Lihua Julie ZhuView profile
Professor
Lihua Julie Zhu is a Professor and the head of Bioinformatics Core in the Department of Molecular, Cell and Cancer Biology at UMass Chan Medical School (UMMS). She also holds positions in the T.H. Chan School of Medicine, Program in Molecular Medicine, Interdisciplinary Graduate Program, and Bioinformatics and Integrative Biology program. With an interdisciplinary background spanning nutritional sciences and computer science, Dr. Zhu leads a research program focused on computational biology and bioinformatics methodologies for genomic data analysis. Dr. Zhu's educational background includes: BS in Animal Nutrition from China Agricultural University, Beijing MS in Animal Nutrition from China Agricultural University, Beijing MS in Computer Science from DePaul University, Chicago PhD in Nutritional Sciences from University of Wisconsin-Madison Dr. Zhu's research focuses on understanding gene regulation and cancer etiology through the development and application of computational tools for analyzing high-throughput genomic datasets. Her lab specializes in mining and integrating various genomic technologies including WGS, ChIP-seq, bulk and single cell RNA-seq, and ATAC-seq. A key strength of her research program is algorithm development, with her team having created over 20 computational tools, including numerous Bioconductor packages that serve the broader research community. Analysis of Dr. Zhu's recent publications (2024-2025) reveals a strong emphasis on both methodological innovation and biological discovery. Her work spans cancer biology, genome editing technologies, and computational tool development across multiple biological systems. A significant portion of her recent publications involve the creation of specialized bioinformatics tools for analyzing complex genomic datasets, demonstrating her dual commitment to advancing computational methodology while making biological discoveries. Dr. Zhu leads the Bioinformatics Core facility at UMass Chan Medical School, providing essential computational expertise and support to researchers across the institution. The core facility plays a critical role in enabling sophisticated genomic analyses for numerous research projects requiring advanced computational approaches to analyze complex biological data.











