Brent Doiron is a Professor at the University of Chicago, holding appointments in the Departments of Neurobiology and Statistics, and serving on the Committee on Computational and Applied Mathematics (CCAM). His research integrates nonlinear dynamics and statistical mechanics to study neural circuit variability, focusing on mechanisms underlying neural coding and network learning through collaborations with experimentalists in sensory systems. Education: PhD in Physics (University of Ottawa, 2004) Postdoc: Center for Neural Science at New York University (2017) Previous Roles: Mathematics Professor at University of Pittsburgh (2007-2020), Co-Director of Neural Computation Program at Carnegie Mellon Neuroscience Institute Research interests center on neuronal population dynamics, recurrent circuit mechanisms, and computational neuroscience. Current work investigates correlated variability in cortical networks, inter-areal communication, and stochastic spiking models. Recent publications emphasize cortical stability/gain modulation, asynchronous/synchronous activity balance, and Bayesian inference frameworks. Key themes include sensory processing, network plasticity, and dimensionality reduction in neural coding. Scientific Awards Alfred P. Sloan Research Fellowship in Neuroscience Vannevar Bush Faculty Fellowship Chancellor’s Distinguished Research Award (University of Pittsburgh) Active grants include NIH R01 and R90/T90 awards for neuronal dynamics research and computational neuroscience training programs.
Anirban Paul is an Associate Professor in the Department of Neuroscience and Experimental Therapeutics at Pennsylvania State University, affiliated with the Penn State Neuroscience Institute. His research focuses on cellular and molecular mechanisms of GABAergic inhibitory circuits, with particular emphasis on interneuron biology and its implications in neurological disorders. Dr. Paul's research spans multiple neuroscience domains, with primary focus on GABAergic inhibitory circuits and interneuron biology. His work investigates how specific neuron subtypes, particularly Chandelier cells and cortical interneurons, contribute to brain function and dysfunction. He has made significant contributions to understanding the role of these cells in schizophrenia, Alzheimer's disease, and other neurological conditions. His research integrates molecular, cellular, and systems-level approaches to uncover fundamental mechanisms of neural circuit assembly, plasticity, and function. Key areas include RNA regulation in neuronal development, transcriptomic subtypes of inhibitory neurons, and cell-type specific vulnerabilities in neurodegenerative diseases. His research portfolio demonstrates consistent productivity with publications spanning from 2003 to 2025, showing an evolving focus from basic molecular neuroscience to translational research in neurological disorders. Recent work emphasizes single-cell analysis techniques and the role of specific interneuron populations in disease mechanisms, particularly in schizophrenia and Alzheimer's disease. His publications appear in high-impact neuroscience journals including Neuron, BMC Biology, and Frontiers in Cellular Neuroscience. Dr. Paul has received the NARSAD Young Investigator Award (2018), recognizing his promising research in neuroscience. His scientific contributions have been supported by multiple competitive grants from prestigious organizations including the National Institute on Aging (NIA) and the Brain and Behavior Research Foundation. He serves as Principal Investigator on multiple active research projects, including two major grants from the National Institute on Aging focused on cell-type specific risk and resilience in Alzheimer's disease and aging (2021-2024 and 2024-2026), as well as previous projects from the Brain and Behavior Research Foundation investigating Chandelier cells in schizophrenia. His research program demonstrates sustained funding and scientific leadership in the field of interneuron biology and its clinical implications.
Marc V Fuccillo is an Associate Professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania, where he leads a research laboratory focused on understanding the neural circuit mechanisms underlying behavioral control. His work bridges molecular, synaptic, and behavioral approaches to investigate how striatal circuits regulate mouse behavior from simple motor patterns to complex goal-directed actions. Fuccillo holds dual appointments in the Neuroscience and Cell and Molecular Biology Graduate Groups at Penn and maintains an active laboratory investigating the synaptic and circuit basis of neuropsychiatric disorders. Education: B.A. in Molecular and Cellular Biology and Music Performance (Violin) from Brown University (1998) Ph.D. in Developmental Genetics from New York University School of Medicine (2007) M.D. from New York University School of Medicine (2008) Fuccillo's research centers on the synaptic and circuit mechanisms of behavioral control, with particular emphasis on striatal circuits. His laboratory employs a range of technologies including mouse genetics, in vitro electrophysiology, in vivo imaging, and quantitative behavioral analysis to explore how neural circuits of the striatum regulate behavior and how disruptions in these circuits contribute to neuropsychiatric disorders. His work has particularly focused on autism-associated abnormalities in behavioral control, examining how synaptic adhesion molecules like neuroligins and neurexins shape circuit function and behavior, with significant findings regarding D1 dopamine receptor positive medium spiny neurons in the nucleus accumbens. Analysis of Fuccillo's recent publications reveals a strong focus on striatal circuit function across multiple dimensions. His work spans molecular neuroscience (examining synaptic adhesion molecules), cellular physiology (studying specific neuron types in striatal circuits), systems neuroscience (mapping circuit connectivity), and behavioral neuroscience (quantifying motor learning and decision-making). A unifying theme is how disruptions in specific molecular pathways lead to circuit-level abnormalities that manifest as behavioral phenotypes relevant to neuropsychiatric disorders, with particular attention to autism, OCD, and schizophrenia models. Scientific Recognition: Publications in high-impact journals including Nature Neuroscience, Current Biology, Cell Reports, and Neuron Research supported by multiple NIH grants including NIMH F32, NIMH K01, and HHMI Gilliam Fellowship awards for lab members Fuccillo actively mentors a diverse group of trainees including postdoctoral fellows, graduate students, and undergraduates. His laboratory has produced numerous successful alumni who have gone on to faculty positions, medical residencies, and graduate programs at prestigious institutions. His mentoring approach emphasizes technical skill development across multiple neuroscience disciplines while fostering independent scientific thinking. Current research in his lab is supported by NIH funding focused on understanding the molecular architecture of striatal circuits and their role in behavioral control, with three major research directions exploring molecular logic of striatal circuits, circuit mechanisms of behavioral control, and striatal dysfunction in neuropsychiatric disease models. The Fuccillo Laboratory operates within the Department of Neuroscience at the University of Pennsylvania, with access to state-of-the-art facilities for molecular, electrophysiological, imaging, and behavioral neuroscience research. The lab maintains active collaborations with other neuroscience research groups at Penn and beyond, creating a rich intellectual environment for studying the neural basis of behavior. Current research directions include investigating whether there is a molecular logic to striatal circuit composition, how striatal circuits shape behavioral control, and what mouse models of autism, schizophrenia, and OCD can reveal about striatal circuit dysfunction in disease pathophysiology.
Dr. Hillel Adesnik is a Professor in the Department of Neuroscience at the University of California, Berkeley, and a leading researcher in the neural basis of sensory perception. His lab focuses on cortical microcircuits, optogenetics, and neural coding, with emphasis on visual processing and memory formation. Key Research Areas: Cortical Microcircuits Optogenetic Tools Gamma Band Rhythms Neural Coding Mechanisms Dr. Adesnik has pioneered high-speed optical methods like 3D-MAP and 3D-SHOT to manipulate neural activity. His work spans cortical dynamics, synaptic plasticity, and cortical layer interactions, with applications in understanding learning algorithms and sensory inference. Selected Trends from Publications: Recent preprints and papers highlight advancements in cortical VIP neuron function, channelrhodopsin structures, and inter-areal computations. His team utilizes two-photon holography, cryo-EM, and computational modeling to decode perception-related neural codes. Scientific Awards: NIH Director's New Innovator Award (2013) Dr. Adesnik's lab collaborates with institutions like NIH and develops tools for awake animal studies. Funding includes grants from the Beckman Young Investigator Program and NIH.
University of California, Los AngelesUnited States
Istvan Mody is a Professor at the University of California, Los Angeles (UCLA) with appointments in the Department of Neurology and Department of Physiology . His research focuses on synaptic signaling in health and disease, including mechanisms of GABAergic transmission, calcium homeostasis, and their roles in neurological disorders such as epilepsy, Alzheimer's disease, Huntington's disease, stress, alcoholism, and postpartum depression. He utilizes advanced techniques like patch-clamp electrophysiology, neuroanatomical and immunohistochemical methods, and molecular biology in animal models and human brain tissue . Research Interests: Dr. Mody investigates the physiology, pharmacology, and pathology of synaptic transmission and extrasynaptic receptor activation , with a particular emphasis on GABA(A) receptors and their subunit-specific modulation. His work explores how disruptions in excitation-inhibition balance contribute to neurological diseases, including mechanisms of tonic inhibition , calcium signaling , and neurosteroid interactions . He also studies the effects of chronic stress and hormonal fluctuations on neural excitability and behavior. Publications Trends: Recent studies highlight his work on gamma oscillations in Alzheimer's models, microglial dynamics , and rehabilitation strategies for stroke. His lab develops optical tools like dqGEVI for neuronal activity monitoring and investigates human brain organoids to model network dysfunction in epilepsy and intellectual disability. Laboratory Location: 635 Charles Young Dr S, Los Angeles, CA 90095, United States.
Kamal Sen is an Associate Professor in the Department of Biomedical Engineering at Boston University, serving as Director of the Natural Sounds and Neural Coding Laboratory and Director of Admissions and Recruitment for Master’s Programs. He holds a PhD and MA in Physics from Brandeis University and a BA in Physics from Bates College. His research focuses on understanding how neurons encode natural sounds, particularly in the auditory cortex. Key areas include neural coding efficiency, hierarchical auditory processing, and the role of learning in shaping receptive fields. He developed the BOSSA algorithm to address sound segregation challenges in noisy environments, with applications for hearing aid technology. Sen’s work integrates electrophysiological techniques with theoretical approaches from signal processing, information theory, and systems theory. His lab explores neural discrimination of behaviorally relevant sounds and models cortical processing dynamics using computational frameworks. Recent studies investigate parvalbumin neuron contributions to temporal coding and cortical noise reduction in complex auditory scenes. His publications span neural circuit modeling, fNIRS applications in BCI, and biomimetic algorithms for auditory scene analysis. Research highlights include exploring schizophrenia-related gene effects on neural circuits and developing 3D neurosphere models for Parkinson’s disease.
Alicia Che is an Assistant Professor of Psychiatry at Yale University School of Medicine and serves as Director of Graduate Admissions for the Interdepartmental Neuroscience Program. She joined the Yale Department of Psychiatry in 2021 after completing her postdoctoral fellowship with Dr. Natalia De Marco García at Weill Cornell Medical College and Dr. Gord Fishell at NYU. Her research is conducted through the Che Lab at Yale, where she investigates how early life experiences impact brain circuit assembly and mature function in models of psychiatric illness. Yale School of Medicine, Department of Psychiatry Interdepartmental Neuroscience Program Center for Brain & Mind Health Division of Molecular Psychiatry Wu Tsai Institute Yale Center for the Science of Cannabis and Cannabinoids Dr. Che earned her Ph.D. in Physiology and Neurobiology from the University of Connecticut in 2014, where she worked in the laboratory of Dr. Joseph LoTurco. She received her B.S. with triple majors in Biology, Physics, and Physical Chemistry from Pacific Lutheran University in Washington state in 2009. Her research focuses on understanding developmental trajectories following early life experiences to develop diagnostics and early interventions for psychiatric illnesses. Dr. Che's research examines how sensory inputs, social bonding, stress, and substance exposure impact brain development. She employs a multi-dimensional approach to assess transcriptional, circuit, neuronal activity, and behavioral changes across the entire developmental timeline. Her lab currently focuses on four specific areas: the role of oxytocin in social behavior development, circuit dysfunction in PTSD, early-life cannabinoid exposure effects, and the impact of early life stress on development and adulthood. She utilizes advanced techniques including mouse genetics, slice electrophysiology, and longitudinal in vivo 2-photon imaging on behaving animals. Her most recent publications demonstrate significant contributions to understanding neural circuit development, PTSD mechanisms, and the effects of early life experiences on brain function. Her work spans from molecular neuroscience to behavioral outcomes, with publications in top journals including Nature, Neuron, and Nature Communications. Her research has revealed important insights into how translaminar neuronal activity strengthens cortical columns, how oxytocin facilitates social touch development, and how PTSD affects brain transcriptomics. NARSAD Young Investigator Award (2020) K99/R00 Pathway to Independence Award from NINDS (2019) Dr. Che's work has significant implications for understanding and treating neurodevelopmental disorders, PTSD, and the consequences of early life experiences on mental health. She collaborates extensively with researchers across Yale and beyond, with frequent co-authorship with colleagues including Lin Lin, Alex Kwan, and Christopher Pittenger. Her research program bridges basic neuroscience with clinical applications, aiming to translate findings into potential interventions for psychiatric conditions.
Dr. Jason Yi is an Assistant Professor of Neuroscience at Washington University School of Medicine (WashU Medicine). His research focuses on understanding the molecular pathways that shape nervous system development and function, with particular emphasis on autism spectrum disorders (ASD). He leads the Yi Lab, which investigates the role of the ubiquitin ligase UBE3A in the brain and its implications for neurodevelopmental disorders. Dr. Yi received his BS in Biochemistry and Molecular Biology from Dickinson College in 2001 and his PhD in Pharmacology from Duke University in 2009. His laboratory is broadly interested in the molecular pathways that shape nervous system development and function, with the ultimate goal of understanding how dysfunction in these pathways contributes to disease. The current focus is on autism spectrum disorders (ASD), using genetic information from human patients to guide in vitro and in vivo experiments employing biochemical, genetic manipulation, cell biological, and microscopy techniques. Dr. Yi's research has significant clinical implications, particularly in understanding how UBE3A dysfunction relates to both Angelman syndrome (caused by lack of UBE3A activity) and autism (caused by excessive UBE3A activity). His lab discovered that a single phosphorylation event in UBE3A turns off its ubiquitin ligase activity, and that mutations in this site are linked to autism. This work bridges disease genetics with a mechanistic understanding of ASD neurobiology and aims to define developmental timepoints for ASD onset. Dr. Yi's research has been recognized with numerous prestigious awards: Ruth K. Broad Biomedical Research Foundation Predoctoral Fellowship (2006) F32 Kirschstein National Research Service Award (2011) Christina Castellana Postdoctoral Fellowship (2011-2014) The University of North Carolina Postdoctoral Award for Research Excellence (2015) Bridge to Independence Award, The Simons Foundation (2017) NARSAD Young Investigator Award, Brain and Behavior Research Foundation (2018) Whitehall Foundation Research Grant (2018) Alfred P. Sloan Foundation Research Fellowship (2019) Dr. Yi's research program is supported by significant grant funding from organizations including The Simons Foundation, Brain and Behavior Research Foundation, and the Whitehall Foundation. His work bridges basic molecular neuroscience with clinical implications for neurodevelopmental disorders, particularly autism spectrum disorders. Through his research, Dr. Yi is contributing to a deeper understanding of the molecular mechanisms underlying ASD, which may ultimately lead to new therapeutic approaches and interventions. The Yi Lab maintains a collaborative research environment focused on cutting-edge neuroscience techniques. The lab combines molecular, cellular, and genetic approaches to study UBE3A function and its role in neurodevelopment. Their work utilizes patient-derived genetic information to guide experimental approaches, ensuring clinical relevance to autism spectrum disorders. Dr. Yi is also actively involved in mentoring graduate students and postdoctoral fellows, contributing to the training of the next generation of neuroscientists.
Michelle CD Bridi is an Assistant Professor in the Department of Neuroscience at West Virginia University School of Medicine , with a joint affiliation at the Rockefeller Neuroscience Institute . Her research integrates synaptic plasticity , sleep physiology , and neurological conditions to investigate dynamic synaptic regulation under typical and atypical states. Education: BS , McGill University, 2006 PhD , University of Pennsylvania, 2013 Research Focus: The Bridi Lab explores how daily oscillations in excitation/inhibition (E/I) balance are disrupted in Autism Spectrum Disorder (ASD) , aging , and post-stroke states . Current projects address: 1) synaptic adaptation to sleep/wake cycles, 2) E/I imbalance in neurodevelopmental disorders, and 3) molecular mechanisms maintaining neuronal firing rate homeostasis. Publication Trends: Recent work spans REM sleep plasticity , autism models , and neurodegenerative interventions , emphasizing synaptic oscillations , NMDA receptor pathways , and gene therapy applications. Collaborative efforts with Morgan Bridi's lab extend findings to stress and stroke contexts. Grants & Collaborations: Research is funded by NIH/NIGMS , BBRF , and NSF . The lab actively collaborates with cross-institutional teams and is recruiting postdocs and students for ongoing studies.
Sebastian Seung is a Professor at Princeton University , affiliated with both the Department of Computer Science and the Princeton Neuroscience Institute . His career spans Harvard University (Ph.D., 1990), Bell Laboratories, and Massachusetts Institute of Technology before joining Princeton in 2014. An External Member of the Max Planck Society and 2008 Ho-Am Prize recipient, Seung merges machine learning with neuroscience . Research Focus : Pioneering connectomics , Seung developed technologies for reconstructing neural circuits from high-resolution brain images, including FlyWire for collaborative brain mapping. His work explores brain function, development, and plasticity , drawing parallels between fly visual systems and convolutional networks . Awards & Affiliations : 2008 Ho-Am Prize in Engineering External Member, Max Planck Society Technical Contributions : Led breakthroughs in 3D connected component labeling and high-throughput EM imaging for mammalian brains, partnering with NIH’s BRAIN Initiative to scale connectomics to whole mouse brains. Seung’s team has shifted from EM analysis to interpreting connectomes , focusing on neural circuit function and biological mechanisms in flies and mice. His lab alumni network spans institutions, advancing AI and neuroscience globally.
Ju Lu serves as an Assistant Professor at Lehigh University with office location in Iacocca Hall (room 0111), contactable via phone (610.758-3687) and email (jul724@lehigh.edu). Her academic position reflects active engagement in neuroscience research and education within the university's life sciences framework. Education Background: Ph.D. in Neurobiology from Harvard University (2008) B.Eng. in Microelectronics from Tsinghua University (2002) Research Focus: Dr. Lu's work pioneers investigations into neural circuit dynamics and synaptic plasticity mechanisms using advanced optical imaging technologies. Her research spans: Cortical circuit reorganization during motor skill acquisition across species Stress-induced synaptic alterations mediated by microglia in prefrontal circuits Therapeutic applications of psychedelic compounds for neural circuit restoration Development of three-photon microscopy for deep-brain imaging Genetically-encoded neurotransmitter sensors for in vivo studies This multidisciplinary approach bridges molecular neuroscience, systems-level circuit analysis, and translational mental health applications. Publication Trends: Analysis of Dr. Lu's 15 most recent publications (2016-2023) reveals an evolving trajectory from foundational studies on dendritic spine plasticity toward translational neuroscience. Early work emphasized optical imaging methodology and basic plasticity mechanisms, while her 2021-2023 publications increasingly focus on stress-related circuit disruptions and psychedelic therapeutics. A consistent thread involves combining high-resolution in vivo imaging with behavioral models to establish causal links between neural circuit dynamics and cognitive functions. Honors and Awards: No scientific awards or fellowships were documented in the provided materials. Mentorship and Funding: While specific student mentees and grant funding details are not specified in the source text, her extensive collaborative publication record indicates active supervision of research personnel and successful acquisition of research support. Research Infrastructure: Her methodological expertise in advanced microscopy suggests utilization of specialized imaging facilities, though no dedicated laboratory or research team is explicitly identified in the available documentation.
Dr. Chengcheng Huang is an Assistant Professor in the Department of Neuroscience and Mathematics at the University of Pittsburgh. She holds affiliations with the Center for Neuroscience, the Mathematics Graduate Program, and the Program of Neural Computation at the Center for the Basis of Neural Cognition. Her research focuses on computational modeling of neural networks, exploring circuit dynamics and information processing in sensory systems, particularly the role of neural variability in context-dependent responses. Huang's work is supported by grants from the NIH BRAIN Initiative, NSF CAREER Award, Simons Foundation, and PITT Momentum Scaling Award. Education: PhD in Neuroscience from New York University (2015), B.Sc. in Mathematics from Nanjing University (2010). Postdoctoral training included roles at leading institutions. She teaches courses such as Applied Differential Equations and Introduction to Computational Neuroscience. Her lab, the Huang Lab for Neural Dynamics and Computation, investigates neural variability in network models and its implications for neural coding. Current projects include studying functional roles of interneuron subtypes, attentional modulation, and synaptic plasticity. The lab actively recruits postdoctoral fellows, graduate students, and undergraduates. Awards and recognition include prestigious grants and fellowships, reflecting her impactful contributions to computational neuroscience and mathematical biology.
Lief Fenno, MD, PhD, is an Assistant Professor at The University of Texas at Austin, affiliated with Dell Medical School’s Department of Psychiatry and Behavioral Sciences and the College of Natural Sciences’ Department of Neurology. He is a board-certified psychiatrist specializing in addiction medicine, particularly medication-assisted treatment (MAT) for opioid use disorder. His research focuses on molecular and viral tools to study neuron circuitry and behavior, with applications in precision medicine for neurological and psychiatric conditions. Fenno earned his MD and PhD from Stanford University and a BA in neurobiology from Harvard University. His research integrates neuroscience, bioengineering, and clinical medicine to develop novel tools for understanding neural circuits. Key interests include optogenetics, chemogenetics, and optical imaging of neuronal activity in awake subjects. The Fenno Lab explores mechanisms of neurological diseases, particularly addiction, and aims to translate findings into clinical treatments. Recent work emphasizes brain-wide mapping of neural circuits, including studies on glutamate neuron subtypes and VTA-lateral habenula interactions. His lab also develops sono-optogenetic technologies and nanotransducers for deep brain stimulation. Fenno’s educational background includes residency in psychiatry and a bioengineering fellowship at Stanford, underscoring his interdisciplinary approach to neuroscientific challenges.
Gabriel Koch Ocker is an Assistant Professor in the Department of Mathematics & Statistics at Boston University, specializing in theoretical and computational neuroscience. His research investigates how neural activity encodes sensory information, shapes behavior, and evolves through learning mechanisms. Research Focus: Structure-function relationships in neuronal networks Methodology: Dynamical systems, stochastic processes, statistical physics Collaborations: Experimental validation of computational models Recent publications analyze integrate-and-fire networks, dendritic calcium spiking, inhibition-stabilized circuits, and metastability in stochastic neuronal systems. His group combines mathematical rigor with biological relevance to explore neural coding, plasticity, and functional hierarchy in cortical structures. Key contributions include tensor decomposition approaches to correlation analysis, reconciling recording technique discrepancies, and developing field-theoretic frameworks for compartmental modeling. Work spans from molecular-level channel dynamics (Kv7 channels) to brain-area-level functional organization.
Sara Aton, Ph.D., is an Affiliate Professor in the Department of Molecular, Cellular, & Developmental Biology at the University of Michigan, and an affiliate of the Michigan Neuroscience Institute. Her research focuses on understanding how sleep and waking states influence memory consolidation through synaptic plasticity in neural circuits. She employs behavioral, biochemical, electrophysiological, and optogenetic techniques to study rodent models, particularly examining the roles of acetylcholine and interneurons in memory processing. Key research interests include the dynamics of sleep states (NREM and REM), synaptic plasticity mechanisms, and the impact of sleep disruption on memory formation. Her work addresses how neuronal activity during sleep reactivates learning-related ensembles and regulates biosynthetic processes critical for memory stabilization. Aton has received prestigious awards such as the NIH New Innovator Award (2013) and Alfred P. Sloan Fellowship (2013). Her lab investigates translational applications, including therapeutic interventions for sleep-related cognitive impairments in conditions like Fragile X syndrome. The Aton Lab is a hub for interdisciplinary research, combining molecular, cellular, and systems neuroscience approaches. Her publications emphasize sleep-dependent memory consolidation, synaptic plasticity, and the neural circuits governing these processes. Collaborative efforts span neuropharmacology, optogenetics, and computational modeling to unravel the complex interplay between brain states and cognition.
