Kathrin Lang is a Full Professor at the Department of Chemistry and Applied Biosciences, ETH Zurich, and Head of the Organic Chemistry Laboratory. Her research focuses on chemical biology, particularly the development of tools for genetic code expansion to incorporate non-canonical amino acids into proteins and advance bioorthogonal chemistries for studying biological processes. Keywords: Genetic Code Expansion, Bioorthogonal Chemistry, Protein Engineering, Ubiquitylation Networks, Post-Translational Modifications. Lang’s work emphasizes proximity-triggered crosslinking reactions, bioorthogonal labeling, and in vivo chemistries to address challenges in protein interaction mapping and structural elucidation. Her group’s recent publications highlight methodologies for dual protein labeling, deciphering ubiquitin code, and enhancing cycloaddition reactivity. Current projects include exploring cyclopropene-fused dibenzocyclooctynes for improved labeling and investigating methylated lysine as a conformational regulator in Hsp90. Funding sources include the ERC (Ubl-tool), DFG (SFB1035, SPP1926), and ETH Zurich. She contributes to education through courses like Genetic Code Expansion for Studying Posttranslational Modifications and Chemical Biology and Synthetic Biochemistry . Collaborative efforts span structural biology, microbiology, and synthetic biochemistry, with applications in ubiquitin research and cellular imaging.
Tom Ian Battin is a Full Professor at the École Polytechnique Fédérale de Lausanne (EPFL), affiliated with the School of Architecture, Civil and Environmental Engineering (ENAC). He holds roles in three departments: the River Ecosystems Research Laboratory (RIVER), the Laboratory of Management of Infrastructures, Networks and Construction (LIMNC-GE), and the SSIE Teaching Unit (ENS). His research focuses on aquatic ecosystems, microbial communities in glacier-fed streams, climate change impacts, and biogeochemical processes in alpine environments. He advises numerous doctoral students and has supervised over ten theses at EPFL. Battin teaches courses such as 'Fundamentals in Ecology,' 'Aquatic Ecosystems,' and 'Global Change Ecology and Fluvial Ecosystems.' He is actively involved in academic governance, serving on the EPFL Academic Strategic Committee (ASC) and the ENAC Academic Evaluation Committee (CEA). His work investigates how glacier retreat affects stream microbiomes, dissolved organic carbon dynamics, and ecosystem resilience. Key themes include microbial metabolism, biofilm functionality, and the interplay between hydrology and biogeochemistry. Battin leads research projects on global glacier-fed stream biogeography and the resistome of stream biofilms. His interdisciplinary approach bridges ecology, microbiology, and environmental engineering, addressing critical questions about mountain ecosystems under climate change.
Dr. Jacques Archambault is a Professor in the Department of Microbiology and Immunology at McGill University , and an associate member of the Division of Experimental Medicine since 2016. His research focuses on the molecular biology and pathogenesis of human papillomaviruses (HPVs) and polyomaviruses (HPyVs), with an emphasis on their replication mechanisms as episomes in host cells. The Archambault laboratory employs functional genomics, proteomics, and chemical biology approaches to identify cellular pathways exploited by these viruses and develop high-throughput assays for screening small molecule inhibitors of viral replication. Analysis of his recent publications reveals a strong focus on HPV and HPyV replication machinery, including studies on the E1 helicase, UAF1-USP1 interactions, and structural characterization of viral proteins involved in DNA replication. His work bridges virology, oncology, and drug discovery, particularly targeting oncogenic HPV types implicated in anogenital and oropharyngeal cancers, as well as HPyVs like BKPyV and JCPyV that cause pathologies in immunosuppressed patients. Current efforts in the lab aim to elucidate the molecular mechanisms by which HPVs and HPyVs replicate their genomes and to develop antiviral therapies targeting these processes. Techniques such as fluorescence anisotropy, NMR spectroscopy, and crystallography are frequently employed to study protein-DNA and protein-protein interactions critical to viral replication.
Dr. John M. Ruter is the Allan M. Armitage Professor and Director of the UGA Trial Gardens within the College of Agricultural & Environmental Sciences at the University of Georgia. His work integrates plant breeding, genetics, and sustainable nursery crop production, focusing on ornamental plants for southeastern landscapes. Education: B.S. in Ornamental Horticulture, California Polytechnic State University (1984) M.S. in Ornamental Horticulture and Landscape Design, University of Tennessee (1986) Ph.D. in Horticultural Science, University of Florida (1989) Research interests include developing climate-resilient ornamental plants (e.g., Camellia oleifera , hibiscus, crape myrtle), mutation breeding via gamma irradiation, and optimizing nursery production systems. Recent projects focus on polyploid conifer evaluation and tea oil crop development for the southeastern U.S. Recent publications highlight advancements in induced mutagenesis (EMS, gamma irradiation), disease resistance screening (Cercospora leaf spot), and genetic characterization of native and ornamental species. Key subfields include ornamental breeding , genomic analysis , and sustainable production practices . As Director of the UGA Trial Gardens, he leads plant evaluation programs that inform regional landscaping decisions and cultivar development.
Anna Salvati is an Associate Professor specializing in nanomedicine and drug delivery systems. Her research focuses on nanoparticle-cell interactions, biomolecular corona formation, and the physicochemical properties governing nanomaterial behavior in biological environments. Key research themes include cellular uptake mechanisms, toxicity of nanomaterials, and nanoparticle targeting strategies. Recent publications highlight her work on nanoparticle stability, membrane interactions, and environmental impacts of microplastics. Her studies integrate multiomics approaches, advanced imaging, and interlaboratory validation to address challenges in nanomedicine design and safety testing. Current projects explore the role of high-density lipoproteins in nanoparticle functionality and the modulation of drug release kinetics through material engineering.
Pamela Ronald is a Distinguished Professor of Plant Pathology at the University of California, Davis, affiliated with the Department of Plant Pathology within the College of Agricultural and Environmental Sciences. Her research focuses on understanding and enhancing crop resilience, particularly in rice, through genetic and molecular mechanisms. Key areas include plant immunity against pathogens, climate adaptation, and sustainable agricultural practices. Education and Background: Details on her academic qualifications are not explicitly mentioned in the provided text, but her career trajectory suggests advanced training in plant genetics and pathology. Research Interests: Ronald’s work centers on engineering disease-resistant crops, studying plant-microbe interactions, and developing climate-resilient varieties. Notably, she has contributed to identifying genes like XA21 that confer resistance to bacterial infections and pioneered methods to reduce methane emissions in rice. Her studies also explore the role of sulfated peptides in pathogen virulence and host defense mechanisms. Publications Trends: Her recent articles emphasize molecular mechanisms of plant immunity, genetic engineering applications, and sustainability challenges. Themes include directed evolution of immune receptors, machine learning in genotype-phenotype prediction, and mitigation of agricultural greenhouse gases. Awards and Recognition: While specific awards are not listed here, her leadership in plant genetics and advocacy for evidence-based biotechnology policies reflect significant recognition in her field. Grants and Advising: Ronald has led projects funded by agencies like the U.S. Department of Energy, focusing on bioenergy crops like switchgrass. She collaborates globally on initiatives such as the Rice Protein Tagging Project and the AI Institute for Next Generation Food Systems. Labs and Teams: She directs the Crop Genetics Innovation Lab at UC Davis, fostering interdisciplinary research in crop improvement and sustainable agriculture.
James Shorter is a Professor of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania. He is affiliated with multiple prestigious institutes, including the Institute on Aging (IOA), the Institute for Translational Medicine and Therapeutics (ITMAT), the Penn Center for AIDS Research (CFAR), the Chemistry-Biology Interface (CBI), and the Penn Institute for RNA Innovation. He mentors several training programs such as the Penn Summer Undergraduate Internship Program (SUIP), PennPREP, and the Translational Research Immersion Program (TRIP), and serves as a Primary Trainer at the Center for Neurodegenerative Research (CNDR). Ph.D. in Cell Biology, University of London, 2000 M.A. in Biology, University of Oxford, 1995 Dr. Shorter’s research focuses on protein homeostasis, particularly the mechanisms of protein disaggregation and the role of prion-like domains in neurodegenerative diseases such as ALS, Alzheimer’s, Parkinson’s, and frontotemporal lobar degeneration. His lab investigates the Hsp104 disaggregase from yeast and has engineered variants to combat human proteinopathies. They also identified the mammalian disaggregase system (Hsp110/Hsp70/Hsp40) and explore how small molecules and nuclear import receptors can reverse pathological phase transitions of RNA-binding proteins like TDP-43 and FUS. His work bridges structural biology, genetics, and translational neuroscience. His recent publications highlight trends in targeting TDP-43 and FUS proteinopathies, engineering Hsp104 for selective detoxification, understanding mitochondrial disaggregases like Skd3, and modulating phase transitions with nuclear import receptors. His research spans from fundamental mechanisms of protein folding to therapeutic development for neurodegenerative diseases. Faculty Member, Institute on Aging (IOA) Faculty Member, Institute for Translational Medicine and Therapeutics (ITMAT) Mentor, Penn Summer Undergraduate Internship Program (SUIP) Primary Trainer, Center for Neurodegenerative Research (CNDR) Faculty Member, Penn Center for AIDS Research (CFAR) Member, Penn Institute for RNA Innovation Mentor, Translational Research Immersion Program (TRIP) Dr. Shorter advises numerous graduate students and postdoctoral researchers through the Biochemistry and Molecular Biophysics, Pharmacology, Neuroscience, and Cell and Molecular Biology graduate groups. His lab receives funding from NIH and other sources to support research on protein disaggregation, phase separation, and neurodegenerative disease mechanisms. He has trained many scientists now active in academia and biotech. His lab, located in Stellar-Chance Laboratories, operates at the intersection of biochemistry, cell biology, and translational medicine, with active projects on Hsp104 engineering, mitochondrial proteostasis, and the role of RNA-binding proteins in disease. The lab collaborates widely across Penn and with international partners to advance understanding and treatment of protein misfolding disorders.
Dr. Xi Chen is a Professor in the Department of Chemistry at the University of California, Davis, where he has been a faculty member since 2003. His research spans carbohydrate chemistry, glycobiology, and cancer biology, with notable contributions to chemoenzymatic methods for glycoconjugate synthesis. Dr. Chen's work focuses on developing hybrid chemical-enzymatic approaches to synthesize complex carbohydrates and glycoconjugates, characterizing glycosyltransferase mechanisms, and designing enzyme mutants for improved catalysis. He also investigates carbohydrate-based diagnostics and therapeutics, particularly in cancer and inflammatory diseases. His recent publications highlight interdisciplinary studies linking carbohydrate metabolism to p53 tumor suppression pathways and RNA-binding protein regulation in cancer. Awards include AAAS Fellow (2015), ACS Isbell Award (2012), and NSF CAREER Award (2006). He earned his Ph.D. at Wayne State University (2000) and B.S. at Xiamen University (1994). Scientific Awards American Association for the Advancement of Science Fellow (2015) Dean's Team Award for Excellence (2013) Carbohydrate Research Award for Creativity (2013) ACS CARB Horace S. Isbell Award (2012)
Dr. Vadim Backman is the Sachs Family Professor of Biomedical Engineering and Medicine at Northwestern University's McCormick School of Engineering and Applied Sciences and Feinberg School of Medicine. He holds additional roles as Professor of Medicine (Hematology/Oncology) and Biochemistry and Molecular Genetics, Associate Director of Research Technology and Infrastructure at the Robert H. Lurie Comprehensive Cancer Center, and Director of the Center for Physical Genomics and Engineering. He earned his Ph.D. in Medical Engineering from Harvard-MIT and M.S./B.S. in Physics from St. Petersburg Polytechnic Institute. His research focuses on physical and biological science intersections, developing nanoscale imaging and computational technologies to study chromatin dynamics and their role in disease. Key areas include cancer diagnostics/therapeutics, chromatin engineering, and genome nanoimaging. Dr. Backman has published over 230 papers, holds 20+ patents, and leads large-scale projects like NCI Bioengineering Research Partnerships. Education: Ph.D. (Harvard-MIT), M.S. (MIT), M.S./B.S. (St. Petersburg Polytechnic Institute) Affiliations: PhD Programs in Applied Physics and Interdisciplinary Biological Sciences Research emphasizes chromatin's role in disease, with clinical translation for diagnostics and therapy. His lab develops technologies like nano-CHIA and ChromSTEM, advancing understanding of genomic organization and epigenetic regulation. Awards include the Cozzarelli Prize and MIT Technology Review's Top 100 Innovators. Awards: Cozzarelli Prize (2017), AIMBE Fellowship (2009), NSF CAREER Award (2003) Grants and collaborations include managing multi-investigator projects and co-founding biotech companies. Courses taught: BME 302 (Quantitative Systems Physiology), BME 429 (Advanced Physical and Applied Optics).
Dr. Matthew Kimber is a Professor in the Department of Molecular and Cellular Biology at the University of Guelph. His research focuses on structural biology of bacterial systems, particularly bacterial polysaccharides and microcompartments. He employs x-ray crystallography to study molecular architectures, with current projects exploring mechanisms of bacterial surface polysaccharide assembly and bacterial microcompartment function. Education: B.Sc. (Hons) Molecular Genetics and Molecular Cell Biology from the University of Toronto (1993), Ph.D. in Molecular and Medical Genetics from the University of Toronto (2000). Research Interests: Structural basis of polysaccharide assembly and modification, bacterial microcompartment structure-function relationships, and enzyme mechanisms. Key projects include studies on glycosyltransferases, carboxysomes, and aminoacetone degradation pathways. Lab Members: Current graduate students include Laura Seidel, Liam Noseworthy, Manitabhai Govind, and Shaoqian Zong. Former members include Patrick Ryan, Evan Mallette, and Tom Keeling. Lab Focus: Probing structural details of biological molecules to understand function, with emphasis on bacteria’s strategies for polysaccharide modification and microcompartment assembly. Recent work includes characterization of enzymes involved in O-antigen biosynthesis and microcompartment shell proteins.
Kristina Schoonjans is an Associate Professor at EPFL’s School of Life Sciences, where she leads the Laboratory of Metabolic Signaling (UPSCHOONJANS). Her research focuses on the molecular mechanisms of bile acid signaling, nutrient sensing, and intermediary metabolism, particularly in the context of metabolic disorders such as obesity, fatty liver disease, and cancer. She investigates how the liver-gut-brain axis integrates metabolic signals through nuclear receptors and mitochondrial dynamics. Her research interests include: Bile acid signaling and its role as a hormonal regulator Nutrient and metabolite sensing in energy homeostasis Intermediary metabolism and metabolic disorders Role of nuclear receptors (e.g., TGR5, LRH-1) in liver, gut, and adipose tissue Mitochondrial dynamics and fission in metabolic regulation Organoid models for studying liver and intestinal metabolism Systems genetics using BXD mouse populations The most recent articles highlight a strong focus on bile acid signaling, particularly through TGR5 and LRH-1, in regulating metabolic health. Themes include the conversion of white fat to beige fat (beiging), hepatic tumorigenesis, mitochondrial fission, and the use of organoid and genetically engineered mouse models. There is a consistent emphasis on translational applications for obesity, fatty liver disease, and cancer. Scientific honors include: Windaus Prize from the Dr. Falk Foundation (2010, shared with Johan Auwerx) for the discovery of the signaling/endocrine function of bile acids Prof. Schoonjans actively supervises PhD students and has advised numerous doctoral candidates who have since completed their theses. Her lab is supported by multiple grants from Swiss and international funding agencies, including the Swiss National Science Foundation, EPFL, CONACYT, and the Foundation for Health and Education. She teaches in several doctoral programs at EPFL, including Life Sciences Engineering, and contributes to education through the SSV and EDBB/EDCB/EDMS-ENS programs. The Schoonjans Lab brings together scientists, doctoral assistants, and technicians working on projects related to metabolic signaling. The team uses advanced techniques such as genetically modified mouse models, organoid cultures, and multi-omics (metabolomics, proteomics, transcriptomics) to study the liver-gut and brain-liver axes. The lab has a strong track record of high-impact publications and collaborations with institutions worldwide.
Ramesh Shanmughom Pillai is a Full Professor at the Department of Molecular Biology, University of Geneva, Switzerland. He holds additional roles as a Visiting Professor at the University of Kumamoto, Japan, and has been a Group Leader at EMBL Grenoble and a postdoctoral fellow at the Friedrich Miescher Institute. His research focuses on RNA modifications, epigenetics, and piRNA pathways in germline biology. Pillai has received prestigious awards including the ERC Consolidator Grant and The RNA Society Scaringe Award. Education: BSc Botany (University of Kerala, India) MSc Biotechnology (IIT Roorkee, India) PhD in Cell Biology (University of Bern, Switzerland) Research Interests: Pillai’s work centers on RNA biology, particularly the role of RNA modifications (e.g., m6A, m6Am) in development and fertility. He investigates piRNA biogenesis, transposon silencing, and the molecular mechanisms of RNA-protein interactions. His studies bridge biochemistry, genetics, and structural biology to elucidate how RNA molecules regulate critical biological processes. Teaching & Service: At the University of Geneva, he teaches Molecular Biology courses (BSc/MSc levels) and advises 5 PhD students and 4 postdocs. He chairs the ERC Consolidator Grant Review Panel and organizes major conferences like the PIWI/piRNAs Meeting and Swiss RNA Workshop. Pillai also serves on editorial boards for Nucleic Acids Research and RNA . Awards: ERC Consolidator Grant (2015) Best PhD Thesis Award (2003) RNA Society Scaringe Award (2005) Grants & Labs: Funded by ERC Starting and Consolidator Grants, his lab explores RNA modification networks in germ cells. Former trainees include Professors Simon Conn (Flinders University) and Hao Wu (CAS, China).
Prof. Ilse Dewachter is the head of the Biomed Neuroscience research group at Hasselt University (UHasselt), specializing in Alzheimer’s therapy and prevention for over 25 years. Her work focuses on multi-targeted therapies targeting tau, inflammation, and ApoE, alongside pioneering research into disease prevention via blood-based biomarkers. Recent studies explore a protective APOE3ch mutation that halted Alzheimer’s progression in a patient, offering hope for new treatments. Research Interests: - Alzheimer’s disease mechanisms (Abeta, tau, inflammation) - Multi-target therapies and biomarker development - Neurodegenerative disease prevention strategies - Genetic mutations impacting disease progression Articles Overview: Her most recent work (2025-2022) addresses neuroinflammation, tau propagation models, and AI-driven neuroimaging. Key themes include APOE genetics, blood-brain barrier dynamics, and exercise impacts on cognition. Funding & Grants: Current projects require significant investment for advanced biomarker equipment and clinical trials. A notable €300,000 grant funded research on brain lipid metabolism’s role in Alzheimer’s. Labs & Teams: Leads the BIOMED Neuroscience group at UHasselt, collaborating internationally on preclinical models and drug development.
Dr. Zhiwen Jonathan Zhang serves as Associate Professor in the Department of Bioengineering at Santa Clara University's School of Engineering since 2011, with research spanning biomolecular engineering, drug discovery, and BIOAI to combat super-bacterial infections and advance precision protein technologies. Education: Ph.D. in Chemistry and Biochemistry, University of Texas at Austin (2001) Postdoctoral Research, The Scripps Research Institute (2001-2004) His interdisciplinary research pioneers unnatural genetic codes, trM2H systems, site-specific protein cross-linking, and synthetic antibodies. Current focus includes mitochondrial peptide transport, BIOAI design, subcellular protein synthesis, and engineering bacteria for micro-plastics degradation. His lab unraveled molecular dialogues between mammalian and Gram-positive bacterial cells, enabling groundbreaking anti-infective therapies. Publication trends reveal consistent innovation in protein engineering and translational bioengineering, with recent work emphasizing sortase A applications, fluorescent peptide development, and unnatural amino acid incorporation in mammalian systems—demonstrating a trajectory from fundamental biochemistry to industry-ready biotech platforms. Dr. Zhang has mentored 7 post-doctoral researchers, 2 visiting professors, and 5 Ph.D. students while securing grants from NIH NCI R01, NSF SBIR, American Heart Association, Welch Foundation, JOINN Foundation, IBM, and SCU Internal Research. His patented "Biotech+Techbio" platform has co-founded multiple biotech ventures, including two publicly traded companies and a 2024 acquisition. His laboratory maintains active collaborations with Bay Area biotech firms and academic institutions, driving translational research through the patented Biotech+Techbio platform while advancing BIOAI-assisted enzyme discovery for micro-plastics degradation and next-generation antibacterial therapies.
Georg Fantner is an Associate Professor at the Swiss Federal Institute of Technology Lausanne (EPFL) with dual appointments in the School of Engineering (STI) within the Institute of Bioengineering and the School of Life Sciences (SV) for teaching. He directs the Laboratory for Bio- and Nano-Instrumentation (LBNI) and holds leadership roles including President of the Open Science Strategic Committee and the Association des Professeurs de l'EPFL. Research Focus: Bioinstrumentation, Nanotechnology, Scanning Probe Microscopy, and Metrology Teaching: Structural Mechanics for Life Sciences, Metrology, and Metrology Practicals His research pioneers advanced instrumentation for nanoscale characterization, emphasizing data-driven approaches to enhance microscopy techniques. Recent work integrates deep learning with scanning probe microscopy for real-time biological imaging and develops novel MEMS devices for fluid-compatible nanoscale manipulation. Key innovations include hermetically sealed sample chambers for pathogen studies and deterministic nanotopography engineering. Professor Fantner actively mentors 7 current PhD students and has supervised 14 graduates. His laboratory fosters interdisciplinary collaboration across engineering, physics, and life sciences to advance nanoscale measurement technologies and instrumentation development.
