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• Type 1 Diabetes
• Beta Cell Biology
• Inflammatory Cytokines
• +5 more

Joachim Størling is an Affiliated Associate Professor at the Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, and a Senior Researcher and Team Leader at the Department of T1D Biology, Steno Diabetes Center Copenhagen. His research focuses on advancing understanding of type 1 diabetes pathophysiology, particularly beta-cell destruction mechanisms and therapeutic interventions to preserve insulin production. His educational background includes: PhD in Health Sciences, University of Copenhagen (2005) MSc in Biology, University of Copenhagen (2001) BSc in Molecular Biology, Roskilde University (1998) Størling's research centers on three interconnected areas: functional genomics to identify causal type 1 diabetes genes operating in beta-cells; deciphering pro-inflammatory cytokine signaling in beta-cell apoptosis; and exploring incretin hormone biology (GLP-1/GIP) for beta-cell protection. His translational approach combines clinical samples, human islets, and animal models to bridge molecular mechanisms with therapeutic applications. Recent publications (2024-2025) demonstrate a strong clinical-molecular synergy, with emphasis on incretin-based therapies (liraglutide, GIP), time-restricted eating interventions, and probiotic approaches. These studies consistently target beta-cell preservation in type 1 diabetes while exploring biomarkers for disease progression and remission. His scientific awards include: Rising Star Award, University Hospital Herlev (2014) Postdoc Award, Independent Research Fund Denmark (2006) Størling has secured over 13 million DKK in research funding as principal investigator, including two major Independent Research Fund Denmark grants (2013, 2017). He serves as a reviewer for leading journals (The Lancet Diabetes & Endocrinology, Diabetologia) and international grant agencies (JDRF, Diabetes UK), and co-founded the CPH-DIRECT diabetes research consortium. He leads a dedicated research team at Steno Diabetes Center Copenhagen focusing on beta-cell biology in type 1 diabetes, with active participation in national and international collaborative networks exploring diabetes pathophysiology and therapeutic innovation.

• Bacteriophage Therapy
• Food Safety
• Zoonotic Diseases
• +5 more

Michela Gambino serves as an Assistant Professor in the Department of Veterinary and Animal Sciences within the Faculty of Health and Medical Sciences at the University of Copenhagen. Her research focuses on Food Safety and Zoonoses, with particular emphasis on bacteriophage applications for controlling bacterial pathogens in animal health and food production systems. Her research spans bacteriophage therapy against enteric pathogens, food safety interventions for meat processing, and veterinary microbiome dynamics . Key themes include developing phage-based alternatives to antibiotics in livestock, understanding host-pathogen interactions in porcine post-weaning diarrhea, and translating laboratory findings to industrial applications. Her work bridges veterinary science, microbiology, and food safety through interdisciplinary collaboration. Analysis of her recent publications reveals a strong trajectory in applied phage research , particularly targeting Enterobacteriaceae in animal models and food systems. Her studies integrate genetic susceptibility (e.g., CHCF1/SNP2 genotypes), microbiome analysis, and industrial-scale validation, demonstrating translational impact from bench to farm and food processing environments. No scientific awards were mentioned in the source material. Information regarding student advising and research grants was not explicitly provided in the available text. Dr. Gambino collaborates extensively within the Department of Veterinary and Animal Sciences (IVH), particularly with researchers specializing in gut microbiology, phage biology, and veterinary infectious diseases. Her work involves both controlled challenge trials and industrial-scale validations, indicating integration within applied research teams focused on sustainable solutions for animal health and food safety challenges.

• Skin Microbiome Research
• Host-Microbe Interactions
• Chronic Inflammatory Skin Diseases
• +3 more

Lene Bay serves as Assistant Professor in the Department of Immunology and Microbiology at the University of Copenhagen, with dual appointments in Bacteriology and the Skin Immunology Research Center. Her research focuses on the intricate relationships between skin microbiota and inflammatory diseases. Her educational background includes a PhD in The Human Skin Microbiota - distribution and composition, completed between January 2015 and February 2018, with the degree awarded on June 20, 2018. This foundational work established her expertise in cutaneous microbial ecosystems. Bay's research program investigates host-microbe interactions in chronic inflammatory skin conditions, particularly atopic dermatitis and hidradenitis suppurativa. Her work employs advanced metagenomic techniques to characterize bacterial communities within different skin microenvironments, revealing how microbial signatures correlate with disease states. Current projects examine intestinal-pulmonary inflammation connections, antimicrobial efficacy in medical devices, and preoperative skin preparation protocols. Analysis of her 33 research outputs shows consistent focus on skin microbiome dynamics, with significant contributions to understanding dermal bacterial signatures in inflammatory diseases. Her work bridges fundamental microbiology with clinical applications, particularly in diagnostic biomarker discovery and therapeutic intervention strategies. Bay maintains active research collaborations across multiple institutions, as evidenced by her international co-authorship network. Her work has generated substantial academic engagement with 15+ PlumX captures for recent publications and significant Mendeley readership. She is affiliated with the Skin Immunology Research Center and conducts research within the Department of Immunology and Microbiology's specialized laboratories. Her team utilizes both human clinical samples and porcine models to investigate skin barrier function and microbial colonization patterns.

• Animal Models
• Neonatal Nutrition
• Premature Birth
• +5 more

Thomas Thymann is a Professor with special responsibilities at the Department of Veterinary and Animal Sciences, University of Copenhagen, with dual appointments in Comparative Pediatrics and Nutrition and Preclinical Disease Biology. His research primarily focuses on developing animal models that mimic human conditions, particularly around birth and weaning periods. University: University of Copenhagen School: Faculty of Health and Medical Sciences Department: Department of Veterinary and Animal Sciences Research Groups: Comparative Pediatrics and Nutrition, Preclinical Disease Biology Thomas Thymann's research interests center on critical developmental transitions in organisms, with particular emphasis on birth and weaning periods. His work investigates how premature birth and early weaning can lead to pathological conditions such as enteritis and other diseases. A major focus of his research involves the development and utilization of a preterm neonatal pig model that displays symptoms similar to premature human infants. This model has been instrumental in studying how various nutritional regimens in early life can significantly affect morbidity and mortality after preterm birth. His research also examines intestinal malfunction and inflammation that can occur when weaning from mother's milk to solid food happens prematurely, especially in developing countries where this can be compounded by malnutrition. His recent publications demonstrate strong trends in neonatal nutrition, gut microbiome research, and the development of animal models for human conditions. Thymann's research particularly emphasizes the physiological mechanisms during critical developmental periods and identifying optimal nutritional regimens to ease transitions to solid food and improve outcomes for preterm infants. His work spans from basic physiological mechanisms to translational applications with potential clinical impact. Development of preterm pig models for human infant conditions Neonatal nutrition and gut development Effects of nutritional interventions on morbidity and mortality Intestinal inflammation and microbiome in preterm infants Translational research from animal models to human applications Physiological mechanisms during critical developmental transitions Thomas Thymann's research has received significant attention, being picked up by 4 news outlets, blogged by 1 source, and widely shared across social media platforms including X (with posts from 13 users) and Bluesky. His work has been accessed by numerous researchers on academic platforms like Mendeley. While specific grant information isn't detailed in the provided text, his extensive publication record (208 research outputs) suggests substantial research funding and active collaboration throughout his career. Thymann leads the Comparative Pediatrics and Nutrition research group where they developed the preterm neonatal pig model. This model has become central to their investigations into neonatal nutrition, gut development, and immune function. His team maintains active collaborations across disciplines to understand the complex interactions between nutrition, gut physiology, and immune responses in vulnerable neonatal populations, with the ultimate goal of improving clinical outcomes for premature infants worldwide.

Mark SmitsView profile

Researcher

• Endocrinology
• Metabolism
• Gut Hormone Physiology
• +5 more

Mark Smits is a postdoctoral researcher at the University of Copenhagen's Faculty of Health and Medical Sciences, Department of Biomedical Sciences, working within Professor Jens Juul Holst's research group focused on endocrinology and metabolism. His academic journey began with medical training in Amsterdam where he earned both Bachelor's and Master's degrees with honors from Vrije Universiteit Amsterdam. Medical Doctor (MD) qualification from Amsterdam PhD in gut-hormone based therapies from Vrije Universiteit Amsterdam (completed with honors) Current endocrinology specialist training Dr. Smits' research centers on gut hormone physiology, particularly mechanisms to enhance glucagon-like peptide-1 (GLP-1) secretion. His work spans molecular mechanisms of hormone secretion, dietary influences on metabolic pathways, and therapeutic applications for diabetes and metabolic disorders. Recent publications demonstrate expertise in incretin biology, gut-brain axis signaling, and translational approaches to metabolic disease. His collaborative research network spans multiple international institutions, with significant contributions to understanding GLP-1 secretion pathways, nutrient-hormone interactions, and metabolic adaptations in disease models. Dr. Smits has published over 65 peer-reviewed articles, with recent work appearing in high-impact journals including Diabetes , American Journal of Physiology , and Diabetes/Metabolism Research and Reviews . As part of Holst's renowned research group, he contributes to cutting-edge investigations into gut hormone-based therapies while advancing his clinical training in endocrinology. His dual expertise in clinical medicine and basic research positions him at the intersection of translational endocrinology and metabolic disease therapeutics.