Thomas SchlichthärleView profile
Assistant Professor
Prof. Dr. Thomas Schlichthärle is a Tenure Track Assistant Professor at the Technical University of Munich (TUM) , holding the Professorship for AI-Guided Protein Design within the TUM School of Natural Sciences and Department of Bioscience . His research bridges machine learning, structural biology, and synthetic biology to develop synthetic proteins that modulate cellular signaling pathways. Education: B.Sc. in Molecular Medicine, University of Tübingen M.Sc. in Molecular Bioengineering, TU Dresden Research at Wyss Institute (Boston) and Max Planck Institute of Biochemistry (Munich) Research Focus: AI-assisted protein design for controlling cellular decision-making processes, with applications in biomedicine and synthetic biology. His lab develops novel protein design methods validated in cell-based systems, centered on creating synthetic proteins that can detect, modulate, or reprogram signaling pathways through oligomeric assemblies. Scientific Awards: Wübben Foundation Fellow (2025) EMBO Postdoctoral Fellowship (2021) Roland Ernst Scholarship (2014) Germany Scholarship (2013) Ferry Porsche Prize (2007) Collaborations & Grants: Collaborated with Prof. David Baker's lab at the University of Washington and participated in high-impact interdisciplinary projects involving DNA-PAINT microscopy and quantitative protein imaging. His work has been supported by competitive fellowships and institutional grants.










