Matrix Analytic Methods Professors and Supervisors in Denmark

Christine ChuangView profile

Assistant Professor

University of CopenhagenDenmark

Christine Chuang is an Assistant Professor in the Department of Biomedical Sciences at the University of Copenhagen's Faculty of Health and Medical Sciences, where she leads research in the Inflammation, Metabolism and Oxidation (IMOX) group. Her work focuses on understanding how extracellular matrix (ECM) proteins in artery walls are damaged by inflammatory reactive oxidants during chronic inflammatory diseases like atherosclerosis. Dr. Chuang completed her academic training with a Bachelor (Hons) in Biotechnology from the University of New South Wales (UNSW), Australia, followed by a PhD investigating "Role of Perlecan in Cartilage Regeneration" at the Graduate School of Biomedical Engineering, UNSW. She then pursued postdoctoral research at the Heart Research Institute (HRI), University of Sydney, before joining the University of Copenhagen in 2014. Her research program centers on the critical role of extracellular matrix in cardiovascular health and disease. She investigates how oxidative damage to ECM components affects vascular cell function and contributes to atherosclerosis progression. Her work has particular relevance given that cardiovascular disease costs the EU approximately 169 billion Euros annually. Dr. Chuang currently leads four major research projects: (1) Investigating hypoxia effects on ECM generation and expression; (2) Characterizing inflammatory oxidant-modified ECM components and their cellular effects; (3) Studying MPO binding to ECM components; and (4) Evaluating selenium compounds as protective antioxidants. Her research employs advanced techniques including mass spectrometry peptide-mapping, cellular assays, and analysis of human atherosclerotic lesions. Analysis of her recent publications (2023-2025) reveals a strong focus on hypoxic conditions, oxidative modifications to ECM proteins, and their implications for vascular cell behavior. Her work spans biochemical analysis of matrix components, cellular responses to modified ECM, and potential therapeutic interventions targeting oxidative damage. Chairman of Danish Society for Matrix Biology (DSMB) Teaches Basal Human Biology and Mave, tarm og lever (Stomach, intestine and liver) Her collaborative research spans multiple institutions, with particular emphasis on proteomics approaches to understand protein modifications in cardiovascular disease contexts. Dr. Chuang's laboratory investigates both fundamental mechanisms of ECM damage and potential clinical applications of their findings, including novel antioxidant strategies and biomarker development for early detection of atherosclerosis.

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Kathrine Østerballe SkovView profile

Researcher

University of CopenhagenDenmark

Kathrine Østerballe Skov serves as a Postdoctoral Researcher at the Section of Forensic Chemistry within the Department of Forensic Medicine, University of Copenhagen's Faculty of Health and Medical Sciences. Her expertise centers on analytical chemistry applications in forensic toxicology, specifically targeting drug-facilitated sexual assault (DFSA) investigations through biological sample analysis. Her academic foundation includes a PhD in Forensic Chemistry from the University of Copenhagen (2020–2023), MSc in Molecular Nutrition & Food Technology from Aarhus University (2017–2019), and BSc in Global Nutrition and Health from VIA University College (2011–2015). This multidisciplinary background informs her methodological approach to toxicological analysis. Skov's research concentrates on optimizing analytical workflows for DFSA cases, with significant emphasis on enzymatic hydrolysis techniques to enhance drug detection in urine samples. Her current projects develop systematic toxicological analysis strategies that improve sensitivity and reliability in forensic evidence recovery, directly addressing challenges in identifying date-rape drugs and their metabolites. This work bridges biochemical innovation with practical forensic application. Analysis of her 2023–2024 publications reveals a cohesive research trajectory focused on Eastern Denmark case data (2015–2022), demonstrating methodological evolution from basic drug screening toward automated enzymatic hydrolysis protocols. Her work consistently targets benzodiazepines, GHB, and polydrug interactions within DFSA contexts, establishing new standards for forensic toxicology laboratories. Affiliated with the University of Copenhagen's Department of Forensic Medicine at Frederiksvej V's Vej 9-11, Copenhagen Ø, Skov operates within Denmark's primary forensic research infrastructure. Her section provides critical toxicological support for criminal investigations, with her enzymatic hydrolysis research directly influencing national forensic protocols for sexual assault evidence processing.

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Rebecca Louise MillerView profile

Associate Professor

University of CopenhagenDenmark

Rebecca Louise Miller is an Associate Professor in the Department of Cellular and Molecular Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences. She leads research in the Glycomics Program, focusing on glycosaminoglycan (GAG) biology and engineering, with laboratory facilities at Blegdamsvej 3 in Copenhagen. Dr. Miller's research centers on glycosaminoglycans, which are sulfated polysaccharides that play critical roles in the extracellular matrix. Her work specifically investigates the "sulfation code" of GAGs and how it relates to their diverse biological functions including cell migration, anticoagulation, angiogenesis, inflammation, and normal growth and development. By using genetic engineering approaches with KO/KI of genes in CHO cells, her lab produces cell-derived libraries displaying distinct heparin, heparan sulfate, chondroitin sulfate, and dermatan sulfate on cell surfaces. This innovative approach enables the dissection of structure-function relationships and the development of homogeneous GAG molecules with targeted therapeutic properties. Her recent publications demonstrate a strong interdisciplinary focus spanning glycobiology, analytical chemistry, cardiovascular biology, neuroscience, and infectious disease research. The articles reveal a consistent theme of developing and applying advanced methodologies—including mass spectrometry and single-molecule imaging—to characterize complex glycan structures and their interactions. Her work bridges fundamental science with translational applications, particularly in developing next-generation glycan-based therapeutics with defined structures rather than the heterogeneous animal-derived mixtures currently used clinically. Dr. Miller maintains an active laboratory that combines molecular biology, biochemistry, and analytical approaches to tackle the challenges of GAG complexity. Her research has significant implications for developing precision glycotherapeutics with specific biological activities (anti-coagulant, anti-inflammatory, or anti-viral) based on precisely engineered sulfation patterns, potentially revolutionizing treatment approaches for numerous conditions.

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Knud Erik Bach KnudsenView profile

Professor

Aarhus UniversityDenmark

Knud Erik Bach Knudsen is a Professor at the Department of Animal and Veterinary Sciences (ANIVET) at Aarhus University. His research focuses on the nutritional and health aspects of carbohydrates, phytochemicals, and their applications in animal and human nutrition, particularly in mono-gastric species. He specializes in developing analytical methods for carbohydrates in feeds and digestive materials, and investigates their role in preventing digestive disorders in pigs. Key projects include studying fiber’s impact on methane production in pigs, optimizing feed composition using near-infrared spectroscopy, and exploring macroalgae as potential ruminant feeds. He collaborates on initiatives like FIBERMÆLK to reduce livestock’s environmental footprint and Born2Live to improve piglet survival rates. His scientific contributions span peer-reviewed journals such as Nutrients and Animal Feed Science and Technology, with a focus on digestive physiology, nutrient utilization, and sustainable animal production. Despite no explicitly listed awards, his active involvement in high-impact projects underscores his expertise. Knudsen advises on various grants and leads interdisciplinary teams focused on gut health, feed efficiency, and environmental sustainability in livestock farming.

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Mette Erecius PoulsenView profile

Researcher

Technical University of DenmarkDenmark

Mette Erecius Poulsen is a Senior Adviser at the National Food Institute (DTU Food) of the Technical University of Denmark, leading the Research Group for Analytical Food Chemistry. She serves as Principal Investigator for critical national and European food safety initiatives, including Denmark's National Reference Laboratories for pesticide residues on cereals and fruit & vegetables since 2006, and the ongoing National Wildlife Surveillance project since 2012. Her work directly supports UN Sustainable Development Goals related to food safety and environmental protection. Her research expertise centers on pesticide residue analysis across complex matrices, with a strong emphasis on advanced mass spectrometry techniques including liquid chromatography-tandem MS (LC-MS/MS), gas chromatography-MS (GC-MS), and high-resolution Q-Orbitrap systems. Key interests include: Method development for micro-solid phase extraction (µSPE) Wildlife exposure pathways in agricultural ecosystems Pesticide fate in food processing (e.g., beer production) Analysis of co-formulants in plant protection products Human biomonitoring via urine testing Validation of contaminant detection in feed and cereals Recent publications (2024-2025) demonstrate her leadership in adapting cutting-edge instrumentation for real-world food safety challenges, particularly in optimizing extraction protocols for fatty feed matrices and tracking pesticide migration into beverages. Her work bridges laboratory innovation with national surveillance systems. Poulsen directs multiple long-term research projects funded through national agreements and European partnerships: National Wildlife Surveillance (2012–present) NRL-C: National Reference Laboratory for pesticide residues on cereals (2006–present) NRL-FV: National Reference Laboratory for pesticide residues on fruit & vegetables (2006–present) EURL-CF: EU Reference Laboratory for pesticides in cereals (Framework Partnership Agreement SANCO/2006/FOOD SAFETY/00252) Et pilotprojekt - Eksponeringsveje for pesticider i harer i agerlandet (2021-2024) She actively disseminates knowledge through workshops (e.g., µSPE training sessions in 2022 and 2024), conference presentations internationally, and media engagement including a 2013 press contribution on banana pesticide residues that generated significant social media traction.

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Jens Jørgen SlothView profile

Professor

Technical University of DenmarkDenmark

Jens Jørgen Sloth is a Professor and Head of the Research Group for Analytical Food Chemistry at the National Food Institute, Technical University of Denmark (DTU). His work focuses on trace element speciation analysis, particularly arsenic and cadmium, in food systems using advanced analytical methodologies like ICP-MS and chromatographic separations. PhD: Dr. Scient, Institute of Biology, University of Bergen (2001–2005) MSc: Chemical Engineering, DTU (1989–1995) His research spans food safety, bioavailability of trace elements, and nanoparticle characterization. Current projects include Cadmium-chelating compounds in plant-based foods , clean label cheese processing , and kelp-derived nutrients . Recent publications highlight trends in analytical food chemistry, including SEC-ICP-MS for heavy metal speciation, ultrasound applications in dairy, and sustainable extraction from marine byproducts. His work aligns with UN SDGs for food safety and sustainable ingredient development. Member, CEN TC275 Working Group 10 (1999–2001, 2005) Member, CEN TC327 Working Group 4 (2005) Organizing Committee, Nordic Conference in Plasma Spectrochemistry (2008) As a supervisor, he guides PhD candidates working on food safety and analytical methods. He also consults national/international authorities on trace element dietary exposure.

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Simon Krogh AndersonView profile

Lecturer

University of CopenhagenDenmark

Simon Krogh Anderson serves as a Lecturer at the Department of Computer Science (DIKU), Faculty of Science, University of Copenhagen. He is an active member of the Machine Learning section which focuses on theoretical foundations and applications across domains including natural language processing, medical image analysis, and biological data modeling. The department participates in the SCIENCE AI Centre and maintains powerful compute resources including the TreeSense platform for remote sensing. His research spans multiple cutting-edge areas in artificial intelligence with particular emphasis on machine learning, quantum computing applications, and algorithmic fairness. Key interests include sustainable AI development, reproducibility in recommender systems, and cross-cultural adaptation frameworks. His work often bridges theoretical computer science with practical applications in environmental monitoring, healthcare analytics, and quantum information processing. Recent publications demonstrate strong interdisciplinary connections across quantum computing, sustainable AI, and fairness metrics. Trends show increasing focus on environmentally conscious AI development, integration of quantum methods with classical machine learning, and ethical considerations in recommendation systems. His work frequently leverages Denmark's extensive health registries and environmental data resources. Anderson actively contributes to the department's research ecosystem through teaching and collaboration within the Machine Learning section. While specific grants aren't detailed in available materials, his publications indicate involvement in projects related to quantum computing infrastructure, environmental monitoring systems, and AI ethics frameworks. The department provides significant computational resources including a dedicated cluster and specialized labs like TreeSense for remote sensing applications. His work appears connected to the SCIENCE AI Centre's initiatives in sustainable computing and quantum information processing.

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Bo Friis NielsenView profile

Professor

Technical University of DenmarkDenmark

Bo Friis Nielsen is a Professor and Head of Section in the Department of Applied Mathematics and Computer Science at the Technical University of Denmark (DTU). His research focuses on queueing theory, particularly matrix-analytic methods, with applications in telecommunication systems and service optimization. He currently supervises PhD students working on projects with Danske Bank (call center efficiency) and DSB S-tog (passenger counting for transport planning). His teaching includes probability theory and stochastic simulation. Education/Background: Formal academic qualifications not explicitly listed in the text. Affiliations: Head of the Mathematical Modelling Section since 2003, affiliated with DTU Compute. Research interests span theoretical advancements in queueing models and practical applications in transportation, healthcare, and industrial systems. He has collaborated with companies like Danske Bank and DSB S-tog, addressing real-world operational challenges. Recent work includes predictive maintenance strategies for multi-component systems and railway defect analysis. Publications emphasize stochastic modeling, maintenance optimization, and transportation analytics. Projects involve developing tools for public transport efficiency and reliability engineering in wind turbines and power plants.

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Bjarne SchmidtView profile

Associate Professor

University of Southern DenmarkDenmark

Bjarne Schmidt is an Associate Professor at the Institute of Mechanical and Electrical Engineering, University of Southern Denmark (SDU). His career spans over two decades, including roles at the Mads Clausen Institute (2008–2020) and Alssundgymnasiet Sønderborg (1993–2008). He holds an MSc in Physics from the Niels Bohr Institute, University of Copenhagen (1992). Research Interests: Schmidt focuses on education-related disciplines such as Learning Strategies Teaching Methods Classroom Environment with interdisciplinary ties to Physics and Engineering . His work explores friction dynamics, magnetic gyro wheels, and mathematical modeling in educational contexts. Publications: Recent studies include experimental analyses of friction in mechanical systems (2024), magnetic gyro mechanisms (2024), and monographs on matrix calculations (2022). His research bridges physics, engineering education, and computational methods. Teaching & Outreach: Schmidt has supervised courses like Tools for Quantitative Analysis (2016–2017) and contributed to media initiatives for high school mathematics, including Free math teaching programs Masterclasses for gifted students at SDU.

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Nicolai Siim LarsenView profile

Assistant Professor

Technical University of DenmarkDenmark

Nicolai Siim Larsen is an Assistant Professor (Tenure track) in the Department of Applied Mathematics and Computer Science at the Technical University of Denmark (DTU), specializing in statistical modeling with applications in finance and healthcare analytics. His work bridges theoretical statistics and real-world data challenges. Education : Ph.D. in Stochastic Financial Models based on Matrix-Analytic Methods, Technical University of Denmark (2022) Dr. Larsen's research centers on multivariate phase-type distributions and matrix-analytic methods , with significant contributions to financial risk modeling and healthcare analytics . His expertise spans survival analysis, sensor data processing, and price optimization frameworks, addressing complex stochastic phenomena in insurance and disease progression monitoring. Analysis of his publications reveals a cohesive focus on advancing numerical computational methods for multivariate data structures. His 2022 Ph.D. thesis established foundations for joint density functions and infinitely divisible distributions, with subsequent work directly applied to commercial pricing strategies and edema patient monitoring systems. Statistical analysis and price optimisation of DJ rental services (2022) AI Denmark: Monitoring disease progression in Oedema patients (2022) KomDigital: Optimal pricing strategies for price monitoring (2022) Stochastic Financial Models based on Matrix-Analytic Methods (PhD project 2018-2023) He actively contributes to academic service as an internal examiner for Statistical Genetics (2025) and instructor for R-based data science workshops, demonstrating commitment to both research leadership and pedagogical development within DTU's Statistics and Data Analysis section.

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Hanne Mørck NielsenView profile

Professor

University of CopenhagenDenmark

Hanne Mørck Nielsen is a Professor and Section Head of the Section for Biologics at the Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen. As Project Leader and Principal Investigator of the Novo Nordisk Foundation-funded Center for Biopharmaceuticals and Biobarriers in Drug Delivery (2017-present), she directs interdisciplinary research focused on overcoming biological barriers for efficient drug delivery of biopharmaceuticals to seriously ill patients. Her educational foundation includes: PhD in Pharmacy (1995-2000) from the Royal Danish School of Pharmacy and Leiden Academic Centre for Drug Research MSc in Pharmacy (1989-1995) from the Royal Danish School of Pharmacy Professor Nielsen's research centers on designing drug delivery systems (DDS) for therapeutic peptides/proteins, antibiotics, and oligonucleotides using carrier peptides, lipids, and biopolymers. She integrates pharmaceutical formulation design with biological matrix interaction studies, emphasizing mucus, epithelia, and biofilm barriers. Her work leverages in vitro and in vivo models to translate findings to human applications, with particular expertise in cell-penetrating peptides and antimicrobial delivery systems. Analysis of her 116 publications (3237 citations, H-index 34) reveals dominant trends in nanoparticle-based delivery across mucosal barriers, pH-responsive conjugates, and advanced characterization of drug-excipient-biological matrix interactions. Recent work focuses on electrospun wound dressings, siRNA hybrid nanoparticles, and mucoadhesion rheology, demonstrating consistent translational emphasis from fundamental mechanisms to therapeutic applications. Her scientific recognition includes: Danish Medicines Agency memberships (2016-2017) AcademiaNet membership (2015) Journal of Pharmaceutical Sciences Editorial Board (2014) Alfred Benzon Foundation Postdoctoral Fellowship (2001-2002) Extensive PhD examination duties (2003-2012) She has supervised seven PhD students on antibiotic formulations, peptide delivery, and lipidated therapeutic peptides, securing major grants from the Novo Nordisk Foundation, Danish Council for Independent Research, and Innovation Fund Denmark. Current projects address saliva-repellent nanofiber systems and quantitative 19F NMR for cellular uptake studies. As leader of the Center for Biopharmaceuticals and Biobarriers in Drug Delivery, she coordinates interdisciplinary teams developing next-generation biopharmaceutical delivery platforms, with recent work highlighted in international conferences including Tartu, Lund, and Lisbon.

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