, phase transitions in biological systems, information-theoretic limits in organism function, and energy dissipation in biological processes. His work often bridges theoretical models with experimental data, such as collaborations with Sarah Veatch’s lab on membrane phase behavior. Publications highlight themes like membrane criticality, protein phase separation, and energy constraints in signaling. His group’s current projects explore cochlear mechanics, thermodynamic control in biological systems, and the role of criticality in sensory systems. Awards: 2019 Simons Investigator Award. Lab Affiliations: QBio Institute and Department of Physics at Yale, located in YSB-C164. Group members include postdocs Isabella Graf and Michael Abbott, and graduate students Asheesh Momi, Mason Rouches, and others.

• Virology
• Molecular Biology
• Genomics
• +6 more

James Van Etten is the William Allington Distinguished Professor of Plant Pathology at the University of Nebraska-Lincoln, affiliated with the School of Biological Sciences and Nebraska Center for Virology. His research focuses on chloroviruses—large dsDNA viruses infecting Chlorella-like algae—with emphasis on DNA replication, restriction systems, and membrane transport proteins. Key research themes include: Viral DNA modification systems Host-virus interactions Structural virology Evolution of organellar genomes Recent work analyzed: SMRT sequencing of viral methylation patterns Chlorovirus cryopreservation methods Potassium channel biophysics Host chemical signaling mechanisms Lab webpage: vanettenlab.unl.edu

Waldemar KolanusView profile

Professor

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +4 more

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

Christoph SchmidtView profile

Professor

• Biophysics
• Cell Mechanics
• Microrheology
• +5 more

Christoph F. Schmidt is the Hertha Sponer Distinguished Professor of Physics at Duke University with cross-appointments in the Thomas Lord Department of Mechanical Engineering and Materials Science, Biology, and Biomedical Engineering. He serves as Co-Director of the Duke Materials Initiative and leads an active research program at the intersection of physics and biology. His educational background includes a D.R. from the Technical University of Munich (Germany) in 1988. Schmidt has established himself as a leading researcher in biophysics through decades of innovative work. Professor Schmidt's research spans multiple scales of biological organization, from single molecules to whole organisms. His lab investigates cellular mechanics using advanced techniques including optical trapping, atomic force microscopy, and microrheology. A significant innovation from his group involves single-walled carbon nanotubes for high-bandwidth intracellular tracking. Current research focuses on cardiomyocyte mechanics, Drosophila tissue dynamics, and computational analysis of complex biological systems. His work on motor proteins like Eg5 and ncd has provided fundamental insights into cellular division mechanics. His recent publications (2021-2025) demonstrate increasing integration of computational approaches with experimental biophysics, particularly in analyzing cardiac tissue mechanics and Drosophila sensory systems. The work shows progression from fundamental biophysical measurements toward applications in understanding disease mechanisms and biological function. Professor Schmidt teaches several courses including PHYSICS 995 (Graduate Training Internship), PHYSICS 493 (Research Independent Study), PHYSICS 415 (Biophysics II), PHYSICS 174 (Introduction to Frontiers of Biophysics), and BIOLOGY 425 (Biophysics II). He has successfully mentored numerous graduate students to completion, including recent PhD graduates Dr. Mingru Li and Dr. Xiaoxuan Jian. The Schmidt Lab, part of Duke's Physics Department and the Duke Soft Matter Center, maintains state-of-the-art equipment for optical trapping, atomic force microscopy, and advanced light microscopy. The lab participates in the Triangle Soft Matter Workshop, fostering collaborations with researchers from Duke, UNC Chapel Hill, and NC State University. Current research directions include mechanical responses of suspended cells, tracking non-equilibrium cellular fluctuations, nuclear mechanics, and bacterial membrane mechanics under turgor pressure.

Mark WallaceView profile

Professor

• Membrane Biology
• Biophysics
• Optical Microscopy
• +3 more

Mark Wallace is a Professor of Chemistry at King's College London, affiliated with the Department of Chemistry and the Faculty of Natural, Mathematical & Engineering Sciences. He holds a Royal Society University Research Fellowship (2005–2016) and has been a lecturer at Oxford University before joining King's in 2016. His research focuses on membrane protein function and artificial membrane mimics, combining optical microscopy and nanotechnology. He earned a PhD from the University of Cambridge (2002) and postdoctoral training at Stanford University and the National Institute for Medical Research. Key research interests include membrane protein dynamics, lipid bilayer engineering, and single-molecule imaging. He has pioneered techniques like droplet interface bilayers and interferometric scattering microscopy. His work has led to patents and applications in molecular sensing and medical research. Awards include the 2002 Gregorio Weber Prize and the 2015 RSC Norman Heatley Award. He is actively involved in public outreach, including video podcasts and educational competitions. Recent publications emphasize artificial ion channels, nanoparticle formation monitoring, and mitochondrial protein dynamics. His lab collaborates with institutions like the London Centre for Nanotechnology and the Rosalind Franklin Institute. Over 30 students and researchers have been mentored, with active grants from EPSRC, Wellcome Trust, and BBSRC.

• Biophysics
• Membrane Proteins
• Structural Biology
• +3 more

Dr. Lukas Frey is a Researcher at ETH Zurich, affiliated with the Chair of Physical Chemistry and the Institute of Molecular Physical Sciences (IMPS). His work focuses on biophysical studies of membrane proteins, lipid dynamics, and protein aggregation mechanisms. Key research areas include structural biology of ion channels, NMR spectroscopy of membrane proteins in nanodiscs, and the role of lipid environments in modulating protein dynamics. Frey employs advanced techniques like mass photometry and solid-state NMR to investigate molecular mechanisms in biological systems. His recent studies address amyloid fibril formation, pH-dependent α-synuclein polymorphism, and cholesterol-mediated modulation of membrane protein behavior. Based at the HCI F 228 facility in Zurich, Frey collaborates on projects involving lipid bilayer environments, ion channel function, and the structural basis of protein aggregation. His email is lukas.frey@phys.chem.ethz.ch, and he holds an ORCID identifier 0000-0002-1052-1104. Research contributions span from fundamental biophysical insights to methodological advancements in membrane protein analysis.

Yi ShenView profile

Senior Lecturer

• Protein Biophysics
• Soft Materials
• Microfluidics
• +5 more

Dr. Yi Shen is a Senior Lecturer at the School of Chemical and Biomolecular Engineering, The University of Sydney, and Chair of RACI Women in Chemistry. She is also affiliated with multiple research institutes including Sydney Institute of Agriculture, Sydney Southeast Asia Centre, The Centre for Drug Discovery Innovation, and The University of Sydney Nano Institute. PhD in Soft Materials from ETH Zurich Postdoctoral research at University of Cambridge and Harvard University Her research focuses on protein phase behavior and functional biomaterials development, utilizing soft matter approaches and microfluidic techniques to address challenges in neurodegenerative diseases, sustainable materials, and biomedical engineering. She has published extensively in top journals like Nature Nanotechnology and PNAS, with a particular emphasis on: Protein liquid-liquid phase separation mechanisms Biomaterials from protein nanofibrils Microfluidic manipulation of biological systems Biodegradable bioplastics development Shear force effects on biomolecular systems Pathological protein aggregation dynamics Key scientific achievements include: 2022 ARC DECRA Fellowship 2022 Sydney Nano Frontier award 2018 ETH Zurich Spark Award (for Fe delivery system invention) 2012 Princeton Grand Challenges Program 2 patents pending 2 Nature Nanotechnology cover articles As an educator, she coordinates CHNG2802 Chemical Engineering Modelling and Analysis, co-teaches CHNG3804 Biochemical Engineering and CHNG5605 Bio-products: Laboratory to Marketplace, and guest lectures across biomedical and nanotechnology programs. Her lab actively collaborates with institutions in Switzerland (ETH Zurich), UK (Cambridge), and US (Harvard, Princeton), focusing on transforming biomolecular understanding into real-world applications in health, industry, and environmental sustainability.

Aditi DasView profile

Professor

• Biochemistry and Chemical biology of Lipids
• Mechanism of Membrane proteins in Nanodiscs
• Enzymology of metalloproteins
• +5 more

Aditi Das is a Full Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology, College of Sciences. She leads the Das Laboratory, which focuses on the biochemistry and chemical biology of lipids, particularly studying cytochrome P450 enzymes and their role in lipid metabolism, endocannabinoid systems, and inflammatory pathways. Her educational background includes: B.Sc. in Chemistry from St. Stephen's College M.Sc. in Chemistry from Indian Institute of Technology, Kanpur (I.I.T) Ph.D. in Chemistry from Princeton University Postdoctoral research at Northwestern University (NSF-NSEC fellow) and Beckman Institute for Advanced Science and Technology, University of Illinois UC Professor Das's research interests center around understanding the physiological role of lipids in sustaining homeostasis and their implications in disease states such as neurodegenerative disorders, cancer, and cardiovascular diseases. Her laboratory specializes in: Enzymology of cytochrome P450s, particularly CYP2J2 epoxygenase Metabolism of ω-3 and ω-6 fatty acids and their derivatives Minor cannabinoid metabolism by cytochrome P450 enzymes Discovery of novel anti-inflammatory lipid metabolites and endocannabinoids Mechanistic studies of membrane proteins using nanodisc technology Her work bridges biochemistry, chemical biology, and pharmacology to uncover novel therapeutic targets related to lipid signaling pathways. Analysis of Professor Das's recent publications (2023-2025) reveals a strong focus on cannabinoid metabolism by cytochrome P450 enzymes, with particular emphasis on how these metabolic processes generate bioactive compounds that interact with the endocannabinoid system. Her research increasingly explores the therapeutic potential of omega-3 derived endocannabinoid epoxides in inflammatory and neurodegenerative conditions. The use of nanodisc technology for studying membrane proteins in near-native environments remains a consistent methodological thread throughout her work, enabling detailed mechanistic insights into enzyme function. Professor Das has received numerous prestigious awards recognizing her research excellence and teaching: 2024 NIH Outstanding Researcher Award (MIRA R35) for established investigators 2024 Vasser Woolley Faculty Fellowship 2023 Plenary Lecture at the International Society of the Study of Xenobiotics (ISSX) 2021 E.L.R. Stokstad Award 2019-2021 List of Teachers Ranked as Excellent 2019 Eicosanoid Research Foundation Young Investigator Award 2019 Zoetis Research Excellence Award 2019 Mary Swartz Rose Young Investigator Award 2015 National Scientist Development Award from the American Heart Association 2022 El Sohly Award from the American Chemical Society Professor Das actively mentors a diverse group of students and postdoctoral researchers, with several former lab members now holding faculty positions or working at prestigious institutions. Her laboratory has secured significant funding from NIH, NSF, and other sources to support research on lipid metabolism, cannabinoid pharmacology, and membrane protein biochemistry. Notable grants include an NIH R35 Outstanding Investigator Award (MIRA), an NIH R21 grant from NIDA, and multiple collaborative grants with other research groups. The Das Laboratory operates within the Petit Institute of Bioengineering and Biosciences (IBB) at Georgia Tech, utilizing state-of-the-art facilities for biochemical and biophysical studies. The lab specializes in nanodisc technology to study membrane proteins in near-native environments, with particular expertise in cytochrome P450 enzymes and their interactions with lipid substrates. Recent work has expanded into collaborative projects involving lipidomics, structural biology, and translational applications of lipid signaling research.