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Jessica WilliamsView profile

Assistant Professor

• Neuroimmunology
• Multiple Sclerosis
• Astrocyte Biology
• +5 more

Jessica Williams, PhD is an Assistant Professor in the Department of Neurosciences at the Cleveland Clinic Lerner Research Institute (LRI) with additional faculty appointments at Case Western Reserve University, Kent State University, and Cleveland State University. She serves as the Cleveland Clinic liaison for Kent State University and represents the Clinic on the Executive Council for the Brain Health Institute and the Biomedical Sciences Graduate Program Executive Committee. Education: Postdoctoral Fellowship in Neuroimmunology, Washington University School of Medicine (2017) Ph.D. in Immunology, The Ohio State University (2011) M.S. in Physiology, Purdue University (2006) B.S. in Biology/Chemistry, Lindenwood University (2004) Dr. Williams' research focuses on neuroimmune interactions during multiple sclerosis, particularly examining regional responses of CNS glia to immune stimuli and astrocyte-immune crosstalk. Her lab employs murine MS models, primary human and murine cell analyses, and MS patient lesion assessment to investigate cytokine-mediated neuroprotection and CNS repair mechanisms. Recent work highlights protective astrocyte functions mediated by traditionally deleterious cytokines. Analysis of her 15 most recent publications reveals consistent focus on neuroimmune crosstalk in MS, with increasing emphasis on astrocyte heterogeneity, cytokine signaling (particularly IFNγ), and novel therapeutic targets like immunoproteasomes. Key themes include regional CNS differences in immune responses, glial cell repair mechanisms, and translating basic findings into potential MS therapies. Scientific Awards: Lerner Research Institute Excellence in Education Award (2022) Mentor of the Year Award (2023) Dr. Williams actively mentors the next generation of scientists as evidenced by her CIMER Trained Mentor certification and the graduation of PhD student Brandon Smith. Her research is supported by significant funding from the NIH, National MS Society, W.M. Keck Foundation, Brain Health Research Institute, and Neurological and Vision Impact Area. She regularly serves on study sections for the NIH, National MS Society, and Department of Defense. The Williams Laboratory investigates the interplay between immune and central nervous systems during MS, with current projects examining cytokine-mediated neuroimmune crosstalk for CNS repair and regionally distinct glial responses to inflammation. The lab employs advanced techniques including murine MS models and primary human cell analyses to identify novel therapeutic pathways for MS patients.

• Nuclear Magnetic Resonance (NMR)
• In vivo imaging
• MRI pulse sequence development
• +7 more

Professor Guy Williams is a leading academic at the University of Cambridge with a focus on imaging science and clinical neurosciences, affiliated with Downing College and the Wolfson Brain Imaging Centre . Holding a PhD in Physics from his initial Natural Sciences degree, he specializes in nuclear magnetic resonance (NMR) and MRI techniques for brain imaging. Education: BA, PhD in Physics His research centers on non-invasive imaging of brain structure and function, particularly in traumatic brain injury (TBI) and dementia. His work involves developing novel MRI pulse sequences and advanced data analysis algorithms, including AI-based diagnostic tools. He leads studies on white matter integrity post-trauma, longitudinal dementia assessment, and applications of MRI in disorders of consciousness and addiction. Recent publications highlight collaborations in traumatic brain injury outcomes, AI-guided dementia prediction, and neuroimaging of post-COVID cognitive deficits. His team's work on ultra-high field laminar fMRI and distortion correction methods has advanced clinical neuroscience applications. Key techniques include diffusion tensor imaging (DTI), 7 Tesla MRI, and positron emission tomography (PET/MR). His research spans from basic NMR physics to clinical translation, with a strong emphasis on multi-site studies and real-world diagnostic implementation.

• Biomaterials
• Tissue Engineering
• Regenerative Medicine
• +12 more

Professor Hala Zreiqat AM is a leading biomedical engineer at The University of Sydney , serving as the Director of the ARC Training Centre for Innovative BioEngineering . A Fellow of all major Australian academies (AAS, ATSE, FAHMS, FRSN), she develops 3D printed bioceramics for bone regeneration while championing diversity through initiatives like the IDEAL Society and BIOTech Futures mentorship program. Her work bridges academia, clinical practice, and industry in musculoskeletal research . Research Focus: Her lab creates synthetic bone scaffolds that mimic natural bone architecture, strength, and porosity, enabling non-rejected bone regeneration via patient-matched implants. Key applications include orthopaedic, dental, and maxillofacial repair , with over $18M in competitive funding and multiple patents. Current projects explore AI-driven scaffold performance prediction and anti-senescence strategies for aging-related bone loss. Scientific Trends: Recent publications highlight 3D printed nanovoxelated ceramics , antisenescence biomaterials , and multifunctional theranostic platforms . Her team integrates machine learning for scaffold design, atom probe tomography for interface analysis, and two-photon imaging for cellular monitoring in 3D environments. 2021-2022 Fulbright Senior Scholar 2018 NSW Premier's Woman of the Year 2019 Eureka Prize for Innovative Use of Technology Fellow of Australian Academy of Science (2021) Over $18M in research funding Teaching & Leadership: She designed core courses like Tissue Engineering and Nanomaterials in Medicine , mentoring 158 students in 2020 alone. As Chair of CAAR (2020-2023), she strengthens Australia-Arab collaborations. Her lab trains early-career researchers , with alumni now in academia and industry.

Aditi DasView profile

Professor

• Biochemistry and Chemical biology of Lipids
• Mechanism of Membrane proteins in Nanodiscs
• Enzymology of metalloproteins
• +5 more

Aditi Das is a Full Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology, College of Sciences. She leads the Das Laboratory, which focuses on the biochemistry and chemical biology of lipids, particularly studying cytochrome P450 enzymes and their role in lipid metabolism, endocannabinoid systems, and inflammatory pathways. Her educational background includes: B.Sc. in Chemistry from St. Stephen's College M.Sc. in Chemistry from Indian Institute of Technology, Kanpur (I.I.T) Ph.D. in Chemistry from Princeton University Postdoctoral research at Northwestern University (NSF-NSEC fellow) and Beckman Institute for Advanced Science and Technology, University of Illinois UC Professor Das's research interests center around understanding the physiological role of lipids in sustaining homeostasis and their implications in disease states such as neurodegenerative disorders, cancer, and cardiovascular diseases. Her laboratory specializes in: Enzymology of cytochrome P450s, particularly CYP2J2 epoxygenase Metabolism of ω-3 and ω-6 fatty acids and their derivatives Minor cannabinoid metabolism by cytochrome P450 enzymes Discovery of novel anti-inflammatory lipid metabolites and endocannabinoids Mechanistic studies of membrane proteins using nanodisc technology Her work bridges biochemistry, chemical biology, and pharmacology to uncover novel therapeutic targets related to lipid signaling pathways. Analysis of Professor Das's recent publications (2023-2025) reveals a strong focus on cannabinoid metabolism by cytochrome P450 enzymes, with particular emphasis on how these metabolic processes generate bioactive compounds that interact with the endocannabinoid system. Her research increasingly explores the therapeutic potential of omega-3 derived endocannabinoid epoxides in inflammatory and neurodegenerative conditions. The use of nanodisc technology for studying membrane proteins in near-native environments remains a consistent methodological thread throughout her work, enabling detailed mechanistic insights into enzyme function. Professor Das has received numerous prestigious awards recognizing her research excellence and teaching: 2024 NIH Outstanding Researcher Award (MIRA R35) for established investigators 2024 Vasser Woolley Faculty Fellowship 2023 Plenary Lecture at the International Society of the Study of Xenobiotics (ISSX) 2021 E.L.R. Stokstad Award 2019-2021 List of Teachers Ranked as Excellent 2019 Eicosanoid Research Foundation Young Investigator Award 2019 Zoetis Research Excellence Award 2019 Mary Swartz Rose Young Investigator Award 2015 National Scientist Development Award from the American Heart Association 2022 El Sohly Award from the American Chemical Society Professor Das actively mentors a diverse group of students and postdoctoral researchers, with several former lab members now holding faculty positions or working at prestigious institutions. Her laboratory has secured significant funding from NIH, NSF, and other sources to support research on lipid metabolism, cannabinoid pharmacology, and membrane protein biochemistry. Notable grants include an NIH R35 Outstanding Investigator Award (MIRA), an NIH R21 grant from NIDA, and multiple collaborative grants with other research groups. The Das Laboratory operates within the Petit Institute of Bioengineering and Biosciences (IBB) at Georgia Tech, utilizing state-of-the-art facilities for biochemical and biophysical studies. The lab specializes in nanodisc technology to study membrane proteins in near-native environments, with particular expertise in cytochrome P450 enzymes and their interactions with lipid substrates. Recent work has expanded into collaborative projects involving lipidomics, structural biology, and translational applications of lipid signaling research.

Christopher E. NelsonView profile

Assistant Professor

• Gene therapy
• Regenerative medicine
• Genome editing
• +7 more

Christopher E. Nelson is an Assistant Professor in the Department of Biomedical Engineering at the University of Arkansas, College of Engineering. His lab focuses on developing biologically inspired strategies for controlled drug and gene delivery, particularly in the context of gene therapy and regenerative medicine. He is actively supported by the NIH, DoD, and Arkansas Bioscience Institute. Education: Postdoctoral Fellow – Duke University Ph.D. – Vanderbilt University B.S. – University of Arkansas Research Focus: Dr. Nelson’s lab integrates genome editing technologies with targeted delivery systems to address challenges in treating genetic diseases and promoting tissue regeneration. Major themes include CRISPR/Cas9 delivery , gene regulation in wound healing , and safe-harbor genome integration in skeletal muscle. His work spans viral and non-viral delivery vehicles , including lipid nanoparticles and AAV vectors, with a strong emphasis on preclinical validation in models of Duchenne muscular dystrophy and inflammatory disease. Scientific Awards: Controlled Release Society Postdoctoral Fellowship The Hartwell Foundation Postdoctoral Fellowship NIH Pathway to Independence Award (K99/R00) Funding & Support: The Nelson Lab is currently funded by: NIH NIGMS R35 DoD CDMRP DMD IDEA Award Arkansas Bioscience Institute University of Arkansas Engineering & Honors Colleges Lab & Team: The Nelson Lab is a dynamic, interdisciplinary team working at the intersection of gene editing, biomaterials, and regenerative medicine. They regularly present at national conferences such as ASGCT and NCUR, and mentor undergraduate researchers through SURF and Honors College grants.

• Quantitative PET/CT and SPECT/CT Imaging
• Deep Learning in Medical Imaging
• Motion Correction Algorithms
• +2 more

Chi Liu is a Professor of Radiology & Biomedical Imaging at Yale School of Medicine . He serves as Associate Director of Biomedical Imaging Technology at the Yale Biomedical Imaging Institute and Director for Research Faculty Affairs in the Radiology & Biomedical Imaging department. Education : PhD from Johns Hopkins University (2008) Postdoctoral Training : University of Washington (2010) Certification : American Board of Science in Nuclear Medicine (Nuclear Medicine Physics and Instrumentation) His research focuses on quantitative cardiac and oncological PET/CT and SPECT/CT imaging , emphasizing deep learning algorithms , reconstruction algorithms , data correction , and dynamic imaging . Key clinical applications include early detection of chemotherapy-induced cardiotoxicity , multimodality imaging of heart failure , and motion variability elimination in therapy response assessment . The 15 most recent publications reveal a strong emphasis on deep learning techniques for low-dose imaging , motion correction , and cross-tracer generalizability in PET/SPECT systems. These works span applications in cardiac imaging , neuroscience , oncology , and theranostics . Scientific Award : Bruce Hasegawa Young Investigator Medical Imaging Science Award (2012) Contact: chi.liu@yale.edu | ORCID 0000-0002-7007-1037

Brian HieView profile

Assistant Professor

• Machine Learning
• Computational Biology
• Protein Engineering
• +6 more

Brian Hie is an Assistant Professor of Chemical Engineering at Stanford University , a Dieter Schwarz Foundation Stanford Data Science Faculty Fellow , and an Innovation Investigator at Arc Institute . He leads the Laboratory of Evolutionary Design , focusing on the intersection of biology and machine learning . His prior roles include a Stanford Science Fellow in the Stanford University School of Medicine and a Visiting Researcher at Meta AI . Education: Ph.D. , Electrical Engineering and Computer Science , Massachusetts Institute of Technology (2021) Bachelor’s Degree , Stanford University Research Interests: Brian’s work bridges machine learning and computational biology , with a focus on protein engineering , single-cell RNA sequencing , and viral evolution . His Evolutionary velocity framework predicts protein evolutionary dynamics across timescales, while his Scanorama algorithm enables efficient integration of heterogeneous single-cell datasets. He also develops structure-informed language models for antibody optimization and uncertainty-aware ML for biological discovery. Publication Trends: His recent work (2023) emphasizes structure-based inverse folding for antibody evolution, evolutionary scale modeling , and unsupervised optimization . Earlier studies (2022-2021) cover evolutionary velocity , multi-modal single-cell analysis , and viral escape prediction using natural language analogies. Scientific Awards: Stanford Science Fellow (2021) National Defense Science and Engineering Graduate Fellowship (2019) Advising: He mentors doctoral students including Brandon Ameglio , Garyk Brixi , and Chang M. Yun , with a focus on biological design and computational methods . Labs & Collaborations: His lab collaborates with Bio-X and the Institute for Human-Centered Artificial Intelligence (HAI) , and he maintains affiliations with Sarafan ChEM-H and Stanford Data Science .

Konstantinos KalogeropoulosView profile

Assistant Professor

• Proteomics
• Snake Venom Research
• Protein Structure Prediction
• +3 more

Konstantinos Kalogeropoulos is an Assistant Professor at the Department of Biotechnology and Biomedicine, Technical University of Denmark (DTU), leading research at the Cell Diversity Lab. His work bridges proteomics, computational biology, and snake venom research. Current projects: "The Proteomic Landscape during Influenza Infection" (2022-2025) Supervisor for PhD projects on protease network rewiring in psoriasis and wound exudate degradomics Research interests include: Proteomic analysis of inflammatory diseases Snake venom toxin structure prediction Extracellular matrix biomechanics De novo peptide sequencing algorithms Computational modeling of protease networks Recent article trends demonstrate his work in • Database-free proteomics (InstaNovo/InstaNexus) • Snake venom pathophysiology (V-ToCs clustering) • Inflammatory disease biomarkers (psoriasis, impaired healing) • Extracellular matrix mechanics (fibronectin tension, gut inflammation) Advising: Supervises PhD students Polhaus, C. J. M. and Haack, A. M., focusing on protease networks and wound healing.

Haagen KlausView profile

Professor

• Bioarchaeology
• Paleopathology
• Dental Anthropology
• +6 more

Haagen Klaus is a Professor in the Department of Anthropology at George Mason University, specializing in bioarchaeology, paleopathology, and forensic anthropology. Since 2013, he has directed research on the north coast of Peru, focusing on human skeletal biology, mortuary practices, and the impacts of colonialism and environmental stressors on prehistoric and historic societies. Ph.D., Department of Anthropology, The Ohio State University (2008) M.A., Department of Anthropology, Southern Illinois University (2003) B.A., Department of Anthropology, State University of New York at Plattsburgh (2000) Klaus's research explores biocultural transformations in complex societies, with emphasis on health, violence, identity, and ethnogenesis. His Lambayeque Valley Biohistory Project (founded 2003) investigates skeletal markers of disease, stress, and violence across 10,000 years of Andean history. Methodologies include isotopic chemistry, ancient DNA analysis, and dental phenetics. Recent work (2025) examines oral microbiomes during Spanish colonization, syndemic processes in colonial dynamics, and stress indicators in pre- and postcontact populations. Projects integrate osteoimmunology, ecoimmunology, and life history trade-offs to understand physiological and cultural resilience. Current graduate students under his supervision include Rae-Ocean Blake, Kimberly Hargrave, Megan Jankowski, Emily Schopmeyer, and Celeste Schultheiss. He leads international collaborations involving Peruvian, Japanese, Canadian, and American researchers through the Lambayeque Valley Biohistory Project.

• Sepsis
• Infectious Diseases
• Critical Care Medicine
• +3 more

Dr. Justin Belsky is an Assistant Professor of Emergency Medicine at Yale School of Medicine, serving as the COVID-19 Safety Officer and Co-Director of Resident Research in Emergency Medicine. He holds an MD from Wayne State University School of Medicine (2011) and an MPH from Harvard School of Public Health (2016). His research focuses on sepsis diagnosis and treatment, including biomarkers, clinical trials, and risk stratification tools. He led the Yale site for the VICTAS trial evaluating vitamin C, thiamine, and hydrocortisone in septic shock. Dr. Belsky directs the Yale Emergency Medicine Specimen Biobank, collecting samples from critically ill patients for future research. His awards include the Partners in Excellence Team Award (2016) and an Outstanding Poster Award (2015). He is actively involved in resident research training and clinical guideline adherence studies. Education: MD: Wayne State University School of Medicine (2011) Emergency Medicine Residency: Henry Ford Hospital (2014) Research Fellowship: Massachusetts General Hospital (2016) MPH: Harvard School of Public Health (2016) Research Interests: Early sepsis identification and treatment Biomarker development for critical illness Fluid management strategies in septic shock Micronutrient therapies in sepsis Emergency department quality improvement Recent Work Focus: Fluid resuscitation protocols and guideline adherence Long-term outcomes of sepsis therapies Actin cytoskeleton as a sepsis biomarker Antibiotic timing in sepsis Awards: 2016: Sepsis Care Redesign, Partners in Excellence Team Award 2015: Outstanding Poster Award (Shock Symposium) Grants & Mentorship: Principal investigator for CLOVERS trial (fluid management in sepsis) Co-Director of Yale’s Emergency Medicine Research Training Program Leadership in resident research mentorship and biobank initiatives

Pedro FardimView profile

Professor

• Chemical Engineering for Human Health
• Biochemical Process Engineering
• Biomass Engineering
• +12 more

Pedro Fardim is a Professor at the KU Leuven , affiliated with the Faculty of Engineering Sciences, Department of Chemical Engineering , and leads the Chemical and Biochemical Reactor Technology and Safety (CREaS) division. He also serves as President of EPNOE (European Polysaccharide Network of Excellence) and is a member of multiple institutes including KU Leuven Brain Institute (LBI) , Institute for Single Cell Omics (LISCO) , and Institute for Micro- and Nano-scale Integration (LIMNI) . PhD in Chemistry, State University of Campinas (UNICAMP), Brazil Habilitation in Chemical Engineering, Åbo Akademi University, Finland Pedro’s research focuses on topochemical engineering —mimicking natural bioassembly processes in trees and microorganisms to create sustainable materials and biofabrication technologies . His work spans drug delivery , regenerative medicine , biopolymer engineering , and green chemistry , with applications in pharmaceuticals , cosmetics , and energy . Recent projects include hydrogels for wearable sensors , biohybrid materials for bone tissue engineering , and lignin valorization using hydrotropic solvents. His scientific awards include Fellowships from the Royal Society of Chemistry and the International Academy of Wood Science , along with membership in the American Chemical Society . He teaches Chemical Engineering for Human Health , Biochemical Process Engineering , and Biopolymer-based Sustainable Technologies .

• Nanomedicine
• Drug Delivery Systems
• Cellular Uptake of Nanoparticles
• +3 more

Anna Salvati is an Associate Professor specializing in nanomedicine and drug delivery systems. Her research focuses on nanoparticle-cell interactions, biomolecular corona formation, and the physicochemical properties governing nanomaterial behavior in biological environments. Key research themes include cellular uptake mechanisms, toxicity of nanomaterials, and nanoparticle targeting strategies. Recent publications highlight her work on nanoparticle stability, membrane interactions, and environmental impacts of microplastics. Her studies integrate multiomics approaches, advanced imaging, and interlaboratory validation to address challenges in nanomedicine design and safety testing. Current projects explore the role of high-density lipoproteins in nanoparticle functionality and the modulation of drug release kinetics through material engineering.

Jeppe Lund NielsenView profile

Professor

• Microbial Ecology
• Functional Ecology
• Genomics
• +10 more

Jeppe Lund Nielsen is a Professor in the Department of Chemistry and Life Sciences at the Faculty of Engineering and Science, Aalborg University, Denmark. His research lies at the intersection of microbial ecology, genomics, and environmental biotechnology, with a strong focus on sustainable solutions for wastewater treatment, anaerobic digestion, and environmental monitoring. His primary research interests include Microbial Ecology, Functional Ecology, Genomics, Molecular and Technical Microbiology, Anaerobic Digestion, Metagenomics, and eDNA Metabarcoding . He applies molecular tools to understand microbial community dynamics in engineered and natural systems, particularly in wastewater and marine environments. His work contributes to the UN Sustainable Development Goals related to clean water, sustainable cities, and climate action. The recent publication trends reflect a strong emphasis on environmental applications of microbiome science, including nitrogen cycling in wastewater, bioaerosol exposure in workers, eDNA-based biodiversity monitoring, and valorization of waste streams through biotechnology. His articles frequently appear in high-impact environmental and microbiological journals and demonstrate interdisciplinary collaboration across engineering, ecology, and public health. Among his notable scientific contributions are leadership roles in significant research projects such as the AAU Bubble Project (Power2Proteins), JAMBO seabed impact study, and investigations into biotechnological pesticides. He has also contributed to public discourse through media engagement on topics like pesticide regulation and environmental innovation. Professor Nielsen has supervised PhD students, including M. Eskeldsen, and is actively involved in grants and collaborative research across Europe. He is a key member of research teams focused on environmental microbiology, wastewater biotechnology, and marine impact assessments. His lab integrates molecular biology, bioinformatics, and environmental engineering to address pressing sustainability challenges.

Christina LeslieView profile

Research Professor

• Computational Biology
• Systems Biology
• Machine Learning
• +7 more

Dr. Christina Leslie is a Research Professor and Member of the Computational & Systems Biology Program at Memorial Sloan Kettering Cancer Center (MSK). She leads an active research laboratory focused on developing computational approaches to understand complex biological systems. Dr. Leslie earned her PhD from the University of California, Berkeley and has established herself as a leading computational biologist in cancer research and immunology. Computational & Systems Biology Program, Memorial Sloan Kettering Cancer Center Gerstner Sloan Kettering Graduate School of Biomedical Sciences Dr. Leslie's research focuses on developing novel computational methods to study cellular biological systems from a global and data-driven perspective. Her lab exploits diverse high-throughput functional and genomic data to understand molecular networks underlying fundamental cellular processes, including transcription regulation, pre-mRNA processing, signaling, and post-transcriptional gene silencing. Her algorithmic methods draw heavily on machine learning to build accurate predictive models from noisy and high-dimensional biological data. Key areas of interest include modeling cell-type specific transcriptional programs and dissecting co- and post-transcriptional regulation, particularly microRNA-mediated gene regulation. Analysis of Dr. Leslie's publication record over the last five years reveals a strong focus on computational approaches to cancer genomics, immunology, and epigenetics. Her work bridges multiple disciplines, with a particular emphasis on developing machine learning methods to interpret complex biological data. The publications demonstrate increasing sophistication in integrating multiple data types (genomic, transcriptomic, epigenomic) to understand cancer biology and immune responses. Recent work shows a growing emphasis on single-cell technologies and spatial analysis of tumor microenvironments. Introduction of string kernel methodology for SVM classification of biological sequences Development of algorithms for predictive modeling of gene regulation First systems-level analyses of competition between microRNAs and between target transcripts Dr. Leslie actively mentors numerous graduate students and research associates, with current lab members including Vianne Gao, Alireza Karbalaghareh, Erik Ladewig, and several others. Her lab has received significant research funding to support their work on computational approaches to cancer biology and immunology. The Leslie Lab maintains close collaborations with multiple experimental groups at MSK, facilitating the translation of computational insights into biological understanding. The Leslie Lab operates within the Computational & Systems Biology Program at MSK, with strong ties to both the research and clinical missions of the institution. The lab maintains state-of-the-art computational infrastructure for analyzing large-scale genomic and proteomic datasets and collaborates extensively with wet-lab researchers to validate computational predictions experimentally.

Hong HanView profile

Assistant Professor

• Cancer Biology
• Gene Regulation
• RNA Splicing
• +5 more

Hong Han is an Assistant Professor in the Department of Biochemistry & Biomedical Sciences within McMaster University's Faculty of Health Sciences and a member of the Centre for Discovery in Cancer Research (CDCR). She holds a Canada Research Chair and leads the Han Lab, which focuses on cancer biology, RNA regulation, and innovative high-throughput technologies for therapeutic discovery. Dr. Han earned her Ph.D. from the University of Toronto (2010-2016) and has established herself as a leading researcher in glioblastoma and alternative splicing regulation. Her interdisciplinary research integrates cancer biology, RNA science, and multilayer gene regulation to uncover mechanisms underlying cancer progression and treatment resistance. Her laboratory pioneers integrated technological platforms for large-scale genetic/drug screening and ultra-high-throughput single-cell profiling. The research focuses on three main areas: alternative splicing regulation in cancer (particularly glioblastoma and prostate cancer), multilayer mechanisms of glioblastoma heterogeneity and microenvironment evolution, and multiplexed screening approaches for therapeutic discovery in treatment-resistant cancers. Analysis of Dr. Han's recent publications reveals a strong emphasis on single-cell technologies to characterize glioblastoma heterogeneity, minimal residual disease states, and tumor-immune interactions. Her work increasingly bridges basic RNA biology with translational applications, particularly in developing novel therapeutic strategies targeting splicing networks and immune evasion mechanisms. Canada Research Chair Dr. Han teaches Advanced Techniques in the Biomedical Sciences (BIOCHEM 734). Her research program is supported by multiple funding sources, as evidenced by her extensive publication record in high-impact journals including Nature, Cell, Molecular Cell, and Nature Communications. She employs a comprehensive approach combining in vitro, in vivo, and patient cohort studies with cutting-edge genomic technologies. The Han Lab has developed innovative multiplexed screening platforms that enable simultaneous interrogation of thousands of conditions, ranging from CAR-T cells to small molecule therapeutics. This approach accelerates the discovery of novel cancer targets and therapeutic strategies for treatment-resistant cancers.