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Professor Eva Kosek holds dual academic positions as Professor of Clinical Pain Research at Karolinska Institutet (since 2015) and Uppsala University (since 2020). She is affiliated with the Department of Clinical Neuroscience and leads the Mechanisms of Pain and Treatment Research Group . Her roles include senior consultant at Uppsala University Hospital's Pain Center. Education: MD from Uppsala University (1986), PhD from Karolinska Institutet (1996). Specializations: Rehabilitation Medicine (1998), Pain Relief (2001). Academic promotions: Associate Professor at Karolinska (2004), Full Professor (2015). Research Focus: Chronic pain mechanisms, neuroimmune interactions, fibromyalgia, and autoimmune pathways. Key projects include the RAFT trial (Rituximab for fibromyalgia autoantibody therapy) and the BACPAP consortium for low back pain phenotyping. She chairs IASP's Terminology Task Force, introducing the 'nociplastic pain' concept. Key Contributions: Discovered anti-satellite glial cell IgG antibodies in fibromyalgia patients, linked to symptom severity. Pioneered neuroimaging studies on pain modulation circuits. Authored over 300 publications, with recent work on cerebrospinal fluid biomarkers and lipid metabolite profiles. Awards: 2024 Roland Melzack Lecture Award from IASP. Recognized for redefining pain taxonomy and translational research. Grants: Active funding includes Swedish Research Council grants on fibromyalgia autoimmunity, environmental exposures, and neuroinflammation. Total grants exceed SEK 100M over her career. Labs/Teams: Leads a multidisciplinary team at Karolinska's Pain Research Center, collaborating internationally on translational pain studies. Active in biobanking initiatives like the Swedish Chronic Pain Biobank.

• Chronic Pain Research
• Neuroimmunology
• Musculoskeletal Disorders
• +3 more

Sara Liin is a Senior Associate Professor at Linköping University, affiliated with the Department of Biomedical and Clinical Sciences within the Faculty of Medicine and Health Sciences. Her research focuses on ion channel dysfunction in cardiac arrhythmias, particularly exploring polyunsaturated fatty acids and endocannabinoids as therapeutic avenues. She holds a PhD in Neurobiology (2011) and a Master in Medical Biology (2005). Her work emphasizes understanding how genetic mutations in cardiac ion channels lead to arrhythmias and developing targeted treatments. Recent studies highlight the role of estrogen in exacerbating arrhythmia risk and the potential of endocannabinoids like ARA-S to rescue mutant channels. Liin has secured grants totaling SEK 64 million and leads a research group investigating lipid-channel interactions and drug development strategies. Key achievements include the Eric K Fernström award (2021) and collaborative projects with institutions like the University of Miami and SciLifeLab. Her lab, part of the Division of Cell and Neurobiology, explores translational applications of ion channel research to combat heart rhythm disorders.

• Cardiac Rhythm
• Ion Channel Dysfunction
• Cardiac Arrhythmias
• +3 more

Antonios Pantazis is an Associate Professor and Docent at Linköping University, affiliated with the Department of Biomedical and Clinical Sciences (BKV) within the Faculty of Medicine and Health Sciences. He leads the Pantazis Laboratory of Cellular Excitability (PaLaCE), focusing on ion channel biophysics and their role in health and disease. His work integrates electrophysiological, optical, and computational methods to study ion channel structure-function relationships, particularly in cardiac and neuronal systems. Research interests include voltage-gated ion channels, cellular excitability, and the molecular mechanisms underlying arrhythmias and neurological disorders. Key contributions involve understanding mutations in genes like SCN5A and KCNA2, which are linked to epilepsy and cardiac arrhythmias. He has been awarded the Swedish Fernström Prize (2021) for his work on ion channels. Publications span topics such as ion channel regulation, molecular transitions in voltage-dependent processes, and drug targets for arrhythmia suppression. His laboratory also explores cutting-edge techniques like voltage-clamp fluorometry and optical methods to visualize protein dynamics. Collaborations include institutions like the Wallenberg Centre for Molecular Medicine (WCMM) at Linköping University, emphasizing translational research in medical technology and bioengineering.

• Ion Channel Biophysics
• Cellular Excitability
• Neuroscience
• +3 more

Professor Peter Larsson is affiliated with Linköping University's Department of Biomedical and Clinical Sciences, part of the Faculty of Medicine and Health Sciences. He holds a position within the Division of Cell and Neurobiology, focusing on ion channel research with clinical applications. His work bridges basic science and translational medicine, particularly in cardiac electrophysiology and neurobiological mechanisms. Education: Not explicitly detailed in provided texts. Research Interests: Larsson's research centers on ion channel dysfunction in disease states, including arrhythmias and epilepsy. He investigates lipid-channel interactions, drug mechanisms (e.g., propofol's effects on epilepsy), and genetic mutations' impact on cardiac and neuronal ion channels. His recent breakthrough demonstrated propofol's ability to restore function in epilepsy-linked ion channels, published in Nature . Publications Trends: Recent work emphasizes translational drug discovery and understanding channelopathies, with contributions to eLife , British Journal of Pharmacology , and Nature . Key themes include SCN5A mutation characterization, endocannabinoid therapy for cardiac channels, and PUFA effects on potassium channels. Awards/Grants: No specific honors or grants mentioned in available texts. Advising: No listed advisees found. His research group appears focused on collaborative projects involving multiple institutions. Labs/Teams: Active in the Division of Cell and Neurobiology, part of a multidisciplinary environment studying cellular structure/function and sensory systems.

• Ion Channel Research
• Cardiac Electrophysiology
• Neurobiology
• +3 more

Maria Lindskog serves as Associate Professor in the Department of Medical Cell Biology at Uppsala University's Faculty of Medicine. Her research examines synaptic tuning mechanisms in the brain, conceptualizing synapses as critical contact points where information is transmitted between neurons. With 80% of brain synapses using glutamate as neurotransmitter, her work investigates how mistuning of glutamatergic transmission relates to cognitive decline and mood disorders. Dr. Lindskog's laboratory employs rat and mice hippocampal slices for field and patch-clamp recordings to directly assess synaptic activity, complemented by immunohistochemistry, western-blot analysis, and animal behavior studies. A significant methodological innovation involves direct recordings from astrocytes, which she identifies as fundamental yet understudied regulators of excitatory synaptic transmission. Her research program bridges basic neuroscience with translational applications, particularly examining how astrocytic dysfunction contributes to psychiatric disorders through altered synaptic connectivity. Analysis of her publication record reveals consistent focus on Alzheimer's disease and depression mechanisms. Recent work investigates astrocytic dysfunction in App NL-F mouse models, amyloid-beta effects on astrocyte metabolism, and novel therapeutic approaches including ketamine and Trk-receptor modulators. Her 2023-2024 publications demonstrate active laboratory operations with multiple high-impact papers in Brain, Journal of Alzheimer's Disease, and Neuroinflammation, indicating ongoing research momentum with clear therapeutic translation goals. As part of Uppsala University's Department of Medical Cell Biology (organized under the Faculty of Medicine), Dr. Lindskog contributes to Sweden's prominent neuroscience community. Her media appearances including Swedish-language videos 'The muscle is the new brain' and 'Can we explain consciousness?' demonstrate commitment to public science communication alongside her research activities.

• Neuroscience
• Neurobiology
• Synaptic Transmission
• +5 more

Saad Nagi is an Associate Professor at Linköping University's Department of Biomedical and Clinical Sciences (BKV), affiliated with the Faculty of Medicine and Health Sciences. He leads the Lab for the Study of Unpleasant Sensations , focusing on translational research into human somatosensation and pain mechanisms using microneurography. His work bridges peripheral nervous system physiology with clinical pain conditions like fibromyalgia and channelopathies. Education: BMedSci (Hons), Western Sydney University, Australia PhD in Human Physiology, Western Sydney University Research Interests: Ultra-fast nociceptors (UFNs) and their role in rapid pain signaling Molecular mechanisms of touch and pain via single-cell RNA sequencing Social touch perception through Aβ fiber encoding PIEZO2-dependent mechanical pain pathways His lab employs advanced techniques including microneurography, machine learning, and collaborative studies with NIH and University of Virginia. Key Achievements: Discovered UFNs challenging classical pain/touch dichotomy (Science Advances, 2019) Identified 16 human somatosensory neuron subtypes (Nature Neuroscience, 2024) Received IASP Early Career Grant and multiple conference awards Awards: Western Sydney University Medal (2009) European Pain Federation Young Plenary Speaker (2023) NIH and Swedish Research Council funding Lab Team: Otmane Bouchatta (Postdoc) Kevin Ng (Postdoc) Oumie Thorell (PhD Candidate) Emma Kindström (Research Engineer) Future work focuses on UFN roles in clinical pain and restoration of sensory deficits.

• Human somatosensation
• Peripheral nervous system
• Pain modulation
• +7 more

Robert Bränström is an Adjunct Senior Lecturer (Docent) at the Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, with active employment from 2020 to 2026. He leads the Endocrine Surgery research group within Karolinska University Hospital's endocrine and sarcoma surgery section—the largest endocrine surgery clinic in the Nordics, treating over 1,000 patients annually with sarcoma and endocrine tumors through multidisciplinary collaboration. His educational credentials include a Docent title (post-doctoral qualification) from Karolinska Institutet in 2008, a Doctor of Philosophy from the Department of Molecular Medicine and Surgery in 1999, and a University Medical Degree from Karolinska Institutet in 1997. Bränström's research centers on Cancer and Oncology, Cell and Molecular Biology, and Surgery, with deep specialization in endocrine tumors (thyroid, parathyroid, adrenal) and gastrointestinal stromal tumors (GIST). His work investigates molecular pathways—including ion channels in hormone secretion, genetic variants in tumor aggressiveness, and targeted therapies like imatinib—while maintaining strong clinical translation through surgical outcomes studies. Recent focus areas include genomic profiling for sarcoma diagnostics, minimally invasive metastasis detection techniques, and molecular mechanisms underlying calcium dysregulation in hyperparathyroidism. Analysis of his 2022-2025 publications reveals consistent emphasis on genomic drivers of endocrine malignancies, surgical innovation for thyroid cancer, and calcium channel physiology. Key journals include Clinical Cancer Research, Endocrine-Related Cancer, and World Journal of Surgery, with collaborative work spanning Karolinska's surgical and molecular teams. While no individual scientific awards are documented, his department received Swedish Cancer Society funding in 2024. No student advisees are listed in the text, though his doctoral thesis (1999) suggests prior graduate mentorship. His research group maintains close ties with Karolinska University Hospital's surgical units for clinical data acquisition. The Endocrine Surgery group operates within Karolinska University Hospital's Solna campus, utilizing both surgical patient data and molecular labs for translational work. Current projects involve TERT promoter screening, Magseed localization technology, and longitudinal imaging of parathyroid cells, reflecting integration of clinical surgery with basic science.

• Cancer and Oncology
• Cell and Molecular Biology
• Surgery

Fredrik Elinder is a Professor and Deputy Head of Department at the Department of Biomedical and Clinical Sciences (BKV) at Linköping University, Sweden. He leads research in molecular physiology of voltage-gated ion channels with a focus on neurological and cardiovascular applications. His work bridges basic science and translational research, particularly in developing drugs targeting epilepsy and cardiac arrhythmias. Elinder's research group investigates how substances modulate ion channel function at the molecular level, with key contributions to understanding potassium channel pharmacology and lipid-channel interactions. His team collaborates closely with SciLifeLab Linköping, leveraging advanced technologies in biophysics and drug discovery. Notable achievements include discovering novel antiseizure compounds derived from conifer resin acids and identifying molecular mechanisms underlying nerve impulse regulation. He has received prestigious recognition including the Onkel Adam Award (2021) for outstanding research contributions. Elinder's work has implications for treating epilepsy, chronic pain, and cardiac disorders, with multiple patents and industry collaborations advancing drug development pipelines.

• Molecular physiology of voltage-gated ion channels
• Neuroscience
• Biophysics
• +3 more

Professor Lisa Juntti-Berggren is a faculty member at Karolinska Institutet's Department of Molecular Medicine and Surgery, specializing in diabetes research with a focus on apolipoprotein CIII (apoCIII). She holds a Docent title from Karolinska Institutet (1997) and has been recognized with the Swedish Society of Medicine's Jubilee Prize (2023) for her contributions to diabetes research. Her work explores how elevated apoCIII levels contribute to diabetes pathogenesis, including β-cell dysfunction, metabolic disorders, and complications like insulin resistance. Key findings include delaying type 1 diabetes onset in mice by lowering apoCIII and identifying its role in obesity-linked insulin resistance. Recent studies (2025-2014) highlight her research on extracellular vesicles, ER stress in β-cells, and therapeutic strategies targeting apoCIII. She collaborates widely, evidenced by co-authored articles and grants from institutions like the Swedish Research Council. Her laboratory is part of the Signal Transduction research group led by Ismael Valladolid-Acebes. Awards include the 2023 Jubilee Prize, acknowledging her discovery of apoCIII's role in diabetes and translational efforts toward drug development. Grants support her exploration of metabolic pathways and apoCIII's diagnostic potential in predicting diabetes complications.

• Cell and Molecular Biology
• Physiology and Anatomy
• Diabetes Research
• +3 more

Olof Patrik Rorsman is a Professor at the Department of Physiology, University of Gothenburg, leading the Diabetes and Pancreatic Islets research group. His work focuses on pancreatic islet physiology, hormone secretion mechanisms, and metabolic regulation in diabetes. Key Research Areas: Glucagon and insulin secretion, calcium signaling in α/β/δ-cells, incretin effects, islet cell communication, and metabolic cross-talk between tissues. Recent Article Trends: Studies on AVP-glucagon interaction, nicotinic receptor effects, SERCA2 in adipose function, PIEZO1 mechanosensing, and GLP-1 metabolite inhibition of glucagon secretion. Collaborations: Works with multidisciplinary teams across institutions, frequently collaborating with researchers like Quan Zhang, Jakob G. Knudsen, and Ingrid Wernstedt Asterholm. His laboratory investigates islet cell electrophysiology, mitochondrial metabolism, and glucagon's role in diabetes complications using both mouse and human models.

• Diabetes
• Pancreatic islet physiology
• Hormone secretion
• +3 more

Sarah McIntyre is an Assistant Professor at Linköping University's Department of Biomedical and Clinical Sciences (BKV), affiliated with the Faculty of Medicine and Health Sciences. She leads the McIntyre Lab and is part of the Center for Social and Affective Neuroscience (CSAN). Her research focuses on understanding how the nervous system processes touch sensations to fulfill physiological, emotional, and social functions, including studies on social touch communication, pain mechanisms, and alcohol reward systems. Key research interests include tactile perception, neural correlates of decision-making related to substance use, and the biomechanics of human interaction. She collaborates across disciplines, such as a project developing smart textiles for chronic pain relief. Recent work has explored neuronal encoding in mechanoreceptors, somatosensory cortical processing, and the role of Nav1.7 ion channels in pain pathways. Publications span neuroscience, psychopharmacology, and biomedical engineering, with emphasis on social touch nuances, sensory discrimination deficits post-stroke, and pandemic healthcare outcomes. McIntyre’s lab integrates experimental psychology, neuroimaging, and biomechanical analysis to decode tactile communication’s emotional and physiological underpinnings.

• Neuroscience
• Sensory Neuroscience
• Neurophysiology
• +3 more

Hjalmar Brismar is a Professor of Experimental Biological Physics at the Department of Applied Physics, KTH Royal Institute of Technology. He also serves as Director of the Cellular and Molecular Imaging Platform at the Science for Life Laboratory and coordinates the National Microscopy Infrastructure (NMI). His research focuses on understanding cellular dynamics through the study of Na,K-ATPase ion pumps and advanced microscopy techniques. He holds a CivIng (1991) and PhD (1996) in Engineering Physics from KTH, followed by postdoctoral training at Harvard University. Research interests include Na,K-ATPase signaling, calcium oscillations, and the development of super-resolution microscopy. Key projects involve the pump's role in cellular stress response and apoptosis, as well as innovations in microscopy for biomedical applications. His team collaborates across KTH and Karolinska Institutet, integrating light microscopy with cell and molecular biology. Recent articles highlight advancements in imaging techniques, ion pump regulation, and pathological mechanisms in kidney and neurological diseases. Awards include membership in the Royal Swedish Academy of Engineering Sciences (2010) and leadership roles in national and international microscopy initiatives. Brismar has supervised 15 PhD students, 8 Licentiate candidates, and 48 M.Sc. theses, reflecting his extensive mentorship in biophysical research. Labs/Teams: Leader of the national super-resolution microscopy infrastructure at SciLifeLab, Swedish node in EurobioImaging, and core member of the Brismar Lab focusing on cellular biophysics and imaging innovation.

• Biophysics
• Cellular Biology
• Ion Pump Mechanisms
• +3 more

Marina Zelenina is a Lecturer at KTH Royal Institute of Technology's Department of Bio-Opto-Nano Fysik. She specializes in the regulation of aquaporins and ion channels in physiological and pathological contexts, with a focus on brain, renal, and neonatal systems. Her research integrates biophysical techniques, cell biology, and clinical applications. Key areas of focus include aquaporin-mediated water transport mechanisms, heavy metal toxicity effects on cellular hydration, and neuroprotective strategies involving astrocyte function. She is actively involved in teaching a wide range of physics and biomedical engineering courses, serving as course responsible, examiner, and instructor for over 15 academic programs at KTH. Research interests emphasize the molecular mechanisms governing water and ion transport across cell membranes, particularly in neurological and renal contexts. Her work bridges basic science and clinical applications, addressing conditions such as congenital diaphragmatic hernia, cerebral edema, and postnatal adaptation challenges. Technical expertise includes confocal microscopy-based permeability measurements and microfluidic device development for cell monitoring. Recent publications highlight advancements in understanding glutamate receptor modulation of astrocyte function, erythropoietin's role in neuroprotection, and the development of novel in situ cellular monitoring systems. Her contributions span peer-reviewed articles, conference presentations, and manuscripts exploring aquaporin roles in K+ transport and quantum dot interactions with epithelial barriers.

• Cell Biology
• Renal Physiology
• Ion Channel Biology
• +5 more

Oliver Seifert is a Senior Associate Professor at Linköping University, affiliated with the Department of Biomedical and Clinical Sciences (BKV) and the Division of Cell and Neurobiology (CNB). His research focuses on dermatological conditions such as lichen sclerosus, psoriasis, and their epidemiological, immunological, and genetic underpinnings. He has contributed to studies on disease incidence, comorbidity patterns, and quality-of-life impacts, leveraging nationwide register data and molecular approaches. Key areas: Cutaneous disorders, epidemiology, immunology, and neurobiology. Recent work includes analyzing lichen sclerosus regional variations and psoriasis severity linked to genetic factors. His division, CNB, investigates cell biology and neurobiology, fostering interdisciplinary research. Notable collaborations include studies on chronic pain mechanisms, ion channel dysfunction in epilepsy, and nano-material applications in medical devices.

• Dermatology
• Immunology
• Neurobiology
• +4 more

Weng-Onn Lui is a Professor in Experimental Oncology at Karolinska Institutet's Department of Oncology-Pathology. His research focuses on small RNA biology, particularly microRNAs' roles in cancer development, drug resistance, and viral oncogenesis. He leads the 'Small RNAs in cancer development' research group, part of the Medical Genetics division under Catharina Larsson's group. Education: PhD in Medical Genetics (Karolinska Institutet, 2002), BSc in Applied Science (Tunku Abdul Rahman College, Malaysia, 1996). Postdoctoral training at Stanford University (2004-2008) under Andrew Fire, and earlier postdoc experience in Molecular Medicine at Karolinska (2002-2004). Previous academic roles include Associate Professor (2014-2024), Senior Lecturer (2016-2024), and Swedish Research Council fellowships (2008-2016). Key research areas include molecular mechanisms of Merkel cell carcinoma (MCC), miRNA regulation in drug resistance (e.g., BRAF inhibitors, imatinib), and Dicer enzyme dysfunction in cancer. His work bridges in vitro and in vivo models to explore miRNA-driven tumor progression and therapy response. Notable awards include AACR-Ortho Biotech Scholar awards (2003, 2005-2006), the Stanford Comprehensive Cancer Center Translational Research Award (2007), and Swedish Research Council fellowships. Current grants include funding from the Swedish Cancer Society and Karolinska Institutet. Advisory roles: Supervised PhD students Hannah Björn Andtback (2022) and Yaije Yang (2021). Active collaborations include teams at Fudan University (China), U Mass Medical School (USA), and Ludwig-Maximilians-University Munich (Germany). His lab investigates viral-driven cancer pathways, miRNA biomarkers, and therapeutic resistance mechanisms. Laboratory affiliations: Based at Karolinska University Hospital-Solna (BioClinicum J6:20) with cross-disciplinary ties to the Catharina Larsson group. Research outputs span over 100 peer-reviewed articles in journals like Autophagy , Cancer Research , and Developmental Cell .

• Cancer and Oncology
• Cell and Molecular Biology
• Medical Genetics and Genomics
• +3 more