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Minh GantherView profile

Researcher

• Soil Ecology
• Plant Gene Expression
• Rhizosphere Studies
• +3 more

Minh Ganther is a dedicated researcher at the Helmholtz Centre for Environmental Research - UFZ (UFZ), where they have been employed as a PhD student in the Department of Soil Ecology since 2018. Working under the supervision of PD Dr. Mika Tarkka at Universität Leipzig, Ganther contributes to cutting-edge research at the intersection of plant biology, soil science, and microbiology. Ganther's academic background includes: M.Sc. in Biochemistry from Universität Leipzig (2014-2017), with thesis on "Characterization of NPY receptors in murine hypothalamic cells" B.Sc. in Biochemistry from Universität Leipzig (2011-2014), with thesis on "Investigation of the NPY binding pocket at the human Y1 receptor" As a key contributor to the DFG-funded priority program SPP2089 (Rhizosphere Spatiotemporal Organisation), Ganther leads the ROOTGENES project which investigates the complex relationships between maize root architecture, gene expression, and the surrounding microbiome. Their research addresses critical questions about how soil properties, plant genotype, and microbial interactions influence root development and function in agricultural systems. Ganther's research methodology integrates controlled climate chamber experiments with field sampling to capture both early and late emerging properties in the rhizosphere. This interdisciplinary approach combines molecular biology, microbiology, and soil physics to unravel the spatiotemporal dynamics of plant-microbe-soil interactions. Through collaborative efforts with institutions including Julius-Kühn-Institut in Braunschweig and Universität Köln, Ganther has established a robust research network focused on plant growth-promoting bacteria and protist microbiota in the rhizosphere. Their work has significant implications for sustainable agriculture and ecosystem management. Ganther's scientific contributions have been recognized through presentations at major conferences including the EGU General Assembly and Botanikertagung, demonstrating the relevance and impact of their research within the scientific community.

Rajat SinghView profile

Adjunct Professor

• Autophagy
• Metabolic Regulation
• Lipid Metabolism
• +3 more

Rajat Singh, MB, BS, MD is an Adjunct Professor at the University of California Los Angeles (UCLA), holding appointments in the Department of Medicine (Endocrinology) and the Department of Developmental & Molecular Biology. His research focuses on autophagy's role in metabolic regulation across physiology, obesity, and aging. Singh leads the Lab of Rajat Singh, investigating how autophagy modulates lipid metabolism, energy homeostasis, and neural mechanisms controlling feeding behavior. His work employs biochemical, immunohistochemical, and in vivo approaches in mouse models to study organ-specific autophagy effects. Key areas include understanding how autophagy failure contributes to metabolic aging and developing interventions to counteract metabolic decline through dietary strategies like time-restricted feeding. His lab also explores autophagy's interplay with circadian rhythms and mitochondrial dynamics in metabolic disorders. Research Interests : Singh’s work spans autophagy mechanisms, lipophagy, metabolic aging, hypothalamic signaling, and the impact of dietary interventions. He investigates how autophagy regulates lipid storage mobilization in neurons and peripheral tissues, linking these processes to obesity, diabetes, and age-related metabolic dysfunction. Recent studies highlight autophagy’s role in circadian clock regulation and mitochondrial health, with implications for neurodegenerative diseases and cardiovascular health. Labs/Teams : The Lab of Rajat Singh integrates interdisciplinary approaches to study metabolic and cellular biology, collaborating on projects involving autophagy’s role in energy balance, aging, and disease. Key collaborations include work on autophagy-circadian clock interactions and mitochondrial quality control in metabolic stress.

Emanuel GasserView profile

Lecturer

• Metabolic Epigenetics
• Nutrition Science
• Diabetes Research
• +3 more

Dr. Emanuel Gasser is a Lecturer at the Department of Health Sciences and Technology at ETH Zürich. He leads the Laboratory of Nutrition and Metabolic Epigenetics within the Institute of Food, Nutrition and Health. His research focuses on understanding how metabolic states are influenced by epigenetic mechanisms, particularly in obesity, diabetes, and lipid metabolism. Gasser’s work bridges nutritional science with molecular biology to explore interventions targeting metabolic disorders. Key research areas include the role of FGF1 in metabolic regulation, epigenetic memory in adipose tissue, and the development of immune-evasive islet organoids for diabetes treatment. His studies often integrate stem cell technologies, epigenetic profiling, and metabolic disease modeling. Publications highlight advancements in FGF1 signaling pathways, mechanisms of metabolic memory post-weight loss, and innovative approaches to overcoming immune rejection in islet transplantation. Gasser collaborates broadly in metabolic epigenetics and translational medicine, contributing to both fundamental science and clinical applications.

• Metabolism
• Diabetes Research
• Obesity
• +5 more

Professor Lora Heisler is the Chair in Human Nutrition at the University of Aberdeen, School of Medicine, Medical Sciences and Nutrition. She is also Director of Research at the Rowett Institute and a member of the Aberdeen Cardiovascular and Diabetes Centre. Her research focuses on brain circuits regulating energy homeostasis, metabolism, obesity, and type 2 diabetes. She holds a PhD from Tufts University (1997) and has held postdoctoral positions at UC San Francisco and Harvard Medical School. She relocated her lab to Aberdeen in 2014 to leverage the Rowett Institute’s obesity research expertise. Her research interests include identifying therapeutic targets for obesity and diabetes through studies on serotonin and GLP-1 signaling pathways. She leads the MOOMIN Lab, which investigates mechanisms of obesity, insulin sensitivity, and nutrition. Key achievements include groundbreaking discoveries on serotonin receptor therapeutic mechanisms and the role of GPR75 in metabolic disorders. Her work is funded by BBSRC, MRC, Diabetes UK, and the Wellcome Trust. Recent awards include the Outstanding Scientific Achievement Awards from the American Diabetes Association and Obesity Society. She advises multiple students and collaborates on international conferences, including co-organizing the 2026 Keystone Conference on Obesity Therapeutics. Her lab includes postdocs like Dr Aurelio Franco Garcia and students such as Imogen McMichael, with notable contributions to understanding brain circuits regulating appetite and metabolism.

Alastair Victor FergusonView profile

Professor

• Neurosciences
• Cardiovascular Physiology
• Metabolic Regulation
• +3 more

Alastair Victor Ferguson is a Professor in the Department of Biomedical and Molecular Sciences at Queen's University, affiliated with the School of Medicine and Faculty of Health Sciences. His research focuses on the central nervous system's role in autonomic processing, particularly hypertension and obesity. He holds cross appointments at the Centre for Neuroscience Studies and the Translational Institute of Medicine (TIME). Dr. Ferguson's education includes a BSc in Biological Sciences (Birmingham University) and a PhD in Neurosciences (University of Calgary). His work integrates multidisciplinary approaches to study autonomic control centers, leveraging electrophysiology and molecular tools. His lab investigates how central circuits regulate critical physiological variables like blood pressure, glucose, and sodium levels. Key research areas include adipokine signaling (e.g., adiponectin, leptin), hydrogen sulfide's cardiovascular effects, and neuronal responses to metabolic signals. He collaborates with institutions like the Canadian Institutes of Health Research and NIH. Notable trainees include researchers studying CCK, nesfatin-1, and BDNF in autonomic nuclei. Funding sources include CIHR, Heart and Stroke Foundation, and NIH grants. His lab's recent work explores hydrogen sulfide's role in blood pressure regulation and the subfornical organ's role in metabolic signaling. He advises PhD and MSc students on topics like SFO neuron electrophysiology and PVN function. His work bridges basic neuroscience with translational medicine, emphasizing autonomic dysfunction in chronic diseases.

Charlie HindmarchView profile

Assistant Professor

• Genetics
• Genomics
• Molecular genetics
• +11 more

Dr. Charlie Hindmarch is an Assistant Professor in the Department of Medicine at Queen's University, affiliated with the School of Medicine and Faculty of Health Sciences. He holds cross-appointments as Director of the Genomics, Transcriptomics, and Molecular Medicine laboratory at the Queen's CardioPulmonary Unit (QCPU) and Scientific Operations Director for the Translational Institute of Medicine (TIME). His research focuses on pulmonary arterial hypertension (PAH), genomic/transcriptomic profiling, and the role of biological sex in cardiovascular diseases. He employs cutting-edge tools like next-generation sequencing and mass cytometry (CyTOF). Dr. Hindmarch holds a PhD in Neuroscience and Endocrinology from the University of Bristol (2009), with prior postdoctoral training there and visiting professorships at the University of Malay and Federal Rural University of Rio de Janeiro. His work spans over 43 publications with an h-index of 17. Research Interests: Genetics, Genomics, Molecular genetics, Analytical biochemistry, Pulmonary Hypertension, Cardiology, Translational Medicine, DNA computing, and Animal Models of Disease. His lab specializes in transcriptomics, proteomics, and bioinformatics. Key roles include leading the TIME Institute's strategic plan and managing advanced equipment (e.g., mass cytometer) at QCPU. Current supervision includes a Master's student, Abhishek Shastry. His work integrates genomic, proteomic, and clinical data to bridge basic and translational research in cardiovascular diseases.

• COVID-19
• Post-COVID Syndrome
• Respiratory Medicine
• +5 more

Dr. Errol Richardson is an active researcher with significant contributions to both neuroendocrinology and post-COVID condition research. He is prominently involved with the PHOSP-COVID Study Collaborative Group, one of the largest international efforts to understand long-term consequences of SARS-CoV-2 infection. His research interests span two primary domains: 1) The physiological mechanisms underlying post-COVID respiratory symptoms, particularly dyspnea and sleep disturbances, and 2) The neuroendocrine regulation of metabolic processes, with earlier work focusing on hypothalamic control of glucose homeostasis. The connection between these areas reflects an integrated approach to understanding physiological regulation across multiple body systems. Dr. Richardson's publication record shows a transition from fundamental neuroendocrinology research (2015-2018) to clinical translational work on post-COVID conditions (2023-2024). His recent articles in high-impact journals like The Lancet Respiratory Medicine and Immunity and Ageing demonstrate his significant contributions to understanding immune aging in COVID-19 and the relationship between sleep quality and respiratory recovery. His research employs large-scale prospective cohort methodologies for clinical work and molecular/cellular approaches for basic science investigations. The work has been widely disseminated, with multiple articles receiving substantial attention across academic and public platforms. Dr. Richardson collaborates extensively across UK institutions as part of multi-center research efforts, particularly through the PHOSP-COVID consortium, which has produced several high-impact publications analyzing different aspects of post-hospitalization recovery from COVID-19.

• Cancer Cachexia
• Immunology
• Nutritional Intervention
• +5 more

Dr. Klaske van Norren is an Associate Professor in Nutritional Biology at Wageningen University. Her research focuses on cancer cachexia, immune modulation via dietary components, and the interplay between exercise, nutrition, and inflammation. She leads projects investigating tumor-induced muscle wasting, nutritional interventions for pulmonary hypertension, and the effects of bioactive compounds (e.g., β-glucan, arabinoxylan) on immune resilience. She co-supervised six PhD candidates, including studies on fatigue, cachexia, and intestinal permeability. Her work integrates mouse models, cellular co-cultures, and clinical datasets to explore mechanisms linking nutrition, immunity, and chronic disease. Key research themes: Cancer cachexia, trained immunity, exercise immunology, dietary fiber effects Publications span immunology, nutrition, and oncology journals Collaborations include studies on cytokine signaling, hypothalamic inflammation, and mitochondrial dysfunction in muscle wasting

• Metabolic Disorders
• Endocrinology
• Diabetes Research
• +5 more

Jianying Dong is an Associate Research Scientist in the Department of Endocrinology at Yale School of Medicine, Yale University. Her research focuses on metabolic disorders, insulin resistance, and molecular mechanisms underlying energy homeostasis. She collaborates with prominent researchers like Gerald I. Shulman, investigating topics such as leptin signaling, mitochondrial function, and dietary-induced metabolic changes. Key contributions include studies on the role of mitochondrial enzymes in gluconeogenesis and the impact of genetic deficiencies on obesity and insulin sensitivity. Her work employs mouse models to explore pathways related to fatty acid metabolism, gut-derived signaling molecules, and aging effects on metabolic processes. Notable publications address leptin’s role in body temperature regulation, mitochondrial dysfunction in liver steatosis, and the protective effects of n-3 fatty acids against insulin resistance. Dong’s interdisciplinary approach bridges endocrinology, molecular biology, and physiology, contributing to advancements in diabetes and metabolic disease research.

• Neuroscience
• Cell Biology
• Virology
• +3 more

Jacob Stagray is a Research Fellow in the Department of Neuroscience at the Yale School of Medicine, Yale University. His work bridges neurobiology and infectious disease research, focusing on cellular mechanisms in neuroendocrine systems and vaccine development against viral pathogens. Research Interests include the role of tanycytes in hypothalamic signaling, FGF receptor pathways, and dietary impacts on cellular proliferation. In virology, he explores HSV-2 vaccine efficacy across species models, contributing to advancements in antiviral strategies. No awards or grants are explicitly listed in the provided materials. No advisees or lab affiliations are detailed, but his recent publications span 2017–2024 with a focus on translational biomedical research.

• Hypothalamic Regulation
• Obesity
• Dopamine Receptors
• +3 more

Michael Rubinstein is an Assistant Clinical Professor in the Department of Digestive Diseases and Internal Medicine at Yale School of Medicine. His research focuses on neuroendocrinology, molecular biology, and genetic mechanisms underlying obesity, hypothalamic regulation, and dopamine receptor function. He has contributed to studies on human accelerated regions in gene evolution, hypothalamic POMC regulation, and dopamine receptor effects in behavior and physiology. Education: MD from Stony Brook University (1989). Research Interests: Gene expression regulation in neuroendocrine pathways Molecular mechanisms of obesity and food intake control Evolutionary genomics of human-specific traits Dopamine receptor signaling in behavior and metabolism Recent publications highlight his work on human accelerated regions (HAR202), Six3 transcription factors, and tripartite enhancer clusters controlling POMC expression. No scientific awards explicitly listed in provided text. No advising/grant details or lab affiliations described in current data.

• Metabolism
• Immunology
• Metabolic Networks
• +3 more

Qiushi Sun is an Associate Research Scientist at Yale University’s Yale School of Medicine, primarily affiliated with the Department of Endocrinology. His research focuses on metabolic networks, immunometabolism, and the application of advanced metabolomics techniques such as stable isotope-resolved metabolomics (SIRM). He investigates metabolic pathways in diseases like cancer, neurodegeneration, and inflammatory conditions, with a particular emphasis on environmental and toxicological impacts on metabolism. Dr. Sun’s work integrates cutting-edge analytical chemistry methods, including ion chromatography and ultra-high-resolution mass spectrometry, to map metabolic networks and study drug resistance mechanisms. His contributions include elucidating the role of inosine in T-cell function under glucose deprivation and exploring how air pollution disrupts hepatic metabolism. He collaborates with the Kibbey Lab, advancing interdisciplinary research at the intersection of metabolism, immunology, and environmental health. Key areas of research include metabolic profiling of oncological disorders (e.g., multiple myeloma), redox signaling in neurons, and the metabolic consequences of gene mutations in neurodegenerative diseases. His methodologies have been applied to 3D tumor spheroid models and non-invasive mouse studies, enhancing our understanding of disease mechanisms and potential therapeutic targets. Dr. Sun’s expertise spans metabolic pathway analysis, stable isotope tracing, and the development of novel analytical tools for metabolomics. His findings have implications for personalized medicine, environmental health policies, and immunotherapy strategies.

• Bone Biology
• Endocrinology
• Molecular Biology
• +3 more

Gang-Qing Yao is a Senior Research Scientist in Endocrinology at Yale School of Medicine. He holds affiliations with the Department of Internal Medicine and the Insogna Lab. His research focuses on bone biology, parathyroid hormone (PTH) signaling, osteoclastogenesis, and molecular mechanisms regulating bone metabolism. Key areas include the role of CSF-1 isoforms, sphingosine kinase-2 (SK2), and RANKL mRNA stability in bone remodeling. Education: MD (Gannan Medical University, 1981), Postdoctoral Fellowship (Chinese Academy of Medical Sciences, 1987). Awards include the Featured Investigator Pilot Award (Yale SOM, 1999) and the Junior Investigator Award (Chinese Academy of Medical Sciences, 1988). His work spans over 30 peer-reviewed publications, with recent studies on PTH-dependent RANKL regulation and CSF production in mice. He has presented at ASBMR Annual Meetings and collaborates with experts like Karl Insogna and Steven Tommasini. Research highlights include discovering SK2’s role in bone anabolism and identifying critical cis-elements in SPHK1 gene regulation.

• Neuroendocrinology
• Metabolic Pathways
• Neuroimmunology
• +3 more

Yuki Yasumoto is an Associate Research Scientist in the Department of Comparative Medicine at Yale School of Medicine. Her research focuses on neuroendocrine regulation of homeostasis, glial cell biology, and lipid metabolic pathways in health and disease. She investigates how glial cell metabolism influences systemic metabolic processes and contributes to disorders such as ataxia and neuroinflammation. Her work integrates virology, cell biology, and neuroscience, with notable studies on SARS-CoV-2 neuroinvasion, placental infection, and the effects of ketogenic diets on aging-related viral susceptibility. Key collaborators include Tamas Horvath (Neuroscience), Akiko Iwasaki (Virology), and Craig Wilen (Microbiology). Yasumoto’s research has been published in high-impact journals such as Neuron , Cell , and Molecular Psychiatry . Her lab explores interdisciplinary approaches to understand the interplay between glial cells, metabolic pathways, and neurological diseases. Current studies focus on lipid dynamics in astrocytes and their role in neurodegenerative conditions.

• Neurobiology
• Energy Balance Regulation
• Sleep/Wake Cycles
• +3 more

Xiao-Bing Gao is a Senior Research Scientist in the Department of Comparative Medicine at the Yale School of Medicine. His research focuses on understanding how neural circuits in the lateral hypothalamus regulate energy balance, sleep/wake cycles, addiction, and obesity. He holds appointments in the Yale Center for Molecular and Systems Metabolism and collaborates with prominent researchers like Tamas Horvath and Hugh Taylor. Research Interests Neuronal plasticity in hypocretin/orexin and melanin-concentrating hormone systems Neurobiological mechanisms of addiction and reward-seeking behavior Interactions between metabolic state and sleep regulation Developmental effects of early environmental influences on hypothalamic circuitry Grants & Awards NIH/NIDA-funded study on hypocretin control of cocaine addiction NIH/NIDDK project investigating MCH-neuron interactions in feeding behavior Mentored Research Scientist Development Award (NIH) American Heart Association Scientist Development Grant Key Collaborations Tamas Horvath (Yale) Zhongwu Liu (Yale) Hugh Taylor (Yale) Marina Picciotto (Yale)