Find Academic Supervisors

Alexander J. VarshavskyView profile

Professor

• Biochemistry
• Genetics
• Molecular Biology
• +7 more

Alexander J. Varshavsky is a Russian-American biochemist and geneticist currently serving as the Thomas Hunt Morgan Professor of Biology at the California Institute of Technology (Caltech), where he has been since 1992. Previously, he was a faculty member at the Massachusetts Institute of Technology (MIT) from 1977 to 1991. His pioneering work on the ubiquitin system and N-degron pathways has transformed understanding of regulated protein degradation. B.S., Moscow University (1970) Ph.D., Institute of Molecular Biology, Moscow (1973) Varshavsky's research spans Biochemistry, Genetics, and Molecular Biology , focusing on: protein degradation signals (degrons), ubiquitin-mediated regulation of DNA repair and transcription, split-ubiquitin protein interaction methods, and the fragment generation (FG) hypothesis for sleep causation. His work has led to major advances in cancer therapy strategies targeting genomic deletions and understanding protein fragment accumulation during wakefulness. Key discoveries include: the first degrons (1986), ubiquitin fusion technique (1986), chromatin immunoprecipitation (ChIP) (1988), and split-ubiquitin method (1994). These innovations enabled breakthroughs in proteomics, including the development of split-protein sensors like split-GFP and split-Cas9 . Major scientific awards include: Albert Lasker Award (2000), Wolf Prize in Medicine (2001), Breakthrough Prize in Life Sciences (2014), and the Dr. Paul Janssen Award (2024). He holds memberships in elite societies including the U.S. National Academy of Sciences (since 1995) and European Molecular Biology Organization (2001). His laboratory's work has profoundly impacted biomedical research, revealing fundamental mechanisms in protein homeostasis, demonstrating ubiquitin's role in DNA replication and repair, and developing genetic tools that remain cornerstones of molecular biology. Current research continues to explore the Arg/N-degron pathway and its implications across fields from cancer biology to plant physiology.

Julia KardonView profile

Assistant Professor

• Mitochondrial Protein Regulation
• Heme Biosynthesis
• AAA+ Protein Unfoldases
• +3 more

Julia Kardon is an Assistant Professor of Biochemistry at Brandeis University . Her research focuses on the molecular mechanisms governing mitochondrial protein activity, quality control, and proteome adaptation to cellular demands. Research Areas: Mitochondrial protein regulation, heme biosynthesis, AAA+ unfoldases, lysosomal degradation, proteomics, and stress response. Education: Ph.D. from the University of California, San Francisco; B.S. from Yale University. Her work investigates how mitochondrial chaperones like ClpX interpret substrate signals to determine outcomes ranging from activation to degradation. Recent studies highlight ClpX's role in heme biosynthesis regulation and disease pathogenesis. Scientific awards include: National Science Foundation Pre-doctoral Fellowship (2004-2007) Ruth L. Kirschstein Postdoctoral Fellowship (NIDDK), NIH (2012-2015) Her publications span microbiology, structural biology, and cell biology, revealing insights into protein degradation mechanisms and mitochondrial-cytoplasmic interactions.

Anup MalaniView profile

Professor

• Law and Economics
• Health Economics
• Development Economics
• +9 more

Anup Malani is the Lee and Brena Freeman Professor at the University of Chicago Law School and a Professor at the Pritzker School of Medicine. He also holds significant affiliations as a University Scholar at Resources for the Future in Washington, a Research Associate at the National Bureau of Economic Research in Boston, and a Senior Fellow at the Schaeffer Center at the University of Southern California. Malani co-founded and serves as Faculty Director of the International Innovation Corps, a social service program sending University of Chicago and foreign university graduates to work on development projects in India and Brazil. Malani earned his PhD in economics and JD, both from the University of Chicago. He clerked for Judge Stephen Williams on the US Court of Appeals for the District of Columbia Circuit and Justice Sandra Day O'Connor on the US Supreme Court. His academic journey includes previous appointments at Harvard Law School as Roscoe Pound Visiting Professor and at the University of Virginia Law School as Associate Professor. Malani's research spans law and economics, health economics, and development economics. His law and economics work focuses on judicial behavior, empirical analysis of legal reforms, and blockchain. His health economics research examines infectious disease control, medical innovation value, health insurance, placebo effects, and medical conflicts of interest. His development economics work concentrates on healthcare supply and financing in India and urban slum quality of life. He leads major research initiatives including the Indian Health Insurance Experiment (an 11,000 household RCT) and impact evaluations of Mission Kakatiya in Telangana, India. Malani's research has been published in leading journals across multiple disciplines including Proceedings of the National Academy of Sciences, Journal of Political Economy, Harvard Law Review, and Nature Medicine. His recent work has focused significantly on COVID-19 pandemic analysis, particularly in Indian contexts, examining infection rates, mortality, and policy responses. Member, American Academy of Arts and Sciences (2021) Emergent Ventures Prize (twice in 2020 for serological work and epidemiological modeling) Order of the Coif (2000) John M. Olin Fellowship in Law and Economics (1998-2000) Bradley Foundation Fellowship (1997-2000) Malani advises governments in India and Indonesia on COVID policy with support from the Asian Development Bank and has advised the World Bank on COVID in South Asia. He serves on University of Virginia's working group planning a National COVID Commission. His teaching spans corporate law, health law, food and drug law, law and economics, and development in the Law School, plus economics and public policy courses across the university. He has supervised numerous research projects and has been principal investigator on multiple large-scale studies examining healthcare and development in India. Malani directs the International Innovation Corps, which partners with government officials in India and Brazil on innovative development projects. He previously served as Faculty Director of the Tata Centre for Development at the University of Chicago. His work bridges academic research with practical policy implementation through collaborations with government agencies, international organizations, and development institutions.

Oliver MühlemannView profile

Professor

• RNA Biology
• Post-transcriptional Gene Regulation
• mRNA Quality Control
• +3 more

Oliver Mühlemann is a Full Professor of Biochemistry at the Department of Chemistry, Biochemistry and Pharmacy, University of Bern, since 2010. He leads a research group focused on post-transcriptional gene regulation, particularly the molecular mechanisms and biological implications of nonsense-mediated mRNA decay (NMD). As Director of the NCCR RNA & Disease since 2014, he bridges fundamental RNA biology with clinical relevance. Education: Biology (University of Bern, 1987-1992), Ph.D. in Cell and Molecular Biology (Karolinska Institute/Uppsala University, 1992-1998) His research explores NMD as a dual-function process: a quality control mechanism degrading aberrant mRNAs and a regulator of physiological mRNA levels. Recent work includes coronavirus interactions with host translation machinery, ribosome quality control pathways, and hnRNP particle dynamics. His group pioneered methods like dual centrifugation for translation-competent lysates and tethered function assays for RNA-binding protein analysis. Selected publications highlight NMD in cancer, coronavirus translational shutdown, and ribosome surveillance. Research spans RNA biology, molecular mechanisms, and therapeutic applications in genetic diseases and virology. Collaborations include structural biology and pharmacological studies. Scientific Awards: Cloëtta Foundation Research Fellowship (2005-2009), ERC Starting Grant (2007) His lab contributes to RNA society and Swiss Society for Molecular and Cellular Biosciences. Current projects involve RNA therapeutics, telomere maintenance, and tuberculosis RNA decay inhibition. Media highlights include discoveries about coronavirus hijacking cell mechanisms and comprehensive mRNA degradation catalogs.

Aurélie LabarreView profile

Research Fellow

• Oceanography
• Microbial Ecology
• Biogeochemistry
• +4 more

Aurélie Labarre is a Postdoctoral Fellow at the Department of Biology , Université Laval, focusing on microbial ecology and oceanography within the CFREF Sentinel North project "Last Ice Microbiomes and Arctic Ecosystem Health" . Her work integrates metagenomics and ecological network analysis to study Arctic microbial communities under climate change. Education : Ph.D. in Marine Sciences/Bioinformatics (2020, UPC), M.Sc. in Microbiology/Genomics (2015, Université Laval), B.Sc. in Microbiology (2013, Université Laval) Her research explores biogeochemical cycles (Nitrogen, Carbon, Sulfur), microbial connectivity in ice-covered seas, and the impact of light-driven photosynthesis shifts on nutrient utilization. Recent publications highlight evolutionary diversification of marine predators, phagocytosis mechanisms, and comparative genomics of uncultured microorganisms. Key awards include the H2020 Marie Sklodowska-Curie Actions SINGEK fellowship (2016). Collaborative efforts span institutions like Arizona State University, University of Oslo, and University of Exeter.

Brian TheyelView profile

Assistant Professor

• cellular neuroscience
• Neural circuits
• neuromodulation
• +5 more

Brian Theyel, M.D., Ph.D. is an Assistant Professor of Psychiatry and Human Behavior at Brown University's Warren Alpert Medical School. His primary academic appointment is in the Department of Psychiatry and Human Behavior, where he conducts research on the cellular mechanisms underlying neuropsychiatric disorders and provides clinical services in the psychiatric emergency room at Butler Hospital. Dr. Theyel earned both his MD and PhD from the University of Chicago in 2012, completing a rigorous dual-degree program that prepared him for his career as a physician-scientist. His educational background reflects a strong foundation in both clinical medicine and basic neuroscience research. Dr. Theyel's research centers on understanding how unique properties of interneurons relate to neuropsychiatric disease, with a particular focus on how inhibitory interneurons regulate brain activity. His laboratory employs advanced techniques including whole-cell patch-clamp recording, local field potential measurements, in vitro neuroimaging, cell-specific gene knockout strategies, and sophisticated neuroanatomical methods. His most significant discovery involves how a specific inhibitory interneuron puts 'the brakes' on brain activity by firing repeatedly in the 'backward' direction during periods of elevated neural activity. Analysis of Dr. Theyel's publication record reveals a consistent focus on neural circuit mechanisms, particularly examining ectopic action potentials in interneurons and their implications for neuropsychiatric disorders. His work bridges basic neuroscience with clinical psychiatry, exploring how cellular and microcircuit dysfunctions contribute to conditions like epilepsy and other neurological disorders. Recent publications show an increasing emphasis on neurodevelopmental disorders and the application of circuit-based approaches to understanding psychiatric disease. Brown University General Psychiatry Residency Education Committee Award (2021) Excellence in Triple Board Training Award - Brown University (2021) Psychiatry Research Mentoring Award – Brown University (2019) Martin Keller Outstanding Resident Award (2016) Chief Resident, Brown University Psychiatry Residency Training Program (2015-2016) Brown Mind-Brain Research day Poster award – 2nd place among residents/fellows (2015) NIMH Outstanding Resident Award (ORAP) (2014) Dr. Theyel is actively involved in teaching and mentoring, supervising residents in the Residency Continuity Clinic and teaching courses including a longitudinal seminar series on 'Evidence-Based Medicine' for psychiatry residents. He co-directs the Brain & Behavior course for first-year medical students at Brown. His research is supported by multiple prestigious funding sources including the Brown Department of Psychiatry and Human Behavior, NINDS, the Norman Prince Neurosciences Institute, the Carney Foundation, and the Simons Foundation. His collaborative network includes prominent researchers in neuroscience, particularly Barry Connors with whom he has published multiple papers. Dr. Theyel maintains an active laboratory dedicated to determining the underpinnings of neuropsychiatric disease at the cellular and microcircuit levels, with the goal of uncovering potential novel treatment targets. His work bridges the gap between basic neuroscience and clinical psychiatry, making significant contributions to understanding how neural circuit dysfunctions contribute to psychiatric disorders.

Aoife MorrinView profile

Associate Professor

• Biochemical Sensor Development
• Wearable Sensors
• Electrochemical Sensing
• +5 more

Dr. Aoife Morrin is an Associate Professor at the School of Chemical Sciences, Dublin City University (DCU), and Director of the National Centre for Sensor Research (NCSR) at DCU. She leads the 'Sample & Sense' research strand within the Insight Centre for Data Analytics, focusing on biochemical sensor platform development. Her work integrates electrochemical and optical transduction mechanisms with soft responsive materials to create wearable sensors for skin surface applications. She has published over 60 peer-reviewed papers (H-index 29, 4000+ citations), edited a book, and contributed to three book chapters. Dr. Morrin’s research spans wearable sensor formats, skin volatile emission profiling for disease biomarker discovery, and educational technology innovations in chemical education. Her recent publications highlight advancements in mobile phone-based sensors, volatilomic analysis of infections, and green chemistry approaches to sensor fabrication. She actively explores the intersection of analytical chemistry, biomedical diagnostics, and environmental monitoring through printed electronics and flexible sensor platforms. Her work also addresses the integration of digital tools like virtual laboratories and micro-skill badging for chemical sciences education. Dr. Morrin collaborates across disciplines to develop non-invasive diagnostic technologies, including for diabetic foot ulcer infections and skin pH monitoring. She contributes to environmental sensor development for pollutants like PFAS and cooking oil VOCs, as well as emerging applications in honey characterization and aging research via skin volatiles.

Marianne Nissen LundView profile

Professor

• Protein oxidation
• Maillard reactions
• Polyphenol-protein interactions
• +6 more

Marianne Nissen Lund is a Professor of Food Chemistry at the Department of Food Science, University of Copenhagen, where she leads the Food Proteins Research Group within the Faculty of Health and Medical Sciences. She has been affiliated with the university since 2004, with a brief industrial postdoc at Novozymes (2011-2013). Appointed as associate professor in 2012, she received a joint appointment with the Department of Biomedical Sciences in 2015 to bridge food and health sciences, and was promoted to Professor of Food Chemistry in 2019. Since 2022, she has been part of the leadership of UCPH Forward, the university's talent management program. Her educational background includes an MSc in Food Science and Technology (cand. techn. al.) from The Royal Veterinary and Agricultural University (KVL) with a focus on food chemistry, followed by a PhD awarded in December 2007. Professor Lund's research focuses on understanding the chemical mechanisms that impact food quality and stability, with primary expertise in protein oxidation, Maillard reactions, and polyphenol-protein interactions. The Food Proteins Group employs a cross-disciplinary approach combining advanced analytical chemistry, biochemistry techniques, and data science to address fundamental challenges in food science. Their work aims to develop sustainable and healthy food designs by understanding chemical interactions between food components during production and storage. Of particular interest is the inhibition and control of protein modifications that cause deterioration of food quality and may induce inflammatory responses. Her recent publications (2022-2025) demonstrate a strong emphasis on protein modifications in food systems, particularly examining how processing affects protein structure and functionality. There is significant focus on infant nutrition, plant-based alternatives, and the development of analytical methods to quantify protein modifications. Her work effectively bridges fundamental food chemistry with practical applications in food design, nutrition, and health. Among her scientific recognitions, she was awarded the IMS International Prize for Meat Science and Technology in 2007, which received considerable media attention with coverage by 58 news outlets, blog posts, and social media mentions. Professor Lund leads multiple major research initiatives including the SEEDFOOD project (2022-2027, Novo Nordisk Foundation) focused on plant seed proteins for sustainable foods, the INFANT-I project (2018-2022) on infant formula development, the INSITUQUANT project (2018-2022) on protein modification quantification, and the ICOM project (2018-2023) on controlling Maillard reactions in dairy. She maintains strong industry collaborations with partners like Arla Foods and academic institutions worldwide. The Food Proteins Research Group operates state-of-the-art facilities including (Ultra) High Performance Liquid Chromatography equipment, Liquid Chromatography Tandem Mass Spectrometry, various spectroscopy systems, and specialized equipment for food analysis. The group follows a hypothetico-deductive approach to experimental design and works closely with the food industry to translate fundamental knowledge into practical applications for sustainable food production.

Alexander KellerView profile

Professor

• Ecology
• Biodiversity
• Bioinformatics
• +5 more

Prof. Dr. Alexander Keller is a Professor at Ludwig Maximilian University of Munich (LMU), based at the LMU Biocenter in Planegg-Martinsried, Germany. He leads the "Cellular and Organismic Networks" research group within the Graduate School Life Science Munich (LSM), integrating field ecology, bioinformatics, and next-generation sequencing technologies to study ecological networks. His research centers on biodiversity dynamics within the plant-microbe-pollinator triangle , examining mutualistic interactions, microbiome compositions, and genomic-level molecular processes. Key methodologies include DNA metabarcoding, phylogenetic reconstructions, and computational workflow development. His work addresses ecosystem resilience, biodiversity loss, and conservation strategies under environmental change, with emphasis on land-use impacts, urbanization, and climate gradients across tropical and temperate ecosystems. Recent publications (2025) demonstrate strong trends in pollination ecology, microbiome analysis, and biodiversity monitoring using advanced sequencing . His studies reveal how landscape heterogeneity affects bee-pollen networks, how host identity shapes microbiomes, and how urban bees adapt foraging strategies. Notable methodological contributions include the LEPY pipeline for morphological analysis and MetAnoDe for metabarcoding quality control, alongside extensive work on tropical forest regeneration and undescribed species cataloging. Scientific Awards: No awards were mentioned in the provided text. Information regarding student advising and research grants was not provided in the available text. The "Cellular and Organismic Networks" group develops open computational pipelines and laboratory protocols for ecological data analysis. They conduct fieldwork across Ecuadorian rainforests, European grasslands, and urban environments, maintaining databases for trait analysis and sequence curation while adhering to open science principles. Current projects investigate microbiome transmission in bee-flower networks, forest succession dynamics, and the molecular basis of ecological resilience under global change.

Hongyu ZhaoView profile

Professor

• Biostatistics
• Computational Biology
• Genetics
• +9 more

Dr. Hongyu Zhao is the Ira V. Hiscock Professor of Biostatistics and Professor of Genetics and Statistics & Data Science at Yale University. He leads interdisciplinary research at the intersection of statistics, genomics, and public health, with formal training from Peking University (BS, 1990) and University of California-Berkeley (PhD, 1995). Yale School of Public Health Yale Department of Biostatistics Yale Cancer Center Yale Center for Genomic Health Women's Health Research at Yale Connecticut Academy of Science & Engineering His research focuses on statistical method development for genomics data analysis, including genome-wide association studies , single-cell RNAseq , network modeling , and genetic risk prediction . He applies these methods to major disease areas like cancer , PTSD , neuroscience , and precision medicine . His recent publications demonstrate methodological advances in spatial transcriptomics and foundation models for multi-omics integration. He has received multiple honors including the Mortimer Spiegelman Award and Pao-Lu Hsu Award , with fellowship in AAAS, ASA, and IMS. Dr. Zhao has trained over 110 doctoral and postdoctoral researchers, many of whom hold tenured positions at leading institutions. His lab develops open-source software and contributes to major consortia like the Million Veteran Program and Connecticut Academy of Science & Engineering .

• Comparative Pathology
• Veterinary Pathology
• Translational Research
• +13 more

Carmen Jane Booth, DVM, PhD, is an Associate Professor on Term in the Department of Comparative Medicine at Yale School of Medicine. She serves as the Director of the Comparative Pathology Research Core, where she provides diagnostic pathology services and fosters collaborative research involving rodent and other animal models. Her work bridges veterinary medicine, translational pathology, and biomedical research across Yale and external institutions. Education: PhD in Pathology, University of Washington, Seattle (2005) Postdoctoral Fellow, University of Washington (2003) Postdoctoral Fellow, Harvard Medical School, New England Primate Research Center (1998) DVM, University of California at Davis, School of Veterinary Medicine (1992) BS in Animal Science Pre-Vet, University of California at Davis (1987) Non-Degree Program, Animal Science Pre-Vet, California State Polytechnic University (1984) Her research focuses on comparative and translational pathology , particularly in mouse and canine models. Key areas include the genetics and physiology of polyhydroallantois in dogs, mechanisms of uterine fibroid development in humans and primates, and the use of the WAG/RijYcb rat model for hemophilia A. She also contributes to studies on Lyme disease, NASH fibrosis, and metabolic influences on infection and immunity. Her collaborative projects involve interdisciplinary teams across immunology, oncology, and infectious diseases. Recent publications highlight her involvement in chronic disease mechanisms , including persistent Borrelia peptidoglycan, adiponectin’s role in tick-borne pathogen acquisition, hepatocyte-driven fibrosis in NASH, and the impact of ketogenic diets on viral infections in aging. These works reflect a strong trend in translational immunometabolism, fibrotic diseases, and host-pathogen interactions . Scientific Contributions: Active peer reviewer for journals including Journal of the American Association for Laboratory Animal Science , Veterinary Pathology , and Molecular Cancer Therapeutics . Frequent collaborator with leading Yale researchers such as Erol Fikrig, Akiko Iwasaki, Andrew Wang, and Carlos Fernandez-Hernando. Dr. Booth mentors postdoctoral fellows and graduate students, and teaches rodent necropsy and blood collection techniques. She plays a vital role in supporting Yale’s research infrastructure through her leadership in the Comparative Pathology Research Core, enabling high-quality animal model studies across diverse scientific domains.

• Computer Science
• Telecommunications Engineering
• Mobile and Wireless Networks
• +3 more

Dr Shahedur Rahman is a Senior Lecturer in Computer Science at Middlesex University , with extensive contributions to telecommunications engineering, image processing, and bioinformatics. His research focuses on wireless network optimization, perceptual distortion metrics for video coding, and molecular biology database integration. Research Interests : Interference management in LTE/5G networks Perceptual quality assessment in multimedia systems Computer vision for accessibility and mobility aids Integration of biological and medical databases Wavelet-based image compression Genomic data analysis Selected Scientific Publications highlight trends in: Dynamic channel allocation techniques for LTE networks SSIM/SATD hybrid distortion metrics Gene mutation data modeling Image processing for visual impairment assistance Database interoperability in medical systems Optimization algorithms for hardware systems

Michael P. GustafsonView profile

Associate Professor

• Cellular Immunotherapy
• Human Immunology
• Cancer Immunotherapy
• +7 more

Michael P. Gustafson, Ph.D., is an Associate Professor in the Department of Laboratory Medicine and Pathology and Department of Immunology at Mayo Clinic, where he also serves as Scientific Director of the Nyberg Human Cellular Therapy Laboratory in Phoenix, Arizona. He holds leadership roles including Associate Chair of Research and is deeply involved in translational research and clinical trial development. Ph.D. in Molecular Biology, Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic College of Medicine Postdoctoral Research Fellowship, Fred Hutchinson Cancer Research Center B.S. in Biology, North Park College Dr. Gustafson's research focuses on cellular immunotherapies , including CAR-T cells, natural killer cells, and dendritic cell vaccines for cancer and autoimmune diseases. He investigates systemic immunity in humans , how cancer alters immune function, and how physical activity can enhance immunotherapy responses. His work also emphasizes biomarker development to assess cell product quality and patient response. His recent publications highlight a strong trajectory in immunotherapy safety , exercise immunology , solid tumor CAR-T engineering , and immune monitoring . Themes include improving therapeutic specificity, understanding secondary malignancy risks, and leveraging lifestyle interventions to boost immune efficacy. Dr. Gustafson has earned recognition through key roles in national organizations: Member, Immuno & Gene Therapy Committee, International Society for Cell and Gene Therapy (2019–present) Chair and Scientific Reviewer, Peer Reviewed Cancer Research Program, Congressionally Directed Medical Research Program (2016–present) Champion, Society for Immunotherapy of Cancer (2013–present) He actively mentors students and collaborators, though specific advisees are not listed. His lab fosters critical partnerships across Mayo Clinic and external institutions to advance cell therapy from bench to bedside. He provides regulatory and quality expertise for IND-enabling studies and early-phase clinical trials. Dr. Gustafson leads the Nyberg Human Cellular Therapy Laboratory , a core facility dedicated to the biomanufacturing, testing, and translational development of cell-based therapeutics. The lab supports both academic and clinical research teams in producing GMP-compliant cellular products for human trials.

Dörte SolleView profile

Researcher

• Bioprocess Analytics
• Cell Cultivation
• Chemometrics
• +6 more

Dr. Dörte Solle is a Researcher at the Institute of Technical Chemistry, Leibniz University Hannover, within the Faculty of Natural Sciences. She leads the Bioprocess Analytics working group and serves as Deputy Representative for Research Staff on the Faculty Council. Her work bridges research, teaching, and technological innovation in bioprocessing. Research Interests: Bioprocess Analytics Cell Cultivation (especially CHO cells for monoclonal antibody production) Chemometrics and multivariate data analysis Bioprocess Automation and control Development of spectroscopic and optical sensors for online monitoring Disposable bioreactor systems and process intensification Her recent publications (2022–2025) highlight a strong trend toward integrating machine learning, digital twins, and advanced sensor systems into bioprocess engineering. There is a consistent focus on improving monoclonal antibody production through quality-by-design, perfusion systems, and real-time analytics. The work combines experimental innovation with modeling for intelligent process control. Scientific Awards: No awards explicitly mentioned in the provided text. Advising and Grants: While specific student names and grant details are not listed, Dr. Solle leads a research group (Solle AG) and co-authors multiple publications with junior researchers, indicating active advising in PhD and postdoctoral training. Her involvement in projects involving 3D-printed devices, sensor development, and process optimization suggests participation in funded research initiatives, likely supported by national or institutional grants. Labs and Teams: Dr. Solle heads the Bioprocess Analytics group at the Institute of Technical Chemistry. The team focuses on developing and applying advanced analytical methods for bioprocess monitoring, including fluorescence spectroscopy, NIR/MIR, in situ microscopy, and novel disposable sensor systems. The lab is equipped for cell cultivation from 15 mL to 50 L scales and emphasizes automation and data-driven process control.

Luke A. GilbertView profile

Assistant Professor

• Functional Genomics
• Epigenetics
• CRISPR Technology
• +7 more

Luke A. Gilbert is an Assistant Professor in the Department of Cellular and Molecular Pharmacology at the University of California, San Francisco (UCSF), School of Medicine. He leads an independent research program focused on functional genomics, epigenetic engineering, and cancer biology, supported by multiple NIH grants including an R01, DP2, and R41 awards. His research centers on developing and applying CRISPR-based technologies to dissect gene regulation, chromatin dynamics, and cancer vulnerabilities. Key areas include epigenetic memory editing using CRISPRoff, combinatorial chromatin perturbations, and identifying regulatory elements in cancer. His work spans glioblastoma, prostate cancer, and acute myeloid leukemia, with a strong emphasis on therapeutic translation. The recent publications reveal a strong trend in high-throughput functional genomics, single-cell and spatial analyses, and integrative multiomics to uncover mechanisms of drug resistance, immune evasion, and oncogenic signaling. His team leverages cutting-edge tools like perturb-seq and engineered CRISPR systems to interrogate complex biological systems in vivo and in vitro. Scientific Awards: Virginia and Daniel K. Ludwig Graduate Research Fellow Leukemia and Lymphoma Society Postdoctoral Fellow NIH/NCI Pathway to Independence Award Gabrielle's Angel Foundation Medical Research Fellow NIH Director's New Innovator Award (2019–2023) Pew-Stewart Scholar for Cancer Research (2020) AAAS / Martin and Rose Wachtel Cancer Research Award (2022–2023) Prostate Cancer Foundation Challenge Award (2022–2027) CRUK/NCI Cancer Grand Challenge Award (2022–2027) NIH NHGRI UM1 HG012660 Luke Gilbert has secured significant grant funding as Principal Investigator on multiple NIH projects, including a DP2 New Innovator Award and R01 grants focused on DNA methylation editing and genetic interaction mapping in the human nucleus. These grants support his lab’s innovative work in functional genomics and cancer biology. He is actively involved in collaborative science, as seen through his participation in large consortia such as the MorPhiC Consortium, and his research is conducted within state-of-the-art facilities at UCSF, leveraging the university’s strengths in biomedical research, genomics, and translational medicine.