Spencer MuseView profile
Professor
Spencer Muse is a Professor in the Department of Statistics at North Carolina State University (NC State). He currently serves as the Director of the Statistics Undergraduate Program and the Director of the Bioinformatics Graduate Program. His work focuses on integrating statistical methodologies with biological data analysis, particularly in molecular evolution and genetics. He is affiliated with the Bioinformatics Research Center and contributes to interdisciplinary collaborations within the university. Spencer Muse holds a Ph.D. in Statistics and Genetics from NC State University, earned in 1993. His educational background merges advanced statistical training with genetic research, enabling him to address complex problems at the intersection of quantitative sciences and biology. His primary research interests include Bioinformatics , Statistical Genetics , and Molecular Evolution . He specializes in developing computational tools for evolutionary hypothesis testing and refining models that account for substitution rate variations and alignment errors. His work aims to improve the accuracy of selection analyses and parameter estimation in genetic datasets. Muse’s recent articles emphasize advancements in evolutionary analysis frameworks, including alignment error correction, substitution rate modeling, and software development (e.g., HyPhy, PowerMarker). These tools are widely used in studying viral, plant, and microbial genomes, enhancing the understanding of evolutionary processes and genetic diversity. No scientific awards or honors are explicitly mentioned in the provided information. His contributions to education and research administration highlight his role in shaping academic programs and fostering student development in quantitative biology and bioinformatics. In advising and grants, while no specific students or grants are listed, Muse’s leadership in undergraduate and graduate programs suggests active mentorship roles. His software contributions (e.g., HyPhy, PowerMarker) reflect significant grant-funded research. He is also part of the Administration Faculty group, overseeing departmental and programmatic activities. Muse is affiliated with the Department of Statistics and the Bioinformatics Graduate Program. His office is located in SAS Hall 5276, and he maintains a professional website linked to his profile.










