Tsukasa KamigakiView profile
Assistant Professor
Tsukasa Kamigaki is an Assistant Professor at the Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), Singapore. He leads a research laboratory focused on systems neuroscience, particularly the neural circuit mechanisms underlying executive function, working memory, and cognitive aging. His work integrates advanced techniques such as calcium imaging, optogenetics, and electrophysiology in mouse models. Ph.D. in Medicine, University of Tokyo School of Medicine (2010) B.S. in Neuroscience, University of Tokyo Graduate School of Arts and Sciences (2004) Dr. Kamigaki’s research centers on the prefrontal cortex and its role in executive control. He investigates how specific interneuron subtypes contribute to memory-guided behavior, how neural circuits reorganize during learning, and how aging and psychiatric disorders disrupt these circuits. His work bridges molecular, cellular, and systems-level neuroscience to understand cognitive function and dysfunction. His recent publications span high-impact journals including Nature Communications , Neuron , Nature Neuroscience , and Science . The articles reflect a strong trend in dissecting neuron-type-specific circuit functions, top-down modulation, and the neural basis of cognitive aging. His research increasingly focuses on translational models of cognitive decline. Human Frontier Science Program (HFSP) Long-Term Fellowship Uehara Memorial Foundation Postdoctoral Fellowship Japan Neuroscience Society Young Investigator Award MCB Outstanding Postdoc Award in Neurobiology at UC Berkeley Research Fellowships for Young Scientists (DC1), JSPS Dr. Kamigaki has mentored students and postdocs, and his lab actively pursues grants and collaborative research. He has delivered numerous invited talks at institutions such as RIKEN, UC Berkeley, and the University of Tsukuba. His lab, launched in 2019 at NTU, is equipped to study multiscale brain circuits and is contributing significantly to Singapore’s neuroscience research landscape. His research team, the Kamigaki Lab, investigates brain-wide and local circuit mechanisms for executive function. They utilize transgenic mouse models, in vivo imaging, and behavioral paradigms to explore how neural networks support cognition and how they deteriorate in aging and disease.
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