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Michael HendersonView profile

Associate Professor

• Parkinson’s disease
• Neurodegenerative disease models
• α-synuclein pathology
• +4 more

Dr. Michael Henderson is an Associate Professor in the Department of Neurodegenerative Science at Van Andel Institute (VAI) and Director of the VAI Brain Bank. His research focuses on neurodegenerative diseases like Parkinson’s and dementia with Lewy bodies (DLB), investigating protein pathologies (e.g., α-synuclein, tau) and genetic risk factors (e.g., LRRK2, GBA1). He earned his B.Sc. in Biological Science from Florida State University, Ph.D. in Neuroscience from Yale University (under Dr. Sreeganga Chandra), and conducted postdoctoral work at the University of Pennsylvania (with Drs. Virginia Lee and John Trojanowski). Promoted to Associate Professor in 2024, his lab combines primary neuron cultures, animal models, and computational modeling to study disease mechanisms and therapeutic targets. Key research areas include: (1) Mapping α-synuclein pathology spread via brain connectivity networks, (2) Evaluating LRRK2 kinase inhibitors and glucocerebrosidase modifiers, (3) Identifying cell-type vulnerabilities using spatial transcriptomics, and (4) Translating discoveries into clinical trials. His lab has published over 120 peer-reviewed papers, including 63 in high-impact journals (2024 alone). Notable grants include a $5.8M NIH grant (2025) studying cellular senescence in Parkinson’s and a $9M Aligning Science Across Parkinson’s award (2021). Awards include the NSF Graduate Research Fellowship (2012) and NIH Ruth L. Kirschstein Award (2017). His team includes 10+ advisees (Ph.D. students, postdocs, and technicians), with active collaborations across institutions like Yale and the University of Pennsylvania. The Henderson Lab aims to accelerate therapies by bridging basic science and clinical applications.

Melissa HazenView profile

Assistant Professor

• Pediatric Rheumatology
• Immune Dysregulation Syndromes
• Quality Improvement in Healthcare
• +3 more

Melissa Hazen is an Assistant Professor of Pediatrics at Harvard Medical School and an Attending Physician in the Hospital Medicine and Rheumatology Program at Boston Children's Hospital. She specializes in pediatric rheumatology, with a focus on immune-mediated disorders and quality improvement initiatives. Dr. Hazen co-founded the MAID clinic for monogenic immune dysregulatory syndromes and directs quality improvement efforts for the Rheumatology Program. Her work includes leadership in the PR-COIN network to develop clinical guidelines for rheumatic diseases like JIA, HLH/MAS, and KD/FUO. Education: Undergraduate at Harvard University (Cambridge, MA), Medical Degree from Yale University School of Medicine (New Haven, CT), Pediatric residency and Rheumatology fellowship at Boston Children's Hospital. Research interests center on immune dysregulation syndromes, pediatric rheumatology care quality, and translational research in JIA pathogenesis. Publications emphasize T/B cell interactions, biomarkers of disease activity, and outcomes of collaborative care models. Her work integrates clinical practice with rigorous quality improvement to enhance pediatric rheumatology standards. Publications highlight advancements in JIA care, cytokine storm syndromes, and healthcare equity through social needs screening. She has developed evidence-based guidelines improving outcomes for life-threatening conditions like macrophage activation syndrome. Awards: None explicitly listed in the text. Grants: Active roles in PR-COIN collaborative studies and quality improvement initiatives. Advising: No formal student advisees listed, though she mentors teams in clinical and research programs. Labs/Teams: Co-director of the MAID clinic, PR-COIN network leader, and Rheumatology Quality Improvement Director. Her work bridges clinical care and academic research to address complex pediatric rheumatology challenges.

Maria ErmolaevaView profile

Researcher

• Aging
• Mitochondrial Biology
• Metabolism
• +9 more

Maria Ermolaeva is a Group Leader at the Leibniz Institute on Aging (FLI) and co-conceived the Center for Aging Research Jena (ZAJ) with Prof. Holger Bierhoff. Her lab employs Caenorhabditis elegans nematodes and mammalian cell/organoid cultures to investigate aging mechanisms, focusing on metabolic alterations, stress responses, and host-microbiome interactions. Key Collaborations: Friedrich Schiller University, Thuringian Ministry of Economics, European Social Fund Research Themes: Mitochondrial homeostasis, Proteostasis, Epigenetic changes, CRISPR screens for ER stress Research Focus: The lab explores how age-related metabolic shifts, proteotoxic stress, and microbiota influence neuronal aging and protein aggregation disorders. Projects include: Characterizing UV-B as a dietary restriction mimetic Linking nucleolar integrity to aging diagnostics Identifying probiotics for longevity Studying circadian clock disruption in proteostasis CRISPR-based longevity gene discovery Publication Trends: Recent work emphasizes mitochondrial bioenergetics, lipid metabolism, and hormetic stress responses. Collaborations span proteomics core facilities and European research networks. Students: Supervises doctoral candidates and postdocs including Prerana Shrikant Chaudhari, Xuemin Gong, and Eberechukwu Maryann Okoli. Core Facilities: Utilizes FLI's proteomics, lipidomics, and CRISPR screening platforms. Partners with Thuringian industry for translational applications.

• Viral Hepatitis
• Hepatology
• Molecular Virology
• +4 more

Professor Mark Douglas is a Professor of Infectious Diseases and Hepatic Medicine at the University of Sydney's Westmead Clinical School, within the Faculty of Medicine and Health. He leads the Viral Hepatitis Pathogenesis group at the Storr Liver Centre and is affiliated with the Westmead Institute for Medical Research. His research focuses on hepatitis viruses (HBV, HCV, HDV), lipid metabolism, and antiviral resistance. He runs liver clinics for hepatitis patients and treats HIV and other infections at Westmead Hospital. Education and professional background: Dr. Douglas completed postdoctoral training at the MRC Virology Unit in Glasgow (2005-2007) and holds a Fellow of the Royal Australasian College of Physicians. He has authored over 100 peer-reviewed publications, including a book on herpes simplex virus transport. Research interests include viral hepatitis pathogenesis, host-virus interactions, and developing personalized therapies. Current projects target HBV cure strategies, HCV resistance surveillance, and improving treatment access for disadvantaged groups. Recent articles highlight advancements in HBV immune response modulation, CAC-driven liver inflammation, and TM6SF2 inhibition for viral secretion suppression. His work bridges basic science and clinical translation, addressing global health challenges in viral hepatitis. Awards: NHMRC CJ Martin Fellowship (2005) Grants: Includes studies on HBV cccDNA diagnostics, HCV resistance surveillance, and TM6SF2 inhibition. As a Research Academic Director in Clinical Sciences, Dr. Douglas supervises postgraduate students like Harout AJOYAN and Delgerbat BOLDBAATAR. Collaborations span institutions in Indonesia (Eijkman Institute, Hasanuddin University) and the UK (University of Glasgow, Wellcome Trust Sanger Institute).

Sandeep DubeyView profile

Lecturer

• Neurodegenerative Diseases
• Genetics
• Neurology
• +3 more

Sandeep Dubey, Ph.D., is an Instructor in the Department of Neurology at Baylor College of Medicine, Houston, Texas. His research focuses on neurodegenerative diseases, particularly ALS/FTD and Huntington’s disease, with an emphasis on understanding molecular mechanisms involving nuclear transport, autophagy, and lipid metabolism. Dubey holds a Ph.D. in Biotechnology from Banaras Hindu University and completed postdoctoral training at Stanford University and Johns Hopkins University schools of medicine. Education: PhD in Biotechnology, Banaras Hindu University (Varanasi, India) MS in Biotechnology, Bundelkhand University (Jhansi, India) BS in Biotechnology and Biochemistry, Bundelkhand University Research Interests: Genetic underpinnings of neurodegenerative disorders Role of nuclear pore complex proteins in ALS/FTD pathogenesis Lipid metabolism dysregulation in motor neuron vulnerability Research Trends: Recent work highlights ESCRT-III/Vps4 complex activation in C9-ALS/FTD models Investigation of polyunsaturated fatty acids as neuroprotective agents Multi-omic approaches to identify ALS subtype-specific biomarkers

Konstantin TsoyiView profile

Assistant Professor

• Pulmonary Disorders
• Cellular Biology
• Molecular Biology
• +3 more

Konstantin Tsoyi, Ph.D., is an Assistant Professor in the Department of Medicine at Baylor College of Medicine, specializing in Pulmonary Medicine. His research focuses on cellular and molecular mechanisms underlying pulmonary disorders, particularly fibrosis and immune-mediated diseases. He holds a position at Baylor College of Medicine, a leading institution for biomedical research and clinical care. His research interests span pulmonary fibrosis, immunology-driven respiratory diseases, and molecular mechanisms regulating tissue repair. Key areas include fibroblast heterogeneity, cytokine signaling in inflammation, and therapeutic targets for fibrotic conditions. Recent publications highlight work on anti-fibrotic agents, immune responses in emphysema, and molecular pathways in sarcoidosis. These studies contribute to understanding disease mechanisms and developing novel therapies. Dr. Tsoyi’s work is supported by interdisciplinary collaborations within Baylor’s medical and research communities. He actively publishes in top-tier journals such as European Respiratory Journal and Science Translational Medicine .

Chowdhury S. AbdullahView profile

Assistant Professor

• Cardiometabolic Diseases
• Heart Failure Mechanisms
• Mitochondrial Dysfunction
• +5 more

Dr. Chowdhury S. Abdullah is an Assistant Professor in Pharmaceutical Sciences and Health Outcomes at The University of Texas at Tyler's Fisch College of Pharmacy, joining in October 2024. He holds a Ph.D. from South Dakota State University and completed postdoctoral training at LSU Health Sciences Center. His research focuses on cardiometabolic diseases, mitochondrial dysfunction, and drug-induced cardiomyopathies. He has over 25 peer-reviewed publications and secured AHA fellowships and grants. Dr. Abdullah also serves as a peer reviewer for high-impact journals like Circulation and Circulation: Heart Failure. Education: Ph.D. in Pharmaceutical Sciences, South Dakota State University (2016) Master of Pharmacy, University of Dhaka (2012) Bachelor of Pharmacy, University of Dhaka (2009) Research Interests: His work explores molecular mechanisms to reduce end-organ damage in heart failure using in vitro and in vivo models. Key areas include Sigma1 receptor modulation, mitochondrial dynamics, and autophagy regulation in metabolic heart disease. He investigates cardiotoxic effects of drugs like methamphetamine and doxorubicin, with a focus on translational pre-clinical models. Publications Trends: His articles emphasize drug-induced cardiac toxicity, mitochondrial dysfunction, and receptor signaling pathways. Recent work explores Sigma1 receptor knockout effects on multiple organ systems, highlighting translational potential for cardioprotective therapies. Awards: 2023 Malcolm Feist Postdoctoral Transition Award 2022 D. Neil Granger Outstanding Postdoctoral Trainee Award 2021 APS Cardiovascular Section Award Teaching & Mentorship: Teaches pathology and physiology courses to medical and allied health students, with strong instructional ratings. Actively mentors students in laboratory research and grant writing. Labs/Teams: Leads a lab at UT Tyler developing molecular strategies to prevent metabolic heart failure, collaborating with cardiovascular research centers to advance pre-clinical therapeutic approaches.

Yanick CrowView profile

Researcher

• Neurogenetics
• Neuroinflammation
• Autoinflammatory Disorders
• +3 more

Yanick Crow is the Head of the Neurogenetics and Neuroinflammation research team, focusing on understanding genetic and immunological mechanisms underlying neuroinflammatory disorders. His work has centered on Aicardi-Goutières syndrome (AGS) and type I interferonopathies, linking monogenic mutations to autoinflammatory pathways. The team investigates nucleic acid-driven inflammation, interferon signaling defects, and potential therapies targeting these mechanisms. Research interests include the interplay between genetic mutations, interferonopathies, and autoimmune diseases such as systemic lupus erythematosus. Collaborations with clinicians and immunologists allow translational studies connecting basic science to clinical applications, with a focus on developing novel treatments for rare and complex immune disorders. Key contributions involve identifying genetic drivers of autoimmunity and proposing JAK inhibitors as therapeutic candidates in interferonopathies. Team members include clinicians (PU-PH), postdoctoral researchers, and PhD students, reflecting multidisciplinary expertise. Publications highlight advancements in understanding cGAS-STING pathway dysregulation, COPA mutations, and mitochondrial nucleic acid roles in pathogenic inflammation. Ongoing work explores molecular mechanisms and clinical trials for interventions in neuroimmunological conditions.

Juan J LoorView profile

Professor

• Animal Sciences
• Nutritional Sciences
• Dairy Production
• +7 more

Juan J Loor is a Professor in the Departments of Animal Sciences and Nutritional Sciences at the University of Illinois. He is affiliated with the Center for Latin American and Caribbean Studies and holds an ORCID identifier: 0000-0003-1586-4365 . His research focuses on understanding the molecular mechanisms underlying metabolic and inflammatory processes in dairy animals, particularly related to lipid metabolism, ketosis, and reproductive health. Key research interests include gene regulation in bovine systems, nutrient signaling pathways, and the interplay between diet and cellular stress responses. He explores topics like fatty acid-induced cellular damage, autophagy mechanisms, and the role of metabolites in livestock health. His recent work highlights advancements in understanding how dietary interventions affect ruminal microbiota, milk composition, and overall animal productivity. He has also contributed to identifying genetic factors influencing seasonal reproduction in dairy goats and mitigation strategies for metabolic disorders. Scientific Awards: AFIA - ASAS Award in Ruminant Nutrition Research (2018) Animal Growth and Development Award (2019) Bouffault International Animal Agriculture Award (2025) College Faculty Award for Excellence in Research (2010) Elanco Award for Excellence in Dairy Science (2016) Dr. Loor’s research group collaborates internationally, focusing on metabolic and immune mechanisms in dairy cows, goats, and other ruminants. His work bridges basic science with practical applications in sustainable livestock management.

• Alzheimer's disease
• Cardiovascular diseases
• Cell biology
• +4 more

Associate Professor Ingrid Gelissen is an academic in the School of Pharmacy at the University of Sydney, serving as Academic Director for Sydney/Camperdown (Pharmacy/Concord). She holds a MAgSci in Nutrition from Wageningen University (Netherlands) and a PhD from the Heart Research Institute/University of Sydney. Her career includes postdoctoral roles at UT Southwestern (USA) and UNSW Sydney, supported by a Vice-Chancellor’s Fellowship. She transitioned to academic roles in 2010, advancing to her current position in 2020. Her research focuses on ABC transporters’ role in Alzheimer’s disease and pharmacists’ roles in nutrition education. Research interests include amyloid-beta export mechanisms via ABC transporters (e.g., P-glycoprotein) and ABCG1/ABCG4, alongside exploring pharmacists’ contributions to nutrition counseling. Key grants include a 2016 Thompson Fellowship (targeting Alzheimer’s) and a 2010 NHMRC Project Grant (ABCG1 regulation). She supervises HDR student Samar Elsayed on 'Nutrition in Pharmacy Practice'. Publications span 2022–2005, emphasizing cholesterol homeostasis, ABC transporter biology, and Alzheimer’s pathology. Notable work includes a 2017 Springer edited book on cholesterol methods. Awards include the NHMRC PhD scholarship and Thompson Fellowship. Teaching spans pharmacokinetics, cardiovascular medicines, and nutrition for pharmacy practice.

• Microbiota-Gut-Brain Axis
• Neuroscience
• Immunology
• +5 more

Professor Melanie Gareau leads research on the microbiota-gut-brain axis at the University of California, Davis, focusing on early-life microbiota dysbiosis and its long-term neurological and physiological effects. Her work integrates microbiology, immunology, and neuroscience to address disorders such as Angelman syndrome and postacute COVID syndrome. Education: BS (McGill, 2001), PhD (McMaster, 2006), postdoctoral training (Hospital for Sick Children, Toronto). Grants: Principal Investigator (NIH, FAST Foundation, UC Davis SOM) and Co-Investigator on projects studying microbiome-brain interactions, wound infection impacts, and inflammatory bowel disease models. Research Interests: Microbiota-gut-brain axis development, probiotic interventions, microbial-immune-neural crosstalk, and translational applications in neurological and gastrointestinal diseases. Awards: Chancellor’s Fellow (2023), APS New Investigator Award (2018), multiple travel and fellowship recognitions. Lab: Gareau Lab explores microbiota interactions in health and disease, with projects on microbiome modulation for cognitive benefits and microbiome restoration strategies.

Carla RibeiroView profile

Associate Professor

• Inflammatory Responses
• Airway Diseases
• Calcium Signaling
• +5 more

Carla Ribeiro, PhD, is an Associate Professor at the UNC School of Medicine, University of North Carolina at Chapel Hill. Her research focuses on inflammatory mechanisms in airway diseases such as asthma, cystic fibrosis, and COPD. She investigates calcium signaling, mitochondrial function, and the unfolded protein response (UPR) in airway epithelia. Her team made groundbreaking discoveries linking IRE1α/β pathways to mucin production and cytokine regulation. Education: Federal University of Pernambuco, Medical Degree (1981) Duke University, PhD (1992) Postdoctoral Fellowship, National Institute of Environmental Health Sciences (1998) Key research areas include the role of UPR in pulmonary inflammation and cigarette smoke-induced epithelial dysfunction. Her work bridges basic cellular biology with translational respiratory medicine. Current studies explore additional UPR branches and their impact on airway disease pathogenesis.

• Abdominal Organ Transplantation
• Liver Transplantation
• Kidney Transplantation
• +9 more

Linda S. Sher, MD, FACS is a Professor of Clinical Surgery and Chief of the Division of Clinical Research in the Department of Surgery at Keck School of Medicine of the University of Southern California. She serves as Chair of the Biomedical Institutional Review Board and Chief of the Division of Clinical Research at the Keck School of Medicine. Dr. Sher is a highly respected expert in abdominal organ transplantation, specializing in kidney, liver, and pancreas transplant surgery, including living donor transplants. Dr. Sher completed her medical education and surgical residency at Mount Sinai School of Medicine in New York, followed by fellowship training in Liver and Kidney Transplantation at the University of Pittsburgh. After her fellowship in 1988, she helped establish two liver transplant programs in Los Angeles before joining the USC program in 2001. Dr. Sher's research focuses on decreasing the side effects of immunosuppressive medications used after transplant surgery and identifying better ways to detect organ rejection. Her extensive work spans immunosuppression, chronic rejection, disease recurrence, infection prophylaxis, and hepatobiliary surgery. She has participated in and overseen over 50 research projects, contributing significantly to the development of clinical and basic science research components of the USC Abdominal Organ Transplantation Program. Analysis of Dr. Sher's recent publications reveals a strong focus on liver transplantation, tumor biology, and immune response mechanisms. Her work spans molecular pathways in liver disease, technical optimization of transplant procedures, and clinical outcomes research. Key themes include spatial transcriptomics for understanding liver disease, immune exhaustion in transplant rejection, tumor-initiating stem cells, and transfusion-free surgical strategies. Her research bridges basic science discoveries with clinical applications in transplantation medicine. Dr. Sher has maintained extensive professional society memberships throughout her career, including: American College of Surgeons (1992-2014) American Society of Transplant Surgeons (1993-2014) International Liver Transplantation Society (1993-2014) American Association for the Study of Liver Diseases (1990-2014) Western Association for Transplant Surgeons (1990-2014) As Chief of the Division of Clinical Research, Dr. Sher oversees the implementation of clinical trials for the entire Department of Surgery at Keck School of Medicine. She has been instrumental in establishing research protocols and infrastructure to support clinical investigations across surgical specialties. Her leadership has facilitated numerous grants and collaborative research initiatives focused on improving outcomes in transplantation medicine and surgical care. Dr. Sher leads research teams focused on abdominal organ transplantation, with particular emphasis on liver transplantation. Her work spans both clinical trials and basic science investigations, integrating multiple disciplines to advance the field of transplantation medicine. She is one of the original editors of Current Opinion in Organ Transplantation, contributing to the dissemination of knowledge in the field.

Filip HammaréusView profile

Research Fellow

• Cardiovascular Disease
• Extracellular Matrix Biomarkers
• Aortic Dilation
• +3 more

Filip Hammaréus is a Research Fellow at Linköping University, combining his role as an intern physician with cardiovascular research. He is affiliated with the Department of Health, Medicine and Caring Sciences and the Division of Diagnostics and Specialist Medicine. His work focuses on extracellular matrix biomarkers in blood and their association with cardiovascular risks, such as coronary artery disease and aortic dilation. Education & Career: Accepted into medical school at Linköping University (2017) Joined 'forskarlinjen' (research program) in 2021 PhD student since August 2021 Master of Science in Medicine (2023) Intern Physician at Region Jönköpings län since February 2023 Research Interests: His studies explore how biomarkers like collagen α1 chain and wall shear stress patterns predict cardiovascular risks. He investigates mechanisms linking inflammation, collagen synthesis, and vascular pathology in conditions like aortic dilation and coronary artery disease. Key Projects: SCAPIS: A national cohort study using imaging and biomarkers to assess cardiovascular risks AscA-studien: Investigating aortic dilation and its progression SCAPIS Leukocyte: Linking immune responses, diet, and atherosclerosis Collaborations: Works with researchers like Lena Jonasson (Dean/Professor), Lennart Nilsson (Associate Professor), and Chiara Trenti (Postdoc) on interdisciplinary cardiovascular projects. News Contributions: His team’s discovery of abnormal blood flow patterns damaging the aorta (2024) highlights translational impacts of his research.

• Cancer Biology
• Non-coding RNA
• Breast Cancer Heterogeneity
• +2 more

Róża Przanowska is a Postdoctoral Research Fellow in Biomedical Engineering at the University of Virginia, specializing in non-coding RNAs in cancer and development. Her research focuses on breast cancer heterogeneity using novel organoid models and lncRNA functional studies. She collaborates with Dr. Kevin Janes and Dr. Shayna Showalter on translational projects supported by the National Cancer Institute and UVA Coulter Center grants. Education: PhD in Biochemistry and Molecular Genetics (UVA, 2021), MSc and BSc in Biotechnology from University of Warsaw, with international training at Max Planck Institute (2014) and a Fulbright Scholarship at UVA (2015). Research interests include lncRNA structure-function relationships, tumor heterogeneity modeling, and translational oncology. Her work bridges basic science and clinical applications through organoid-based patient-specific models. Key achievements include developing zero-passage organoids for breast cancer studies, leading to a 2024 Coulter Center award. Her research has been recognized with over 20 awards including the NCI F99/K00 fellowship (2020-2025) and multiple institutional awards for research and leadership. Grants include NIH K00CA253732 studying lncRNA heterogeneity in ER+ breast cancer, and Coulter funding for organoid-based clinical trial support (POWER II). She also contributed to the Hamlin Lecture Series and taught in the Biomedical Sciences Summer Prep program (2018-2020). Her lab focuses on cancer systems biology, with collaborations in tumor organoid development and molecular mechanisms of lncRNA-driven heterogeneity. Current efforts aim to translate organoid models into clinical decision tools for breast cancer therapies.