Sonia MayoralView profile
Assistant Professor
Sonia Mayoral is the Robert J. and Nancy D. Carney Assistant Professor of Neuroscience at Brown University. Her research focuses on studying cell-cell interactions in the brain, particularly the development and function of oligodendrocytes – glial cells critical for myelin formation. She explores how these cells contribute to myelination, remyelination processes, and their roles in neurological disorders like multiple sclerosis. Her work integrates cellular neuroscience, immunology, and drug screening methodologies. Research interests include glial cell biology, neuron-glial interactions, and the molecular mechanisms governing myelin repair. She investigates how environmental cues and signaling pathways regulate oligodendrocyte differentiation and function. Notable projects involve developing high-throughput screening platforms for MS therapeutics and studying sex-specific responses to neurodegenerative challenges. Her lab’s recent work includes clinical trials (Re-WRAP) evaluating Bazedoxifene for remyelination in women, and fundamental studies on regulatory T cell roles in myelin regeneration. She also examines how mechanical stimulation and epigenetic changes influence oligodendrocyte behavior. Her research bridges basic science and translational efforts, aiming to advance treatments for myelin-related disorders. Dr. Mayoral’s lab is active at Brown University, with a dedicated website detailing ongoing projects and collaborations. While no specific grants or students are listed here, her work reflects a strong focus on interdisciplinary approaches to neurodegenerative disease mechanisms.










