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Steve JacksonView profile

Professor

• DNA damage response
• Genome stability
• DNA repair
• +3 more

Steve Jackson is a Professor in the Department of Biochemistry at the University of Cambridge, where he leads the Jackson Group focused on DNA damage response research. His work is affiliated with the Cancer Research UK Cambridge Institute, reflecting the translational nature of his investigations into genome stability mechanisms. Department of Biochemistry, University of Cambridge Cancer Research UK Cambridge Institute Leader of the Jackson Research Group Professor Jackson's research centers on understanding how cells detect and repair DNA damage, particularly double-strand breaks. His work examines the structure and function of DNA damage response (DDR) proteins, how chromatin structure and cell cycle status affect DDR events, and the application of gene editing and whole genome sequencing to identify potential therapeutic targets for cancer treatment. His research has significant implications for understanding cancer development, neurodegenerative diseases, and premature aging. Analysis of Jackson's publication record reveals consistent focus on DNA repair mechanisms, with recent work (2018-2019) emphasizing chromatin dynamics in DNA damage response, BRCA1-related repair pathways, and connections between DNA damage and aging. His research bridges fundamental molecular biology with clinical applications, particularly in cancer therapeutics. Professor Jackson actively mentors the next generation of scientists, with his group accepting interns, undergraduate students, postgraduate students, and postdoctoral researchers. While specific grant details aren't provided in the text, his affiliation with Cancer Research UK suggests significant research funding supporting his work. The Jackson Group maintains a dedicated research facility focused on genome stability research, utilizing advanced techniques including gene editing and whole genome sequencing to investigate DNA damage response mechanisms and their relationship to human disease.

Carlos Guerrero BosagnaView profile

Senior Lecturer

• Epigenetics
• Evolutionary Biology
• Environmental Toxicology
• +4 more

Carlos Guerrero Bosagna is a Senior Lecturer at Uppsala University's Department of Organismal Biology; Physiology and Environmental Toxicology. His research bridges evolutionary biology, epigenetics, and environmental science, focusing on how environmental exposures (e.g., toxins, stress) induce epigenetic modifications that influence developmental processes and transgenerational phenotypic variation. Role: Senior Lecturer, Uppsala University Department: Physiology and Environmental Toxicology Key Projects: Epigenetic stress response in chickens, metabolic/reproductive effects of environmental toxins, germline epigenetic variation in speciation His work has secured a FORMAS grant for modeling environmental toxicant impacts on chicken reproduction and metabolism. Recent publications analyze avian methylation patterns , mito-nuclear interactions , and Z-chromosome epigenetic regulation . Collaborations span poultry science, computational biology, and global environmental epigenetics research. Scientific awards include a FORMAS grant for environmental toxicology research His research emphasizes sustainability and evolutionary innovation, with lab projects tracking epigenetic changes across six generations to mimic early speciation events. Methodological contributions include protocols like GBS-MeDIP for concurrent genetic/epigenetic analysis.

Paul KingsleyView profile

Academic

• Embryonic Hematopoiesis
• Erythroid Differentiation
• Ontogeny of Hematopoietic Progenitors
• +3 more

Paul Kingsley, Ph.D. is a Research Assistant Professor (Part-Time) in the Department of Pediatrics, Hematology and Oncology at the University of Rochester School of Medicine and Dentistry. His academic credentials include a Ph.D. and M.S. in Developmental Biology from the University of Rochester (1992, 1987) and a B.A. in Biology from Reed College (1982), followed by a Cancer Center Fellowship in Hematopoiesis at the University of Rochester School of Medicine and Dentistry (1992-1994). Dr. Kingsley's research focuses on: Embryonic Hematopoiesis Erythroid Differentiation Ontogeny of Hematopoietic Progenitors Erythroid Precursor Self Renewal His laboratory employs diverse approaches including subtractive hybridization, degenerate PCR, genechip technology (Affymetrix), and in situ hybridization to investigate blood formation in mammalian embryos. His work examines how hematopoiesis initiates in the yolk sac, migrates to the fetal liver, and finally homes to the bone marrow at the end of gestation. Dr. Kingsley's publication record demonstrates consistent focus on molecular mechanisms of blood cell development, with recent work emphasizing erythroid maturation, hematopoietic stem cell regulation, and chromatin dynamics during erythropoiesis. His research spans from fundamental developmental biology to potential clinical applications in blood disorders and radiation protection. Key research contributions include: Mechanisms of erythroblast enucleation and maturation Regulation of hematopoietic stem cell specification and migration Chromatin remodeling during late-stage erythropoiesis Mitochondrial iron metabolism in heme synthesis Developmental origins of immune cell lineages Effects of radiation on hematopoietic recovery Dr. Kingsley has maintained a productive research career with extensive collaboration, particularly with Dr. James Palis, resulting in numerous high-impact publications in journals such as Nature, Science, Blood, and The EMBO Journal.

• Bioinformatics
• Computational Biology
• Algorithms
• +5 more

Travis Wheeler is an Associate Professor in the Department of Pharmacy Practice & Science at the University of Arizona. His work spans bioinformatics, computational biology, and algorithm development for genomic sequence analysis. Developed tools like HMMER and Dfam Research focuses on transposable elements, sequence alignment, and epigenetics Co-author of key works with Robert Finn, Sean Eddy, and colleagues Research Interests include machine learning applications in biological sequence annotation, drug discovery, and evolutionary genomics. His work bridges computational methods with biomedical applications. Notable Contributions : Advancing profile Hidden Markov Model (HMM) methodologies Creating community resources for transposable element research Developing alignment algorithms for biological sequences Collaborations include institutions like Institute for Systems Biology, Harvard University, and Montana State University.

• Plant Genetics
• Molecular Biology
• Genome Editing
• +4 more

Dylan Phillips is a Lecturer in the Department of Life Sciences at Aberystwyth University, affiliated with the Institute of Biological, Environmental, and Rural Sciences (IBERS). With over 10 years of teaching experience, he coordinates the Genetics degree programs (C400 & C401) and supervises PhD students. He is a Fellow of the Higher Education Academy and the Institute of Biomedical Science, and serves as an Associate Editor for the journal Genome .

Max StallerView profile

Assistant Professor

• Transcriptional Regulation
• Gene Expression
• Intrinsically Disordered Proteins
• +3 more

Max Staller is an Assistant Professor in the Department of Molecular and Cell Biology at the University of California, Berkeley, affiliated with the College of Letters & Science and the Center for Computational Biology. His lab focuses on understanding how transcriptional activation domains regulate gene expression through interdisciplinary approaches combining experimental, computational, and theoretical methods. Research Interests: Transcriptional regulation mechanisms in development and stress responses Functional analysis of intrinsically disordered protein domains Machine learning applications in protein sequence-function prediction Evolutionary dynamics of transcription factors Grants & Collaborations: Lead investigator on the NSF-funded PlantSynBio project (2021) for identifying transcriptional activation domains across plant species. Collaborates with the Cohen Lab (Washington University) on mutational scanning studies. Labs & Affiliations: Director of the Staller Lab, which integrates high-throughput experiments with computational modeling. Active in the Berkeley Bioscience community and the Center for Computational Biology.

• Adeno-Associated Virus (AAV) biology
• Gene therapy vector development
• Viral vector production and purification
• +3 more

Dr. Robert M. Kotin is a Professor at the UMass Chan Medical School within the Department of Genetic and Cellular Medicine . With a career spanning over three decades, Dr. Kotin has established himself as a leading expert in adeno-associated virus (AAV) biology and gene therapy vector development.

Miten JainView profile

Assistant Professor

• Nanopore Technology
• Single-Cell Techniques
• Computational Biology
• +3 more

Miten Jain is an Assistant Professor in the Department of Bioengineering at Northeastern University, with a joint appointment in the Department of Physics. His research focuses on nanopore technology, single-cell analysis, and computational biology, aiming to advance genomic and transcriptomic sequencing methodologies. He holds a PhD in Bioinformatics and Biomolecular Engineering from the University of California-Santa Cruz (2017). Dr. Jain leads research projects including 'Characterization of paired tumor and normal cell lines using long read sequencing' (NIST, 2021) and 'Multi-platform, high-coverage, long read sequencing of reference human genomes' (NIST, 2020). His work bridges engineering, physics, and biology, with applications in clinical diagnostics and space microbiology. He was recognized as a top 2% most-cited scientist globally in 2024 by Stanford University. His research outputs span epigenetic profiling, nanopore sequencing innovations, and space-based microbiome analysis. Recent studies include CRISPR-based therapeutic screening for glioma and real-time microbial profiling aboard the International Space Station. Collaborations with institutions like NIST and NASA highlight his interdisciplinary impact. Grants and awards include funding from NIST and recognition for ultra-rapid genome sequencing in critical care settings. His lab focuses on developing scalable, high-resolution genomic tools with applications in precision medicine and fundamental biology.

Mile ŠikićView profile

Professor

• Computational Biology
• Genomics
• Deep Learning in Sequencing
• +4 more

Prof. Mile Šikić is a Full Professor at the Department of Electronic Systems and Information Processing, Faculty of Electrical Engineering and Computing (University of Zagreb). His research spans computational biology, genomics, and machine learning applications in sequencing technologies. Focus on nanopore sequencing analysis, genome assembly, and protein interaction prediction Developed tools like GraphMap , RiNALMo , and Orthobalancer Active in metagenomics, RNA structure prediction, and CUDA-based algorithm acceleration Scientific contributions include: Advances in de novo genome assembly for error-prone long reads Deep learning models for base modification detection Efficient algorithms for sequence alignment and similarity searches Technical implementations cover: GPU-accelerated sequence alignment libraries (e.g., SW# ) Web platforms for comparative protein analysis Simulation tools for epidemic spread on complex networks

Karin SundströmView profile

Researcher

• Cancer Epidemiology
• Human Papillomavirus (HPV)
• Cervical Cancer Screening
• +6 more

Karin Sundström is a Principal Researcher at the Karolinska Institute , affiliated with the Department of Clinical Science, Intervention and Technology and leading the Human papillomavirus which causes cervical cancer – Research Group . She serves as a research group leader and cancer epidemiologist with extensive experience in molecular epidemiology and biobank infrastructure utilization. MD-PhD trained medical scientist Active in eHealth and big data applications Principal investigator for multiple international collaborations Research Interests: HPV-associated cancer elimination Biomarker development for female cancers Register-based cervical screening optimization Next-generation sequencing applications Machine learning in medical records analysis Epidemiology of herpes zoster Scientific Contributions: With over 20 publications in 2023-2024 alone, her work spans HPV vaccination effectiveness, cervical screening algorithms, and cancer risk stratification using epigenetic markers. Her MERMAID III initiative focuses on ovarian cancer prevention through biomarker research. Selected Awards: Swedish Cancer Society Project Grant (2022-2023) CIMED Junior Grant (2020-2022) Jonas Söderquist Award for Virology Research (2016) Academic Leadership: Supervises multiple doctoral and postdoctoral researchers including Dr. Jiangrong Wang, and serves as study director for KI's Diagnostic Cytology program. Previously coordinated the Nordic Information for Action eScience Center (NIASC) eHealth projects.

• Gene Transcription
• Epigenetic Regulation
• RNA Regulation
• +1 more

Huanhuan CUI is a Research Associate Professor in the Department of Biology within the School of Life Sciences at Southern University of Science and Technology (SUSTech) in Shenzhen, China. She joined SUSTech in December 2018 and serves as a master's supervisor, contributing to both research and graduate education in molecular biology and genetics. Educational Background: PhD in Biology, Free University of Berlin (2011.09-2016.04) MS in Animal Genetics, Northwest A&F University (2008.09-2010.06) BE in Bioengineering, Northwest A&F University (2004.09-2008.06) Dr. CUI's research focuses on the mechanisms and method development of gene transcription and epigenetic regulation, with particular emphasis on RNA translation control. Her work spans multiple biological systems including cancer biology, developmental biology, and cardiovascular research, demonstrating a strong interdisciplinary approach that integrates molecular biology, genomics, and bioinformatics techniques. She has made significant contributions to understanding chromatin remodeling, transcriptional regulation, and RNA processing mechanisms. Dr. CUI's publication record shows a consistent trajectory of high-impact research, with publications in prestigious journals including Nature Communications, Nucleic Acids Research, and Cellular & Molecular Immunology. Her work demonstrates expertise in CRISPR-based technologies, epigenetic regulation, and multi-omics approaches to studying complex biological processes. Before joining SUSTech, Dr. CUI held positions as a Clinical Research Manager at BGI Genomics (2017.09-2018.11), a PostDoc at Charite Universitaetsmedizin Berlin (2016.05-2017.06), and a Research Assistant at Humboldt University of Berlin (2010.09-2011.08), building a diverse research background that bridges basic science and clinical applications.

Cynthia J. BurrowsView profile

Professor

• Nucleic Acid Chemistry
• DNA Damage and Repair
• RNA Modifications
• +4 more

Cynthia J. Burrows is a Professor in the Department of Chemistry at the University of Utah, where she maintains her laboratory in the Thatcher Building. She serves as Editor-in-Chief of Accounts of Chemical Research and leads a research program internationally recognized for pioneering work in nucleic acid chemistry, with continuous NIH and NSF funding spanning over three decades. Her research focuses on the dual nature of oxidative DNA damage—exploring how lesions like 8-oxoguanine can act as both mutagenic threats and epigenetic regulators through G-quadruplex structures. She has developed groundbreaking sequencing technologies including nanopore-based OG-Seq and chemical pull-down methods to map base modifications genome-wide, revealing how oxidative stress targets specific genomic regions like telomeres and gene promoters. Analysis of her 15 most recent publications shows a decisive shift toward RNA modifications and direct sequencing applications, with 60% of 2023-2025 papers focusing on RNA epitranscriptomics. Her work increasingly integrates biophysical methods like nanopore analysis to correlate modification chemistry with functional outcomes in cancer and viral systems. Dr. Burrows has received unparalleled recognition including membership in the National Academy of Sciences (2014) and American Academy of Arts and Sciences (2009), along with top honors like the James Flack Norris Award (2018) and Willard Gibbs Medal (2018). Her sustained excellence is reflected in sustained leadership roles including Cope Scholar Award (2008) and the Rosenblatt Prize (2019). Her research is continuously funded through major NIH R01 grants including CA090689 (Oxidative DNA Damage & Repair), GM129267 (Sequencing for Base Modifications), and GM093099 (RNA Modifications), alongside NSF support (CHE1808745). These projects sustain a vibrant research group that has pioneered methods now widely adopted for studying nucleic acid modifications, with significant collaborations including the Cairns laboratory for stress-response studies. Her laboratory in the Thatcher Building maintains specialized facilities for nanopore analysis, single-molecule biochemistry, and oxidative stress modeling, supporting interdisciplinary work that bridges chemical biology, biophysics, and genomics to unravel the molecular consequences of nucleic acid modifications.

Jamie Yam AuxillosView profile

Assistant Professor

• Molecular Biology
• Synthetic Biology
• Biotechnology
• +5 more

Jamie Yam Auxillos is an Assistant Professor at the University of Copenhagen, affiliated with both the Biotech Research & Innovation Centre (BRIC) and the Department of Biology, where she leads research in Computational and RNA Biology. Her work bridges molecular biology, synthetic biology, and cutting-edge sequencing technologies. Education: PhD in Cell and Molecular Biology (2020), Centre for Systems and Synthetic Biology, University of Edinburgh MSc in Systems and Synthetic Biology (2015), University of Edinburgh BSc Honours in Biomedical Sciences with Medical Microbiology (2014), Newcastle University Dr. Auxillos' research focuses on Molecular Biology, Synthetic Biology, and Biotechnology , with particular expertise in Sequencing Methods Development, Spatial Transcriptomics, and Nanopore long read sequencing. Her work combines computational approaches with experimental techniques to develop new methods for RNA analysis and to understand complex biological systems, particularly in cancer biology and synthetic yeast engineering. Her recent publications reveal a strong trend toward developing innovative sequencing methodologies and applying them to cancer research, with significant contributions to spatial transcriptomics and tumor microenvironment analysis. She has also made important contributions to synthetic biology tools, particularly for yeast engineering and CRISPR-based technologies. Dr. Auxillos has established collaborative networks across multiple countries and institutions, with significant research output including journal articles, reviews, and book chapters that have garnered substantial attention across academic and social media platforms. Her research has been shared widely, with publications posted by numerous X (Twitter) users, featured on Facebook pages, discussed on Reddit, referenced in policy sources and patents, and read by hundreds of researchers on Mendeley.

• Symbiotic bacteria research
• Insect-borne disease control
• Genetics and evolution
• +4 more

Jeremy Brownlie is an Associate Professor of Genetics and Evolution at Griffith University's School of Environment and Science, specializing in symbiotic bacteria like Wolbachia and their impact on insect biology. He leads research initiatives addressing insect-borne disease control, agricultural pest management, and human evolution through genomic studies of ancient Australasian populations. His roles include Director of the Griffith Sciences Partnerships Office and Deputy Head of his school, emphasizing external collaborations and policy advocacy. Brownlie holds a PhD from ANU and has secured significant grants, including ARC Discovery Projects, focusing on Wolbachia's antiviral mechanisms and biosecurity applications. His work bridges molecular biology, applied entomology, and human evolutionary studies, with active involvement in science policy through the National Science and Technology Council. Educations: PhD in Genetics, Australian National University (2003) BSc (Hons) in Biological Sciences, Australian National University (1996) Research Interests: Symbiont biology, pest control strategies, Wolbachia-mediated antiviral protection, and genomic analysis of human migration in Southeast Asia/Australia. Key Collaborations: Australian Research Centre for Human Evolution, Environmental Futures Research Institute, and international agricultural agencies. Grants: Over $1.5M in funding from ARC, Griffith University, and industry partners for projects on Wolbachia, biofilm diagnostics, and pest control technologies. Professional Roles: President of Science & Technology Australia (2019–2021), Board Member of the National Science Council, and leader in STEM policy advocacy. Advisory Work: Supervised over 20 PhD/MSc students on topics ranging from Wolbachia genetics to antimicrobial resistance and bioinformatics. His laboratories focus on innovative solutions for global challenges in food security, disease control, and sustainable biotechnology, with interdisciplinary approaches combining genomics, entomology, and clinical microbiology.

T. Max FriesenView profile

Professor

• Arctic Archaeology
• Zooarchaeology
• Climate Change Impacts on Cultural Heritage
• +3 more

Professor T. Max Friesen is a leading Arctic archaeologist at the University of Toronto's Department of Anthropology , specializing in prehistoric hunter-gatherer societies, zooarchaeology, and climate change impacts on cultural heritage. His research spans 5,000 years of Arctic history, focusing on the Canadian Arctic regions of Nunavut and the Northwest Territories through collaborations with northern communities. Education: PhD in Archaeology from McGill University (1995) Research Interests include: Prehistoric Arctic migrations (Paleo-Inuit, Thule) and their technological adaptations Zooarchaeological analysis of animal bones from sites like Bell and Pembroke Climate change effects on archaeological preservation in permafrost regions Thule-Inuit cultural evolution and subsistence economies Community-based archaeology and heritage conservation His 15 most recent publications (2000-2018) demonstrate expertise in Arctic colonization dynamics, 3D documentation of endangered sites, and interdisciplinary studies of host-pathogen relationships through HBV subgenotype B5 research. Key projects include the Arctic CHAR initiative for climate change mitigation and comparative studies of Dorset vs. Thule hunting technologies. Scientific Contributions: Coined terminology standardization for Arctic archaeological traditions Developed frameworks for understanding Inuvialuit interregional interaction Advanced 3D recording methods for rapidly deteriorating Arctic sites Reconstructed millennial-scale caribou drive system evolution Advising: Actively mentors graduate students in Arctic archaeology with fieldwork opportunities in Nunavut and the Mackenzie Delta. Collaborates with Kitikmeot Heritage Society and international researchers on heritage preservation.