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Terence OzolinsView profile

Associate Professor

• Developmental Toxicology
• Cardiac Birth Defects
• Ventricular Septation
• +2 more

Terence Ozolins is an Associate Professor in the Department of Biomedical and Molecular Sciences at Queen's University's Faculty of Health Sciences. He holds cross-appointments with the Translational Institute of Medicine (TIME) and teaches courses in pharmacology and toxicology, including PHAR 480: Drug Discovery and Development. His research focuses on the etiology of ventricular septation defects (VSD) using rat models to understand how environmental influences during gestation cause structural heart defects and long-term postnatal cardiac dysfunction even after spontaneous repair. The lab investigates molecular mechanisms underlying teratogen-induced cardiac malformations and persistent physiological abnormalities. Publications demonstrate expertise in high-resolution fetal ultrasound imaging, molecular pathways of teratogenesis, and transgenerational effects of chemical exposures. Recent work explores AP-1 transcription factor regulation in embryotoxicity. Scientific Awards: Safety Sciences Award for Scientific Excellence (2003) Dr. Ozolins maintains collaborations with clinical researchers and previously spent 11 years in pharmaceutical industry research. Current projects examine epigenetic mechanisms in congenital heart defects and developmental origins of adult cardiovascular disease.

• Physiology
• Neuroscience
• Synaptic Plasticity
• +3 more

Karen Ting Chang, PhD , is an Associate Professor of Physiology and Neuroscience at the University of Southern California's Keck School of Medicine. Her research focuses on synaptic plasticity, mitochondrial dynamics, and molecular mechanisms in neurodegenerative diseases and developmental disorders. Using Drosophila models, she investigates how pathways like secretory autophagy, DSCR1 regulation, and integrin signaling affect neural function. Research Trends : Her publications highlight synaptic remodeling, calcium signaling, and cross-disease connections between Down syndrome and Alzheimer's pathology. Key methodologies include genetic models, endocytosis studies, and mitochondrial transport analysis. Contact : Email: changkt@usc.edu

Shwetal MehtaView profile

Adjunct Professor

• Cancer Biology
• Neuro-Oncology
• Molecular Biology
• +3 more

Dr. Shwetal Mehta is an Adjunct Professor at Arizona State University (ASU), holding affiliations in the School of Life Sciences and School of Molecular Sciences. She is also part of the Ivy Brain Tumor Center. Her research focuses on molecular mechanisms driving glioma biology, particularly cancer stem cells and their roles in therapy resistance. She earned a Master’s in Molecular Biology from the Tata Institute of Fundamental Research, India, and holds a PhD (details not fully disclosed in text). Dr. Mehta teaches courses such as BIO 495 (Undergraduate Research) and NEU 591 (Seminar) across multiple semesters. Her lab investigates neurodevelopmental pathways hijacked by cancer stem cells, including epigenetic regulation (e.g., HDAC1), 3D tumor models, and glioma-vascular interactions. As Deputy Director and Pre-Clinical Core Leader at the Ivy Brain Tumor Center, she oversees preclinical trials for glioblastoma therapies. Her research has led to discoveries in Wnt signaling, glial signatures, and drug-response mechanisms in gliomas. Despite no awards explicitly listed, her work bridges basic science and clinical translation. Lab members include postdoctoral fellows (e.g., Sonam Patel, Gozde Uzunalli) and research technicians. Current projects explore genetic/epigenetic deregulations in cancer stem cells and vulnerabilities for novel therapies.

Jeffrey PetersView profile

Professor

• Molecular Toxicology
• Carcinogenesis
• Gene Regulation
• +3 more

Dr. Jeffrey Peters is a Distinguished Professor of Molecular Toxicology and Carcinogenesis and Deputy Director of the Penn State Cancer Institute. He holds affiliations with the Department of Biochemistry and Molecular Biology, the Molecular, Cellular, and Integrative Biosciences Program, and the Veterinary and Biomedical Sciences department. His research focuses on peroxisome proliferator-activated receptors (PPARs) in toxicology, carcinogenesis, and metabolic regulation. Education: PhD from UC Davis, postdoctoral fellowships at the National Cancer Institute (NCI) and UC Davis Institute of Toxicology. Editor-in-Chief of Toxicological Sciences and former Chair of the NIH’s Cancer Drug Development and Therapeutics panel. Research interests include PPAR signaling in epithelial cancers, dietary lipid modulation, and epigenetic interactions. Notable contributions include elucidating PPARβ/δ’s role in colon and breast cancer suppression via ERK/AKT pathway regulation. His lab uses mouse models, metabolomics, and genomic approaches to study cancer chemoprevention and metabolic diseases. Recent work highlights species differences in PPARα-mediated toxicity and the role of PPARβ/δ in modulating liver and skin carcinogenesis. Awards include the George H. Scott Memorial Award and the Huck Award for Life Sciences Research. Key Contributions: PPARβ/δ’s tumor-suppressive mechanisms, PPAR-ligand development for chemoprevention Grants: NIH-funded studies on PPAR signaling and cancer Labs/Teams: Peters Research Group at Penn State, focusing on PPAR biology and toxicology

• Neurophysiology
• Neuroscience
• Medical Education
• +3 more

Martin Garwicz is a Professor of Neurophysiology and Course Director at Lund University, serving as Centre Director of the Neuronano Research Center (NRC) and the Birgit Rausing Centre for Medical Humanities (BRCMH). His research focuses on cerebellar information processing, human evolution, and medical education. He has contributed to understanding developmental milestones like walking onset in mammals and the impact of carnivory on human evolution. His work intersects neuroscience, evolutionary biology, and healthcare education, emphasizing evidence-based practices. Key affiliations include the NRC and BRCMH, where he leads interdisciplinary projects on topics like existential resilience and healthscapes. Garwicz has organized major events like Neuroscience Day 2025 and contributed to initiatives promoting STEM education. His research spans over 65 publications, with recent work addressing medical student training in evidence-based medicine and cerebellar microcircuit dynamics. He coordinates projects such as 'Evolutionary Roots of Human Development' (2008–present) and 'ERiCi: Existential Resilience,' blending scientific and humanities perspectives. Garwicz’s activities include invited lectures on medical humanities and public talks on topics like digital immortality.

• Neurobiology
• Ophthalmology
• Neuroscience
• +3 more

In-Jung Kim is an Associate Professor in Ophthalmology and Neuroscience at Yale School of Medicine. Her research focuses on retinal development, visual circuitry, and neural mechanisms underlying fear-related behaviors. She employs mouse genetics, optogenetics, and advanced imaging techniques. Key affiliations include the Interdepartmental Neuroscience Program and the Wu Tsai Institute. Her work has been supported by grants from the NIH, Whitehall Foundation, and E. Matilda Ziegler Foundation. Education: PhD from State University of New York at Buffalo (2003), Postdoctoral training at Harvard University and Washington University in St. Louis. Research Interests: Retinal ganglion cell development, optic nerve regeneration, and fear circuitry in the midbrain. Her lab explores how specific retinal neurons regulate defensive responses to visual threats, with recent breakthroughs in identifying molecular regulators of neural repair. Notable Awards: NIH Pathway to Independence Award (2010), Whitehall Foundation Grant (2014), and E. Matilda Ziegler Foundation Grant (2015). Lab Location: 300 George Street, Ste 8300, New Haven, CT. Active collaborations include work with Jonathan Demb, Pouyan Rahmani, and Stephen Strittmatter.

• Leukemia
• PML
• SUMO
• +4 more

Hugues de Thé is a French physician-scientist holding the Professor position at Collège de France since 2014. He has been an Attending Physician at St. Louis Hospital in Paris since 1995 and led a CNRS/University of Paris VII Research Unit at the same hospital until 2019. His academic career spans prestigious roles at University of Paris (1991-2014) and leadership positions in scientific advisory boards, including the Bettencourt Schuller Foundation. MD (1989) and PhD (1990) from Parisian universities Expertise in leukemia, PML, SUMO, and targeted therapies His research fundamentally advanced understanding of acute promyelocytic leukemia (APL) pathogenesis and treatment. By elucidating mechanisms of retinoic acid receptor alpha (RARα) fusion proteins and PML nuclear bodies , he pioneered combination therapies using retinoic acid and arsenic , revolutionizing APL treatment. His work on protein degradation pathways informs modern targeted cancer therapies. Scientific Awards : Advanced Grant, European Research Council (2024) Sjöberg Prize, Swedish Royal Academy of Sciences (2018) French Legion of Honour (2010) Member, French Academy of Science (2011) He advises institutions like INSERM and ARC, and his grants include multiple ERC grants and international collaborations. His laboratory studies integrate mouse models , proteomics , and molecular oncology to uncover cancer mechanisms.

Laurie A. BoyerView profile

Professor

• Developmental Biology
• Cardiovascular Biology
• Chromatin Remodeling
• +4 more

Laurie A. Boyer is a Professor of Biology and Biological Engineering at the Massachusetts Institute of Technology (MIT), affiliated with the Koch Biology Building. She serves as Co-Undergraduate Officer and leads research on gene regulatory mechanisms in heart development and regeneration using embryonic stem cells and mouse models. Her work integrates genomic, genetic, biochemical, and cell biological approaches to understand chromatin dynamics and lineage commitment, with applications in cardiac tissue engineering and regeneration. Education: PhD, 2001, University of Massachusetts Medical School BS, 1990, Biomedical Science, Framingham State University Research Interests: Dr. Boyer’s research focuses on the interplay between chromatin remodeling, epigenetic regulation, and transcriptional networks that drive heart development. She investigates how ATP-dependent chromatin remodelers influence lineage specification and explores methods to stimulate cardiac regeneration. Her lab combines advanced genomic techniques with tissue engineering to model 3D cardiac architecture, aiming to uncover regulatory circuits underlying normal and diseased heart development. Publications: Her recent work includes breakthroughs in high-throughput expansion microscopy for scalable super-resolution imaging, metabolic modulation of mesenchymal stem cells for cartilage repair, and the role of long noncoding RNAs like Braveheart in cardiovascular lineage commitment. These studies span molecular mechanisms of chromatin dynamics to translational applications in regenerative medicine. Awards & Honors: Pew Scholars Award in the Biomedical Sciences (2008) Smith Family Award for Excellence in Biomedical Science (2009) Scientific American World’s 50 Top Leaders in Research (2006) Irvin and Helen Sizer Career Development Award (2012) Grants & Collaborations: Dr. Boyer oversees grants from organizations like the NIH and American Heart Association. She collaborates with teams on interdisciplinary projects, including tissue engineering and stem cell therapies. Her lab also develops innovative microscopy techniques to advance cellular imaging scalability. Labs & Teams: Her laboratory at MIT’s Koch Institute integrates computational biology, bioengineering, and molecular biology. The lab focuses on translating fundamental discoveries into clinical applications for heart disease and regeneration.

Maria Valadez IngersollView profile

Researcher

• Coral Biology
• Molecular Ecology
• Immunology
• +7 more

Maria Valadez Ingersoll is a postdoctoral researcher at Woods Hole Oceanographic Institution, specializing in molecular ecology and marine organism immunology. She holds a B.A. from Swarthmore College and a Ph.D. in Cellular and Molecular Biology from Boston University, where she studied cnidarian-algal symbiosis under Drs. Sarah Davies and Tom Gilmore. Education: B.A. (Swarthmore College), Ph.D. (Boston University) Current Role: Postdoctoral Scholar at Woods Hole Oceanographic Institution Her research explores molecular responses to climate change in corals and sea anemones, symbiosis-immunity tradeoffs, and marine microbiology. She has extensive experience in molecular biology, bioinformatics, and scientific diving. Maria's publications focus on cnidarian-algal symbiosis, SARS-CoV-2 protein dynamics, nitrogen isotope proxies, and stress responses in marine organisms. Her work intersects with understanding coral resilience and copepod diapause mechanisms. Contact: maria.v.ingersoll@gmail.com

Bruce CarlsonView profile

Professor

• Animal Communication
• Neurobiology
• Sensory Information Processing
• +3 more

Bruce Carlson is a Professor of Biology at Washington University, specializing in neuroethology and evolutionary neuroscience. His laboratory focuses on the neurobiological basis of sensory information processing, animal communication, and the evolution of brain and behavior. Using weakly electric fish as a model system, his research explores how nervous systems integrate sensory input to guide behavior and how evolutionary pressures shape sensory systems and brain structures. Recent work includes a $980,000 NSF grant investigating neuroplasticity's role in behavioral evolution. The Carlson Lab employs electrophysiology, neuroanatomy, computational modeling, and behavioral analysis to study electrosensory systems. They emphasize the interplay between ecological context and evolutionary forces, particularly in mormyrid fish. Outreach initiatives include partnerships with Harris-Stowe State University to engage underrepresented students in research. Key research themes include the evolutionary drivers of sensory circuit changes, the link between brain size and energetic costs (e.g., reduced hypoxia tolerance in encephalized species), and the role of early-life experiences in shaping long-term behavioral outcomes. Publications span topics like synaptic plasticity, neural coding of communication signals, and comparative brain evolution in teleost fishes. Scientific awards include significant NSF funding, and his work has been highlighted in outlets like Science , Proceedings of the Royal Society B , and Neuroscience News . The lab also contributes to public education, using electric fish to illustrate neuroplasticity and growth mindset principles for K-12 students.

• Developmental Biology
• Genetics
• Pediatrics
• +3 more

Mustafa Khokha, MD, is an Adjunct Professor in the Department of Pediatrics at Yale School of Medicine. His research focuses on understanding the molecular mechanisms underlying congenital malformations and critical illnesses in infants using genetic sequencing and Xenopus tropicalis as a model system. He directs the Pediatric Genomics Discovery Program (PGDP), which identifies genetic causes of undiagnosed diseases in children. Khokha’s work bridges clinical care and research, aiming to translate genetic discoveries into improved patient outcomes. Education: MD from Northwestern University Medical School (1995), BS from Northwestern University (1991), Residency in Pediatrics at St. Louis Children's Hospital (1995–98), Fellowship in Pediatric Critical Care at University of California, San Francisco (2002), and Fellowship in Molecular & Cell Biology at University of California, Berkeley (2006). His research integrates developmental biology and genetics to study embryonic patterning defects, particularly in congenital heart disease and facial malformations. Using high-throughput screens in Xenopus, he identifies genes responsible for birth defects and elucidates their functional roles. Key achievements include discovering the role of GALNT11 in laterality and cilia function, and linking CACNA1G to left-right patterning. His work on β-catenin nuclear transport and Wnt signaling has advanced understanding of developmental pathways. Awards: Mallinckrodt Scholar (2014), Mae Gailani Junior Faculty Teaching Award (2010), Harvey Colten Award (2009). Labs/Teams: Khokha Lab, part of the Program in Translational Biomedicine and the Yale Center for Genomic Health. Collaborations include the Pediatric Critical Care Transport Program and the Yale Medicine team.

• Breast Cancer
• Melanoma
• DNA Damage Response
• +3 more

David F. Stern is a Professor of Pathology at Yale University School of Medicine, serving as Vice Chair for Basic and Translational Sciences and Associate Director of Shared Resources at Yale Cancer Center. He earned his BS from MIT (1976), PhD from UC San Diego/Salk Institute (1983), and completed postdoctoral training at MIT's Whitehead Institute. His research focuses on growth factor signaling in breast cancer and melanoma, particularly ERBB receptor pathways and drug resistance mechanisms. He also investigates DNA damage responses and has contributed to understanding ErbB2/HER2's role in cancer. Education: BS in Biology, MIT (1976) PhD in Biology, UC San Diego/Salk Institute (1983) Postdoctoral Fellowship, Whitehead Institute/MIT (1988) Research Interests: Stern's work spans breast cancer, melanoma, and DNA damage pathways. He explores how ERBB receptors drive malignancy and develops strategies to counteract therapeutic resistance. Recent efforts include combinatorial drug screening for triple-negative breast cancer and analyzing ERBB4's role in cholesterol metabolism. Awards: Recognized for contributions to cancer research, including honors from Yale Cancer Center (2022–2023). Labs/Teams: Leads the Stern Lab, collaborating with researchers like David Rimm and Zhaoxia Sun on signaling pathways and targeted therapies. Active in Yale's Cancer Center scientific leadership and training initiatives.

• Psychiatry
• Clinical Psychology
• Neuroscience
• +5 more

Dr. Rand J. Gruen is an Assistant Clinical Professor in the Department of Psychiatry at Yale School of Medicine. He specializes in psychotherapy and supervises residents in clinical practice. His academic background includes a PhD in Psychology from the University of California, Berkeley (1985), followed by postdoctoral training at Yale School of Medicine (1989). Education: BA, MA, and PhD in Psychology, University of California, Berkeley (1982-1985) Postdoctoral Fellow, Yale University School of Medicine (1989) Research Focus: Dr. Gruen's work spans clinical and neuroscience domains. Key areas include: - Neuropharmacology of GABAergic and dopaminergic systems - Stress neurobiology and its impact on brain function - Alzheimer's disease mechanisms (amyloid-beta pathology) - Psychological aspects of stress appraisal and coping - Psychotherapeutic approaches to depressive disorders Publications Trend: His research demonstrates cross-disciplinary expertise: - Early work (1980s-1990s) focused on neurochemical mechanisms (GABAA receptors, dopamine pathways) - Later studies (2000s) addressed Alzheimer's biomarkers and clinical psychology - Consistent exploration of brain-behavior relationships across development and stress contexts Grants & Advising: No specific grants or advisee names are listed in available records. His clinical supervision role suggests involvement in resident training programs. Labs/Teams: Affiliated with Yale Psychiatry Department research programs, though specific lab affiliations are not detailed in the provided information.

Diana Tavares FerreiraView profile

Assistant Professor

• Cellular and molecular mechanisms of axonal integrity
• RNA transport and regulation
• Computational neuroscience
• +3 more

Diana Tavares Ferreira is an Assistant Professor of Neuroscience at the University of Texas at Dallas (UTD) within the School of Behavioral and Brain Sciences . Her research focuses on understanding cellular and molecular mechanisms underlying axonal integrity in sensory neurons, particularly in neuropathies and neurodegenerative diseases. Education & Training: Postdoctoral Researcher in Neuroscience at UTD (2023) PhD in Neuroscience from the University of Sheffield, UK (2018) PharmD/MS in Pharmaceutical Sciences from the University of Coimbra, Portugal (2013) Research Interests: RNA transport dynamics in distal axons Role of non-coding RNAs (e.g., miRNAs) in sensory neuron function Computational integration of multi-omics data (single-cell, spatial transcriptomics) Mechanisms of axon-soma communication and axonal regeneration Her lab, the Axon Biology and Neuroinformatics Lab , combines experimental and computational approaches to decode how RNA regulation impacts nerve health and disease. Awards & Recognition: Peter J. Dyck Abstract Prize (2022) for diabetic neuropathy research Catalyst Studentship (2016) from the Higher Education Funding Council for England Grants & Funding: Data Core UTD PRECISION Pain Center (National Institute of Neurological Disorders and Stroke, 2022–2027) Dr. Ferreira is currently accepting graduate students and collaborates on projects involving spatial transcriptomics and translational control in chronic pain mechanisms.

Larry FeigView profile

Professor

• Molecular Biology
• Epigenetics
• Stress Physiology
• +3 more

Larry Feig is a Professor in the Department of Developmental, Molecular and Chemical Biology at Tufts University School of Medicine. His research focuses on molecular mechanisms underlying sex-dependent effects of stress across generations, particularly involving Ras-GRF1 and epigenetic inheritance via sperm miRNAs. He holds a PhD from Harvard University and has held faculty positions since 1987. He teaches courses in molecular biology and signal transduction, and has been awarded the Distinguished Faculty Award (2017). Education: PhD in Biological Sciences, Harvard University (1982) MS in Chemistry, Massachusetts Institute of Technology (1976) BS in Chemistry, Columbia University (1974) Research Interests: Feig's lab investigates: Sex-specific stress responses in adolescents Transgenerational epigenetic inheritance via sperm miRNAs Lamarckian inheritance mechanisms in mammals Neuroendocrine regulation of HPA axis Publications Trends: Recent work emphasizes miRNA-mediated transgenerational effects of paternal stress exposure. Key themes include: Role of miR-34c/449 in stress transmission Epigenetic mechanisms in multi-generational behavior Interactions between astrocytes and sperm biology Neurodevelopmental impacts of environmental enrichment Grants & Funding: Active NIH grants include studies on: Sperm miRNAs in trauma transmission (2020-2024) Paternal stress effects across generations (2015-2020) Professional Activities: NIH Study Section reviewer (2019) Member, Tufts Cancer Center (2006-2015) Program Director, Biochemistry Program (2001-2020) Labs/Teams: His lab collaborates on projects involving: Mouse behavioral models Epigenetic analysis techniques 3D tissue models for cancer research