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Hang LuView profile

Professor

• Microfluidics
• Systems Biology
• Neuroscience
• +6 more

Hang Lu is a Professor and holds the Cecil J. "Pete" Silas Chair of Chemical & Biomolecular Engineering at the Georgia Institute of Technology. Dr. Lu also holds a Love Family Professorship and leads the Lµ Fluidics Group, which focuses on engineering microfluidic systems and machine learning tools to address complex questions in neuroscience, developmental biology, and cell biology that are difficult to address with conventional techniques. Dr. Lu's research lies at the intersection of engineering and biology, with primary interests including: Microfluidic systems for high-throughput screens and image-based genetics and genomics Systems biology: large-scale experimentation and data mining Microtechnologies for optical stimulation and optical recording Big data, machine vision, and automation Developmental neurobiology, behavioral neurobiology, and systems neuroscience Cancer biology, immunology, embryonic development, and stem cells Her laboratory engineers microfluidic devices and BioMEMS to study neuroscience, genetics, cancer biology, and biotechnology. These miniaturized Lab-on-a-chip tools operate at scales comparable to biological systems, leveraging unique micro and nano-scale phenomena to gather large-scale quantitative data about complex biological systems. Current projects include Microfluidics for Life Sciences, Optical Neuron Recordings and Manipulations, Machine Learning Tools for Neuroscience, Measuring and Modeling Behavior, and High-throughput, High-content Cell-based Assays. Analysis of Dr. Lu's recent publications (2024-2025) reveals a strong trend toward integrating microfluidics with advanced computational methods: Development of deep learning frameworks for biological image analysis Advanced neuron tracking and functional imaging techniques Non-invasive characterization of 3D organoid cultures Sophisticated neuromechanical modeling of locomotion Microfluidic temperature control systems for in vivo studies Label-free imaging pipelines for neural development Dr. Lu's significant professional honors include: Cecil J. "Pete" Silas Chair of Chemical & Biomolecular Engineering Love Family Professorship The Lµ Fluidics Group actively mentors students and postdocs, currently accepting new postdoctoral researchers. The lab receives substantial funding for interdisciplinary projects at the engineering-biology interface, with research implications spanning fundamental biological understanding to therapeutic development. The group operates within Georgia Tech's School of Chemical & Biomolecular Engineering, with specialized facilities for microfluidic device fabrication, biological experimentation, and advanced imaging, maintaining strong collaborative ties across engineering, neuroscience, and biological disciplines.

James BriscoeView profile

Professor

• Developmental Biology
• Molecular Signaling
• Transcriptional Networks
• +4 more

James Briscoe is a Senior Group Leader at The Francis Crick Institute in London, where he leads a research group focused on developmental biology and morphogen signaling. He previously held positions at the Medical Research Council's National Institute for Medical Research, which later became part of the Francis Crick Institute. Education: BSc in Microbiology and Virology from the University of Warwick, UK PhD from Imperial Cancer Research Fund/King's College London Postdoctoral training at Columbia University with Thomas Jessell Dr. Briscoe's research focuses on the molecular and cellular mechanisms of graded signaling by morphogens and the role of transcriptional networks in cell fate specification. His laboratory employs a range of experimental and computational techniques using model systems including mouse and chick embryos and embryonic stem cells. His work has significant implications for understanding developmental processes and their relationship to disease. His recent publications demonstrate a continued focus on morphogen gradients, neural tube development, and computational approaches to understanding cell fate decisions. His research increasingly integrates single-cell technologies and computational modeling to unravel the complexities of developmental patterning. Scientific Awards and Honors: EMBO Young Investigator (2001) EMBO Gold Medal (2008) Elected to EMBO (2009) Fellow of the Academy of Medical Sciences (2019) Fellow of the Royal Society (2019) As Editor-in-Chief of the journal Development since 2018, Dr. Briscoe plays a significant role in shaping the field of developmental biology. His leadership extends to mentoring researchers and contributing to scientific policy discussions, as evidenced by his recent publication 'Science under siege: protecting scientific progress in turbulent times.' Dr. Briscoe's laboratory at the Crick Institute is well-equipped with access to advanced facilities including light microscopy, flow cytometry, genomics, and computational resources, enabling a multidisciplinary approach to developmental biology questions.

Waldemar KolanusView profile

Professor

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +4 more

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

Omer BayraktarView profile

Researcher

• Neural Diversity
• Spatial Transcriptomics
• Glia Biology
• +3 more

Omer Bayraktar is a Group Leader at the Wellcome Sanger Institute , leading research in the Cellular Genomics Programme. His work focuses on decoding human brain cellular diversity using spatial transcriptomics , imaging , and functional screening to study neural complexity in health and disease. Bayraktar's educational background includes a PhD from HHMI under Chris Doe, investigating neural diversity development in Drosophila , followed by postdoctoral work at University of California, San Francisco and University of Cambridge as a Life Sciences Research Foundation Fellow. He developed a spatial transcriptomic pipeline during his postdoc to analyze astrocyte heterogeneity in the cerebral cortex. His research explores neural cell type mapping , glial-neuronal interactions , and cellular pathways in neurodevelopmental disorders . Recent publications emphasize 3D tissue mapping , multi-omic integration , and computational tools like Cell2fate and WebAtlas. His work bridges neurogenetics and computational biology to advance understanding of human tissue ecosystems. Bayraktar's lab collaborates with the Human Cell Atlas initiative and develops technologies such as automated histology pipelines and highly-multiplexed smFISH for molecular cell typing. His team also investigates glia-based therapies and astrocyte functional heterogeneity in neurodevelopmental contexts. Key scientific contributions include: Discovering astrocyte layer patterns independent of neuronal laminae Developing cell2location for spatial cell mapping Characterizing Drosophila neural stem cell models with human relevance Notable awards include the Life Sciences Research Foundation Fellowship during his postdoctoral training. His current group includes a PhD student , Senior Data Scientists , and Bioinformaticians .

Julia KamenzView profile

Assistant Professor

• Cell cycle regulation
• Cell division
• Biochemistry
• +7 more

Dr. Julia Kamenz is an Assistant Professor (Rosalind Franklin fellow) at the University of Groningen's Faculty of Science and Engineering, where she leads research in the Molecular Systems Biology group within the Groningen Biomolecular Sciences and Biotechnology Institute (GBB). Her work focuses on understanding the molecular mechanisms that regulate cell cycle progression and cell division. Dr. Kamenz received her undergraduate training in Biochemistry at the University of Tuebingen, completed her PhD at the Friedrich Miescher Laboratory of the Max Planck Society under Dr. Silke Hauf (defended February 2015 with highest honors), and conducted postdoctoral research at Stanford University with Prof. James E. Ferrell. Her PhD work was supported by a Boehringer Ingelheim Fonds fellowship, and her postdoc was funded by a German Research Foundation (DFG) Postdoctoral Fellowship. Her research expertise spans cell cycle regulation and dynamics, post-translational modifications, Xenopus laevis model systems, and live cell microscopy. Dr. Kamenz investigates how kinases and phosphatases intricately regulate cell proliferation and division, with particular interest in the molecular mechanisms that ensure faithful chromosome segregation during mitosis. Her recent work has revealed novel insights into mitotic checkpoint signaling, particularly in early embryonic development where these checkpoints appear to function differently than in somatic cells. Dr. Kamenz's publication record demonstrates a strong focus on the dynamics of cell cycle transitions, with recent papers appearing in high-impact journals including Nature, The Journal of Biological Chemistry, and The Journal of Cell Biology. Her research integrates experimental biochemistry, live-cell imaging, and computational modeling approaches to understand complex regulatory networks. ERC Starting Grant (November 2022) NWO Vidi Grant (July 2021) Mansour Postdoctoral Travel Award (2019) Dr. Kamenz has secured significant research funding including an ERC Starting Grant (€1.5 million) and an NWO XS grant (€50,000) for her project "What limits mitotic checkpoint signaling in the early embryo?" Her research contributes to understanding fundamental biological processes with implications for developmental biology and cancer research. She collaborates extensively within the University of Groningen and with international partners, particularly in the areas of cell cycle research and biophysical approaches to biological problems. Dr. Kamenz leads a research group focused on cell cycle regulation within the Molecular Systems Biology division of the Groningen Biomolecular Sciences and Biotechnology Institute. Her lab combines biochemical approaches using Xenopus egg extracts with live-cell imaging and computational modeling to dissect the molecular mechanisms controlling cell division.

Ana Maria VelezView profile

Associate Professor

• Insect Toxicology
• Environmental Toxicology
• Resistance Management
• +7 more

Ana Maria Velez is an Associate Professor at the Department of Entomology, University of Nebraska-Lincoln. Her research focuses on insect responses to chemical stressors, particularly RNA interference (RNAi) and Bt toxins for pest management. With a 80% research and 20% teaching appointment, she leads the Insect Toxicology Lab and teaches courses like 'Toxins in the Environment' and 'Insecticide Toxicology.' Education: Ph.D. in Entomology, University of Nebraska-Lincoln, 2013 M.S. in Entomology, Universidad Nacional de Colombia, 2009 B.S. in Biology, Pontificia Universidad Javeriana, Colombia, 2006 Her research spans molecular, organismal, and population levels to evaluate transgenic crops and RNAi technologies. Key areas include resistance mechanisms, non-target effects, and risk assessment frameworks. She has extensive publications on western corn rootworm and fall armyworm, emphasizing sustainable pest control. Her work also addresses sublethal impacts on non-target species like monarch butterflies and honeybees. Recent articles highlight RNAi delivery optimization, Bt resistance dynamics, and ecological impacts of insecticides. Her lab collaborates on patents for RNAi-based pest suppression methods targeting chromatin remodeling and developmental genes. Scientific Awards Distinguished Multicultural Alumni (2019) DuPont Young Professor Award (2016) International Congress of Entomology Travel Awards (2016) Widaman Trust Distinguished Graduate Assistant (2011) Milton E. Mohr Teaching Fellowship (2012) The Vélez Arango Lab investigates durability and safety of insect control technologies, with emphasis on RNAi and Bt crops. Their work informs integrated pest management (IPM) systems and regulatory frameworks.

Michael LevineView profile

Professor

• Genomics
• Molecular Biology
• Developmental Biology
• +7 more

Michael Levine is the Anthony B. Evnin '62 Professor in Genomics and Professor of Molecular Biology at Princeton University, where he also serves as Director of the Lewis-Sigler Institute for Integrative Genomics. He joined Princeton in 2015 after a distinguished career at UC Berkeley, where he was Professor of Genetics and held leadership roles in genetics and genomics programs. His research focuses on how noncoding regions of the genome regulate gene expression in space and time during development. His lab has pioneered studies in Drosophila and the protovertebrate Ciona intestinalis , uncovering fundamental mechanisms such as enhancer function, transcriptional bursting, short-range repression, and long-range enhancer-promoter interactions. His work has also revealed evolutionary insights into the origins of vertebrate innovations like the neural crest and neurogenic placodes. Levine's recent publications demonstrate a strong emphasis on quantitative and live-imaging approaches to dissect gene regulation dynamics. His work integrates experimental embryology with computational modeling, especially using deep learning to predict transcriptional outcomes. Themes across his recent articles include biomolecular condensates, chromatin architecture, and the physical principles underlying enhancer function. Elected to the National Academy of Sciences (1998) Molecular Biology Award, National Academy of Sciences (1996) Wilbur Cross Medal, Yale University (2009) EG Conklin Medal, Society of Development Biology (2015) Dr. Levine has trained numerous researchers and co-authored studies with emerging scientists, indicating active mentoring and grant-funded research. His leadership roles at major institutes and sustained publication record reflect a robust, well-supported research program. He has also contributed to national genomics initiatives, including service at the DOE Joint Genome Institute. His lab operates at the intersection of molecular biology, genomics, and quantitative developmental biology, utilizing model organisms and cutting-edge imaging and computational tools to unravel the logic of gene regulatory networks.

Yukiko GotohView profile

Professor

• Neural Development
• Neural Stem/Progenitor Cells
• Epigenetics
• +7 more

Yukiko Gotoh is a Professor at the Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo. She serves as the Deputy Director and Principal Investigator at the International Research Center for Neurointelligence (IRCN). Her research focuses on understanding the mechanisms that regulate neural stem/progenitor cell fate during embryonic brain development and in the adult brain. Dr. Gotoh's research interests include: Genetic and epigenetic regulation of neural stem/progenitor cell fate Neuronal maturation processes Genesis and maintenance of adult neural stem cells Relevance of neural stem/progenitor cell dysregulation in neurodevelopmental disorders such as autism spectrum disorders Investigation of mechanisms regulating neural stem-progenitor cell fate during neocortical development Genetic and epigenetic regulation of neuronal activation Analysis of Dr. Gotoh's recent publications reveals a strong focus on neural stem cell biology, epigenetic regulation, and neurodevelopmental disorders. Her work demonstrates how chromatin modifiers like Polycomb group proteins and HMGA proteins regulate neural stem cell fate decisions during brain development. A significant portion of her research explores the embryonic origins of adult neural stem cells and how dysregulation of these processes contributes to conditions like autism spectrum disorders and schizophrenia. Her laboratory also investigates the basic mechanisms of cellular responses to viral infection in the brain and their relevance to neurodevelopmental disorders. Dr. Gotoh has made significant contributions to understanding: The role of Polycomb group proteins in neural development How chromatin modifiers regulate neurogenic potential Cell cycle regulation in neural stem cells The PDK1-Akt pathway in neuronal migration Layer-specific heterogeneity of astrocytes Mechanisms underlying schizophrenia-related abnormalities Dr. Gotoh's laboratory conducts research on multiple fronts related to neural development and stem cell biology. Her team investigates: Mechanisms regulating neural stem-progenitor cell fate during neocortical development Genetic and epigenetic regulation of neuronal activation The embryonic origin of adult neural stem cells Dysregulation of neural stem-progenitor cell and neuronal fate in neurodevelopmental disorders Innate immune responses in the brain

Petra SchwilleView profile

Professor

• Molecular Biophysics
• Cellular Biophysics
• Synthetic Biology
• +5 more

Prof. Dr. Petra Schwille is a Director at the Max Planck Institute of Biochemistry and former C4 Professor of Biophysics at Dresden University of Technology . Her work spans molecular and cellular biophysics, synthetic biology, and single-molecule techniques. Academic disciplines: Natural sciences, biological sciences, physical sciences Key roles: Editorial Board member (Nature Methods, Biophysical Journal), Governing Council of Biophysical Society Research Focus includes membrane biophysics, protein interactions, and microfluidic systems. Her publications emphasize Fluorescence Correlation Spectroscopy (FCS) , receptor-ligand dynamics, and self-organization in bacterial cell division. Developed in vitro models for spatial regulation in cells Explored calmodulin availability and morphogen gradient formation Scientific Recognition includes prestigious awards like the Gottfried Wilhelm Leibniz Prize (2010) and the Biofuture grant (1998) . Max Planck Fellow (2005) Young Investigator Award (2003) Leadership & Service involves roles such as Dean of Studies for Nanobiophysics at TU Dresden and Vice Dean of the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB) . She also contributes to editorial and advisory boards in biophysics and science policy.

Miler T. LeeView profile

Associate Professor

• Gene Regulation
• Developmental Biology
• Computational Genomics
• +9 more

Miler T. Lee is an Associate Professor at the University of Pittsburgh , focusing on gene regulation during early embryonic development through high-throughput experimental and computational genomics. He earned his Ph.D. in Genomics and Computational Biology in 2009 from the University of Pennsylvania under Dr. Junhyong Kim, followed by postdoctoral work with Dr. Antonio Giraldez at Yale University. Joining the university in 2016, his research spans maternal-to-zygotic transition (MZT), RNA stability, pluripotency networks, and evolutionary developmental biology, utilizing model organisms like zebrafish, Xenopus, and Hydractinia symbiolongicarpus. Key Research Themes: Maternally inherited RNA dynamics during embryogenesis Mechanisms of RNA degradation and transcriptome remodeling Evolution of pluripotency networks in hybrid species Role of zinc signaling in fertilization barriers Computational tools for RNA regulation and sensing Scientific Awards: Pan-American Society for Evolutionary Developmental Biology Junior Faculty Award (2024) Outstanding New Investigator – International Xenopus Board (2023) Basil O'Connor Scholar – March of Dimes (2017-2019) Recent publications highlight his work on enhancer classification, RNA degradation mechanisms, and cross-species MZT comparisons. His lab develops innovative methods like RESA for regulatory sequence analysis and studies evolutionary divergence in RNA localization patterns. While the articles span computational and experimental approaches, they consistently address RNA's role in cellular identity, developmental timing, and evolutionary adaptation. Applications include understanding pluripotency, designing RNA biosensors, and elucidating fertilization barriers. Prospective Ph.D. students are encouraged to contact him for opportunities in gene regulation, development, evo-devo, and computational genomics.

Oscar Meruvia-PastorView profile

Professor

• Interactive 3D Graphics
• Non-Photorealistic Rendering
• Augmented Reality
• +8 more

Dr. Oscar Meruvia-Pastor is a faculty member in the Department of Computer Science at Memorial University of Newfoundland, within the Faculty of Science. He holds a B.Sc. from ITESM-Monterrey, Mexico, an M.Sc. from the University of Alberta, and a Ph.D. from Otto-von-Guericke Universität Magdeburg, Germany. His research focuses on interactive 3D graphics, non-photorealistic rendering, and biomedical visualization, with applications in telepresence systems, augmented reality (AR), and virtual reality (VR). He has developed tools like OMARC for respiratory condition training and GeNET for gene co-expression network analysis. Dr. Meruvia-Pastor has supervised numerous graduate students and contributed to over 50 publications. His work includes evaluating stereo correspondence methods in AR, robot arm manipulation via depth sensors, and smartphone integration in immersive VR. He has been recognized with awards such as the Best HCI Poster at Graphics Interface 2014 and a semi-finalist poster at SIGGRAPH 2015. He teaches courses in computer science, including computer graphics, multimedia development, and introductory science modules. His research lab focuses on 3D telepresence, medical visualization, and human-centered VR/AR solutions. His academic contributions span software tools for medical imaging analysis, interactive visualization systems, and educational technologies. He actively collaborates with health professionals to advance telemedicine and remote procedural training through AR platforms. His work bridges computer graphics with real-world applications in healthcare, education, and environmental advocacy.

Maja MatisView profile

Researcher

• Cell Biology
• Developmental Biology
• Biophysics
• +3 more

Dr. Maja Matis is a Group Leader at the University of Muenster's Center for Molecular Biology of Inflammation (ZMBE) within the Institute of Cell Biology. Her research focuses on understanding the mechanical role of microtubules in tissue morphogenesis, particularly how microtubule-generated forces contribute to tissue remodeling through coordinated cellular behaviors. She leads the Matis Lab, which employs advanced microscopy techniques and genetic approaches to study cytoskeletal mechanics in developmental contexts. Key research areas include the structural regulation of microtubules, mechanics-driven cell shape changes, and integration of forces at adherens junctions. Her interdisciplinary projects combine biophysics, developmental biology, and quantitative imaging to unravel mechanisms underlying collective cell behavior during tissue formation. Notable contributions include studies on microtubule compression dynamics in epithelial tissues and the role of PCP signaling in patterning microtubule networks. She collaborates with institutions like the Cells in Motion Cluster of Excellence and has mentored multiple PhD/MD students. Her work is published in high-impact journals such as Nat. Commun. and Nat. Cell Biol.

Benjamin SimonsView profile

Professor

• Stem Cell Biology
• Developmental Biology
• Cancer Biology
• +3 more

Benjamin Simons is the Royal Society EP Abraham Professor and Herchel Smith Professor of Physics at the University of Cambridge. He serves as Director of the Gurdon Institute, Senior Group Leader at the Gurdon Institute, Principal Investigator at the Cambridge Stem Cell Institute, and member of the Theory of Condensed Matter physics group. He is also a Fellow of St. John's College, Cambridge. His research integrates quantitative approaches from physics and mathematics with experimental biology to investigate stem cell fate regulation in tissue development, maintenance, and cancer pathogenesis. Research focuses on: Stochastic cell fate decisions in epithelial tissues Self-organization principles in tissue morphogenesis Single-cell lineage tracing and gene expression analysis Mathematical modeling of stem cell dynamics Cancer initiation through stem cell reprogramming Publication analysis reveals consistent themes: spatial dynamics of stem cell niches, mechanical regulation of cell fate, computational modeling of tissue organization, and evolutionary principles in cancer development. Recent work emphasizes in vivo lineage tracing, single-cell omics, and interdisciplinary approaches bridging physics and biology. Scientific Awards: Fellow of the Royal Society (FRS) Fellow of the Academy of Medical Sciences (FMedSci) Leads an interdisciplinary research group combining wet-lab experiments (lineage tracing, single-cell genomics) with theoretical modeling. Research supported by EPSRC, MRC, Wellcome Trust, Cancer Research UK, and Royal Society grants. Current projects include gliomagenesis mechanisms, spermatogenic wave regulation, and injury response pathways co-opted in cancer.

Raymond KellerView profile

Professor

• Morphogenesis
• Cell Biology
• Developmental Biology
• +3 more

Raymond Keller is the Thomas Jefferson Professor of Biology at the University of Virginia. He leads the Keller Laboratory, which investigates cellular and molecular mechanisms driving early amphibian morphogenesis, focusing on convergent extension movements during gastrulation and neural tube formation. His work integrates high-resolution imaging of cell motility with biomechanical analyses of embryonic tissues to understand how molecular events generate forces shaping the embryo. Research interests include embryonic tissue mechanics, cell intercalation dynamics, and the biomechanical basis of vertebrate body plan formation. Collaborations include work with Ann Sutherland (UVA School of Medicine) on mouse early morphogenesis, combining amphibian and mammalian systems for comparative insights. Notable contributions include pioneering studies on convergent extension, direct embryonic force measurements, and innovative tissue engineering approaches. His research bridges developmental biology with biophysics and engineering principles.

• Organoid Engineering
• Systems Biology
• Developmental Biology
• +3 more

Keisuke Ishihara is an Assistant Professor in the Department of Computational and Systems Biology at the University of Pittsburgh School of Medicine. His research focuses on engineering human brain and cardiac organoids using genetic, chemical, and computational approaches to uncover novel regulatory mechanisms and physical principles underlying tissue development. His lab is located at Biomedical Science Tower 3, with an office in room 10020A. Dr. Ishihara holds a PhD in Systems Biology from Harvard University. His work bridges synthetic biology, developmental biology, and biophysics to address fundamental questions in organogenesis and cellular morphogenesis. Recent research highlights include studies on BMP-mediated neural tube patterning in organoids and the biophysical dynamics of microtubule assemblies in large cells. Publications from his lab emphasize interdisciplinary approaches to understand cell size scaling, mitotic spindle dynamics, and self-organization in synthetic tissues. His team has contributed to advancements in organoid technology, uncovering dormant genetic programs and physical principles governing tissue architecture. Laboratory activities are centered at the University of Pittsburgh, collaborating with the School of Medicine's computational and systems biology initiatives. For more details, visit his lab website linked below.