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Maia Delage Toriel is a dermatologist and researcher at Institut Pasteur , focusing on Hidradenitis Suppurativa (HS) pathogenesis, microbiota interactions, and innovative therapeutic approaches. She leads key projects like SHINE-HS (hormonal influences), ABCESS2 (antibiotic regimens), and ROXANE (genetics and microbiota). Education: Medical studies at University of Necker (1997–2005) Dermatology residency at CHRU Tours (2005–2009) Diploma in Skin Cancerology (2008–2009) Head of Clinic Assistant in Dermatology at Bobigny (2009–2012) Research Interests center on HS etiology, including: Microbiota-host interface dysregulation Tryptophan catabolism and inflammation Sex-related dimorphism in disease manifestation Antibiotic resistance patterns Development of dynamic severity scoring systems (e.g., IHS4) Publications and clinical trials highlight her work on antimicrobial strategies, microbial profiling, and surgical outcomes. Her studies integrate metagenomics , metabolomics , and clinical data to address HS complexity. Collaborations span multidisciplinary teams at Institut Pasteur, focusing on translational immunology, microbiome dynamics, and open science initiatives.

• Dermatology
• Microbiology
• Inflammation
• +5 more

Anne Lafont is a Professor at the École des hautes études en sciences sociales (EHESS), where she is Director of Studies and affiliated with the Center for Research on Arts and Language (CRAL) and the Center for History and Theory of the Arts (CEHTA). Her work focuses on art history, visual cultures of modern worlds, knowledge and creation in colonial societies, and intersections of art, race, and gender studies. Key Research Areas: Art History, Visual Cultures, Colonial Societies, Art and Race, Historiography, Women's History in Art. Lafont has published extensively on art and knowledge in imperial contexts, including The Learned Artist Conquering the Modern World (2010) and Art and Race. The African (all) against the Eye of the Enlightenment (2019, winner of the Arnold and Vitale Blokh Prize). She co-edited Africa and the World. Stories Reconnected from Prehistory to the 21st Century (2022) and contributed to the 2019 Musée d'Orsay exhibition The Black Model from Géricault to Matisse . Her 2012 edited volumes Plumes et Pinceaux. Discours de femmes sur l’art en Europe 1750-1850 highlight gender in art discourse. She taught at Williams College (2021-2022) through a Clark Professorship and received a Villa Albertine grant for research on African-American art. Scientific Awards: Maryse Condé Prize for Research Arnold and Vitale Blokh Prize for L’art et la race (2019) Lafont's recent work addresses transcultural objects, racial social relations, and contested heritage, reflecting her commitment to recentering art history through postcolonial and gendered lenses.

• Art History
• Visual Cultures of Modern Worlds
• Colonial Societies
• +7 more

Michele Boniotto is a researcher at the University of Verona's Department of Molecular and Translational Medicine, focusing on immunology, genetics, and dermatology. His work spans molecular mechanisms in skin diseases and evolutionary aspects of host defense peptides. Research Focus Dr. Boniotto's research examines: Genetic factors in hidradenitis suppurativa Beta-defensin evolution and function Aquaporin-3 role in skin homeostasis Photobiomodulation therapies HLA-DR expression in septic shock His publications show interdisciplinary approaches combining molecular biology, clinical dermatology, and bioinformatics to understand complex disease mechanisms. Scientific Contributions 2025: Keratin filament-melanin interactions 2025: Polygenic risk scoring for HS 2024: Aquaporin-3 dysregulation in HS 2023: NCSTN mutations in familial HS 2022: Holistic HS health records 2020: Photobiomodulation for HS

• Immunology
• Genetics
• Dermatology
• +2 more

Philippe Cinquin is a Professor of Medical Informatics and Director of TIMC-IMAG (UMR5525), a CNRS-Université Joseph Fourier research unit. He leads the CAMI (Computer Assisted Medical Interventions) Labex and co-heads INSERM's CIC-IT 803 clinical investigation center. With a PhD in Applied Mathematics and Medical Doctor qualification, he pioneered surgical robotics and computer-aided interventions since 1984, benefiting over 100,000 patients through startup innovations. His recent work focuses on symbiotic implantable devices, energy scavenging for medical implants, and hydrogen therapy. He received the 2013 CNRS Innovation Award and 2014 Ambroise Paré Surgical Award. Research interests span biomimetic devices, medical robotics, and innovative therapies including transdermal hydrogen delivery. He has developed implantable systems like intestinal reactors and biosensors, with applications in diabetes treatment and pandemic response. His work integrates mathematics, signal processing, and nanotechnology to advance minimally invasive surgery and autonomous medical implants. Key contributions include virtual fluoroscopy systems for navigation, enzymatic biofuel cells, and reusable PPE sterilization methods during the pandemic. His interdisciplinary teams collaborate across engineering, medicine, and computer science to address clinical challenges through technological innovation. Education: PhD in Applied Mathematics; Medical Doctorate Grants & Startups: Founded multiple companies commercializing surgical navigation systems and diagnostic devices Labs: TIMC-IMAG, CAMI Labex, CIC-IT 803 clinical innovation center

• Computer-Assisted Medical Interventions (CAMI)
• Medical Robotics
• Biomimetic Medical Devices
• +4 more

Rachel Golub is a Professor of Immunology at Université Paris Diderot (Paris 7) and heads the Lymphopoiesis Unit at the Institut Pasteur, INSERM U668, in Paris. Her research centres on innate lymphoid cell (ILC) biology, Notch signalling, and their implications in liver cancer, inflammation, and tissue regeneration. Education: PhD in Developmental Biology, Université Paris 6, 1997 HDR (Habilitation), Université Paris 7, 2007 Research Interests: Professor Golub investigates how innate lymphoid cells develop from fetal and adult progenitors, the molecular circuits controlled by the Notch pathway that balance ILC subsets, and how these pathways influence hepatocellular carcinoma progression and inflammatory diseases. Her team combines single-cell approaches, genetically modified models, and human tissue analysis to dissect microenvironmental cues shaping ILC fate. Publication Trends: Between 2020 and 2024 her work has appeared in leading journals such as Cell Reports , Immunity , EMBO Journal , Blood , and Frontiers in Immunology . The studies cluster around four main axes: (1) ILC differentiation and ontogeny, (2) Notch-mediated regulation of ILC and NK cells, (3) tumour-immune interactions in hepatocellular carcinoma, and (4) inflammatory modulation of lymphocyte development in metabolic and wound-healing contexts. Scientific Awards & Recognition: Prime d’Excellence Scientifique (PES) 2012-2016 PEDR Award 2007-2011 INSERM CSS7 third-rank distinction 2014 Fellowships from Ligue Nationale contre le Cancer, MRC Canada, Ontario Cancer Institute, and French Ministry of Research Grants & Advising: She has served as coordinator or collaborator on >15 major grants (ANR, ARC, INCA, FACCTS, USPC, ABM, PTR), funding post-doctoral and doctoral students as well as collaborative international projects. She regularly sits on HDR and PhD juries, ANR panels, and foreign funding agencies (DFG). Labs & Teams: Her Lymphopoiesis Unit at Institut Pasteur hosts the “ILC Development and Inflammation” group, currently comprising PhD students, engineers, and technicians. The team is embedded within the wider Pasteur Immunology Department and benefits from institute-level platforms such as Single-Cell Biomarkers and advanced imaging core facilities.

• Innate lymphoid cell biology
• Notch signaling
• Hepatocellular carcinoma
• +4 more

Brice Rotureau is a Director of Research at the Institut Pasteur in Paris and leads the Trypanosome Transmission Group. He also serves as the Director of the Parasitology Unit at the Institut Pasteur of Guinea in Conakry. His research focuses on the development, transmission, diagnostics, and eco-epidemiology of trypanosomatid parasites responsible for neglected tropical diseases such as Human African Trypanosomiasis (sleeping sickness). His research interests include Molecular and cellular biology of Trypanosoma species Parasite transmission mechanisms in tsetse flies Development of CRISPR-based diagnostic tools (e.g., SHERLOCK platform) Epidemiology and zoonotic reservoirs of trypanosomatid diseases Host-pathogen interactions and tissue tropism (skin, adipose) The recent articles highlight a strong trend toward innovative diagnostics (SHERLOCK), metabolic and signaling pathways in parasite development, and the role of alternative reservoirs (skin, adipose tissue) in disease persistence. His work integrates molecular biology, imaging, and field epidemiology to address both fundamental and public health aspects of parasitic diseases. Scientific awards include: Launois Prize, French Academy of Medicine (2023) Deschiens Prize, French Academy of Medicine (2017) Epidaure Prize, Foundation for Medical Research (2008) Annual prize, French Society of Parasitology (2011) Evian-les-Bains Prize, French Academy of Medicine (2009) Brice Rotureau actively advises on research strategy and grant evaluation, serving as an Associate Editor for Microbiol Spectrum and Trop Med Infect Dis , and as a reviewer and evaluator for major funding bodies (ERC, Wellcome Trust, ANR). He mentors students and contributes to teaching parasitology at multiple institutions. His leadership extends to international collaborations, including membership in the SAB of the LAMIVECT consortium and participation in WHO expert panels. He currently coordinates or partners in several ANR and BMGF-funded research projects. He is involved in the HistoPathology Core Facility and Image Analysis Hub at the Institut Pasteur, contributing to the advancement of digital pathology and quantitative histopathology through initiatives like the D-Patho project.

• Trypanosomatid parasites
• Neglected Tropical Diseases
• Parasite transmission
• +7 more

Fanny Lanternier is a prominent researcher at the Pasteur Institute in Paris, France, specializing in medical mycology and the epidemiology of invasive fungal infections. She serves as Principal Investigator for the "Databases on the epidemiology of invasive fungal infections in France" project and is an active member of the French Mycoses Study Group, a nationwide network of clinicians and microbiologists diagnosing and treating patients with fungal infections. Her research focuses on the epidemiology, diagnosis, and treatment of histoplasmosis, cryptococcosis, mucormycosis, and other invasive fungal diseases, particularly in immunocompromised populations including patients with autoimmune diseases, HIV, and primary immunodeficiencies. Dr. Lanternier's work demonstrates strong trends toward large-scale collaborative epidemiological studies with clinical translation potential. Her recent publications show increasing emphasis on mold-positive blood cultures, cryptococcosis in HIV-negative individuals, and fungal infections in patients with specific immune deficiencies like STAT3 Hyper-IgE Syndrome. She collaborates extensively with Olivier Lortholary, Dea Garcia-Hermoso, and other leading experts in the field. Dr. Lanternier contributes to the Medical Mycology MOOC (Massive Open Online Course) directed by Dea Garcia-Hermoso and Olivier Lortholary, demonstrating her commitment to education and knowledge dissemination in the field of medical mycology.

• Medical Mycology
• Fungal Infections
• Epidemiology of Fungal Diseases
• +6 more

Dr. Aude Nassif is a dermatologist and researcher at the Pasteur Institute Medical Center in Paris, where she has worked since 2000. She specializes in Hidradenitis Suppurativa (HS) research and clinical management, serving as Principal Investigator for the REVE-Pasteur project, a register of HS patients at the Pasteur Institute Medical Center. Dr. Nassif has developed expertise in both the genetic and microbiological aspects of HS, collaborating extensively with researchers from Necker-Enfants Malades hospital. Medical studies at University of Angers (1975-1982) Residency in Dermatology at Reims and Tarnier-Cochin, Paris (1982-1988) Board certified in Dermatology (1988) Chief residency in Dermatology at Rouen (1988-1989) Medical training in USA (1989-1992), including fellowship at Oregon Health Sciences University with Dr. Jon Hanifin Worked as dermatologist at Croix-Saint Simon Hospital and Tarnier-Cochin Hospital (1993-2003) Dr. Nassif's primary research focus is on Hidradenitis Suppurativa, with particular interest in the genetic and microbiological aspects of the disease. She has been involved in HS genetic studies since 2006 and microbiological studies since 2007. Her work has led to the development of a new antibiotic strategy targeted according to microbiology of lesions, allowing prolonged remission of HS in combination with surgery. She also investigates hormonal influences and sexual dimorphism in HS as part of the SHINE-HS project and collaborates on metabolomic and immunologic studies of HS lesions. Dr. Nassif's publication record demonstrates consistent focus on advancing HS understanding and treatment approaches. Her research spans genetic studies, microbiological analyses, clinical treatment strategies, diagnostic improvements, and disease severity assessment. She has contributed to the development of new antibiotic protocols and scoring systems for HS, while investigating paradoxical reactions to biologic agents in HS patients. Her work often involves collaborative efforts across multiple French institutions. Dr. Nassif has secured multiple research grants related to HS, with the team obtaining 8 academic grants over the past 10 years (3 from SFD, 3 from FRM, 1 PHRC and 1 from Pasteur Institute). She collaborates with several prominent researchers including Dr. Maia Delage Toriel, Dr. Join-Lambert, Dr. Duchatelet, and Pr. Hovnanian. Her laboratory work focuses on understanding the complex interplay between host genetics, microbiome, and immune responses in HS pathogenesis.

• Hidradenitis Suppurativa
• Atopic Dermatitis
• Dermato-allergology
• +4 more

Dr. Maia Delage-Toriel is a Physician Scientist in the Dermatology Department at Institut Pasteur Medical Center , specializing in Hidradenitis Suppurativa (HS) and related inflammatory skin diseases. She leads clinical trials like the ABCESS2 and ROXANE projects while collaborating on grants from institutions including SFD , FRM , and Pasteur Institute . Education: Medical studies at University of Necker (1997-2005) Residency in Dermatology at CHRU Tours (2005-2009) Diplôme Interuniversitaire (DIU) of Skin Cancerology (2008-2009) Her research focuses on the interplay between microbiota, biofilms, and immune responses in HS pathogenesis, with recent work on tryptophan metabolism dysregulation and genetic factors via the SHINE-HS and DeciVERNEUIL projects. She co-leads metabolomic studies to identify HS biomarkers and maintains a prospective patient cohort for longitudinal analysis. Scientific Contributions include 10 peer-reviewed publications (2015-2020) spanning clinical trials, microbiome profiling, disease scoring systems ( IHS4 ), and paradoxical effects of biologics. Her work has secured 8 academic grants over a decade, including funding from French Dermatology Society (SFD) and Pasteur Institute.

• Hidradenitis Suppurativa
• Inflammatory Diseases
• Microbiota
• +3 more

Lionel Adès is a Professor of Hematology at Hôpital Saint-Louis, affiliated with Université de Paris, where he has maintained continuous employment since January 1997. His clinical and research activities focus on myeloid malignancies, particularly myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), and acute promyelocytic leukemia. Dr. Adès' research interests center on the molecular characterization of myelodysplastic syndromes, risk stratification systems, and novel therapeutic approaches for high-risk hematologic malignancies. His work prominently features investigations into TP53-mutated diseases, VEXAS syndrome (a recently described entity involving UBA1 mutations), and treatment response prediction using genomic markers. He has made significant contributions to understanding the role of specific somatic mutations in treatment response and disease progression. Analysis of his recent publication record (2023-2025) reveals a strong focus on precision medicine approaches in myeloid malignancies. His work spans clinical trials of novel agents like eprenetapopt for TP53-mutated diseases, real-world evidence studies of luspatercept in ring sideroblast-positive MDS, and innovative approaches to risk assessment including the IPSS-M scoring system. He frequently collaborates with international consortia including the Groupe Francophone des Myélodysplasies (GFM) and European organizations like EBMT and European LeukemiaNet. Dr. Adès serves as an active peer reviewer for major hematology journals, with documented reviews for Leukemia (8 reviews), Blood reviews, Annals of hematology, and others. His publication record demonstrates leadership in developing clinical guidelines and consensus statements, particularly through his involvement with European expert panels. While specific grant information isn't provided in the text, his numerous multi-center clinical trials suggest substantial research funding support. His laboratory work appears to include investigations into the bone marrow microenvironment, as evidenced by publications on 3D artificial marrow organoid systems for studying hematopoiesis. He collaborates extensively with researchers across Europe and maintains active involvement in both clinical care and translational research, bridging the gap between laboratory discoveries and patient applications.

• acute myeloid leukemia
• acute promyelocytic leukemia
• myelodysplastic syndromes
• +3 more

Thierry Maugard is a University Professor (Exceptional Class) at La Rochelle University, serving as Head of the Biotechnologies and Chemistry of Bioresources for Health Team (BCBS, UMR-LIENSs-CNRS-7266) and Director of the BIOAQTIV Platform. He leads the Joint PHYTOMAR Laboratory with Valbiotis and holds significant institutional roles including membership in CNU section 64 (College A) and board positions with the League Against Cancer (Charente-Maritime) and ADEBIOTECH (French Biotechnology Network). His research focuses on bioprocesses for transforming marine and agricultural resources into health, food, and cosmetic applications, specifically targeting biomolecules regulating pathological processes like cancer, diabetes, and hypertension. Key research areas include understanding mechanisms of action for hydrolases, peptides, oligosaccharides, polyphenols, and pigments in biological regulation, and developing natural-origin formulations for active ingredients—particularly algae-sourced compounds for skin aging and metabolic syndrome interventions. Analysis of recent publications reveals strong emphasis on marine biotechnology (especially algal polysaccharides), enzyme engineering for oligosaccharide synthesis, nutraceutical development for metabolic disorders, and biomaterial applications in drug delivery. His work bridges fundamental biochemistry with industrial applications across pharmaceuticals, nutraceuticals, and cosmetics. 99 publications in international journals with h-index 28 (Scopus) 13 patents and 2 licenses demonstrating translational impact Member of CNU section 64 and scientific referent for CNRS INEE Board member of League Against Cancer (Charente-Maritime) Professor Maugard actively supervises doctoral research with 16 thesis students (15 completed, 1 ongoing) and has mentored 31 Master's and 14 engineering students. His leadership extends to the BIOAQTIV Platform for advanced biotechnology applications and collaborative PHYTOMAR Laboratory focused on marine bioresources.

• Biotechnologies
• Biocatalysis
• Marine Biotechnology
• +4 more

Pr. Sandrine Lorimier serves as a Professor (PU-PH) at the Faculty of Dentistry, University of Reims Champagne-Ardenne. She holds multiple administrative roles including elected member of the Management Council and Finance Commission of the Dental Faculty, Vice-President of the Pedagogical Commission since 2012, and elected Vice-President of the National College of Teachers in Biological Sciences of Odontology (CNESBO). She coordinates the Forum of Young Researchers in Dentistry and oversees PACES Odontology programs in Reims and Amiens. Her research spans periodontology, oral biology (dental embryology/histology), inflammatory diseases (Hidradenitis Suppurativa, periodontal diseases), and medical infrared thermography applications. She pioneers regenerative medicine approaches using peptides for skin/periodontal tissue repair and develops diagnostic tools via biospectroscopy/chromatography. Her work bridges dentistry, dermatology, and bioengineering to address complex inflammatory conditions through interdisciplinary collaboration. Recent publications demonstrate clinical applications of infrared thermography in Hidradenitis Suppurativa treatment and peptide-based dermal regeneration, highlighting translational research from laboratory to surgical practice. These studies emphasize diagnostic innovation and tissue engineering solutions for inflammatory pathologies. She co-supervises doctoral and master's theses while mentoring dental surgery doctorate candidates. Her research integrates clinical practice with laboratory investigations through collaborations with EA 4694 GRESPI, UMR CNRS 7369 MEDyC (Extracellular Matrix and Cell Dynamics), and INRAP (archaeological population studies). She actively contributes to scientific discourse as a reviewer for journals including Journal of Cell Biochemistry and Wound Repair and Regeneration.

• Periodontology
• Oral Biology
• Inflammatory Diseases
• +4 more

Nicolas Bridiau is a Lecturer-researcher at La Rochelle University , affiliated with the BCBS team and collaborating with institutions like University of Nantes and LIENSs UMR 6250 CNRS-ULR. He holds a Doctoral thesis (2005-2008) and a Research Master's in Biochemistry (option: Biochemistry, Molecular and Cellular Biology, and Bio-organic Chemistry, 2004-2005). Doctoral thesis: 2005-2008 Research Master's: Biochemistry, Molecular and Cellular Biology, and Bio-organic Chemistry (2004-2005) His research focuses on Chemoenzymatic synthesis of tumor antigens and glycopeptides , particularly SLex analogs linked to tyrosine analogs for potential anti-metastatic applications . He investigates glycosyl-hydrolases and lipases in unconventional environments for synthesizing immunomodulatory carbohydrates . Collaborations include Michel Dion (University of Nantes) and Laurent Picot (La Rochelle University). Recent publications highlight his work on marine-derived polysaccharides with anti-heparanase properties, bioactive ulvans for skin regeneration, and enzyme immobilization techniques. Patents involve marine polysaccharide-based cosmetics and anticoagulant agents . His work bridges biochemical synthesis , marine biotechnology , and biomedical applications . Collaborations span multiple institutions, with key contributions to marine bioproducts and enzyme engineering for industrial applications.

• Chemoenzymatic synthesis
• Tumor antigens
• Glycopeptides
• +5 more

Alain Hovnanian leads a research team focused on genetic skin diseases, particularly dystrophic epidermolysis bullosa, Netherton syndrome, and Darier disease. His work integrates molecular mechanisms, therapeutic development (gene therapy, protein replacement, and small molecules), and clinical trials. He is affiliated with INSERM, leading studies on gene correction using lentiviral vectors, CRISPR/Cas9, and mesenchymal stem cells. His team also investigates inflammatory pathways (IL-17/IL-36, TSLP) and protease inhibitors for Netherton syndrome. Collaborations include developing KLK5/7 inhibitors and mTOR inhibitors for epidermolysis bullosa. Preclinical models include humanized mice and xenograft systems to test therapies. Research spans from identifying modifier genes in DEB fibrosis to repurposing drugs like diacerein. His group actively participates in clinical trials such as the EBGene ex vivo gene therapy trial for recessive DEB. Key areas include understanding ER stress in Darier disease and advancing therapies targeting calcium homeostasis. Team members include postdocs, PhD students (e.g., Mathilde Bonnet des Claustres), and engineers. Ongoing projects address hidradenitis suppurativa, psoriasis, and Olmsted syndrome through exome sequencing and functional studies. Lab focuses on translating molecular insights into treatments, including biotherapies and pharmacological approaches.

• Genetic Disorders
• Dermatology
• Gene Therapy
• +3 more

Nicolas Guillot is an Assistant Professor in the Biosciences Department at INSA Lyon, where he also serves as deputy director of the department and director of the Animal Facility. His academic journey began with a PhD in vascular biology from University Lyon 1 in 2008, followed by postdoctoral training in New York City focusing on vascular inflammation and angiogenesis in sickle cell disease. Institution: INSA Lyon Department: Biosciences Position: Assistant Professor Leadership Roles: Deputy Director of Biosciences Department, Director of Animal Facility His research centers on vascular biology, particularly the endothelial response to mechanical stress and red blood cell-endothelium interactions in sickle cell disease. He also investigates blood rheology, vascular inflammation, and the impact of metabolic conditions on vascular function. His work has important implications for understanding thrombosis, microvascular complications, and cardiovascular pathologies in chronic diseases. The trends in his recent publications (2016–2025) reveal a consistent focus on vascular and hematological pathologies, particularly sickle cell disease, blood viscosity, microvascular dysfunction, and related conditions such as diabetes and CKD. His collaborative, interdisciplinary research spans physiology, hematology, cardiology, and molecular biology, often involving international teams and appearing in high-impact journals like The Lancet Regional Health - Americas , Blood , and Frontiers in Physiology . Nicolas Guillot has made significant contributions to understanding: The role of omega-3 fatty acids in reducing platelet activity and thrombosis risk The involvement of the TGFbeta/BAMBI pathway in vascular restenosis and angiogenesis How shear forces alter endothelial lipid metabolism Increased vascular risk in diabetic patients with sickle-cell trait He teaches cardiovascular physiology and pharmacokinetics and leads research supported by multiple grants, collaborating with institutions in the USA, Germany, and the UK. He supervises research within the [VBRBC] team at INSA Lyon and oversees animal research facilities, ensuring ethical and scientific rigor in experimental models.

• Vascular Biology
• Endothelial Physiology
• Sickle Cell Disease
• +7 more