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• Epigenetics
• Retroelements
• Transposable elements
• +5 more

Didier Trono is a Full Professor at École Polytechnique Fédérale de Lausanne (EPFL), where he leads the Laboratory of Virology and Genetics (LVG) within the School of Life Sciences. Formerly, from 2004 to 2012, he served as the founding dean of EPFL's Faculty of Life Sciences, orchestrating its development and growth during this formative period. Trono received his medical education at the University of Geneva, followed by clinical training in pathology, internal medicine, and infectious diseases in Geneva and at Massachusetts General Hospital in Boston. His scientific career began at the Whitehead Institute of MIT, and in 1990 he was recruited by the Salk Institute of San Diego to launch an AIDS research center. After seven years in the United States, he returned to Europe and eventually joined EPFL. Dr. Trono's research has evolved significantly over his career. Initially focusing on virus-host interactions, he studied pathogens like HIV and Hepatitis B virus, creating HIV-derived genetic transfer tools that are now successfully used in gene therapy. For approximately the last fifteen years, his research has centered on epigenetics, particularly exploring the impact of retroelements and their control mechanisms on development and physiology of higher organisms, including humans. His laboratory investigates how transposable elements and KRAB zinc finger proteins regulate gene expression, with important implications for understanding cancer biology and developing new diagnostic and therapeutic approaches. Analysis of his recent publications (2022-2024) reveals a strong focus on transposable elements, KRAB zinc finger proteins, and their roles in gene regulation and cancer. His work combines molecular biology, genomics, and bioinformatics approaches to understand how these ancient viral remnants have been co-opted by the host genome to regulate development and cellular functions. The research spans basic molecular mechanisms to potential clinical applications in cancer diagnosis and therapy, with some recent work also addressing SARS-CoV-2 and immune responses. Throughout his career, Professor Trono has mentored numerous PhD students, including Bojkowska Karolina, Brandão Sanches Vong Martins Filipe Amândio, Bulliard Yannick, Coluccio Andrea, Corsinotti Andrea, Coudray Alexandre, De Tribolet-Hardy Jonas Caspar, and Dorschel Iris Arianna. His laboratory has received significant funding to support research at the intersection of virology, genetics, and epigenetics, contributing to EPFL's reputation as a leading institution in life sciences research. The Trono Laboratory continues to be at the forefront of research on retroelements and their regulatory mechanisms, maintaining a vibrant research environment that bridges fundamental biological questions with potential medical applications, particularly in cancer research and precision medicine.

Harris H. WangView profile

Associate Professor

• Systems Biology
• Synthetic Biology
• Genome Engineering
• +17 more

Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.

Romain LopezView profile

Assistant Professor

• Single-cell omics
• Spatial transcriptomics
• Deep generative models
• +5 more

Romain Lopez is an Assistant Professor of Computer Science and Biology at New York University, with a joint appointment in the Courant Institute of Mathematical Sciences and the Department of Biology. He will be joining NYU in September 2025, bringing expertise at the intersection of machine learning and computational biology. Prior to joining NYU, he was a Postdoctoral Fellow at Genentech and Stanford Medicine from 2021 to 2025, working with Jonathan Pritchard and Aviv Regev. Dr. Lopez received his educational training at prestigious institutions: PhD in Computer Science (2021) from the University of California, Berkeley, advised by Mike Jordan and Nir Yosef M.S. in Applied Mathematics (2016) from École polytechnique, Palaiseau, France Dr. Lopez's research focuses on developing machine learning methods to understand biological systems at the cellular level. His work bridges computational techniques with biological applications, particularly in single-cell and spatial omics analysis. He pioneered probabilistic approaches for single-cell analysis with scVI and co-developed scvi-tools, now widely adopted tools in the field. His research spans deep generative models, causal inference, perturbation modeling, and representation learning for biological data. His publication record demonstrates a consistent trajectory of innovation in computational biology, with recent work focusing on spatial biology, disentangled representations of cellular perturbations, and causal modeling of cellular responses. He has made significant contributions to the field of single-cell analysis, developing methods that help scientists interpret complex cellular data and predict how cells respond to various perturbations. Dr. Lopez has received numerous honors and awards for his research: Best Paper Award from the ICML Workshop on AI for Science (2024) Best Paper Award Honorable Mention from the AAAI Conference on Artificial Intelligence (2021) Best Student Poster Award from the ICML Workshop on Computational Biology (2019) UC Berkeley EECS Departmental Graduate Fellowship (2016) Carnot Foundation Fellowship (2016) Monahan Foundation Fellowship (2016) French National Defence Medal, Bronze Echelon (2014) At NYU, Dr. Lopez will lead the Biological Machine Learning group, which develops probabilistic machine learning methods to uncover biological mechanisms governing cellular behavior and disease. His lab focuses on creating tools that transform complex cellular data into biological insights, with applications in understanding cancer, immune responses, and fundamental cellular processes. His work has significant implications for precision medicine and drug discovery.

Adam RunionsView profile

Researcher

• Computational Modeling
• Developmental Biology
• Computer Science
• +4 more

Adam Runions is a researcher in the Department of Computer Science at the University of Calgary, leading the MPG Partner Group in computational analysis of leaf development through collaborative work with Miltos Tsiantis. His group is embedded in the Graphics Cluster, focusing on interdisciplinary problems at the intersection of computer science and developmental biology. University of Calgary - Department of Computer Science MPG Partner Group (2022) Graphics Cluster affiliation His research explores computational modeling and analysis of plant form and development across multiple scales, integrating geometric modeling, physically-based simulation, and computer-aided design. Key themes include plant morphogenesis, self-organization of natural forms, and cross-disciplinary applications in computer graphics and animation. Recent publications emphasize plant development (leaf shape, bark patterning), mathematical modeling (auxin-driven patterning), and geometric techniques (subdivision surfaces, PUPs). Collaborations span institutions like the Max Planck Institute for Plant Breeding Research. Scientific Awards Marie Sklodowska-Curie Fellowship Best Paper Award (International Conference on Cyberworlds 2015) Best Student Paper Award (Computer Graphics International 2011) The group actively recruits BSc, MSc, and PhD students with backgrounds in computer science and mathematics for projects on plant form simulation and digital content creation. Research integrates evolutionary biology, biomechanical modeling, and computational techniques.

John OakeyView profile

Professor

• Microfluidics
• Microscale transport phenomena
• Tissue engineering and regenerative medicine
• +4 more

John Oakey is a Professor and Graduate Coordinator in the Department of Chemical and Biomedical Engineering at the University of Wyoming, with additional affiliations to the INBRE Program, Molecular and Cellular Life Sciences Program, and Materials Science and Engineering Program. Education Postdoctoral Fellow, Center for Engineering in Medicine, Massachusetts General Hospital & Harvard Medical School (2007–2010) Ph.D. Chemical Engineering, Colorado School of Mines (2003) M.S. Chemical Engineering, Colorado School of Mines (1999) B.S. Chemical Engineering, Penn State University (1997) Research Interests Oakey’s laboratory integrates fluid dynamics, colloidal science and materials science to understand how biological systems behave under flow, on surfaces and within complex 3-D geometries. A unifying theme is the use of microfabrication and microfluidics to create new diagnostic, prognostic and therapeutic platforms. Current thrusts include: Heterogeneous biomaterials: self-assembled particulate tissue scaffolds whose mechanical and transport properties can be temporally programmed. Inertial microfluidics: exploiting lift forces for membrane-free particle sorting, enrichment and diagnostics. Multi-temporal analysis by flow cytometry: development of closed-loop, high-throughput microfluidic cytometers for longitudinal single-cell studies. Publication Trends From 2025 back to 2010, Oakey’s articles reveal a consistent trajectory that marries fundamental physics (microtubule mechanics, inertial focusing) with translational applications (cell encapsulation, tissue scaffolds, drug delivery). Recent work (2023-2025) increasingly targets injectable granular hydrogels, single-cell therapeutic delivery and sustainable carbon-sequestering living materials, demonstrating an evolution from microscale transport phenomena to macroscopic biomedical and environmental impact. Scientific Awards No named awards are listed in the supplied text. Advising & Coordination Roles As Graduate Coordinator for the Department of Chemical and Biomedical Engineering, Professor Oakey oversees graduate program development and student mentoring. While no individual students are named, his role implies active supervision of M.S. and Ph.D. advisees in chemical and biomedical engineering. Laboratory & Teams The Oakey Research Group operates from the Energy and Environmental Research Building (EERB 435A) at the University of Wyoming. The lab enjoys R1-level research infrastructure and collaborates broadly with the Wyoming INBRE network, the Molecular and Cellular Life Sciences Program, and the Materials Science and Engineering Program.

Adrien DesjardinsView profile

Professor

• Imaging and sensing
• Robotics
• Machine learning
• +6 more

Adrien Desjardins is a Professor at the University of British Columbia, jointly appointed in the Department of Mechanical Engineering and Department of Electrical and Computer Engineering within the Faculty of Applied Science. He joined UBC in 2024 after serving as a Full Professor at University College London from 2019-2024, following 13 years on faculty there. His educational background includes a B.Sc. from UBC (2001) and a Ph.D. from MIT and Harvard University (2007). Dr. Desjardins' research program focuses on interdisciplinary development of imaging and sensing modalities and autonomous robotics with marine and biomedical applications. His work integrates photonics, ultrasound, machine learning, and robotics to create innovative diagnostic tools and sensing systems, particularly in optical coherence tomography, diffuse optical spectroscopy, and photoacoustic imaging. His publication record reveals an evolution from foundational neuroimaging work (2001) toward increasingly sophisticated optical systems culminating in breakthroughs like ultrasensitive optical microresonators for ultrasound sensing (2017), demonstrating consistent innovation in biomedical optics with growing emphasis on machine learning integration and real-world applications. His scientific contributions have been recognized through prestigious awards: Research Chair from the Royal Academy of Engineering Healthcare Technologies Challenge Award from EPSRC Starting grants from ERC, EPSRC, and Royal Society World Economic Forum Young Scientist (2015) UCL Provost Teaching Prize (2013) Dr. Desjardins actively mentors graduate students and secures major research funding through competitive grants, with current openings for January/September 2025 intakes. His program involves close industry collaboration indicating strong translational focus, though specific lab names aren't mentioned. The interdisciplinary nature of his work suggests teams spanning engineering, computer science, and medical disciplines working on next-generation imaging systems for healthcare and marine exploration.

Vivek ShenoyView profile

Professor

• Mechanobiology
• Multiscale Modeling
• Biomaterials
• +6 more

Vivek Shenoy is the Eduardo D. Glandt President's Distinguished Professor at the University of Pennsylvania, with primary appointments in the Department of Materials Science and Engineering and secondary appointments in Bioengineering and Mechanical Engineering and Applied Mechanics. He leads the Multiscale Mechanobiology and Biomaterials Laboratory, which focuses on developing theoretical frameworks and numerical methods to understand complex biological and engineering systems across multiple length scales. Shenoy's research spans mechanobiology, chromatin organization, cell mechanics, and biomaterials. His work addresses the fundamental challenge of modeling how small-scale cellular phenomena couple with long-range tissue-level interactions across micrometers to centimeters. By integrating insights from soft matter physics, solid mechanics, chemistry, and applied mathematics, his group develops multiphysics continuum and mesoscale theories to elucidate mechanisms controlling both biological and engineering systems. His recent publications demonstrate an increasing focus on nuclear mechanics, chromatin organization, and the interplay between mechanical forces and gene regulation. Analysis of Shenoy's publication record reveals a strong interdisciplinary approach, with high-impact papers spanning biophysics, materials science, and cell biology. His work shows consistent evolution from fundamental mechanics of materials to complex biological systems, with recent emphasis on the mechanical regulation of chromatin architecture, cell migration dynamics in 3D environments, and mechanotransduction in development and disease. His publications appear regularly in top journals including Nature, Science, and their affiliated publications, demonstrating significant influence across multiple fields. Eduardo D. Glandt President's Distinguished Professor Multiple publications in Nature, Science, and PNAS Active research program with publications through 2025 Shenoy actively mentors students and postdocs through his laboratory, with numerous co-authored publications indicating strong mentorship. His research program appears to be well-funded through multiple grants supporting his work in mechanobiology and biomaterials. The Multiscale Mechanobiology and Biomaterials Laboratory maintains active collaborations across disciplines and institutions, reflecting the interdisciplinary nature of his research. The Multiscale Mechanobiology and Biomaterials Laboratory, housed within the Department of Materials Science and Engineering at the University of Pennsylvania, serves as the primary research hub for Shenoy's work. The lab maintains an active presence on social media (Twitter: @ShenoyLab) for updates on activities and publications. Their research approach combines theoretical modeling with experimental validation to address fundamental questions at the interface of mechanics, materials science, and biology.

Yaojun ZhangView profile

Assistant Professor

• Biological Physics
• Biophysics
• Theoretical Physics
• +3 more

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

• RNA Biology
• Myeloid Malignancies
• Hematology
• +4 more

Dr. Giulia Biancon is an Assistant Professor Adjunct in the Department of Medical Oncology and Hematology at Yale School of Medicine. She holds a PhD from the University of Milan (2019) and is a member of the Halene Lab, focusing on RNA biology and hematologic malignancies. Her research combines high-throughput methodologies to study RNA mechanisms in diseases like myeloid leukemias and splicing factor mutations. Education: PhD in Molecular Biology from the University of Milan (2019). Research Interests: RNA splicing, stress granules in cancer, epitranscriptomics, clonal hematopoiesis, and the interplay between genetic mutations and cellular pathways in blood cancers. Awards: 2024 Eclipse Award, 2022 ASH Abstract Achievement Award, and 2022 RNA Society Best Poster Award. Her work has been published in journals like Cell Reports , Blood , and Molecular Cell . Labs/Teams: Principal member of the Halene Lab and coordinator at the Yale Center for RNA Science and Medicine. Collaborates with institutions like the SeroNet network for immunology studies.

James BriscoeView profile

Professor

• Developmental Biology
• Molecular Signaling
• Transcriptional Networks
• +4 more

James Briscoe is a Senior Group Leader at The Francis Crick Institute in London, where he leads a research group focused on developmental biology and morphogen signaling. He previously held positions at the Medical Research Council's National Institute for Medical Research, which later became part of the Francis Crick Institute. Education: BSc in Microbiology and Virology from the University of Warwick, UK PhD from Imperial Cancer Research Fund/King's College London Postdoctoral training at Columbia University with Thomas Jessell Dr. Briscoe's research focuses on the molecular and cellular mechanisms of graded signaling by morphogens and the role of transcriptional networks in cell fate specification. His laboratory employs a range of experimental and computational techniques using model systems including mouse and chick embryos and embryonic stem cells. His work has significant implications for understanding developmental processes and their relationship to disease. His recent publications demonstrate a continued focus on morphogen gradients, neural tube development, and computational approaches to understanding cell fate decisions. His research increasingly integrates single-cell technologies and computational modeling to unravel the complexities of developmental patterning. Scientific Awards and Honors: EMBO Young Investigator (2001) EMBO Gold Medal (2008) Elected to EMBO (2009) Fellow of the Academy of Medical Sciences (2019) Fellow of the Royal Society (2019) As Editor-in-Chief of the journal Development since 2018, Dr. Briscoe plays a significant role in shaping the field of developmental biology. His leadership extends to mentoring researchers and contributing to scientific policy discussions, as evidenced by his recent publication 'Science under siege: protecting scientific progress in turbulent times.' Dr. Briscoe's laboratory at the Crick Institute is well-equipped with access to advanced facilities including light microscopy, flow cytometry, genomics, and computational resources, enabling a multidisciplinary approach to developmental biology questions.

Raul Astudillo MarbanView profile

Researcher

• Machine Learning
• Bayesian Optimization
• Decision-Making Systems
• +5 more

Raul Astudillo Marban is a Postdoctoral Scholar Research Associate in the Department of Computing and Mathematical Sciences at Caltech, hosted by Professor Yisong Yue. He will join MBZUAI as a tenure-track Assistant Professor in August 2025. His research focuses on adaptive learning and decision-making in complex, data-intensive environments, with applications in personalized healthcare, engineering design, and scientific discovery. He earned his Ph.D. in Operations Research and Information Engineering from Cornell University under Professor Peter Frazier and holds an undergraduate degree in Mathematics from the University of Guanajuato and the Center for Research in Mathematics. His work integrates Bayesian optimization and machine learning to address real-world challenges such as protein engineering, plant breeding, and computational biology. Key contributions include steering generative models with experimental data, preferential multi-objective optimization, and cost-aware Bayesian strategies. He has received recognition as a Rising Star in Management Science and Engineering (Stanford) and a Rising Star in Data Science (University of Chicago/UCSD). Recent research highlights include optimizing protein fitness through generative models, active learning in directed evolution, and Bayesian optimization for budget allocation in agriculture. His publications span top venues like NeurIPS, Nature Communications, and TMLR. He actively recruits students/researchers for projects in machine learning and optimization.

• Brain Plasticity
• Motor Learning
• Neurorehabilitation
• +5 more

Dr. Cassandra Sampaio Baptista is a Lecturer at the University of Glasgow's School of Psychology & Neuroscience. Her research focuses on brain plasticity in adulthood, particularly exploring how experiences like skill learning or rehabilitation influence structural and functional changes in the brain. She employs neuroimaging techniques such as fMRI neurofeedback and MRI to investigate mechanisms of myelin and white matter plasticity. Her work emphasizes translational applications, including stroke rehabilitation and promoting healthy aging. Key contributions include demonstrating myelin's role in motor learning and developing MRI protocols for white matter analysis. She collaborates on projects funded by the BIAL Foundation (2025–2026) and has supervised multiple postgraduate students. Recent publications highlight studies on oligodendrocyte dynamics, neurofeedback interventions for stroke survivors, and cross-species neuroscience approaches. While no specific awards are listed, her extensive publication record reflects her leadership in neuroplasticity research.

Lara FerryView profile

Professor

• Functional Morphology
• Aquatic Organisms
• Biomechanics
• +5 more

Lara Ferry is the Vice President of Research at Arizona State University (ASU), holding the title of President’s Professor. She is affiliated with the New College of Interdisciplinary Arts and Sciences, specifically the School of Mathematical and Natural Sciences, and serves as graduate faculty in the School of Life Sciences. Her roles include advancing research strategies, fostering interdisciplinary collaborations, and enhancing partnerships with institutions, communities, donors, and industry. Ferry is also a PLuS Alliance Fellow, a Senior Global Futures Scientist at the Global Institute of Sustainability and Innovation, and affiliated with the Biodesign Institute and Global Security Initiative. She holds honors faculty status in ASU’s Barrett Honors College. Her academic background includes a B.S. in Biology from Cal Poly State University, M.S. in Marine Science from San Francisco State University, Ph.D. in Ecology and Evolutionary Biology from UC Irvine, and postdoctoral work at UC Davis. Her research focuses on functional morphology, particularly the evolution of jaws and skeletal materials in aquatic organisms. She has contributed to understanding prey capture mechanisms in fish and the biomechanics of cartilage in elasmobranchs. Ferry’s awards include the 2016 Outstanding Faculty Mentor Award, 2014 Outstanding Research/Creative Activity Award, and the 2018 President’s Professor title. She has led initiatives in equity, diversity, and inclusion (JEDI) and served on boards of professional societies like the American Elasmobranch Society and Society for Integrative and Comparative Biology. Her editorial roles include Senior Executive Editor of Functional Ecology and editorial board memberships in journals like Integrative & Comparative Biology . Her research activity spans functional morphology, biomechanics, and marine physiology, with grants focused on interdisciplinary education and diversity in STEM. Notable projects include studies on cartilage strength in sharks and collaborations on cultural change in professional societies.

Raissa M. D'SouzaView profile

Professor

• Complex Networks
• Percolation Theory
• Cascades
• +3 more

Raissa M. D'Souza is a Professor and Associate Dean of Research in the College of Engineering at the University of California, Davis. She holds joint appointments in the Department of Computer Science, Department of Mechanical and Aerospace Engineering, Graduate Group in Applied Mathematics, and Graduate Group in Physics. Her research focuses on complex networks, percolation theory, cascades, and interdependent systems, with applications to social, biological, and technological networks. She leads the Networks and Control research group and is a Founding Lead Editor of Physical Review Research . Her work spans interdisciplinary collaborations, including with the Santa Fe Institute and the Complexity Sciences Hub Vienna. Key awards include Fellowships from AAAS (2024), APS (2016), and the Network Science Society (2019), as well as the Euler Award for her contributions to network science. Dr. D'Souza has advised over 10 PhD students and has secured grants from agencies including the NSF. Her lab explores topics like explosive percolation, synchronization in oscillator networks, and network controllability. Notable recent work includes studies on exotic synchronization patterns and strategies for mitigating cascading failures in interdependent systems.

Steven G. ClarkeView profile

Professor

• Biochemistry
• Systems Biology
• Biological Regulation
• +8 more

Dr. Steven G. Clarke is a Distinguished Professor at UCLA Department of Chemistry & Biochemistry and director of research at the Molecular Biology Institute . His work bridges protein chemistry , methylation biology , and aging research through studies of spontaneous protein damage and its repair mechanisms. Education: BA in Chemistry and Zoology, Pomona College (magna cum laude, Phi Beta Kappa) PhD in Biochemistry and Molecular Biology, Harvard University (NSF Fellow) Postdoctoral Fellowship at UC Berkeley (Miller Fellow) Dr. Clarke's research focuses on protein isoaspartyl repair via PCMT1/PIMT enzymes , ribosomal protein methylation in Saccharomyces cerevisiae , and PRMT family characterization including PRMT7 and PRMT9. His lab combines biochemical assays , genetic models , and structural analysis to investigate aging mechanisms and disease implications. Recent publications highlight: COQ5 structure-function analysis in coenzyme Q biosynthesis PCMTD1 ubiquitin ligase interactions PRMT7 substrate specificity in histone H2B Protein isoaspartyl impacts on T cell function in lupus Novel PRMT inhibitors for cancer therapy Methionine addiction in osteosarcoma malignancy Major scientific awards: American Chemical Society Ralph F. Hirschmann Award in Peptide Chemistry NIH MERIT Award Ellison Medical Foundation Senior Scholar Award William C. Rose Award, ASBMB UCLA Distinguished Teaching Award (Eby Award winner) Current lab members include PhD candidates Eric Pang (UCSB) and Sining "Cindy" Wang (UCLA), while undergraduates Celeste Medina-Seymoure , Elizabeth Oroudjeva , Olivia Pacheco , and Jasmine Winter contribute to ongoing proteostasis studies. Collaborations with Profs. Jose Rodriguez and Catherine Clarke demonstrate interdisciplinary research approaches.