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Brendan A HarleyView profile

Professor

• Cell and Tissue Engineering
• Biomaterials
• Extracellular Matrix Analogs
• +3 more

Brendan A. Harley is the Robert W. Schaefer Professor in Chemical and Biomolecular Engineering at the University of Illinois at Urbana-Champaign (UIUC), with a joint appointment in the Carl R. Woese Institute for Genomic Biology. His research focuses on developing biomaterials to replicate complex tissue microenvironments, enabling insights into cell behavior during development, disease, and regeneration. He holds leadership roles in academic and professional organizations, including editorial positions for Science Advances and Tissue Engineering . Harley earned his SB from Harvard University (2000), SM/ScD from MIT (2002, 2006), and completed postdoctoral studies at Boston Children’s Hospital. **Education**: Sc.D., Massachusetts Institute of Technology, 2006 S.M., Massachusetts Institute of Technology, 2002 S.B., Harvard University, 2000 **Research Interests**: Engineering dynamic, spatially-patterned biomaterials to mimic extracellular matrices Regenerative repair of musculoskeletal tissues Biomaterial models of cancer microenvironments (e.g., glioblastoma) Artificial bone marrow systems for hematopoietic stem cell studies Harley’s work has produced over 100 peer-reviewed articles and co-authored a textbook Cellular Materials in Nature and Medicine . His lab develops materials for clinical applications, including osteochondral defect repair and craniofacial bone regeneration. Notable honors include the NSF CAREER Award (2013), AAAS Fellowship (2014), and AIMBE Fellowship (2019). **Awards/Recognition**: Fellow, AAAS (2014) Young Investigator Award, Society for Biomaterials (2014) Campus Distinguished Promotion Award, UIUC (2018) His research group emphasizes translational outcomes, with projects spanning biomaterial design, cancer modeling, and stem cell engineering. Collaborations include industry partners like Orthomimetics (acquired by TiGenix) and foundational studies on tumor microenvironments.

Johan Ulrik LindView profile

Associate Professor

• Additive Manufacturing
• Tissue Engineering
• Functional Materials
• +6 more

Johan Ulrik Lind is an Associate Professor and Groupleader at the Department of Health Technology, Technical University of Denmark. His research focuses on cutting-edge biomedical engineering solutions including tissue engineering, bioprinting, and microphysiological systems. He actively contributes to additive manufacturing and functional materials development. Current Affiliation: Department of Health Technology, DTU Research Areas: 3D bioprinting, hydrogel technologies, microsystems engineering Expertise: UN Sustainable Development Goals for health and well-being Lind's work spans additive manufacturing for tissue engineering, functionalized biomaterials , and dynamic microphysiological systems . His recent publications highlight innovations in hydrogel formulation, bioink development, and particulate drug delivery systems. Notably, he holds a patent for transparent bioink formulation. He supervises multiple PhD projects including: micro-perfused bioartificial ovaries, embedded bioprinting of perfusable vasculatures, and 3D printed microsystems for tissue actuation. His research portfolio demonstrates strong interdisciplinary collaboration across engineering, biology, and pharmaceutical sciences.

Benjamin SimonsView profile

Professor

• Stem Cell Biology
• Developmental Biology
• Cancer Biology
• +3 more

Benjamin Simons is the Royal Society EP Abraham Professor and Herchel Smith Professor of Physics at the University of Cambridge. He serves as Director of the Gurdon Institute, Senior Group Leader at the Gurdon Institute, Principal Investigator at the Cambridge Stem Cell Institute, and member of the Theory of Condensed Matter physics group. He is also a Fellow of St. John's College, Cambridge. His research integrates quantitative approaches from physics and mathematics with experimental biology to investigate stem cell fate regulation in tissue development, maintenance, and cancer pathogenesis. Research focuses on: Stochastic cell fate decisions in epithelial tissues Self-organization principles in tissue morphogenesis Single-cell lineage tracing and gene expression analysis Mathematical modeling of stem cell dynamics Cancer initiation through stem cell reprogramming Publication analysis reveals consistent themes: spatial dynamics of stem cell niches, mechanical regulation of cell fate, computational modeling of tissue organization, and evolutionary principles in cancer development. Recent work emphasizes in vivo lineage tracing, single-cell omics, and interdisciplinary approaches bridging physics and biology. Scientific Awards: Fellow of the Royal Society (FRS) Fellow of the Academy of Medical Sciences (FMedSci) Leads an interdisciplinary research group combining wet-lab experiments (lineage tracing, single-cell genomics) with theoretical modeling. Research supported by EPSRC, MRC, Wellcome Trust, Cancer Research UK, and Royal Society grants. Current projects include gliomagenesis mechanisms, spermatogenic wave regulation, and injury response pathways co-opted in cancer.

• Transplantation Immunology
• Immunological Tolerance
• Humoral Immunity
• +7 more

Professor Anita Chong is a distinguished immunologist at the University of Chicago's Pritzker School of Medicine, Department of Surgery-Transplant, where she leads groundbreaking research in transplantation immunology and tolerance mechanisms. Her laboratory has established herself as a leading authority in understanding the complex interplay between the immune system and organ transplantation. Dr. Chong's educational background includes a BS (Hons) from the University of Malaya, Malaysia, a PhD from Australian National University, Australia, and postdoctoral training at Tufts University, Boston, MA, followed by research associate work at the University of Arizona, Tucson, AZ. Her research program focuses on immunological tolerance and humoral immunity following allogeneic transplantation, with particular emphasis on understanding how infections prevent the induction of transplantation tolerance or destabilize established tolerance. Dr. Chong has developed innovative approaches to track defined populations of endogenous allospecific T cells (including CD4+ effectors, CD4+ Tregs, and CD8 effectors) and B cells, examining their behavior under conditions of rejection, memory/sensitization, and tolerance. She actively investigates memory alloreactive B cells in transplantation settings and has expanded her research into vaccination strategies to prevent infections as a means of stabilizing tolerance. Analysis of Dr. Chong's recent publications reveals a strong focus on cellular mechanisms of transplant tolerance and rejection, with particular emphasis on B cell biology, T regulatory cells, and the impact of infections on transplant outcomes. Her work increasingly incorporates multi-omics approaches and examines sex and gender differences in transplant outcomes, reflecting evolving trends in precision medicine within transplantation. Dr. Chong serves as Principal Investigator on multiple significant NIH-funded research projects, including R01AI182097 (Mechanistic studies on pregnancy-induced humoral sensitization in organ transplantation), R01AI148705 (Intrarenal B cells in acute kidney allograft rejection), and R01AI142747 (Deconstructing B cell transplantation tolerance). She has also served as Co-Principal Investigator on numerous collaborative grants. Her laboratory maintains extensive collaborations with Dr. Marisa Alegre studying infections and transplantation tolerance, Dr. Roger Sciammas at UC Davis, clinical transplant faculty at the University of Chicago and Ohio State University, Dr. Chris Montgomery on vaccination research, and Dr. Joel Collier at Duke University developing nanoparticulate adjuvant-free vaccines. These collaborative efforts have positioned her laboratory at the forefront of translational transplantation research with significant implications for clinical practice.

Steven SinkinsView profile

Professor

• Mosquito-borne diseases
• Arbovirus control
• Wolbachia symbiosis
• +4 more

Steven Sinkins is Professor in Microbiology and Tropical Medicine at the University of Glasgow, affiliated with the MRC-University of Glasgow Centre for Virus Research. His research focuses on controlling mosquito-borne diseases through innovative biological approaches. He directs the ANTI-VeC international research network and leads a team investigating microbial solutions to vector-borne pathogens. Research interests center on: Wolbachia symbionts for arbovirus control Microsporidian malaria-blocking symbionts in Anopheles mosquitoes Field implementation of biocontrol strategies against dengue and Zika viruses Molecular mechanisms of pathogen blocking in mosquito vectors Publication analysis reveals consistent focus on: Wolbachia-mediated viral inhibition mechanisms Field trials of novel vector control methods Genetic and symbiotic approaches to disease prevention Mosquito-symbiont-pathogen tripartite interactions Scientific recognition includes: Wellcome Trust Senior Research Fellowship (2006-2021) Leads multiple research grants: Wellcome Trust: Optimal implementation of Wolbachia programmes (2022-2027) Open Philanthropy: Microsporidia symbionts for malaria control (2020-2023) BBSRC: Genetic and symbiotic disease control strategies (2017-2020) Directs the Sinkins Group at the MRC-University of Glasgow Centre for Virus Research, collaborating internationally with partners in Malaysia, Kenya, Burkina Faso, and Australia to develop and implement novel vector control solutions.

Dave BridgesView profile

Associate Professor

• Nutrient sensing
• Cellular signaling
• Metabolic regulation
• +7 more

Dr. Dave Bridges is an Associate Professor in the Department of Nutritional Sciences at the University of Michigan School of Public Health . Trained as a molecular biologist and biochemist, his research focuses on the regulation of macronutrient metabolism with emphasis on obesity, diabetes, and cardiovascular disease. The Bridges Lab employs Drosophila , mouse, and human clinical models to investigate nutrient sensing pathways like mTORC1, glucocorticoid signaling, and precision nutrition approaches. Education: PhD, University of Calgary (2005) BS, University of Calgary (2000) Research areas include nutrient signaling pathways , stress-hormone interactions , and precision nutrition through ketogenic diet studies. Collaborations with Dr. Brigid Gregg examine breastmilk lipid variability and maternal health impacts. Recent work explores Bayesian statistical approaches for nutritional research, advocating for brms package implementation. Contact: Email: davebrid@umich.edu Phone: 734-764-1266 Address: 1415 Washington Heights, Ann Arbor, MI 48109

Megan Laura McCainView profile

Professor

• Biomedical Engineering
• Tissue Engineering
• Regenerative Medicine
• +4 more

Megan Laura McCain is a Professor of Biomedical Engineering at the University of Southern California (USC), with a secondary appointment in the Department of Stem Cell Biology and Regenerative Medicine at the Keck School of Medicine. She leads the McCain Lab, focused on developing microphysiological systems, particularly heart- and muscle-on-a-chip models, to study disease mechanisms and therapeutic responses. McCain holds affiliations with the Biomedical Engineering Society, American Society for Cell Biology, and American Heart Association. Her education includes a B.S. in Biomedical Engineering from Washington University in St. Louis (2006), a Ph.D. in Engineering and Applied Sciences from Harvard University (2012), and postdoctoral research at Harvard’s Wyss Institute. Notable awards include the American Heart Association Pre-doctoral Fellowship and Harvard’s Derek Bok Certificate of Distinction in Teaching. McCain’s research integrates tissue engineering, stem cell biology, and microfluidics to model complex biological systems. Her work emphasizes understanding how microenvironments influence cellular behavior in diseases like cardiovascular disorders and muscular dystrophy. Recent studies explore paracrine interactions in engineered tissues, sex-based proteomic differences in vascular cells, and hypoxia-induced signaling in cardiac fibroblasts. Her scientific contributions include advancements in 3D bioprinting, microfluidic platforms for disease modeling, and synthetic biology tools for cellular control. McCain’s lab collaborates widely to translate findings into clinical applications, such as personalized medicine and regenerative therapies.

Claire AcevedoView profile

Assistant Professor

• Biomechanics
• Fracture Mechanics
• Skeletal Tissues
• +5 more

Claire Acevedo is an Assistant Professor in the Department of Mechanical and Aerospace Engineering at the University of California San Diego (UCSD), affiliated with the Jacobs School of Engineering. Her lab, the Fracture and Fatigue of Skeletal Tissues Laboratory (F² Lab), focuses on understanding mechanisms of deformation, fracture, and biological responses in skeletal tissues and biomaterials across molecular to macro scales. She holds a Ph.D. from the Swiss Federal Institute of Technology Lausanne (EPFL) and completed postdoctoral research at UC San Francisco and UC Berkeley/Lawrence Berkeley National Laboratory. Dr. Acevedo’s research is funded by the National Science Foundation (NSF), National Institutes of Health (NIH), and the Advanced Light Source. Her work bridges biomechanics, materials science, and high-energy X-ray physics to address bone fragility in aging and diabetes. Key projects include investigating collagen cross-linking effects on bone mechanics and developing novel imaging techniques like deep learning-enhanced synchrotron micro-CT. Education: Ph.D., Swiss Federal Institute of Technology Lausanne (EPFL) Postdoctoral Research: UC San Francisco & UC Berkeley/Lawrence Berkeley National Lab Previous Faculty Position: University of Utah (Mechanical Engineering) Recent contributions include the NSF CAREER Award for studying fracture mechanisms in fragile bones and an NIH R21 grant to explore collagen-level diabetes impacts. Her lab collaborates with the University of Utah Tanner Dance Program to develop K-12 educational initiatives linking dance with biomechanics. Publications span topics like synchrotron imaging innovations, diabetes-induced bone fragility, and collagen nanomechanics. Students in her lab have contributed to advancements in fatigue testing, cross-link analysis, and imaging algorithms. Awards: NSF CAREER Award (2024) NIH R21 Grant (2023) Alice L. Jee Award (2022) Nikon Small World Image of Distinction (2024) The F² Lab hosts a dynamic team with ongoing projects on glycemic effects, synchrotron techniques, and biomaterial design. Future work emphasizes translating findings into clinical fracture prevention strategies and educational outreach.

Carlos MolinaView profile

Professor

• Cancer Research
• Biology of Reproduction
• Molecular Biology
• +4 more

Dr. Carlos Molina is a Professor of Molecular Biology at Montclair State University’s College of Sciences and Mathematics. Previously, he served as an Assistant Professor at Rutgers Medical School’s Department of Obstetrics, Gynecology, and Women’s Health (1994–2006). He holds a B.S. in Biology from the University of Puerto Rico, M.S. and Ph.D. in Biochemistry from Purdue University, and postdoctoral training at the University of Louis Pasteur (France). His research focuses on cancer mechanisms involving tumor suppression proteins in skin cancer cells and ovarian-specific transgenic zebrafish models for ovulation studies. These efforts aim to develop therapeutic agents and reproductive technologies. Dr. Molina has secured grants from the National Institutes of Health, National Science Foundation, and American Association of Cancer Research. He served on NIH study sections for Heart/Lung/Blood Institute and Defense Department Ovarian/Prostate Cancer initiatives. Office hours are consistently held Tuesdays and Thursdays 3:30–5:00 PM via Zoom.

Felix SchweizerView profile

Professor

• Neurobiology
• Synaptic transmission
• Neurotransmitter release
• +5 more

Felix Schweizer is Professor of Neurobiology at the David Geffen School of Medicine, University of California, Los Angeles, and concurrently serves as Interim Director of the Brain Research Institute and Chair of the Graduate Interdepartmental Program for Neuroscience, reflecting his leadership in both research and graduate training. Education Ph.D. in Biochemistry (summa cum laude), University of Basel, 1989 Research Interests Schweizer’s laboratory focuses on the molecular mechanisms of synaptic transmission and neuronal communication. Using electrophysiology, optical imaging, and quantitative proteomics, his group investigates how protein ubiquitination dynamically regulates neurotransmitter release and neuronal excitability. Recent projects explore microbial metabolite sensing by vagal afferents, the synaptic impact of environmental toxicants linked to Parkinson’s disease, and how gravitational load alters vestibular synaptic architecture. Collaborations with Drs. James Wohlschlegel (multiplexed SILAC proteomics), David Krantz (pesticide neurotoxicology), and Larry Hoffman (vestibular biology in altered gravity) extend the lab’s reach from molecular mechanisms to systems-level neuroscience. Scientific Awards No specific awards are listed in the provided text. Advising & Grants As Chair of the Graduate Interdepartmental Program for Neuroscience, Schweizer oversees interdisciplinary Ph.D. training across UCLA. The laboratory continuously hosts post-doctoral fellows and graduate students, and recent funding supports work on ubiquitin-mediated synaptic modulation, pesticide-induced neurodegeneration, and spaceflight-induced synaptic plasticity in the vestibular system. Labs & Teams The Schweizer laboratory, located in the Center for Health Sciences at UCLA, integrates electrophysiology, advanced imaging (serial EM and EM tomography), and biochemical approaches to dissect synaptic function across rodent, Drosophila, and human tissue models.

• Biochemistry and Cell Biology
• Biological Physics
• Regenerative Medicine
• +6 more

Srinjan Basu is a Lecturer in Cell and Developmental Biology at the Department of Life Sciences, Imperial College London. His research focuses on single-molecule and single-cell approaches to study cellular differentiation during mammalian embryo development and related dysregulation in diseases like cancer and epilepsy. He is affiliated with the Faculty of Natural Sciences and maintains a lab at the South Kensington Campus. Education: BA/MSci in Natural Sciences (Biology, Chemistry, Physics) at University of Cambridge (2002–2006) PhD in Molecular, Cellular and Chemical Biology from Harvard University (2006–2012) Research Interests: Technology Development: Single-molecule imaging of nuclear proteins and chromatin dynamics Basic Biology: Pluripotent stem cell differentiation and embryo development Disease Insights: Linking chromatin folding and genome 3D structure to developmental disorders Professional Journey: Postdoctoral work at Harvard developing single-cell Hi-C and live-cell imaging techniques Lab establishment at University of Cambridge before relocating to Imperial College London His lab integrates advanced imaging and sequencing technologies to explore how molecular interactions govern cell fate decisions and their failure in disease contexts.

Jordan CragoView profile

Assistant Professor

• Aquatic Toxicology
• Environmental Toxicology
• Ecotoxicology
• +5 more

Dr. Jordan Crago is an Assistant Professor in the Department of Environmental Toxicology at Texas Tech University and affiliated with the STEM CORE program. His research specializes in aquatic toxicology, investigating how environmental chemicals impact development and reproductive success in fish and invertebrates through integrated field-laboratory approaches. Education: Ph.D. in Biological Sciences, University of Wisconsin, Milwaukee Bachelor of Science, Ohio University Dr. Crago's research employs field observations to guide laboratory experiments focused on adverse outcome pathways across diverse contaminants. His work spans pesticides, microplastics, perfluorinated compounds, and emerging pollutants, emphasizing multi-pathway effects on development and reproduction. He prioritizes identifying high-risk environmental chemicals through mechanistic studies using model organisms like zebrafish and fathead minnow. Analysis of his 2019-2025 publications reveals consistent focus on molecular, physiological, and behavioral endpoints in aquatic toxicology. Key themes include developmental/reproductive toxicity, transgenerational effects, and advanced methodologies like predictive molecular signatures and benchmark dose modeling. His work frequently addresses pesticide impacts, microplastic fate in food webs, and PFAS alternatives using zebrafish as a primary model system. Dr. Crago actively mentors undergraduate researchers, integrating them into data collection, analysis, and publication. Three mentees have co-authored peer-reviewed publications and conference presentations. He contributes to STEM education through Texas Tech's STEM CORE program and volunteers with Lubbock's Boys and Girls Club for after-school programs.

Paul ReynoldsView profile

Lecturer

• Pathology
• Tumour Microenvironment
• Immuno-oncology
• +5 more

Dr. Paul Reynolds is a Lecturer in the Cellular Medicine Division within the School of Medicine at the University of St Andrews. He is affiliated with the Sir James Mackenzie Institute for Early Diagnosis, Centre for Biophotonics, and Biomedical Sciences Research Complex. His research focuses on systems pathology and cancer, with particular emphasis on molecular changes driving disease processes. Dr. Reynolds' research interests span two primary areas: stromal factors in cancer resistance and factors in placental invasion. His work explores how the tumor microenvironment influences cancer progression and therapy resistance, with specific focus on a novel type I membrane protein expressed on stromal fibroblasts. He also investigates similar invasion mechanisms in placental development, examining how trophoblast cells interact with maternal immune cells during pregnancy. His research employs biochemistry, molecular biology, and cell biology approaches to understand disease mechanisms. His publication record shows strong focus on kidney disease mechanisms, particularly podocyte function in health and disease, as well as cancer resistance mechanisms in renal cell carcinoma. Recent work has utilized CRISPR/Cas9 screening approaches to identify factors modulating drug sensitivity. His research demonstrates interdisciplinary connections between cancer biology and reproductive biology through shared invasion mechanisms. Dr. Reynolds actively supervises postgraduate research students, with several thesis projects completed under his supervision. He serves as an external examiner for PhD students at the University of Dundee and holds editorial positions with journals including Frontiers in Physiology and Cancers. His work contributes to UN Sustainable Development Goals related to health and wellbeing, particularly through research on cancer diagnostics and treatment resistance. Dr. Reynolds maintains active research collaborations as evidenced by his extensive publication record and research projects funded by organizations including the Wellcome Trust.

Mandi de MestreView profile

Professor

• Reproductive Biology
• Placental Development
• Equine Medicine
• +5 more

Dr. Mandi de Mestre is a Professor in the Department of Biomedical Sciences at Cornell University's College of Veterinary Medicine. As Director of the Baker Institute for Animal Health and holder of the Dorothy Havemeyer McConville Professorship of Equine Medicine, her research focuses on equine pregnancy biology, placental development, and fetal health. Director, Baker Institute for Animal Health Dorothy Havemeyer McConville Professor of Equine Medicine Affiliated with Cornell's College of Veterinary Medicine Her laboratory investigates: Molecular mechanisms of placental development Genetic causes of early pregnancy loss Congenital musculoskeletal disorders in Thoroughbreds Non-invasive diagnostics for fetal health Comparative studies linking equine and human pregnancy pathologies Recent research trends show strong emphasis on genomic stability, immune interactions during implantation, and epidemiological factors affecting equine pregnancies. Collaborations with institutions like the University of Nottingham and Royal Veterinary College UK highlight her interdisciplinary approach. The Equine Pregnancy Laboratory employs molecular biology, immunology, and genetics to address critical gaps in placental biology, with implications for both veterinary and human medicine.

Jun WuView profile

Assistant Professor

• Stem Cell Biology
• Genome Editing
• Interspecies Chimeras
• +6 more

Dr. Jun Wu is an Assistant Professor in the Department of Molecular Biology at UT Southwestern Medical Center. He holds a PhD in Life Science from the University of Tennessee and completed postdoctoral training at the University of Southern California and the Salk Institute. His research focuses on stem cell biology, genome editing, and interspecies chimeras to advance regenerative medicine and developmental biology. Education: Bachelor of Medicine, Shandong University School of Medicine (China) PhD in Life Science, University of Tennessee (2013) Postdoctoral Fellowships: USC (2013-2015) and Salk Institute (2015-2017) Research Interests: Generation of pluripotent stem cells with distinct molecular/phenotypic features Development of interspecies blastocyst complementation systems Modeling peri-implantation human development using stem cell embryo models Study of species-specific developmental barriers and evolutionary biology Application of chimeras to study cancer resistance and organ size determination Lab Activities: The Wu Lab develops stem cell models to study mammalian development and create regenerative therapies. Key projects include: Creation of interspecies chimeras (human-monkey, rat-mouse) Development of blastoids and peri-gastruloids Analysis of species-specific cell competition mechanisms Engineering cross-species organogenesis systems Grant Activities: Focuses on NIH-funded projects related to stem cell biology, interspecies chimerism, and regenerative medicine applications. Collaborates with institutions like Salk Institute and University of California campuses. Lab Team: Includes postdoctoral researchers like Dr. Yi Ding and a multidisciplinary team of molecular biologists, bioengineers, and computational biologists.