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Alexis BattleView profile

Associate Professor

• Genomics
• Machine Learning
• Computational Biology
• +3 more

Alexis Battle is an Associate Professor at Johns Hopkins University with appointments in Biomedical Engineering , Computer Science , and Genetic Medicine (secondary). She directs the Malone Center for Engineering in Healthcare and serves as Deputy Director of the Data Science and AI Institute . Educated at Stanford University (PhD in Computer Science, 2013), Battle transitioned to academia after leadership roles at Google. Research Focus: Battle’s work bridges genomics and machine learning , emphasizing the impact of genetic variation on human health. Her lab develops tools like Watershed to predict functional effects of rare variants, aiming to enhance rare disease diagnosis. Key themes include non-coding DNA analysis , personalized genomics , and systems biology , with applications in cardiovascular disease and neurodegenerative disorders . Publications & Awards: Over 60 peer-reviewed articles in journals like Nature , Science , and Genome Biology , with recent emphasis on single-cell transcriptomics , multiomics integration , and telomere biology . Recipient of the President’s Frontier Award (2022), Microsoft Investigator Fellowship (2019), and Searle Scholar (2016). Scientific Awards: 2022 President’s Frontier Award 2019 Microsoft Investigator Fellowship 2019 Johns Hopkins Discovery Award 2017 Johns Hopkins Catalyst Award 2016 Searle Scholar Advising & Funding: Mentors 11 PhD students, 3 undergraduates, and postdoctoral fellows. Her research is funded by NIH, Searle Scholars, and institutional grants. The Battle Lab collaborates on projects like the GTEx Consortium , focusing on gene regulation and clinical genomics .

Vikramaditya G. YadavView profile

Associate Professor

• Biocatalysis
• Bioremediation
• Bioprocess engineering
• +15 more

Vikramaditya G. Yadav is an Associate Professor at the University of British Columbia (UBC) in the Department of Chemical and Biological Engineering, Faculty of Applied Science. He directs the Master of Engineering Leadership (MEL) Program in Sustainable Process Engineering and leads the BioFoundry research group. Education: B.A.Sc., University of Waterloo (2007) Ph.D., Massachusetts Institute of Technology (2013) Postdoctoral Associate, Harvard University (2014) His research spans sustainable chemical manufacturing, metabolic engineering, and biotechnology. Key areas include: Designing biosynthetic enzymes for biomass valorization Developing bioremediation strategies for industrial water quality Creating innovative drug delivery systems and tissue engineering solutions Advancing synthetic biology for pharmaceutical and bioenergy applications His recent work focuses on ocular drug delivery, cannabinoid biosynthesis in E. coli, lignin-based nanoparticles for cancer therapy, and computational analysis of plant secondary metabolites. Collaborations with start-ups, industry, and medical labs drive innovation in Canada's bioeconomy. Professional Leadership: Chair, Biotechnology Division of the Chemical Institute of Canada Associate Editor, The Canadian Journal of Chemical Engineering He is affiliated with UBC's BioProducts Institute and contributes to project-based learning pedagogy.

Michael McAlpineView profile

Professor

• 3D Printing
• Nanotechnology
• Biomedical Engineering
• +4 more

Michael McAlpine is a Professor in the Mechanical Engineering department at the University of Minnesota . He also holds affiliations with the Biomedical Engineering and Electrical and Computer Engineering departments. His research focuses on 3D printing functional materials & devices , Nanoscale inks , Biomedical devices , Bioelectronics , and Flexible Microsystems . Research Interests : 3D Printing, Biomedical Engineering, Nanotechnology, Flexible Electronics, Microfluidics Labs : ME 361/363 Contact : mcalpine@umn.edu , (612) 626-3303, ME 117 Recent Research Trends include 3D Printed Biomedical Devices , Flexible Electronics , and Bioprinting Applications . His work spans from Spinal Organoid Formation to Programmable Drug Release Capsules . Scientific Award : Circulation Research 2020 Best Manuscript Award

James BriscoeView profile

Professor

• Developmental Biology
• Molecular Signaling
• Transcriptional Networks
• +4 more

James Briscoe is a Senior Group Leader at The Francis Crick Institute in London, where he leads a research group focused on developmental biology and morphogen signaling. He previously held positions at the Medical Research Council's National Institute for Medical Research, which later became part of the Francis Crick Institute. Education: BSc in Microbiology and Virology from the University of Warwick, UK PhD from Imperial Cancer Research Fund/King's College London Postdoctoral training at Columbia University with Thomas Jessell Dr. Briscoe's research focuses on the molecular and cellular mechanisms of graded signaling by morphogens and the role of transcriptional networks in cell fate specification. His laboratory employs a range of experimental and computational techniques using model systems including mouse and chick embryos and embryonic stem cells. His work has significant implications for understanding developmental processes and their relationship to disease. His recent publications demonstrate a continued focus on morphogen gradients, neural tube development, and computational approaches to understanding cell fate decisions. His research increasingly integrates single-cell technologies and computational modeling to unravel the complexities of developmental patterning. Scientific Awards and Honors: EMBO Young Investigator (2001) EMBO Gold Medal (2008) Elected to EMBO (2009) Fellow of the Academy of Medical Sciences (2019) Fellow of the Royal Society (2019) As Editor-in-Chief of the journal Development since 2018, Dr. Briscoe plays a significant role in shaping the field of developmental biology. His leadership extends to mentoring researchers and contributing to scientific policy discussions, as evidenced by his recent publication 'Science under siege: protecting scientific progress in turbulent times.' Dr. Briscoe's laboratory at the Crick Institute is well-equipped with access to advanced facilities including light microscopy, flow cytometry, genomics, and computational resources, enabling a multidisciplinary approach to developmental biology questions.

Thibault MayorView profile

Professor

• Protein Homeostasis
• Ubiquitin Proteasome System
• Neurodegenerative Diseases
• +7 more

Thibault Mayor is a Professor in the Department of Biochemistry and Molecular Biology and the Michael Smith Laboratories at the University of British Columbia (Vancouver). His research focuses on understanding how cells manage misfolded proteins, with implications for neurodegenerative diseases like Parkinson's and Alzheimer's. He holds academic affiliations with the Centre for High-Throughput Biology (CHiBi) and has been recognized with awards including the UBC Killam Teaching Award (2020). Education: BSc, University of Geneva, Switzerland (1997) PhD, University of Geneva & Max Planck Institute of Biochemistry, Germany (2001) Postdoctoral Fellow, California Institute of Technology (2002) Research Interests: Mayor's lab investigates protein homeostasis, ubiquitin-proteasome system dynamics, and the molecular mechanisms underlying protein aggregation in aging and disease. Projects include proteomic approaches to identify aggregation-prone proteins and develop microbial cell factories for protein production. Grants & Awards: CIHR Project Grant ($730K, 2018) Michael Smith Foundation Career Award (2012) UBC Killam Teaching Award (2020) Labs & Collaborations: The Mayor Lab is part of the Michael Smith Laboratories and collaborates with computational biologists like Jörg Gsponer. They maintain active partnerships in proteomics and systems biology, contributing to initiatives like the BC Proteomics Network.

Jeremy DahlView profile

Professor

• Medical Ultrasound Imaging
• Ultrasonic Beamforming
• Image Reconstruction
• +7 more

Jeremy Dahl is a Professor of Radiology (Pediatric Radiology) at Stanford University School of Medicine. He directs the Ultrasound Imaging & Instrumentation Lab and serves as Director of Research Academic Affairs in the Department of Radiology since 2020. He holds multiple affiliations across Stanford including Bio-X, the Cardiovascular Institute, Wu Tsai Human Performance Alliance, Maternal & Child Health Research Institute, Stanford Cancer Institute, and Wu Tsai Neurosciences Institute. Dr. Dahl received his B.S. in Electrical Engineering from the University of Cincinnati (1999) and Ph.D. in Biomedical Engineering from Duke University (2004). His research focuses on developing ultrasonic beamforming and image reconstruction methods for diagnostic imaging applications, particularly techniques that generate high-quality images in difficult-to-image patients. His laboratory specializes in B-mode and Doppler imaging techniques that utilize additional information from ultrasonic wavefields to improve image quality and develop real-time imaging systems for clinical applications including cardiac, liver, and fetal imaging. Dr. Dahl's research has led to significant advancements in ultrasound molecular imaging platforms, sound speed estimation, aberration correction, and reverberation noise suppression. His work often bridges engineering innovation with clinical applications for cancer detection and other diseases. His recent publications demonstrate strong focus on machine learning applications in ultrasound, distributed aberration correction, and molecular imaging techniques. Fellow, American Institute of Ultrasound in Medicine (2021) Senior Member, Institute of Electrical and Electronics Engineers (2020) Distinguished Investigator Award, The Academy for Radiology & Biomedical Imaging Research (2018) Outstanding Paper Award, IEEE Ultrasonics, Ferroelectrics, and Frequency Control Society (2011) Dr. Dahl serves in editorial roles for major journals including IEEE Transactions on Medical Imaging (2017-2024) and IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control (2013-Present). His laboratory has successfully translated numerous innovations into clinical applications, with multiple patents including recent developments in pulsed focused ultrasound therapy and speed of sound quantification.

• Nuclear Magnetic Resonance (NMR)
• In vivo imaging
• MRI pulse sequence development
• +7 more

Professor Guy Williams is a leading academic at the University of Cambridge with a focus on imaging science and clinical neurosciences, affiliated with Downing College and the Wolfson Brain Imaging Centre . Holding a PhD in Physics from his initial Natural Sciences degree, he specializes in nuclear magnetic resonance (NMR) and MRI techniques for brain imaging. Education: BA, PhD in Physics His research centers on non-invasive imaging of brain structure and function, particularly in traumatic brain injury (TBI) and dementia. His work involves developing novel MRI pulse sequences and advanced data analysis algorithms, including AI-based diagnostic tools. He leads studies on white matter integrity post-trauma, longitudinal dementia assessment, and applications of MRI in disorders of consciousness and addiction. Recent publications highlight collaborations in traumatic brain injury outcomes, AI-guided dementia prediction, and neuroimaging of post-COVID cognitive deficits. His team's work on ultra-high field laminar fMRI and distortion correction methods has advanced clinical neuroscience applications. Key techniques include diffusion tensor imaging (DTI), 7 Tesla MRI, and positron emission tomography (PET/MR). His research spans from basic NMR physics to clinical translation, with a strong emphasis on multi-site studies and real-world diagnostic implementation.

Josh AtkinsonView profile

Assistant Professor

• Synthetic Biology
• Protein Engineering
• Electrochemistry
• +7 more

Josh Atkinson is an Assistant Professor in the Department of Civil and Environmental Engineering and the Omenn-Darling Bioengineering Institute at Princeton University. His research focuses on using synthetic biology and protein engineering to control electron transport in microbes for environmental applications, such as bioelectronic sensors and bioremediation. The Atkinson Lab investigates microbial energy processing, biofilm-electronic interfaces, and sustainable biotechnologies. Affiliations: Princeton University, Omenn-Darling Bioengineering Institute Research Interests: Microbial electron transport, bioelectronic systems, environmental monitoring, sustainable catalysis His work bridges disciplines like electrochemistry, bioengineering, and environmental science to engineer living materials for real-world challenges. The lab recruits students across levels, emphasizing diversity and interdisciplinary collaboration. Recent projects include real-time contaminant sensors and light-controlled biofilm patterning. Articles highlight innovations in bioelectronics and microbial systems engineering. The lab’s future directions involve scaling-up bioelectronic devices and enhancing microbial community understanding.

Appala Raju BadireddyView profile

Associate Professor

• Water Quality Engineering
• Membrane Separation Processes
• Environmental Nanotechnology
• +5 more

Dr. Appala Raju Badireddy is an Associate Professor in the Department of Civil and Environmental Engineering at the University of Vermont (UVM), and Director of the Water Treatment & Environmental Nanotechnology (WTEN) Laboratory. He is also co-founder and CTO of Secure Surgical Solutions LLC, and a founding member of Vermont Initiative for Biological and Environmental Surveillance (VIBES). His research focuses on sustainable membrane processes, environmental nanotechnology, nanometrology, and water security. Education: Ph.D., Environmental Engineering, University of Houston (2003-2009) M.Tech., Chemical Engineering, Indian Institute of Technology Madras (2001-2003) B.Tech., Chemical Engineering, Jawaharlal Nehru Technological University Hyderabad (1997-2001) Postdoctoral Research, Duke University (2009-2014) under Prof. Mark Wiesner Research Interests: Sustainable Membrane Processes: Water/wastewater treatment, desalination, anti-fouling strategies, and resource recovery. Environmental Nanotechnology: Nano-enabled sensors, remediation, and implications of nanomaterials in ecosystems. Environmental Chemodynamics: PFAS fate/transport, nutrient cycling, and contaminant toxicity. Water Security: Real-time monitoring systems and soil health assessments. His work integrates lab-scale innovations with field applications, emphasizing interdisciplinary collaboration. Recent Research Trends: Recent publications highlight advancements in PFAS remediation, electric-field enhanced filtration, and living lab approaches to precision agriculture. He explores nanomaterials for water treatment while addressing their environmental implications through novel detection methods like ED-HSI microscopy. Labs & Initiatives: WTEN Lab: Focuses on nanotechnology-driven water solutions. VIBES: Develops environmental surveillance tools for public health. Secure Surgical Solutions: Applies nanotechnology to medical devices.

Joseph P. BresslerView profile

Associate Professor

• Neurotoxicology
• Environmental Health Sciences
• Metal Transporters
• +12 more

Joseph P. Bressler is an Associate Professor at Johns Hopkins University, jointly affiliated with the Bloomberg School of Public Health and the Krieger School of Arts and Sciences. He is a member of the Department of Environmental Health and Engineering and conducts research at the Kennedy Krieger Institute in Baltimore, Maryland. His work bridges public health, neuroscience, and molecular toxicology, focusing on environmental impacts on brain development. Education: PhD, Rutgers University, 1978 Dr. Bressler’s research centers on neurotoxicology, particularly how environmental pollutants such as lead, cadmium, and aluminum disrupt metal transport systems and affect neurodevelopment. His laboratory investigates the role of iron and other metal transporters at the blood-brain barrier and in glial cells, revealing mechanisms of metal uptake and toxicity. His work has implications for understanding autism, fetal alcohol syndrome, and other neurodevelopmental disorders. His recent publications highlight ongoing research into metal homeostasis, cytotoxicity in cancer and neuronal cell lines, e-cigarette aerosol variability, and epigenetic changes in sex chromosome aneuploidies. The research spans molecular mechanisms, in vitro models, and human health outcomes, demonstrating a multidisciplinary approach to environmental health. Scientific Contributions: Elucidated how lead and cadmium hijack iron transporters to enter the brain Demonstrated aluminum activation of iron uptake pathways in glial cells Investigated flavoring agents like ethyl maltol in enhancing metal toxicity Explored epigenetic and behavioral impacts in rare genetic conditions Dr. Bressler has advised numerous researchers and collaborators across disciplines. His work has been supported by federal and institutional grants, though specific funding details are not provided in the source text. He actively publishes in high-impact toxicology and environmental health journals, with research cited in policy and public health discussions. He leads a research laboratory focused on cellular and molecular mechanisms of neurotoxicity, utilizing in vitro models of the blood-brain barrier, astrocytes, and neuronal cell lines. His team collaborates widely across neuroscience, public health, and environmental engineering domains.

Raphael FranziniView profile

Associate Professor

• Drug Discovery
• Medicinal Chemistry
• Bioorthogonal Chemistry
• +3 more

Raphael Franzini serves as Associate Professor of Medicinal Chemistry at the University of Utah, actively contributing to the Biological Chemistry PhD Program. His research pioneers innovative chemical approaches for therapeutic development, with dual focus on DNA-encoded library technologies and bioorthogonal drug delivery systems. His educational foundation includes an M.S. from the Swiss Federal Institute of Technology (Lausanne) and a Ph.D. from Stanford University. This training underpins his group's multidisciplinary methodology combining organic synthesis, bioconjugation, computational modeling, and advanced imaging techniques. Dr. Franzini's research program centers on two transformative areas: First, advancing DNA-encoded library screening through computational integration to identify leads for challenging targets like Tankyrase and Sirtuin 6, with recent work addressing false negatives in machine learning prediction. Second, developing novel bioorthogonal release chemistry using isonitrile-tetrazine reactions for spatiotemporally controlled drug activation, validated in zebrafish models. His group emphasizes both technological innovation and therapeutic translation, with chemistry designed to minimize off-target effects in solid tumors. Analysis of his 15 most recent publications reveals escalating integration of computational methods with experimental library screening, alongside refinement of bioorthogonal release kinetics. The work spans chemical biology, medicinal chemistry, and pharmaceutical sciences, with growing emphasis on machine learning for library data interpretation and in vivo validation of drug-release systems. Dr. Franzini maintains an active research laboratory that provides comprehensive training in cutting-edge drug discovery methodologies. His group culture prioritizes both scientific innovation and researcher development, with projects spanning from fundamental reaction kinetics to therapeutic applications. The lab's infrastructure supports organic synthesis, molecular imaging, and computational analysis for advancing precision therapeutics.

Christian Erik PohlView profile

Adjunct Professor

• Environmental Science
• Sustainability Science
• Transdisciplinary Research
• +3 more

Prof. Dr. Christian Erik Pohl is an Adjunct Professor at ETH Zurich's Department of Environmental Systems Science and Head of the Institute for Environmental Decisions (IED) and the Transdisciplinarity Lab (TdLab). His research focuses on advancing transdisciplinary approaches to address complex environmental and societal challenges, emphasizing sustainable development. He holds a doctorate and habilitation in environmental science from the University of Bern. Key roles include membership in the Swiss National Science Foundation’s NRP 82 steering committee and the scientific advisory board of td-net. His contributions include seminal works like Principles for Designing Transdisciplinary Research and the Handbook of Transdisciplinary Research , fostering global collaboration in sustainability science. Awards include the KITE Award (2020) for teaching excellence and the Swiss-academies award (2015). He co-leads the TdLab, advancing methods for integrating academic and societal knowledge to tackle issues like biodiversity, water management, and climate change. His courses include 'Tackling Environmental Problems' and 'Transdisciplinary Research: Challenges of Interdisciplinarity and Stakeholder Engagement,' reflecting his commitment to education in sustainability science.

Donald RioView profile

Professor

• Nucleic Acid Transactions
• Transposable Elements
• RNA Binding Proteins
• +3 more

Donald Rio holds the Richard and Rhoda Goldman Distinguished Chair in the Biological Sciences and is a Professor of Biochemistry, Biophysics, and Structural Biology. He is affiliated with the Division of Biochemistry and Molecular Biology and the Center for Integrative Genetics. His lab focuses on nucleic acid transactions, including transposable element mobilization (P elements) and RNA binding protein mechanisms controlling alternative splicing. Research highlights include studies on THAP9 proteins in humans/zebrafish, cryo-EM structural analysis of transposase-DNA complexes, and splicing regulation in neurodegenerative diseases like ALS and Parkinson’s. His work combines biochemical, genetic, and computational approaches, including the development of the Junction Usage Model (JUM) for splicing analysis. Research interests span transposition mechanisms linked to HIV integration, immune system recombination, and evolutionary genome dynamics. His team investigates how RNA binding proteins like hnRNPA1 influence splicing in disease contexts, with projects involving CRISPR-based models and patient RNA-seq data analysis. Collaborations include studies on splicing accuracy across tissues and age, and the impact of splicing defects in neurodegenerative disorders. Key awards include the Goldman Chair. His lab’s contributions bridge fundamental molecular mechanisms with translational applications in genetic disease modeling and drug discovery. Recent work focuses on isogenic stem cell models (iSCORE-PD) for Parkinson’s research and structural biology insights into transposase function. Grants and projects involve NIH funding for ALS splicing studies and collaborations with institutions like the Buck Institute. His lab actively publishes in top journals such as Genome Research , PNAS , and Nature , with a strong emphasis on cryo-EM and bioinformatic methods.

John C. DoyleView profile

Professor

• Control Theory
• Dynamical Systems
• Network Science
• +4 more

John C. Doyle is the Jean-Lou Chameau Professor of Control and Dynamical Systems, Electrical Engineering, and BioEngineering at the California Institute of Technology (Caltech), where he holds appointments in the Division of Engineering and Applied Science with primary affiliation in the Control and Dynamical Systems Department. His research bridges theoretical foundations with applications across biological, technological, medical, and ecological networks. He earned a BS and MS in Electrical Engineering from MIT (1977) and a PhD in Mathematics from UC Berkeley (1984), followed by consultancy at Honeywell Systems and Research Center (1976-1990). MIT: BS & MS in Electrical Engineering (1977) UC Berkeley: PhD in Mathematics (1984) Doyle's research centers on universal laws and architectures in complex systems, emphasizing robustness-efficiency tradeoffs, speed-accuracy tradeoffs (SATs), diversity-enabled sweet spots (DeSS), bowtie/hourglass structures, and evolvability. His work pioneers System Level Synthesis (SLS) for control systems with sparse, local, saturating, delayed, noisy, quantized, and distributed (SLSDNQD) components, integrating control theory, computation, communication, and machine learning to address challenges from neural networks to infrastructure resilience. Key concepts include virtualization, horizontal transfer, and virality in multiscale systems. Analysis of his publication trends reveals consistent interdisciplinary impact across neuroscience (brain connectivity modeling), systems biology (metabolic oscillations), network science (internet topology), and physics (turbulence, earthquakes), with recurring themes of robust-efficiency limits and architectural principles governing complex networks. His work demonstrates exceptional translation from abstract theory to practical tools like the Matlab Robust Control Toolbox and Systems Biology Markup Language (SBML). His scientific recognition includes: 1990 IEEE Baker Prize (ranked among top 10 most important mathematics papers 1981-1993) Three IEEE Automatic Control Transactions Awards (1998, 1999, 2021) ACM Sigcomm Paper Prize (2004) and Test of Time Award (2016) IEEE Control Systems Field Award (2004) Multiple early-career honors including IEEE Centennial Outstanding Young Engineer (1984) Doyle has mentored generations of students whose contributions include foundational software tools adopted globally. His research has secured sustained funding from NSF, NIH, and other agencies supporting theoretical advances in control frameworks and their applications to biomedical systems, network infrastructure, and environmental modeling. The SBML initiative exemplifies his group's impact in standardizing computational biology research. He leads a highly collaborative research ecosystem at Caltech that integrates engineers, biologists, neuroscientists, and computer scientists to develop universal principles for complex networks. Current efforts focus on translating theoretical insights into health technologies, resilient infrastructure, and climate-responsive systems through the application of robust-efficiency frameworks to emerging challenges in cyber-physical and biological domains.

Sharon RozovskyView profile

Professor

• Oxidative Stress
• Protein Quality Control
• ERAD Pathway
• +5 more

Sharon Rozovsky is a Professor in the Department of Chemistry and Biochemistry at the University of Delaware's College of Arts & Sciences, where she leads research on oxidative stress response mechanisms and protein quality control pathways. Her work bridges biochemistry, chemical biology, and structural biology with direct implications for understanding neurodegenerative diseases and viral pathogenesis. Her academic foundation includes a B.S. from Tel Aviv University (1994) and a Ph.D. from Columbia University (2000), establishing her expertise in protein dynamics and redox biochemistry. These credentials underpin her innovative approaches to studying cellular stress responses. Rozovsky's research program centers on selenoproteins—proteins containing the rare amino acid selenocysteine—and their critical roles in endoplasmic reticulum (ER) stress resolution. She investigates how membrane-bound selenoproteins like Selenoprotein S and K regulate the ER-associated degradation (ERAD) pathway, with recent work revealing their surprising autoproteolytic activity and involvement in SARS-CoV-2 replication. Her lab pioneers chemical tools including expressed protein ligation and advanced 77Se NMR spectroscopy to characterize these systems at molecular resolution. Analysis of her 2021-2025 publications shows dominant themes in selenoprotein structure-function relationships, ER stress mechanisms, and viral interactions, alongside methodological innovations in cryo-EM grid technology and NMR. This body of work demonstrates consistent focus on redox biochemistry with expanding applications in virology and structural biology. No major scientific awards or fellowships were explicitly documented in the available materials, though her research impact is evident through high-impact publications and methodological contributions. She directs the active Rozovsky Research Group, mentoring graduate students and postdoctoral researchers in biochemical and biophysical techniques. Her laboratory operations are supported by competitive funding including an NSF CAREER award (2011) focused on selenoprotein reactivity, reflecting sustained recognition of her innovative research program.