Pauliina DamdimopoulouView profile
Professor
Professor Pauliina Damdimopoulou is a leading researcher in reproductive biology at Karolinska Institutet's Department of Women's and Children's Health. She leads the "Chemicals and female fertility" research group, investigating how environmental chemicals impact female fertility and ovarian function. With over 15 years of experience in endocrinology, reproductive biology and toxicology, she has established herself as an expert in reproductive toxicology and currently serves as ERC ambassador and Professor since 2025. Her educational background includes: Docent (Associate Professor) in endocrine physiology (2015, University of Turku, Finland) Docent in toxicology (2021, Karolinska Institutet) Professor Damdimopoulou's research focuses on environmental exposures like industrial chemicals and air pollution and their links to reduced fertility in women. She's particularly interested in how these exposures affect ovaries and oocytes, which form before birth and represent a finite, non-renewable resource. Her work combines epidemiological studies with controlled in vitro exposure studies to unravel molecular mechanisms by which chemicals affect ovarian function, with the ultimate goal of developing better tools for reproductive toxicity testing. Her recent publications (2023-2025) show a strong interdisciplinary focus on how specific chemical classes (phthalates, PFAS, persistent organic pollutants) affect ovarian function, follicular development, and female fertility. There's a clear trend toward developing better in vitro models for reproductive toxicity testing, mapping molecular pathways affected by environmental chemicals, and translating these findings into improved regulatory frameworks. Her work bridges epidemiology, molecular biology, toxicology, and clinical reproductive medicine. Her scientific awards include: ERC Consolidator Grant (2023) - EUR 2 million for the SAFER project (SAfeguarding female FERtility-development of human-relevant in vitro tools for reproductive toxicity) Professor Damdimopoulou has extensive experience in academic mentoring, having supervised numerous undergraduate students through laboratory training, MSc thesis projects, and served as main supervisor for multiple PhD students. She has formal training in higher education pedagogy and doctoral student supervision. Her research is supported by significant grants including the ERC Consolidator Grant for the SAFER project, which aims to develop human-relevant in vitro tools for reproductive toxicity testing to replace current animal-based methods. She leads the "Chemicals and female fertility" research group at Karolinska Institutet and co-leads the Environmental Endocrinology Focus Area of the European Society of Endocrinology. Her lab develops advanced tissue culture models including 3D spheroid systems and works with human ovarian tissue samples to study chemical effects on reproductive function. The group maintains active collaborations with researchers across Europe and participates in major research initiatives focused on endocrine disruption and reproductive health.


